产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
HIF-1甲抗体
目录 :
NB100-479
规格 :
0.1 ml (also 0.025 ml)
价格 :
349美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
Alexa Fluor系列荧光染料405
克隆名称 :
OTI2B3
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 186
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠; 1:200; 图 4a
  • 免疫印迹; 大鼠; 1:10,000; 图 s1a
Li J, Tao T, Xu J, Liu Z, Zou Z, Jin M. HIF‑1α attenuates neuronal apoptosis by upregulating EPO expression following cerebral ischemia‑reperfusion injury in a rat MCAO model. Int J Mol Med. 2020;45:1027-1036 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Guo H, Ci X, Ahmed M, Hua J, Soares F, Lin D, et al. ONECUT2 is a driver of neuroendocrine prostate cancer. Nat Commun. 2019;10:278 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 s4a
Aoki A, Nakashima A, Kusabiraki T, Ono Y, Yoshino O, Muto M, et al. Trophoblast-Specific Conditional Atg7 Knockout Mice Develop Gestational Hypertension. Am J Pathol. 2018;188:2474-2486 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 2o
Takai K, Drain A, Lawson D, Littlepage L, Karpuj M, Kessenbrock K, et al. Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes Dev. 2018;32:244-257 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 表 s1
Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda Andoh T, et al. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Stem Cell Reports. 2017;8:1743-1756 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Myllymäki M, Määttä J, Dimova E, Izzi V, Väisänen T, Myllyharju J, et al. Notch Downregulation and Extramedullary Erythrocytosis in Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2-Deficient Mice. Mol Cell Biol. 2017;37: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2c
Guimarães T, Farias L, Santos E, De Carvalho Fraga C, Orsini L, de Freitas Teles L, et al. Metformin increases PDH and suppresses HIF-1? under hypoxic conditions and induces cell death in oral squamous cell carcinoma. Oncotarget. 2016;7:55057-55068 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Ruf M, Moch H, Schraml P. PD-L1 expression is regulated by hypoxia inducible factor in clear cell renal cell carcinoma. Int J Cancer. 2016;139:396-403 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5
Zhou F, Dai A, Jiang Y, Tan X, Zhang X. SENP‑1 enhances hypoxia‑induced proliferation of rat pulmonary artery smooth muscle cells by regulating hypoxia‑inducible factor‑1α. Mol Med Rep. 2016;13:3482-90 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Regan Anderson T, Ma S, Raj G, Cidlowski J, Helle T, Knutson T, et al. Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer. Cancer Res. 2016;76:1653-63 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4
  • 免疫印迹; 人类; 1:500; 图 3
Aquino Gálvez A, González Ávila G, Delgado Tello J, Castillejos López M, Mendoza Milla C, Zúñiga J, et al. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia. Oncol Rep. 2016;35:577-83 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Valbuena G, Rizzardini M, Cimini S, Siskos A, Bendotti C, Cantoni L, et al. Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis. Mol Neurobiol. 2016;53:2222-40 pubmed 出版商
Casciello F, Al Ejeh F, Miranda M, Kelly G, Baxter E, Windloch K, et al. G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome. Theranostics. 2020;10:4515-4529 pubmed 出版商
Sharma M, Boytard L, Hadi T, Koelwyn G, Simon R, Ouimet M, et al. Enhanced glycolysis and HIF-1α activation in adipose tissue macrophages sustains local and systemic interleukin-1β production in obesity. Sci Rep. 2020;10:5555 pubmed 出版商
