产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶8抗体
目录 :
NB100-56116
规格 :
0.05 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 37
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 3c
Jin Y, Liu Y, Xu L, Xu J, Xiong Y, Peng Y, et al. Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis. Cell Death Dis. 2022;13:512 pubmed 出版商
Zhou J, Xiang W, Zhang K, Zhao Q, Xu Z, Li Z. IL1RAP Knockdown in LPS-Stimulated Normal Human Astrocytes Suppresses LPS-Induced Reactive Astrogliosis and Promotes Neuronal Cell Proliferation. Neurochem Res. 2022;: pubmed 出版商
Lee S, Ok S, Ahn S, Sim G, Kim H, Kim M, et al. Lipid emulsion inhibits the cardiac toxicity caused by chloroquine via inhibition of reactive oxygen species production. Korean J Anesthesiol. 2022;: pubmed 出版商
Crudele A, Smeriglio A, Ingegneri M, Panera N, Bianchi M, Braghini M, et al. Hydroxytyrosol Recovers SARS-CoV-2-PLpro-Dependent Impairment of Interferon Related Genes in Polarized Human Airway, Intestinal and Liver Epithelial Cells. Antioxidants (Basel). 2022;11: pubmed 出版商
Ok S, Ahn S, Lee S, Kim H, Sim G, Park J, et al. Lipid emulsion attenuates propranolol-induced early apoptosis in rat cardiomyoblasts. Hum Exp Toxicol. 2022;41:9603271221110852 pubmed 出版商
Wu S, Hu S, Fan W, Zhang X, Wang H, Li C, et al. Nitrite exposure may induce infertility in mice. J Toxicol Pathol. 2022;35:75-82 pubmed 出版商
Chen L, Shi H, Wang X, Wang T, Wang Y, Wu Z, et al. Hepatocyte nuclear factor 4 gamma (HNF4G) is correlated with poor prognosis and promotes tumor cell growth by inhibiting caspase-dependent intrinsic apoptosis in colorectal cancer. Eur J Pharmacol. 2022;916:174727 pubmed 出版商
Kearon J, Kocherry S, Zoumboulakis D, Rivera D, Lourenssen S, Blennerhassett M. GDNF requires HIF-1α and RET activation for suppression of programmed cell death of enteric neurons by metabolic challenge. Mol Cell Neurosci. 2021;115:103655 pubmed 出版商
Li Y, Li Z, Quan Y, Cheng H, Riquelme M, Li X, et al. Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis. iScience. 2021;24:102533 pubmed 出版商
Fasolato S, Ruvoletto M, Nardo G, Rasola A, Sciacovelli M, Zanus G, et al. Low P66shc with High SerpinB3 Levels Favors Necroptosis and Better Survival in Hepatocellular Carcinoma. Biology (Basel). 2021;10: pubmed 出版商
Nishio A, Bolte F, Takeda K, Park N, Yu Z, Park H, et al. Clearance of pegylated interferon by Kupffer cells limits NK cell activation and therapy response of patients with HBV infection. Sci Transl Med. 2021;13: pubmed 出版商
Arman T, Lynch K, Goedken M, Clarke J. Sub-chronic microcystin-LR renal toxicity in rats fed a high fat/high cholesterol diet. Chemosphere. 2021;269:128773 pubmed 出版商
Ruera C, Miculán E, Perez F, Ducca G, Carasi P, Chirdo F. Sterile inflammation drives multiple programmed cell death pathways in the gut. J Leukoc Biol. 2020;: pubmed 出版商
Doganlar O, Doganlar Z, Ovali M, Guclu O, Demir U, Doğan A, et al. Melatonin regulates oxidative stress and apoptosis in fetal hearts of pinealectomised RUPP rats. Hypertens Pregnancy. 2020;39:429-443 pubmed 出版商
Tummers B, Mari L, Guy C, Heckmann B, Rodriguez D, Rühl S, et al. Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis. Immunity. 2020;52:994-1006.e8 pubmed 出版商
Ando Y, Ohuchida K, Otsubo Y, Kibe S, Takesue S, Abe T, et al. Necroptosis in pancreatic cancer promotes cancer cell migration and invasion by release of CXCL5. PLoS ONE. 2020;15:e0228015 pubmed 出版商
