产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
HIF-1 alpha Antibody - BSA Free
目录 :
NB100-479
规格 :
0.1 ml (also 0.025 ml)
价格 :
449美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
Alexa Fluor系列荧光染料405
克隆名称 :
OTI2B3
反应物种 :
人类, 小鼠, 大鼠, , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 282
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 人类; 图 1d, s2
Wang Y, Lyu Y, Tu K, Xu Q, Yang Y, Salman S, et al. Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization. Sci Adv. 2021;7: pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 3a
Wang N, Peng Y, Su X, Prabhakar N, Nanduri J. Histone Deacetylase 5 Is an Early Epigenetic Regulator of Intermittent Hypoxia Induced Sympathetic Nerve Activation and Blood Pressure. Front Physiol. 2021;12:688322 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 s15
Choi Y, Kim Y, Oh S, Suh K, Kim Y, Lee G, et al. Senescent Tumor Cells Build a Cytokine Shield in Colorectal Cancer. Adv Sci (Weinh). 2021;8:2002497 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s7a
  • 免疫印迹; 人类; 1:1000; 图 5, s8a
Isomura H, Taguchi A, Kajino T, Asai N, Nakatochi M, Kato S, et al. Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1α regulator. Cancer Sci. 2021;: pubmed 出版商
  • 免疫组化; 大鼠; 1:200; 图 4a
  • 免疫印迹; 大鼠; 1:10,000; 图 s1a
Li J, Tao T, Xu J, Liu Z, Zou Z, Jin M. HIF‑1α attenuates neuronal apoptosis by upregulating EPO expression following cerebral ischemia‑reperfusion injury in a rat MCAO model. Int J Mol Med. 2020;45:1027-1036 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Guo H, Ci X, Ahmed M, Hua J, Soares F, Lin D, et al. ONECUT2 is a driver of neuroendocrine prostate cancer. Nat Commun. 2019;10:278 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 s4a
Aoki A, Nakashima A, Kusabiraki T, Ono Y, Yoshino O, Muto M, et al. Trophoblast-Specific Conditional Atg7 Knockout Mice Develop Gestational Hypertension. Am J Pathol. 2018;188:2474-2486 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 2o
Takai K, Drain A, Lawson D, Littlepage L, Karpuj M, Kessenbrock K, et al. Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes Dev. 2018;32:244-257 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 表 s1
Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda Andoh T, et al. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Stem Cell Reports. 2017;8:1743-1756 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Myllymäki M, Määttä J, Dimova E, Izzi V, Väisänen T, Myllyharju J, et al. Notch Downregulation and Extramedullary Erythrocytosis in Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2-Deficient Mice. Mol Cell Biol. 2017;37: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2c
Guimarães T, Farias L, Santos E, De Carvalho Fraga C, Orsini L, de Freitas Teles L, et al. Metformin increases PDH and suppresses HIF-1? under hypoxic conditions and induces cell death in oral squamous cell carcinoma. Oncotarget. 2016;7:55057-55068 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Ruf M, Moch H, Schraml P. PD-L1 expression is regulated by hypoxia inducible factor in clear cell renal cell carcinoma. Int J Cancer. 2016;139:396-403 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5
Zhou F, Dai A, Jiang Y, Tan X, Zhang X. SENP‑1 enhances hypoxia‑induced proliferation of rat pulmonary artery smooth muscle cells by regulating hypoxia‑inducible factor‑1α. Mol Med Rep. 2016;13:3482-90 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Regan Anderson T, Ma S, Raj G, Cidlowski J, Helle T, Knutson T, et al. Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer. Cancer Res. 2016;76:1653-63 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4
  • 免疫印迹; 人类; 1:500; 图 3
Aquino Gálvez A, González Ávila G, Delgado Tello J, Castillejos López M, Mendoza Milla C, Zúñiga J, et al. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia. Oncol Rep. 2016;35:577-83 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Valbuena G, Rizzardini M, Cimini S, Siskos A, Bendotti C, Cantoni L, et al. Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis. Mol Neurobiol. 2016;53:2222-40 pubmed 出版商