Grassi E, Pantazopoulou V, Pietras A. Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma. Oncogene. 2020;39:4028-4044 pubmed 出版商
Fitzpatrick S, Lambden S, Macías D, Puthucheary Z, Pietsch S, Mendil L, et al. 2-Hydroxyglutarate Metabolism Is Altered in an in vivo Model of LPS Induced Endotoxemia. Front Physiol. 2020;11:147 pubmed 出版商
Ukeba D, Sudo H, Tsujimoto T, Ura K, Yamada K, Iwasaki N. Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs. EBioMedicine. 2020;53:102698 pubmed 出版商
Laitakari A, Huttunen R, Kuvaja P, Hannuksela P, Szabo Z, Heikkilä M, et al. Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span. FASEB J. 2020;34:5590-5609 pubmed 出版商
Ajime T, Serré J, Wüst R, Messa G, Poffé C, Swaminathan A, et al. Two weeks smoking cessation reverses cigarette smoke-induced skeletal muscle atrophy and mitochondrial dysfunction in mice. Nicotine Tob Res. 2020;: pubmed 出版商
Klee K, Storti F, Maggi J, Todorova V, Karademir D, Berger W, et al. The Expression of Decidual Protein Induced by Progesterone (DEPP) is Controlled by Three Distal Consensus Hypoxia Responsive Element (HRE) in Hypoxic Retinal Epithelial Cells. Genes (Basel). 2020;11: pubmed 出版商
Roelants C, Pillet C, Franquet Q, Sarrazin C, Peilleron N, Giacosa S, et al. Ex-Vivo Treatment of Tumor Tissue Slices as a Predictive Preclinical Method to Evaluate Targeted Therapies for Patients with Renal Carcinoma. Cancers (Basel). 2020;12: pubmed 出版商
Fine J, Kosyakovsky J, Baillargeon A, Tokarev J, Cooner J, Svitak A, et al. Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non-disease-specific pathway of functional neurologic improvement. Brain Behav. 2020;10:e01536 pubmed 出版商
Persson C, von Stedingk K, Fredlund E, Bexell D, Påhlman S, Wigerup C, et al. ARNT-dependent HIF-2 transcriptional activity is not sufficient to regulate downstream target genes in neuroblastoma. Exp Cell Res. 2020;388:111845 pubmed 出版商
Chen X, Wu B, Wang S, Liu J, Gao H, Zhou F, et al. Hypoxia: involved but not essential for endometrial breakdown in mouse menstural-like model. Reproduction. 2020;159:133-144 pubmed 出版商
Valle Tenney R, Rebolledo D, Lipson K, Brandan E. Role of hypoxia in skeletal muscle fibrosis: Synergism between hypoxia and TGF-β signaling upregulates CCN2/CTGF expression specifically in muscle fibers. Matrix Biol. 2020;87:48-65 pubmed 出版商
Mahiddine K, Blaisdell A, Ma S, Créquer Grandhomme A, Lowell C, Erlebacher A. Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils. J Clin Invest. 2020;130:389-403 pubmed 出版商
Cannito S, Foglia B, Villano G, Turato C, Delgado T, Morello E, et al. SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets. Cancers (Basel). 2019;11: pubmed 出版商
Chavdoula E, Habiel D, Roupakia E, Markopoulos G, Vasilaki E, Kokkalis A, et al. CHUK/IKK-α loss in lung epithelial cells enhances NSCLC growth associated with HIF up-regulation. Life Sci Alliance. 2019;2: pubmed 出版商
Liou A, Liao C, Chou S, Chang Y, Chang C, Shih C. Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model. J Biomed Sci. 2019;26:93 pubmed 出版商
Lin Y, Huang S, Wu J, Chu T, Huang S, Lee C, et al. Novel HDGF/HIF-1α/VEGF axis in oral cancer impacts disease prognosis. BMC Cancer. 2019;19:1083 pubmed 出版商
Komabayashi Suzuki M, Yamanishi E, Watanabe C, Okamura M, Tabata H, Iwai R, et al. Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development. Cell Rep. 2019;29:1113-1129.e5 pubmed 出版商
Sampurno S, Chittleborough T, Carpinteri S, Hiller J, Heriot A, Lynch A, et al. Modes of carbon dioxide delivery during laparoscopy generate distinct differences in peritoneal damage and hypoxia in a porcine model. Surg Endosc. 2019;: pubmed 出版商
