产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
乳腺癌1号基因抗体(6B4)
目录 :
NB100-404
规格 :
100微升
价格 :
459美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6B4
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 8
参考文献
Swift M, Azizkhan Clifford J. DNA damage-induced sumoylation of Sp1 induces its interaction with RNF4 and degradation in S phase to remove 53BP1 from DSBs and permit HR. DNA Repair (Amst). 2022;111:103289 pubmed 出版商
Swift M, Beishline K, Flashner S, Azizkhan Clifford J. DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1. Cell Rep. 2021;34:108840 pubmed 出版商
Zhai B, Li Y, Kotapalli S, Bacha J, Brown D, Steinø A, et al. Dianhydrogalactitol synergizes with topoisomerase poisons to overcome DNA repair activity in tumor cells. Cell Death Dis. 2020;11:577 pubmed 出版商
Mori S, Honda H, Ishii T, Yoshimura M, Sasagasako N, Suzuki S, et al. Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease. Neuropathology. 2019;39:358-367 pubmed 出版商
Zhai B, Steinø A, Bacha J, Brown D, Daugaard M. Dianhydrogalactitol induces replication-dependent DNA damage in tumor cells preferentially resolved by homologous recombination. Cell Death Dis. 2018;9:1016 pubmed 出版商
Berger A, Cortese G, Amodeo K, Weihofen A, Letai A, LaVoie M. Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release. Hum Mol Genet. 2009;18:4317-28 pubmed 出版商
Bernard Gallon D, Dechelotte P, Le Corre L, Chalabi N, Vissac Sabatier C, Bignon Y. Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia. Anticancer Res. 2004;24:321-4 pubmed
Li S, Ting N, Zheng L, Chen P, Ziv Y, Shiloh Y, et al. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature. 2000;406:210-5 pubmed
产品信息
品牌 :
Novus
MasterCode :
NB100-404
SKU号 :
NB100-404
产品名称 :
乳腺癌1号基因抗体(6B4)
描述 :
The BRCA1 Antibody (6B4) from NB100-404 is a nb100-404 antibody to . This antibody reacts with apoptosis, breast cancer, cancer, dna double strand break repair, dna repair, homologous recombination, tumor suppressors, zinc finger.
靶标 :
乳腺癌1号基因
类别 :
一抗
单位尺寸 :
100微升
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
6B4
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
BRCA1 protein fragment expressed in E. coli corresponding to amino acids 341-748.
抗体亚型 :
IgG1
纯度 :
蛋白质G纯化
物种 :
人类
特异性 :
This recognizes BRCA1, a 220-kDa nuclear phosphoprotein, and does not recognize the exon 11 splice variant
理论上的分子量 :
220 kDa
基因符号 :
乳腺癌1号基因
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(6B4)-Western-Blot-NB100-404-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(6B4)-Immunocytochemistry-Immunofluorescence-NB100-404-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(6B4)-Immunohistochemistry-NB100-404-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(6B4)-Chromatin-Immunoprecipitation-NB100-404-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(6B4)-Western-Blot-NB100-404-img0002.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(6B4)-Western-Blot-NB100-404-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(6B4)-Immunoprecipitation-NB100-404-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(6B4)-Knockdown-Validated-NB100-404-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(6B4)-Knockout-Validated-NB100-404-img0015.jpg
应用 :
免疫印迹, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡, 染色质免疫沉淀 (ChIP), 基因敲除验证, 基因敲减验证
美元 :
459美元
别名 :
BRCAI, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein, breast cancer 1, early onset, breast cancer type 1 susceptibility protein, EC 6.3.2, EC 6.3.2.-, IRIS, PNCA4, PSCP, subunit 1
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。