Samuel T, Rapic S, O Brien C, Edson M, Zhong Y, Dacosta R. Quantitative intravital imaging for real-time monitoring of pancreatic tumor cell hypoxia and stroma in an orthotopic mouse model. Sci Adv. 2023;9:eade8672 pubmed 出版商
Okuda C, Ueda Y, Muroi M, Sanada E, Osada H, Shiono Y, et al. Allantopyrone A interferes with the degradation of hypoxia-inducible factor 1α protein by reducing proteasome activity in human fibrosarcoma HT-1080 cells. J Antibiot (Tokyo). 2023;76:324-334 pubmed 出版商
Seike K, Kiledal A, Fujiwara H, Henig I, Burgos da Silva M, van den Brink M, et al. Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation. Immunity. 2023;56:353-368.e6 pubmed 出版商
Maki T, Sawahata M, Uta D, Irie K, Kume T. Chronic Treatment with Aβ42 with a Toxic Conformer and LPS Induces Inflammatory Responses in BV-2 Microglia with Dysregulation of Hypoxia-Inducible Factor Expression. Biol Pharm Bull. 2023;46:359-363 pubmed 出版商
Silwal P, Kim Y, Lee Y, Kim I, Jeon S, Roh T, et al. Chemical mimetics of the N-degron pathway alleviate systemic inflammation by activating mitophagy and immunometabolic remodeling. Exp Mol Med. 2023;55:333-346 pubmed 出版商
Chen Y, Zhang S, Ye L, Chen H, Yu L, Wu D. An Acute Bout of Exercise Suppresses Appetite via Central Lactate Metabolism. Neuroscience. 2023;510:49-59 pubmed 出版商
Bao S, Chen Z, Qin D, Xu H, Deng X, Zhang R, et al. Single-cell profiling reveals mechanisms of uncontrolled inflammation and glycolysis in decidual stromal cell subtypes in recurrent miscarriage. Hum Reprod. 2023;38:57-74 pubmed 出版商
Yang Y, Chen C, Zuo Q, Lu H, Salman S, Lyu Y, et al. NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification. Sci Adv. 2022;8:eabo5000 pubmed 出版商
Kim D, Khin P, Lim O, Jun H. LPA/LPAR1 signaling induces PGAM1 expression via AKT/mTOR/HIF-1α pathway and increases aerobic glycolysis, contributing to keratinocyte proliferation. Life Sci. 2022;311:121201 pubmed 出版商
Maki T, Sawahata M, Akutsu I, Amaike S, Hiramatsu G, Uta D, et al. APP Knock-In Mice Produce E22P-Aβ Exhibiting an Alzheimer's Disease-like Phenotype with Dysregulation of Hypoxia-Inducible Factor Expression. Int J Mol Sci. 2022;23: pubmed 出版商
Qian L, Rawashdeh O, Kasas L, Milne M, Garner N, Sankorrakul K, et al. Cholinergic basal forebrain degeneration due to sleep-disordered breathing exacerbates pathology in a mouse model of Alzheimer's disease. Nat Commun. 2022;13:6543 pubmed 出版商
Yin L, Zhang J, Sun Y. Early growth response-1 is a new substrate of the GSK3β-FBXW7 axis. Neoplasia. 2022;34:100839 pubmed 出版商
Soler Agesta R, Marco Brualla J, Minj xe1 rez S xe1 enz M, Yim C, Mart xed nez J xfa lvez M, Price M, et al. PT-112 Induces Mitochondrial Stress and Immunogenic Cell Death, Targeting Tumor Cells with Mitochondrial Deficiencies. Cancers (Basel). 2022;14: pubmed 出版商
Simmler P, Cortijo C, Koch L, Galliker P, Angori S, Bolck H, et al. SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer. Cell Rep. 2022;40:111266 pubmed 出版商
Chen J, Tang T, Cao J, Li Z, Zhong X, Wen Y, et al. KIM-1 augments hypoxia-induced tubulointerstitial inflammation through uptake of small extracellular vesicles by tubular epithelial cells. Mol Ther. 2022;: pubmed 出版商
Chang Y, Vuong C, Ngo N, Yamashita T, Ye X, Futamura Y, et al. Extracellular vesicles derived from Wharton's Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway. Sci Rep. 2022;12:13550 pubmed 出版商
Wang H, Wang X, Ma L, Huang X, Peng Y, Huang H, et al. PGC-1 alpha regulates mitochondrial biogenesis to ameliorate hypoxia-inhibited cementoblast mineralization. Ann N Y Acad Sci. 2022;1516:300-311 pubmed 出版商
Takiyama T, Sera T, Nakamura M, Hoshino M, Uesugi K, Horike S, et al. A maternal high-fat diet induces fetal origins of NASH-HCC in mice. Sci Rep. 2022;12:13136 pubmed 出版商