Bobek J, Oralová V, Kratochvilova A, Zvackova I, Lesot H, Matalova E. Tuftelin and HIFs expression in osteogenesis. Histochem Cell Biol. 2019;152:355-363 pubmed 出版商
Kataria N, Martinez C, Kerr B, Zaiter S, Morgan M, McAlpine S, et al. C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway. Cell Physiol Biochem. 2019;53:480-495 pubmed 出版商
Chau K, Bobek G, Xu B, Stait Gardner T, Price W, Hennessy A, et al. Effect of placental growth factor in models of experimental pre-eclampsia and trophoblast invasion. Clin Exp Pharmacol Physiol. 2019;: pubmed 出版商
Yekelchyk M, Guenther S, Preussner J, Braun T. Mono- and multi-nucleated ventricular cardiomyocytes constitute a transcriptionally homogenous cell population. Basic Res Cardiol. 2019;114:36 pubmed 出版商
Preston K, Rom I, Vrakas C, Landesberg G, Etwebi Z, Muraoka S, et al. Postprandial activation of leukocyte-endothelium interaction by fatty acids in the visceral adipose tissue microcirculation. FASEB J. 2019;33:11993-12007 pubmed 出版商
Magae J, Furukawa C, Kuwahara S, Jeong Y, Nakajima H, Chang Y. 4-O-methylascochlorin stabilizes hypoxia-inducible factor-1 in a manner different from hydroxylase inhibition by iron chelating or substrate competition. Biosci Biotechnol Biochem. 2019;83:2244-2248 pubmed 出版商
Adamska A, Domenichini A, Capone E, Damiani V, Akkaya B, Linton K, et al. Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer. J Exp Clin Cancer Res. 2019;38:312 pubmed 出版商
Choi S, Kim M, Yoon Y, Koh D, Kim M, Cho S, et al. Hypoxia-induced RelA/p65 derepresses SLC16A3 (MCT4) by downregulating ZBTB7A. Biochim Biophys Acta Gene Regul Mech. 2019;1862:771-785 pubmed 出版商
Stephens O, Weiss K, Frimel M, Rose J, Sun Y, Asosingh K, et al. Interdependence of hypoxia and β-adrenergic receptor signaling in pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2019;317:L369-L380 pubmed 出版商
Yamamoto A, Hester J, Macklin P, Kawai K, Uchiyama M, Biggs D, et al. Systemic silencing of PHD2 causes reversible immune regulatory dysfunction. J Clin Invest. 2019;130:3640-3656 pubmed 出版商
Matsuyama M, WuWong D, Horvath S, Matsuyama S. Epigenetic clock analysis of human fibroblasts in vitro: effects of hypoxia, donor age, and expression of hTERT and SV40 largeT. Aging (Albany NY). 2019;11:3012-3022 pubmed 出版商
Yao Q, Khan M, Merceron C, LaGory E, Tata Z, Mangiavini L, et al. Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate. Dev Cell. 2019;: pubmed 出版商
Adamska A, Ferro R, Lattanzio R, Capone E, Domenichini A, Damiani V, et al. ABCC3 is a novel target for the treatment of pancreatic cancer. Adv Biol Regul. 2019;: pubmed 出版商
Bechmann N, Poser I, Seifert V, Greunke C, Ullrich M, Qin N, et al. Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells. Cancers (Basel). 2019;11: pubmed 出版商
Cui D, Arima M, Hirayama T, Ikeda E. Hypoxia-induced disruption of neural vascular barrier is mediated by the intracellular induction of Fe(II) ion. Exp Cell Res. 2019;: pubmed 出版商
Delbrel E, Uzunhan Y, Soumare A, Gille T, Marchant D, Planes C, et al. ER Stress is Involved in Epithelial-To-Mesenchymal Transition of Alveolar Epithelial Cells Exposed to a Hypoxic Microenvironment. Int J Mol Sci. 2019;20: pubmed 出版商
Laitakari A, Ollonen T, Kietzmann T, Walkinshaw G, Mennerich D, Izzi V, et al. Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease. Redox Biol. 2019;22:101145 pubmed 出版商
Kondo T, Takeda K, Muko R, Ito A, Chang Y, Magae J, et al. 4-O-Methylascochlorin inhibits the prolyl hydroxylation of hypoxia-inducible factor-1α, which is attenuated by ascorbate. J Antibiot (Tokyo). 2019;72:271-281 pubmed 出版商
Merceron C, Ranganathan K, WANG E, Tata Z, Makkapati S, Khan M, et al. Hypoxia-inducible factor 2α is a negative regulator of osteoblastogenesis and bone mass accrual. Bone Res. 2019;7:7 pubmed 出版商