Riegger J, Huber Lang M, Brenner R. Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. Osteoarthritis Cartilage. 2020;28:685-697 pubmed 出版商
Popper B, Rammer M, Gasparitsch M, Singer T, Keller U, Döring Y, et al. Neonatal obstructive nephropathy induces necroptosis and necroinflammation. Sci Rep. 2019;9:18600 pubmed 出版商
Sinha S, Renganathan A, Nagendra P, Bhat V, Mathew B, Rao M. AEBP1 down regulation induced cell death pathway depends on PTEN status of glioma cells. Sci Rep. 2019;9:14577 pubmed 出版商
Riegger J, Brenner R. Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis. Cell Death Dis. 2019;10:683 pubmed 出版商
Guclu O, Doganlar O, Yuksel V, Doganlar Z. FOLFIRI-Mediated Toxicity in Human Aortic Smooth Muscle Cells and Possible Amelioration with Curcumin and Quercetin. Cardiovasc Toxicol. 2019;: pubmed 出版商
Chen S, Yang C, Sun C, Sun Y, Yang Z, Cheng S, et al. miR-21-5p Suppressed the Sensitivity of Hepatocellular Carcinoma Cells to Cisplatin by Targeting FASLG. DNA Cell Biol. 2019;38:865-873 pubmed 出版商
Xu S, Luo W, Xu X, Qian Y, Xu Z, Yu W, et al. MD2 blockade prevents oxLDL-induced renal epithelial cell injury and protects against high-fat-diet-induced kidney dysfunction. J Nutr Biochem. 2019;70:47-55 pubmed 出版商
Doganlar Z, Guclu H, Öztopuz Ö, Turkon H, Doğan A, Uzun M, et al. The Role of Melatonin in Oxidative Stress, DNA Damage, Apoptosis and Angiogenesis in Fetal Eye under Preeclampsia and Melatonin Deficiency Stress. Curr Eye Res. 2019;44:1157-1169 pubmed 出版商
Messenger Z, Hall J, Jima D, House J, Tam H, Tokarz D, et al. C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death Dis. 2018;9:1054 pubmed 出版商
Turtle J, Strain M, Reynolds J, Huang Y, Lee K, Henwood M, et al. Pain Input After Spinal Cord Injury (SCI) Undermines Long-Term Recovery and Engages Signal Pathways That Promote Cell Death. Front Syst Neurosci. 2018;12:27 pubmed 出版商
Wiberg R, Novikova L, Kingham P. Evaluation of apoptotic pathways in dorsal root ganglion neurons following peripheral nerve injury. Neuroreport. 2018;29:779-785 pubmed 出版商
Guclu H, Doganlar Z, Gürlü V, Özal A, Doğan A, Turhan M, et al. Effects of cisplatin-5-fluorouracil combination therapy on oxidative stress, DNA damage, mitochondrial apoptosis, and death receptor signalling in retinal pigment epithelium cells. Cutan Ocul Toxicol. 2018;37:291-304 pubmed 出版商
Lotti R, Shu E, Petrachi T, Marconi A, Palazzo E, Quadri M, et al. Soluble Fas Ligand Is Essential for Blister Formation in Pemphigus. Front Immunol. 2018;9:370 pubmed 出版商
Philion C, Ma D, Ruvinov I, Mansour F, Pignanelli C, Noel M, et al. Cymbopogon citratus and Camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo. Oncotarget. 2017;8:110756-110773 pubmed 出版商
Tian J, Guo S, Chen H, Peng J, Jia M, Li N, et al. Combination of Emricasan with Ponatinib Synergistically Reduces Ischemia/Reperfusion Injury in Rat Brain Through Simultaneous Prevention of Apoptosis and Necroptosis. Transl Stroke Res. 2018;9:382-392 pubmed 出版商
Li F, Wang T, Wang Z, Chen X, Liu R. Histone deacetylase inhibitor quisinostat activates caspase signaling and upregulates p53 acetylation to inhibit the proliferation of HepG2 cells. Mol Med Rep. 2017;16:6094-6101 pubmed 出版商
Zhou X, Xie L, Xia L, Bergmann F, Buchler M, Kroemer G, et al. RIP3 attenuates the pancreatic damage induced by deletion of ATG7. Cell Death Dis. 2017;8:e2918 pubmed 出版商