Li G, Li D, Wu C, Li S, Chen F, Li P, et al. Homocysteine-targeting compounds as a new treatment strategy for diabetic wounds via inhibition of the histone methyltransferase SET7/9. Exp Mol Med. 2022;54:988-998 pubmed 出版商
Ollonen T, Kurkela M, Laitakari A, Sakko S, Koivisto H, Myllyharju J, et al. Activation of the hypoxia response protects mice from amyloid-β accumulation. Cell Mol Life Sci. 2022;79:432 pubmed 出版商
Tapio J, Halmetoja R, Dimova E, M xe4 ki J, Laitala A, Walkinshaw G, et al. Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism. J Biol Chem. 2022;298:102222 pubmed 出版商
Chen M, Hu R, Cavinato C, Zhuang Z, Zhang J, Yun S, et al. Fibronectin-Integrin α5 Signaling in Vascular Complications of Type 1 Diabetes. Diabetes. 2022;71:2020-2033 pubmed 出版商
Li S, Li W, Yuan J, Bullova P, Wu J, Zhang X, et al. Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome. Nat Metab. 2022;4:739-758 pubmed 出版商
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Zhang R, Tiedemann K, Muthu M, Dinesh N, Komarova S, Ramkhelawon B, et al. Fibrillin-1-regulated miR-122 has a critical role in thoracic aortic aneurysm formation. Cell Mol Life Sci. 2022;79:314 pubmed 出版商
Baran N, Lodi A, Dhungana Y, Herbrich S, Collins M, Sweeney S, et al. Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Nat Commun. 2022;13:2801 pubmed 出版商
Salman S, Meyers D, Wicks E, Lee S, Datan E, Thomas A, et al. HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy. J Clin Invest. 2022;132: pubmed 出版商
Leigh T, Kawai T, Preston K, Kelemen S, Okune R, St Paul A, et al. Deletion of LDLRAP1 Induces Atherosclerotic Plaque Formation, Insulin Resistance, and Dysregulated Insulin Response in Adipose Tissue. Am J Pathol. 2022;192:1092-1108 pubmed 出版商
Wu X, Chen J, Liu C, Wang X, Zhou H, Mai K, et al. Slc38a9 Deficiency Induces Apoptosis and Metabolic Dysregulation and Leads to Premature Death in Zebrafish. Int J Mol Sci. 2022;23: pubmed 出版商
Xu Z, Wang C, He Y, Mao X, Zhang M, Hou Y, et al. Hypoxia-inducible factor protects against acute kidney injury via the Wnt/β-catenin signaling pathway. Am J Physiol Renal Physiol. 2022;322:F611-F624 pubmed 出版商
Kirschner K, Kelterborn S, Stehr H, Penzlin J, Jacobi C, Endesfelder S, et al. Adaptation of the Oxygen Sensing System during Lung Development. Oxid Med Cell Longev. 2022;2022:9714669 pubmed 出版商
Jatho A, Zieseniss A, Brechtel Curth K, Guo J, Böker K, Salinas G, et al. The HIFα-Stabilizing Drug Roxadustat Increases the Number of Renal Epo-Producing Sca-1+ Cells. Cells. 2022;11: pubmed 出版商
Snyder B, Wu H, Tillman B, Floyd T. Aged Mouse Hippocampus Exhibits Signs of Chronic Hypoxia and an Impaired HIF-Controlled Response to Acute Hypoxic Exposures. Cells. 2022;11: pubmed 出版商
Yang Y, Lu H, Chen C, Lyu Y, Cole R, Semenza G. HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia. Nat Commun. 2022;13:316 pubmed 出版商
Elamaa H, Kaakinen M, N xe4 tynki M, Szabo Z, Ronkainen V, xc4 ij xe4 l xe4 V, et al. PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis. Angiogenesis. 2022;25:259-274 pubmed 出版商
Michon S, Rodier F, Yu F. Targeted Anti-Cancer Provascular Therapy Using Ultrasound, Microbubbles, and Nitrite to Increase Radiotherapy Efficacy. Bioconjug Chem. 2022;33:1093-1105 pubmed 出版商
Röning T, Magga J, Laitakari A, Halmetoja R, Tapio J, Dimova E, et al. Activation of the hypoxia response pathway protects against age-induced cardiac hypertrophy. J Mol Cell Cardiol. 2022;164:148-155 pubmed 出版商
Borella R, De Biasi S, Paolini A, Boraldi F, Lo Tartaro D, Mattioli M, et al. Metabolic reprograming shapes neutrophil functions in severe COVID-19. Eur J Immunol. 2022;52:484-502 pubmed 出版商
Foglia B, Sutti S, Cannito S, Rosso C, Maggiora M, Autelli R, et al. Hepatocyte-Specific Deletion of HIF2α Prevents NASH-Related Liver Carcinogenesis by Decreasing Cancer Cell Proliferation. Cell Mol Gastroenterol Hepatol. 2022;13:459-482 pubmed 出版商