Yano M, Katoh T, Miyazawa M, Miyazawa M, Ogane N, Miwa M, et al. Clinicopathological correlation of ARID1A status with HDAC6 and its related factors in ovarian clear cell carcinoma. Sci Rep. 2019;9:2397 pubmed 出版商
Sato E, Maeda Y, Sato Y, Hinata A, Gomi H, Koga D, et al. Culture in 10% O2 enhances the production of active hormones in neuro-endocrine cells by up-regulating the expression of processing enzymes. Biochem J. 2019;476:827-842 pubmed 出版商
Chung Y, Luo A, Park K, Loonat A, Lakhal Littleton S, Robbins P, et al. Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity. JCI Insight. 2019;4: pubmed 出版商
Abu Remaileh M, Abu Remaileh M, Akkawi R, Knani I, Udi S, Pacold M, et al. WWOX somatic ablation in skeletal muscles alters glucose metabolism. Mol Metab. 2019;22:132-140 pubmed 出版商
Chen C, Sun J, Chen S, Liu Y, Zhu S, Wang Z, et al. A multifunctional-targeted nanoagent for dual-mode image-guided therapeutic effects on ovarian cancer cells. Int J Nanomedicine. 2019;14:753-769 pubmed 出版商
Adam R, Xia Z, Pravoverov K, Hong J, Case A, Schultz H, et al. Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure. Am J Physiol Heart Circ Physiol. 2019;316:H862-H872 pubmed 出版商
Simmen S, Cosin Roger J, Melhem H, Maliachovas N, Maane M, Baebler K, et al. Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal Epithelium. Cell Mol Gastroenterol Hepatol. 2019;7:339-355 pubmed 出版商
Ito F, Mori T, Tarumi Y, Okimura H, Kataoka H, Tanaka Y, et al. Equilin in conjugated equine estrogen increases monocyte-endothelial adhesion via NF-κB signaling. PLoS ONE. 2019;14:e0211462 pubmed 出版商
Martinez C, Kerr B, Jin C, Cistulli P, Cook K. Obstructive Sleep Apnea Activates HIF-1 in a Hypoxia Dose-Dependent Manner in HCT116 Colorectal Carcinoma Cells. Int J Mol Sci. 2019;20: pubmed 出版商
Vogel J, Thiel C, Tauber S, Stockmann C, Gassmann M, Ullrich O. Expression of Hypoxia-Inducible Factor 1α (HIF-1α) and Genes of Related Pathways in Altered Gravity. Int J Mol Sci. 2019;20: pubmed 出版商
Leinhos L, Peters J, Krull S, Helbig L, Vogler M, Lévay M, et al. Hypoxia suppresses myofibroblast differentiation by changing RhoA activity. J Cell Sci. 2019;132: pubmed 出版商
Williams A, Walton C, MacCannell K, Avelar A, Shohet R. HIF-1 regulation of miR-29c impairs SERCA2 expression and cardiac contractility. Am J Physiol Heart Circ Physiol. 2019;316:H554-H565 pubmed 出版商
Bíliková P, Svandova E, Veselá B, Doubek J, Poliard A, Matalova E. Coupling activation of pro-apoptotic caspases with autophagy in the Meckel´s cartilage. Physiol Res. 2019;68:135-140 pubmed
Han J, Lee J, Kong J, Ji Y, Kim J, Choe S, et al. Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor. Mol Cell Biol. 2019;39: pubmed 出版商
Wang Z, Yang K, Zheng Q, Zhang C, Tang H, Babicheva A, et al. Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2019;316:L216-L228 pubmed 出版商
Lam G, Sefton M. Hypoxia-inducible factor drives vascularization of modularly assembled engineered tissue. Tissue Eng Part A. 2018;: pubmed 出版商
Delbrel E, Soumare A, Naguez A, Label R, Bernard O, Bruhat A, et al. HIF-1α triggers ER stress and CHOP-mediated apoptosis in alveolar epithelial cells, a key event in pulmonary fibrosis. Sci Rep. 2018;8:17939 pubmed 出版商
Novoyatleva T, Kojonazarov B, Owczarek A, Veeroju S, Rai N, Henneke I, et al. Evidence for Fucoidan-P-selectin Axis as a Therapeutic Target on Hypoxia-induced Pulmonary Hypertension. Am J Respir Crit Care Med. 2018;: pubmed 出版商
Lee S, Abel E, Long F. Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. Nat Commun. 2018;9:4831 pubmed 出版商