Liu P, Hu Y, Kang B, Tseng Y, Wu P, Liang C, et al. Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma. PLoS ONE. 2017;12:e0180620 pubmed 出版商
Hua X, Yuan X, Li Y, Chen H, Yuan J, Tanumiharjo S, et al. Desiccating stress worsens alkali burn injury by magnifying caspase-8-induced imbalance of NLRP3 and NLRP6. J Allergy Clin Immunol. 2017;140:1172-1176.e3 pubmed 出版商
Xiao J, Yao J, Jia L, Lin C, Zacks D. Protective Effect of Met12, a Small Peptide Inhibitor of Fas, on the Retinal Pigment Epithelium and Photoreceptor After Sodium Iodate Injury. Invest Ophthalmol Vis Sci. 2017;58:1801-1810 pubmed 出版商
Chi W, Hua X, Chen X, Bian F, Yuan X, Zhang L, et al. Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye. J Autoimmun. 2017;80:65-76 pubmed 出版商
图像
图像 1 :
Novus Biologicals NB100-56116 图像 1
Immunohistochemistry: Caspase-8 Antibody - (active/cleaved) [NB100-56116] - Autophagy-deficient mice showed increased activity of apoptosis and necroptosis. Reduced pancreatic Atg7 level increased the expression of Caspase-8 in 12-week-old Atg7deltapan mice. Caspase-8 quantitation and representative IF microphotographs of Atg7F/F (n=5) and Atg7deltapan (n=5) pancreatic tissue stained for DAPI (blue) and Caspase-8 (green) ( 1/1000, scale bar=50 um). Image collected and cropped by CiteAb from the following publication (http://www.nature.com/doifinder/10.1038/cddis.2017.313), licensed under a CC-BY licence.
产品信息
品牌 :
Novus
MasterCode :
NB100-56116
SKU号 :
NB100-56116
产品名称 :
胱氨酸-天冬氨酸蛋白酶8抗体
描述 :
The Caspase-8 Antibody from NB100-56116 is a nb100-56116 antibody to . This antibody reacts with apoptosis, apoptosis detections, cancer, caspases, cell biology, ubiquitin proteasome pathway. The Caspase-8 Antibody has been validated for the following applications: Q14790.
靶标 :
胱氨酸-天冬氨酸蛋白酶8
类别 :
一抗
单位尺寸 :
0.05 ml (also 0.025 ml)
缓冲液 :
Whole antisera
克隆性 :
多克隆
共轭标签 :
未共轭
宿主 :
兔
免疫原 :
Recombinant catalytically active human Caspase-8 protein.
抗体亚型 :
IgG
纯度 :
Unpurified
物种 :
Human, Mouse, Rat, Gerbil
特异性 :
Detects Caspase-8 and cleavage products
理论上的分子量 :
55.4 kDa
基因符号 :
CASP8
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Immunohistochemistry-NB100-56116-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Immunohistochemistry-NB100-56116-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Immunohistochemistry-NB100-56116-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Western-Blot-NB100-56116-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Western-Blot-NB100-56116-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Western-Blot-NB100-56116-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Immunohistochemistry-Paraffin-NB100-56116-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Immunohistochemistry-Paraffin-NB100-56116-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Immunohistochemistry-Paraffin-NB100-56116-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Immunohistochemistry-Paraffin-NB100-56116-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Immunohistochemistry-Paraffin-NB100-56116-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Caspase-8-Antibody---(active-cleaved)-Immunohistochemistry-Paraffin-NB100-56116-img0005.jpg
accessionNumbers :
Q14790
应用 :
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
美元 :
399美元
别名 :
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
储存 :
存放在-20C。 避免冻融循环
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。