产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
WRN抗体
目录 :
NB100-471
规格 :
100微升
价格 :
469美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 免疫沉淀; 人类; 图 1c
  • 免疫印迹; 人类; 图 3c
Liu B, Yi J, Yang X, Liu L, Lou X, Zhang Z, et al. MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent manner. Oncogene. 2019;38:2501-2515 pubmed 出版商
Datta A, Biswas K, Sommers J, Thompson H, Awate S, Nicolae C, et al. WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells. Nat Commun. 2021;12:6561 pubmed 出版商
Strassheim D, Karoor V, Nijmeh H, Weston P, Lapel M, Schaack J, et al. c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells. Cells. 2020;9: pubmed 出版商
Gericke A, Mann C, Zadeh J, Musayeva A, Wolff I, Wang M, et al. Elevated Intraocular Pressure Causes Abnormal Reactivity of Mouse Retinal Arterioles. Oxid Med Cell Longev. 2019;2019:9736047 pubmed 出版商
Zadeh J, Ruemmler R, Hartmann E, Ziebart A, Ludwig M, Patzak A, et al. Responses of retinal arterioles and ciliary arteries in pigs with acute respiratory distress syndrome (ARDS). Exp Eye Res. 2019;184:152-161 pubmed 出版商
Serganova I, Cohen I, Vemuri K, Shindo M, Maeda M, Mane M, et al. LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response. PLoS ONE. 2018;13:e0203965 pubmed 出版商
Hayashi K, Tasaka T, Kondo T, Ishikawa Y, Goto M, Matsuhashi Y, et al. Successful Cord Blood Transplantation in a Werner Syndrome Patient with High-risk Myelodysplastic Syndrome. Intern Med. 2019;58:109-113 pubmed 出版商
Bouchard G, Therriault H, Geha S, Bujold R, Saucier C, Paquette B. Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model. Br J Cancer. 2017;116:479-488 pubmed 出版商
Knudsen E, Balaji U, Freinkman E, McCue P, Witkiewicz A. Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential. Oncotarget. 2016;7:78396-78411 pubmed 出版商
De Bruycker S, Vangestel C, Van den Wyngaert T, Wyffels L, Wouters A, Pauwels P, et al. Baseline [(18)F]FMISO μPET as a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model. Mol Imaging Biol. 2016;18:606-16 pubmed 出版商
Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, et al. DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol. 2015;208:545-62 pubmed 出版商
产品信息
品牌 :
Novus
MasterCode :
NB100-471
SKU号 :
NB100-471
产品名称 :
WRN抗体
描述 :
The WRN Antibody from NB100-471 is a nb100-471 antibody to . This antibody reacts with cancer, dna repair, genes sensitive to dna damaging agents, tumor suppressors. The WRN Antibody has been validated for the following applications: Q14191.
靶标 :
WRN
类别 :
一抗
单位尺寸 :
100微升
缓冲液 :
三羟甲基氨基甲烷柠檬酸盐/磷酸盐(pH值7.0-8.0)
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
兔
免疫原 :
The immunogen recognized by this antibody maps to a region between residues 400 and 450 of human Werner Syndrome Helicase using the numbering given in SwissProt entry Q14191 (GeneID 7486).
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类
基因符号 :
WRN
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/WRN-Antibody-Western-Blot-NB100-471-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/WRN-Antibody-Immunocytochemistry-Immunofluorescence-NB100-471-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/WRN-Antibody-Western-Blot-NB100-471-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/WRN-Antibody-Western-Blot-NB100-471-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/WRN-Antibody-Western-Blot-NB100-471-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/WRN-Antibody-Immunoprecipitation-NB100-471-img0008.jpg
accessionNumbers :
Q14191
应用 :
Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Chromatin Immunoprecipitation (ChIP)
美元 :
469美元
别名 :
DKFZp686C2056, DNA helicase, RecQ-like type 3, EC 3.1, EC 3.6.1, EC 3.6.4.12, Exonuclease WRN, RecQ protein-like 2, RecQ3, RECQ3RECQL3, RECQL2Werner syndrome ATP-dependent helicase, Werner syndrome, Werner syndrome, RecQ helicase-like
储存 :
存放在4C。 不冻结
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。