Wang Y, Zhong S, Schofield C, Ratcliffe P, Lu X. Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively. J Cell Sci. 2018;131: pubmed 出版商
Chowdhury A, Aich A, Jain G, Wozny K, Lüchtenborg C, Hartmann M, et al. Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia. Cell Rep. 2018;25:561-570.e6 pubmed 出版商
Reddy S, Agarwal H, Barthwal M. Cilostazol ameliorates heart failure with preserved ejection fraction and diastolic dysfunction in obese and non-obese hypertensive mice. J Mol Cell Cardiol. 2018;123:46-57 pubmed 出版商
Burman A, Kropski J, Calvi C, Serezani A, Pascoalino B, Han W, et al. Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein. JCI Insight. 2018;3: pubmed 出版商
Heikal L, Ghezzi P, Mengozzi M, Ferns G. Assessment of HIF-1α expression and release following endothelial injury in-vitro and in-vivo. Mol Med. 2018;24:22 pubmed 出版商
Logue S, McGrath E, Cleary P, Greene S, Mnich K, Almanza A, et al. Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy. Nat Commun. 2018;9:3267 pubmed 出版商
Ow C, Ngo J, Ullah M, Barsha G, Meex R, Watt M, et al. Absence of renal hypoxia in the subacute phase of severe renal ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2018;315:F1358-F1369 pubmed 出版商
Tong B, Pantazopoulou V, Johansson E, Pietras A. The p75 neurotrophin receptor enhances HIF-dependent signaling in glioma. Exp Cell Res. 2018;371:122-129 pubmed 出版商
Wu J, Tsai H, Liu G, Wu C, Tai M. Autophagic cell death participates in POMC-induced melanoma suppression. Cell Death Discov. 2018;4:11 pubmed 出版商
Regan Anderson T, Ma S, Perez Kerkvliet C, Peng Y, Helle T, Krutilina R, et al. Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis. Mol Cancer Res. 2018;16:1761-1772 pubmed 出版商
Dai Z, Zhu M, Peng Y, Machireddy N, Evans C, Machado R, et al. Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in Pulmonary Arterial Hypertension with a HIF-2α Inhibitor. Am J Respir Crit Care Med. 2018;198:1423-1434 pubmed 出版商
Nascimento B, Bocco B, Fernandes G, Fonseca T, McAninch E, Cardoso C, et al. Induction of Type 2 Iodothyronine Deiodinase After Status Epilepticus Modifies Hippocampal Gene Expression in Male Mice. Endocrinology. 2018;159:3090-3104 pubmed 出版商
Nakazeki F, Nishiga M, Horie T, Nishi H, Nakashima Y, Baba O, et al. Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo. Sci Rep. 2018;8:8553 pubmed 出版商
Baay Guzman G, Durán Padilla M, Rangel Santiago J, Tirado Rodriguez B, Antonio Andres G, Barrios Payán J, et al. Dual role of hypoxia-inducible factor 1 α in experimental pulmonary tuberculosis: its implication as a new therapeutic target. Future Microbiol. 2018;13:785-798 pubmed 出版商
Chen A, Sceneay J, Godde N, Kinwel T, Ham S, Thompson E, et al. Intermittent hypoxia induces a metastatic phenotype in breast cancer. Oncogene. 2018;37:4214-4225 pubmed 出版商
Eskla K, Porosk R, Reimets R, Visnapuu T, Vasar E, Hundahl C, et al. Hypothermia augments stress response in mammalian cells. Free Radic Biol Med. 2018;121:157-168 pubmed 出版商
Raykhel I, Moafi F, Myllymäki S, Greciano P, Matlin K, Moyano J, et al. BAMBI is a novel HIF1-dependent modulator of TGF?-mediated disruption of cell polarity during hypoxia. J Cell Sci. 2018;131: pubmed 出版商
Barben M, Ail D, Storti F, Klee K, Schori C, Samardzija M, et al. Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress. Cell Death Differ. 2018;25:2071-2085 pubmed 出版商
Williams A, Khadka V, Tang M, Avelar A, Schunke K, Menor M, et al. HIF1 mediates a switch in pyruvate kinase isoforms after myocardial infarction. Physiol Genomics. 2018;50:479-494 pubmed 出版商
Wang T, Wei W, Mansai H, Huang C, Li L, Ye Q, et al. Overexpression of appoptosin promotes mitochondrial damage in MIN6 cells. Mol Med Rep. 2018;17:7149-7155 pubmed 出版商