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Wang J, Zhang H, Kaul A, Li K, Priyandoko D, Kaul S, et al. Effect of Ashwagandha Withanolides on Muscle Cell Differentiation. Biomolecules. 2021;11: pubmed 出版商
Pang L, Ng K, Liu J, Yeung W, Zhu J, Chiu T, et al. Plasmacytoid dendritic cells recruited by HIF-1α/eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma. Cancer Lett. 2021;522:80-92 pubmed 出版商
Jeny F, Bernaudin J, Valeyre D, Kambouchner M, Pretolani M, Nunes H, et al. Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis. Front Immunol. 2021;12:719009 pubmed 出版商
Helena J, Joubert A, Mabeta P, Coetzee M, Lakier R, Mercier A. Intracellular Signaling Responses Induced by Radiation within an In Vitro Bone Metastasis Model after Pre-Treatment with an Estrone Analogue. Cells. 2021;10: pubmed 出版商
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Nanduri J, Wang N, Wang B, Prabhakar N. Lysine demethylase KDM6B regulates HIF-1α mediated systemic and cellular responses to intermittent hypoxia. Physiol Genomics. 2021;: pubmed 出版商
Ju S, Lim L, Wi K, Park C, Ki Y, Choi D, et al. LRP5 Regulates HIF-1α Stability via Interaction with PHD2 in Ischemic Myocardium. Int J Mol Sci. 2021;22: pubmed 出版商
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Grubman A, Choo X, Chew G, Ouyang J, Sun G, Croft N, et al. Transcriptional signature in microglia associated with Aβ plaque phagocytosis. Nat Commun. 2021;12:3015 pubmed 出版商
Bae W, Choi J, Nam S, Jeong J. β-arrestin 2 stimulates degradation of HIF-1α and modulates tumor progression of glioblastoma. Cell Death Differ. 2021;28:3092-3104 pubmed 出版商
Silwal P, Kim J, Jeon S, Lee J, Kim Y, Kim Y, et al. Mitofusin-2 boosts innate immunity through the maintenance of aerobic glycolysis and activation of xenophagy in mice. Commun Biol. 2021;4:548 pubmed 出版商
Wang R, Godet I, Yang Y, Salman S, Lu H, Lyu Y, et al. Hypoxia-inducible factor-dependent ADAM12 expression mediates breast cancer invasion and metastasis. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
Xue Y, Wang S, Rana P, West E, Hong C, Feng H, et al. AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa. elife. 2021;10: pubmed 出版商
Pantazopoulou V, Jeannot P, Rosberg R, Berg T, Pietras A. Hypoxia-Induced Reactivity of Tumor-Associated Astrocytes Affects Glioma Cell Properties. Cells. 2021;10: pubmed 出版商
Yano M, Miyazawa M, Ogane N, Ogasawara A, Hasegawa K, Narahara H, et al. Up-regulation of HDAC6 Results in Poor Prognosis and Chemoresistance in Patients With Advanced Ovarian High-grade Serous Carcinoma. Anticancer Res. 2021;41:1647-1654 pubmed 出版商
Hutami I, Izawa T, Khurel Ochir T, Sakamaki T, Iwasa A, Tomita S, et al. HIF-1α controls palatal wound healing by regulating macrophage motility via S1P/S1P1 signaling axis. Oral Dis. 2021;: pubmed 出版商
Khuu M, Nallamothu T, Castro Rivera C, Arias Cavieres A, Szujewski C, Garcia Iii A. Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis. Sci Rep. 2021;11:6005 pubmed 出版商
Akyüz E, Doğanyiğit Z, Eroglu E, Moscovicz F, Merelli A, Lazarowski A, et al. Myocardial Iron Overload in an Experimental Model of Sudden Unexpected Death in Epilepsy. Front Neurol. 2021;12:609236 pubmed 出版商
Plastino F, Santana Garrido Á, Pesce N, Aronsson M, Lardner E, Mate A, et al. Echinomycin mitigates ocular angiogenesis by transcriptional inhibition of the hypoxia-inducible factor-1. Exp Eye Res. 2021;206:108518 pubmed 出版商
Tanimura A, Nakazato A, Tanaka N. MYD88 signals induce tumour-initiating cell generation through the NF-κB-HIF-1α activation cascade. Sci Rep. 2021;11:3991 pubmed 出版商
Pesce N, Canovai A, Lardner E, Cammalleri M, Kvanta A, André H, et al. Autophagy Involvement in the Postnatal Development of the Rat Retina. Cells. 2021;10: pubmed 出版商
