产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
NOD2 Antibody (2D9) - BSA Free
目录 :
NB100-524
规格 :
0.1 ml (also 0.025 ml)
价格 :
449美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2D9
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 24
参考文献
Thakker P, Ariana A, Hajjar S, Cai D, Rijal D, Sad S. XIAP promotes the expansion and limits the contraction of CD8 T cell response through cell extrinsic and intrinsic mechanisms respectively. PLoS Pathog. 2023;19:e1011455 pubmed 出版商
Li X, Liu S, Jin L, Ma Y, Liu T. NOD2 inhibits the proliferation of esophageal adenocarcinoma cells through autophagy. J Cancer Res Clin Oncol. 2023;149:639-652 pubmed 出版商
Huaman M, Qualls J, Jose S, Schmidt S, Moussa A, Kuhel D, et al. Mycobacterium bovis Bacille-Calmette-Guérin Infection Aggravates Atherosclerosis. Front Immunol. 2020;11:607957 pubmed 出版商
Mai E, Percopo C, Limkar A, Sek A, Ma M, Rosenberg H. Respiratory Epithelial Cells Respond to Lactobacillus plantarum but Provide No Cross-Protection against Virus-Induced Inflammation. Viruses. 2020;13: pubmed 出版商
Zhang L, Zhang B, Wei M, Xu Z, Kong W, Deng K, et al. TRIM22 inhibits endometrial cancer progression through the NOD2/NF‑κB signaling pathway and confers a favorable prognosis. Int J Oncol. 2020;56:1225-1239 pubmed 出版商
Tikka C, Manthari R, Ommati M, Niu R, Sun Z, Zhang J, et al. Immune disruption occurs through altered gut microbiome and NOD2 in arsenic induced mice: Correlation with colon cancer markers. Chemosphere. 2020;246:125791 pubmed 出版商
Valdez Miramontes C, Trejo Martínez L, Torres Juarez F, Rodríguez Carlos A, Marin Luévano S, de Haro Acosta J, et al. Nicotine modulates molecules of the innate immune response in epithelial cells and macrophages during infection with M. tuberculosis. Clin Exp Immunol. 2020;199:230-243 pubmed 出版商
Mey L, Jung M, Roos F, Blaheta R, Hegele A, Kinscherf R, et al. NOD1 and NOD2 of the innate immune system is differently expressed in human clear cell renal cell carcinoma, corresponding healthy renal tissue, its vasculature and primary isolated renal tubular epithelial cells. J Cancer Res Clin Oncol. 2019;145:1405-1416 pubmed 出版商
Lipinski S, Petersen B, Barann M, Piecyk A, Tran F, Mayr G, et al. Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2. Cold Spring Harb Mol Case Stud. 2019;5: pubmed 出版商
Singh K, Han K, Tilve S, Wu K, Geller H, Sack M. Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation. Glia. 2018;66:2427-2437 pubmed 出版商
Li J, Li B, Cheng Y, Meng Q, Wei L, Li W, et al. The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation. J Oral Pathol Med. 2019;48:87-95 pubmed 出版商
Subramanian K, Bergman P, Henriques Normark B. Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils. J Innate Immun. 2017;9:375-386 pubmed 出版商
Kapoor A, Forman M, Arav Boger R. Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication. PLoS ONE. 2014;9:e92704 pubmed 出版商
Lipinski S, Grabe N, Jacobs G, Billmann Born S, Till A, Häsler R, et al. RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition. Proc Natl Acad Sci U S A. 2012;109:21426-31 pubmed 出版商
Marischen L, Wesch D, Oberg H, Rosenstiel P, Trad A, Shomali M, et al. Functional expression of NOD2 in freshly isolated human peripheral blood ?? T cells. Scand J Immunol. 2011;74:126-34 pubmed 出版商
Billmann Born S, Till A, Arlt A, Lipinski S, Sina C, Latiano A, et al. Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC. J Immunol. 2011;186:4027-38 pubmed 出版商
von Kampen O, Lipinski S, Till A, Martin S, Nietfeld W, Lehrach H, et al. Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling. J Biol Chem. 2010;285:19921-6 pubmed 出版商
Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, et al. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med. 2010;16:90-7 pubmed 出版商
Lipinski S, Till A, Sina C, Arlt A, Grasberger H, Schreiber S, et al. DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses. J Cell Sci. 2009;122:3522-30 pubmed 出版商
Chauhan V, Sterka D, Furr S, Young A, Marriott I. NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogens. Glia. 2009;57:414-23 pubmed 出版商
Kim T, Payne U, Zhang X, Iwanaga Y, Davey M, Rosenbaum J, et al. Altered host:pathogen interactions conferred by the Blau syndrome mutation of NOD2. Rheumatol Int. 2007;27:257-62 pubmed