Yamashita M, Ogasawara M, Kawasaki Y, Niisato M, Saito H, Kasai S, et al. Deficiency of protein-L-isoaspartate (D-aspartate) O-methyl-transferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal transition in lung adenocarcinoma. Oncotarget. 2018;9:13287-13300 pubmed 出版商
Cui H, Banerjee S, Guo S, Xie N, Liu G. IFN Regulatory Factor 2 Inhibits Expression of Glycolytic Genes and Lipopolysaccharide-Induced Proinflammatory Responses in Macrophages. J Immunol. 2018;200:3218-3230 pubmed 出版商
Zhu N, Yi B, Guo Z, Zhang G, Huang S, Qin Y, et al. Pim-1 Kinase Phosphorylates Cardiac Troponin I and Regulates Cardiac Myofilament Function. Cell Physiol Biochem. 2018;45:2174-2186 pubmed 出版商
Conotte S, Tassin A, Conotte R, Colet J, Zouaoui Boudjeltia K, Legrand A. Metabonomic profiling of chronic intermittent hypoxia in a mouse model. Respir Physiol Neurobiol. 2018;256:157-173 pubmed 出版商
Barben M, Schori C, Samardzija M, Grimm C. Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia. Mol Neurodegener. 2018;13:12 pubmed 出版商
Wong K, Beirowski B. Multiple lines of inhibitory feedback on AKT kinase in Schwann cells lacking TSC1/2 hint at distinct functions of mTORC1 and AKT in nerve development. Commun Integr Biol. 2018;11:e1433441 pubmed 出版商
Lin C, Kurashige M, Liu Y, Terabayashi T, Ishimoto Y, Wang T, et al. A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed. Sci Rep. 2018;8:2743 pubmed 出版商
Lennikov A, Mirabelli P, Mukwaya A, Schaupper M, Thangavelu M, Lachota M, et al. Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis. Angiogenesis. 2018;21:267-285 pubmed 出版商
Sodi V, Bacigalupa Z, Ferrer C, Lee J, Gocal W, Mukhopadhyay D, et al. Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation. Oncogene. 2018;37:924-934 pubmed 出版商
Buart S, Terry S, Noman M, Lanoy E, Boutros C, Fogel P, et al. Transcriptional response to hypoxic stress in melanoma and prognostic potential of GBE1 and BNIP3. Oncotarget. 2017;8:108786-108801 pubmed 出版商
Liu L, Liu W, Wang L, Zhu T, Zhong J, Xie N. Hypoxia-inducible factor 1 mediates intermittent hypoxia-induced migration of human breast cancer MDA-MB-231 cells. Oncol Lett. 2017;14:7715-7722 pubmed 出版商
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产品信息
品牌 :
Novus
SKU号 :
NB100-479
产品名称 :
HIF-1甲抗体
单位尺寸 :
0.1 ml (also 0.025 ml)
描述 :
The HIF-1 alpha Antibody from Novus is a rabbit polyclonal antibody to HIF-1 alpha. This antibody reacts with human, mouse, rat, porcine, canine, fish, hamster, primate, rabbit. The HIF-1 alpha Antibody has been validated for the following applications: Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Immunohistochemistry Whole-Mount.
靶标 :
HIF-1甲
类别 :
一抗
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
This HIF-1 alpha Antibody was developed against a fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [Uniprot# Q61221].
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠, 猪, 狗, 鱼类, 仓鼠, 灵长类动物, 兔
理论上的分子量 :
93 kDa
基因符号 :
缺氧诱导因子1A
catalog number base :
NB100-479
accessionNumbers :
Q61221
应用 :
Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Immunohistochemistry Whole-Mount
美元 :
349美元
applications abr :
WB, ChIP, Flow, IHC, ICC/IF, IP, IHC-P, IHC-Fr, IB, IHC-WhMt
别名 :
AINT, anti-HIF-1 alpha, anti-HIF1A, ARNT interacting protein, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF1, HIF-1 alpha, HIF1A, HIF-1A, HIF-1alpha, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1 subunit alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1, PAS domain-containing protein 8, PASD8
储存 :
存放在4C。 不冻结
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。