Goggins B, Minahan K, Sherwin S, Soh W, Pryor J, Bruce J, et al. Pharmacological HIF-1 stabilization promotes intestinal epithelial healing through regulation of α-integrin expression and function. Am J Physiol Gastrointest Liver Physiol. 2021;320:G420-G438 pubmed 出版商
Markolin P, Davidson N, Hirt C, Chabbert C, Zamboni N, Schwank G, et al. Identification of HIF-dependent alternative splicing in gastrointestinal cancers and characterization of a long, coding isoform of SLC35A3. Genomics. 2021;113:515-529 pubmed 出版商
Almeida L, Dhillon LaBrooy A, Castro C, Adossa N, Carriche G, Guderian M, et al. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis. Immunity. 2021;54:68-83.e6 pubmed 出版商
Tran C, Gold M, Garcia Batres C, Tai K, Elford A, Himmel M, et al. Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity. PLoS ONE. 2020;15:e0244366 pubmed 出版商
Pelaz S, Jaraíz Rodríguez M, Álvarez Vázquez A, Talaverón R, García Vicente L, Flores Hernández R, et al. Targeting metabolic plasticity in glioma stem cells in vitro and in vivo through specific inhibition of c-Src by TAT-Cx43266-283. EBioMedicine. 2020;62:103134 pubmed 出版商
Gomez Lado N, López Arias E, Iglesias Rey R, Díaz Platas L, Medín Aguerre S, Fernández Ferreiro A, et al. [18F]-FMISO PET/MRI Imaging Shows Ischemic Tissue around Hematoma in Intracerebral Hemorrhage. Mol Pharm. 2020;17:4667-4675 pubmed 出版商
Yang X, Zhong D, Gao W, Liao Z, Chen Y, Zhang S, et al. Conditional ablation of MAPK7 expression in chondrocytes impairs endochondral bone formation in limbs and adaptation of chondrocytes to hypoxia. Cell Biosci. 2020;10:103 pubmed 出版商
Wang N, Shi X, Khan S, Wang B, Semenza G, Prabhakar N, et al. Hypoxia-inducible factor-1 mediates pancreatic β-cell dysfunction by intermittent hypoxia. Am J Physiol Cell Physiol. 2020;319:C922-C932 pubmed 出版商
Kim C, Ding X, Allmeroth K, Biggs L, Kolenc O, L Hoest N, et al. Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle. Cell Metab. 2020;32:629-642.e8 pubmed 出版商
Samanta D, Huang T, Shah R, Yang Y, Pan F, Semenza G. BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy. Cell Rep. 2020;32:108073 pubmed 出版商
Thomas A, Samykutty A, Gomez Gutierrez J, Yin W, Egger M, McNally M, et al. Actively Targeted Nanodelivery of Echinomycin Induces Autophagy-Mediated Death in Chemoresistant Pancreatic Cancer In Vivo. Cancers (Basel). 2020;12: pubmed 出版商
Babetto E, Wong K, Beirowski B. A glycolytic shift in Schwann cells supports injured axons. Nat Neurosci. 2020;: pubmed 出版商
Hoefflin R, Harlander S, Schäfer S, Metzger P, Kuo F, Schönenberger D, et al. HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice. Nat Commun. 2020;11:4111 pubmed 出版商
Tiwari A, Tashiro K, Dixit A, Soni A, Vogel K, Hall B, et al. Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis. Gastroenterology. 2020;159:1882-1897.e5 pubmed 出版商
Ye Y, Chen Y, Sun J, Zhang H, Meng Y, Li W, et al. Hyperglycemia suppresses the regulatory effect of hypoxia-inducible factor-1α in pulmonary Aspergillus fumigatus infection. Pathog Dis. 2020;78: pubmed 出版商
Ma J, Stefanoska D, Stone L, Hildebrand M, van Donkelaar C, Zou X, et al. Hypoxic stress enhances extension and branching of dorsal root ganglion neuronal outgrowth. JOR Spine. 2020;3:e1090 pubmed 出版商
Shen Y, Wang X, Lu J, Salfenmoser M, Wirsik N, Schleussner N, et al. Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer. Cancer Cell. 2020;37:800-817.e7 pubmed 出版商
Lourenssen S, Blennerhassett M. M2 Macrophages and Phenotypic Modulation of Intestinal Smooth Muscle Cells Characterize Inflammatory Stricture Formation in Rats. Am J Pathol. 2020;190:1843-1858 pubmed 出版商
Tran M, Bibby B, Yang L, Lo F, Warren A, Shukla D, et al. Independence of HIF1a and androgen signaling pathways in prostate cancer. BMC Cancer. 2020;20:469 pubmed 出版商
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Rahtu Korpela L, Määttä J, Dimova E, Hörkkö S, Gylling H, Walkinshaw G, et al. Hypoxia-Inducible Factor Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis. Arterioscler Thromb Vasc Biol. 2016;36:608-17 pubmed 出版商