McDonald C, Chen F, Ollendorff V, Ogura Y, Marchetto S, Lecine P, et al. A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling. J Biol Chem. 2005;280:40301-9 pubmed
Ogura Y, Lala S, Xin W, Smith E, Dowds T, Chen F, et al. Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis. Gut. 2003;52:1591-7 pubmed
Lala S, Ogura Y, Osborne C, Hor S, Bromfield A, Davies S, et al. Crohn's disease and the NOD2 gene: a role for paneth cells. Gastroenterology. 2003;125:47-57 pubmed
图像
图像 1 :
Novus Biologicals NB100-524 图像 1
Western Blot: NOD2 Antibody (2D9) [NB100-524] - HCMV infection induces NOD2 mRNA and protein in HFFs and U373 cells. E. U373 glioma cells were infected with HCMV Towne strain and levels of NOD1, NOD2 and GAPDH mRNAs were measured by qRT-PCR at indicated time points. F. HFFs were infected with HCMV (Towne) at MOI of 1 PFU/cell and levels of NOD2 protein and B-actin were determined 48 and 72 hpi. G. HFFs were infected with HCMV (Towne) strain at MOI of 0.03 or 3 PFU/cell and levels of NOD2 protein and B-actin were determined at 48 hpi. Quantitative data represent mean values (+/-SD) of triplicate determinations from three independent experiments (*p<0.05, **p<0.01, ***p<0.001, one-way ANOVA test). Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0092704.g001) licensed under a CC-BY licence.
产品信息
品牌 :
Novus
MasterCode :
NB100-524
SKU号 :
NB100-524
产品名称 :
NOD2 Antibody (2D9) - BSA Free
描述 :
The NOD2 Antibody (2D9) - BSA Free from NB100-524 is a nb100-524 antibody to . This antibody reacts with apoptosis, autophagy, cancer, caspases, cell biology.
靶标 :
NOD2
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
2D9
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Recombinant human NOD2 protein corresponding to residues 28-301. [UniProt# Q9HC29]
抗体亚型 :
IgG1
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠
理论上的分子量 :
110 kDa
基因符号 :
NOD2
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Western-Blot-NB100-524-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Western-Blot-NB100-524-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Immunohistochemistry-Frozen-NB100-524-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Immunohistochemistry-Frozen-NB100-524-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Flow-(Intracellular)-NB100-524-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Flow-(Intracellular)-NB100-524-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)---BSA-Free-Western-Blot-NB100-524-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)---BSA-Free-Western-Blot-NB100-524-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Immunocytochemistry-Immunofluorescence-NB100-524-img0020.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Immunocytochemistry-Immunofluorescence-NB100-524-img0020.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Immunohistochemistry-NB100-524-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Immunohistochemistry-NB100-524-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Flow-Cytometry-NB100-524-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Flow-Cytometry-NB100-524-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Western-Blot-NB100-524-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Western-Blot-NB100-524-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Flow-Cytometry-NB100-524-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Flow-Cytometry-NB100-524-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Flow-Cytometry-NB100-524-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NOD2-Antibody-(2D9)-Flow-Cytometry-NB100-524-img0015.jpg
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)
美元 :
449美元
别名 :
BLAU, CARD15caspase recruitment domain protein 15, caspase recruitment domain family, member 15, Caspase recruitment domain-containing protein 15, CDACUG, CLR16.3, IBD1NLR family, CARD domain containing 2, Inflammatory bowel disease protein 1, NLRC2, NOD-like receptor C2, nucleotide-binding oligomerization domain 2, nucleotide-binding oligomerization domain containing 2, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domaincontaining 2, nucleotide-binding oligomerization domain-containing protein 2, PSORAS1NOD2B
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。