产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
WRN抗体
目录 :
NB100-472
规格 :
100微升
价格 :
469美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
32.1
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫沉淀, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 13
出版应用/物种/样本/稀释参考文献
  • 免疫印迹基因敲除验证; 人类; 1:1000; 图 4a, e3a
  • 免疫印迹; 人类; 1:1000; 图 2e, e7e, e10b
Chan E, Shibue T, McFarland J, Gaeta B, Ghandi M, Dumont N, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. 2019;568:551-556 pubmed 出版商
Emam A, Wu X, Xu S, Wang L, Liu S, Wang B. Stalled replication fork protection limits cGAS-STING and P-body-dependent innate immune signalling. Nat Cell Biol. 2022;24:1154-1164 pubmed 出版商
Wu X, Li Y, Liu X, Chen C, Harrington S, Cao S, et al. Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy. Heliyon. 2018;4:e01039 pubmed 出版商
Meunier M, Scandolera A, Chapuis E, Lambert C, Jarrin C, Robe P, et al. From stem cells protection to skin microbiota balance: Orobanche rapum extract, a new natural strategy. J Cosmet Dermatol. 2019;18:1140-1154 pubmed 出版商
Hori M, Miki T, Okamoto M, Yazama F, Konishi H, Kaneko H, et al. The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer. PLoS ONE. 2013;8:e55710 pubmed 出版商
Güvenç H, Pavlyukov M, Joshi K, Kurt H, Banasavadi Siddegowda Y, Mao P, et al. Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex. Clin Cancer Res. 2013;19:631-42 pubmed 出版商
Lechler P, Schaumburger J, Köck F, Balakrishnan S, Doukas S, Prantl L, et al. The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells. Calcif Tissue Int. 2011;89:211-20 pubmed 出版商
Lechler P, Renkawitz T, Campean V, Balakrishnan S, Tingart M, Grifka J, et al. The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro. BMC Cancer. 2011;11:120 pubmed 出版商
Qi G, Tuncel H, Aoki E, Tanaka S, Oka S, Kaneko I, et al. Intracellular localization of survivin determines biological behavior in colorectal cancer. Oncol Rep. 2009;22:557-62 pubmed
Lechler P, Wu X, Bernhardt W, Campean V, Gastiger S, Hackenbeck T, et al. The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney. Am J Pathol. 2007;171:1483-98 pubmed
Ding Y, Prieto V, Zhang P, Rosenthal S, Smith K, Skelton H, et al. Nuclear expression of the antiapoptotic protein survivin in malignant melanoma. Cancer. 2006;106:1123-9 pubmed
Giodini A, Kallio M, Wall N, Gorbsky G, Tognin S, Marchisio P, et al. Regulation of microtubule stability and mitotic progression by survivin. Cancer Res. 2002;62:2462-7 pubmed
Fortugno P, Wall N, Giodini A, O Connor D, Plescia J, Padgett K, et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci. 2002;115:575-85 pubmed
产品信息
品牌 :
Novus
MasterCode :
NB100-472
SKU号 :
NB100-472
产品名称 :
WRN抗体
描述 :
The WRN Antibody from NB100-472 is a nb100-472 antibody to . This antibody reacts with cancer, dna repair, genes sensitive to dna damaging agents, tumor suppressors. The WRN Antibody has been validated for the following applications: Q14191.
靶标 :
WRN
类别 :
一抗
单位尺寸 :
100微升
缓冲液 :
三羟甲基氨基甲烷柠檬酸盐/磷酸盐(pH值7.0-8.0)
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
The immunogen recognized by this antibody maps to a region between residues 1400 and the C-terminus (residue 1432) of human Werner Syndrome Helicase using the numbering given in SwissProt entry Q14191 (GeneID 7486).
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠
理论上的分子量 :
162 kDa
基因符号 :
WRN
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/WRN-Antibody-Western-Blot-NB100-472-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/WRN-Antibody-Western-Blot-NB100-472-img0004.jpg
accessionNumbers :
Q14191
应用 :
免疫印迹, 免疫沉淀, 基因敲除验证
美元 :
469美元
别名 :
DKFZp686C2056, DNA helicase, RecQ-like type 3, EC 3.1, EC 3.6.1, EC 3.6.4.12, Exonuclease WRN, RecQ protein-like 2, RecQ3, RECQ3RECQL3, RECQL2Werner syndrome ATP-dependent helicase, Werner syndrome, Werner syndrome, RecQ helicase-like
储存 :
存放在4C。 不冻结
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。