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Tando T, Sato Y, Miyamoto K, Morita M, Kobayashi T, Funayama A, et al. Hif1α is required for osteoclast activation and bone loss in male osteoporosis. Biochem Biophys Res Commun. 2016;470:391-396 pubmed 出版商
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产品信息
品牌 :
Novus
MasterCode :
NB100-479
SKU号 :
NB100-479
产品名称 :
HIF-1 alpha Antibody - BSA Free
描述 :
The HIF-1 alpha Antibody - BSA Free from NB100-479 is a nb100-479 antibody to . This antibody reacts with adaptive immunity, angiogenesis, autophagy, cancer, cardiovascular biology, cellular markers, chromatin research, cytokine research, hypoxia, hypoxia inducible factors (hif), hypoxia signaling, immunology, inflammation, innate immunity, lipid and metabolism, mtor pathway, signal transduction, transcription factors and regulators. The HIF-1 alpha Antibody - BSA Free has been validated for the following applications: Q61221.
靶标 :
HIF-1甲
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
This HIF-1 alpha antibody was developed against a fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [Uniprot# Q61221].
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠, 猪, 狗, 鱼类, 山羊, 仓鼠, 灵长类动物, 兔, 斑马鱼
理论上的分子量 :
93 kDa
基因符号 :
缺氧诱导因子1A
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Chromatin-Immunoprecipitation-NB100-479-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Chromatin-Immunoprecipitation-NB100-479-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-NB100-479-img0030.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-NB100-479-img0030.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-479-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-479-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-479-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-479-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunocytochemistry-Immunofluorescence-NB100-479-img0027.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunocytochemistry-Immunofluorescence-NB100-479-img0027.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Chromatin-Immunoprecipitation-NB100-479-img0029.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Chromatin-Immunoprecipitation-NB100-479-img0029.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0020.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Western-Blot-NB100-479-img0020.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunocytochemistry-Immunofluorescence-NB100-479-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunocytochemistry-Immunofluorescence-NB100-479-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-479-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-479-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-NB100-479-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-NB100-479-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-479-img0028.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-479-img0028.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-NB100-479-img0026.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Immunohistochemistry-NB100-479-img0026.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Simple-Western-NB100-479-img0032.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/HIF-1-alpha-Antibody-Simple-Western-NB100-479-img0032.jpg
accessionNumbers :
Q61221
应用 :
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Immunohistochemistry Whole-Mount, Chromatin Immunoprecipitation (ChIP)
美元 :
449美元
别名 :
AINT, anti-HIF-1 alpha, anti-HIF1A, ARNT interacting protein, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF1, HIF-1 alpha, HIF1A, HIF-1A, HIF-1alpha, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1 subunit alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1, PAS domain-containing protein 8, PASD8
储存 :
存放在-20C
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。