产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
DNMT1 Antibody (60B1220.1) - BSA Free
目录 :
NB100-56519
规格 :
0.1 mg (also 0.025 mg)
价格 :
449美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
DyLight系列染料594
克隆名称 :
60B1220.1
反应物种 :
人类, 小鼠, 大鼠, , pigs , 家羊
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 135
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 4a
Raciti G, Spinelli R, Desiderio A, Longo M, Parrillo L, Nigro C, et al. Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity. Sci Rep. 2017;7:43526 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Wilson R, Biasutto A, Wang L, Fischer R, Baple E, Crosby A, et al. PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair (Amst). 2017;50:22-35 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Cicchini C, de Nonno V, Battistelli C, Cozzolino A, De Santis Puzzonia M, Ciafrè S, et al. Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29. Biochim Biophys Acta. 2015;1849:919-29 pubmed 出版商
  • 免疫印迹; 小鼠
Neri F, Incarnato D, Krepelova A, Rapelli S, Anselmi F, Parlato C, et al. Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals Promoter DNA Methylation Dynamics. Cell Rep. 2015;10:674-683 pubmed 出版商
  • 免疫印迹; 人类
Guo Y, Shu L, Zhang C, Su Z, Kong A. Curcumin inhibits anchorage-independent growth of HT29 human colon cancer cells by targeting epigenetic restoration of the tumor suppressor gene DLEC1. Biochem Pharmacol. 2015;94:69-78 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Poposki J, Peterson S, Welch K, Schleimer R, Hulse K, Peters A, et al. Elevated presence of myeloid dendritic cells in nasal polyps of patients with chronic rhinosinusitis. Clin Exp Allergy. 2015;45:384-93 pubmed 出版商
  • 免疫印迹; 小鼠
Swiech L, Heidenreich M, Banerjee A, Habib N, Li Y, Trombetta J, et al. In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9. Nat Biotechnol. 2015;33:102-6 pubmed 出版商
  • 免疫印迹; 小鼠
Wang L, Zhang C, Guo Y, Su Z, Yang Y, Shu L, et al. Blocking of JB6 cell transformation by tanshinone IIA: epigenetic reactivation of Nrf2 antioxidative stress pathway. AAPS J. 2014;16:1214-25 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫沉淀; 人类
Fang M, Ou J, Hutchinson L, Green M. The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype. Mol Cell. 2014;55:904-915 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Guimarães D, Antunes D, Duarte C, Ferro L, Nunes F. DNA methyltransferase immunohistochemical expression in odontogenic tumours. J Oral Pathol Med. 2015;44:59-66 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
  • 免疫印迹; 小鼠
Tajrishi M, Shin J, Hetman M, Kumar A. DNA methyltransferase 3a and mitogen-activated protein kinase signaling regulate the expression of fibroblast growth factor-inducible 14 (Fn14) during denervation-induced skeletal muscle atrophy. J Biol Chem. 2014;289:19985-99 pubmed 出版商
  • 免疫印迹; 人类
Anwar S, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A, et al. Deregulation of RB1 expression by loss of imprinting in human hepatocellular carcinoma. J Pathol. 2014;233:392-401 pubmed 出版商
  • 免疫印迹; 小鼠
Paredes Gonzalez X, Fuentes F, Su Z, Kong A. Apigenin reactivates Nrf2 anti-oxidative stress signaling in mouse skin epidermal JB6 P + cells through epigenetics modifications. AAPS J. 2014;16:727-35 pubmed 出版商
  • 免疫印迹; 人类
Calabrese R, Valentini E, Ciccarone F, Guastafierro T, Bacalini M, Ricigliano V, et al. TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells. Biochim Biophys Acta. 2014;1842:1130-6 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Serra R, Fang M, Park S, Hutchinson L, Green M. A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype. elife. 2014;3:e02313 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Teneng I, Tellez C, Picchi M, Klinge D, Yingling C, Snider A, et al. Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer. Oncogene. 2015;34:621-30 pubmed 出版商
  • 免疫印迹; 小鼠
Su Z, Zhang C, Lee J, Shu L, Wu T, Khor T, et al. Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane. Cancer Prev Res (Phila). 2014;7:319-29 pubmed 出版商
  • 免疫细胞化学; 人类
Hara E, Ono M, Eguchi T, Kubota S, Pham H, Sonoyama W, et al. miRNA-720 controls stem cell phenotype, proliferation and differentiation of human dental pulp cells. PLoS ONE. 2013;8:e83545 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Otani J, Kimura H, Sharif J, Endo T, Mishima Y, Kawakami T, et al. Cell cycle-dependent turnover of 5-hydroxymethyl cytosine in mouse embryonic stem cells. PLoS ONE. 2013;8:e82961 pubmed 出版商
  • 免疫印迹; 人类
Watson C, Collier P, Tea I, Neary R, Watson J, Robinson C, et al. Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype. Hum Mol Genet. 2014;23:2176-88 pubmed 出版商
  • 免疫细胞化学; pigs
Giraldo A, DeCourcy K, Ball S, Hylan D, Ayares D. Gene expression of Dnmt1 isoforms in porcine oocytes, embryos, and somatic cells. Cell Reprogram. 2013;15:309-21 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 免疫印迹; 小鼠
Kadriu B, Guidotti A, Chen Y, Grayson D. DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67-positive neurons in the GAD67-GFP mouse brain. J Comp Neurol. 2012;520:1951-64 pubmed 出版商
  • 免疫印迹; 人类
Yang J, Corsello T, Ma Y. Stem cell gene SALL4 suppresses transcription through recruitment of DNA methyltransferases. J Biol Chem. 2012;287:1996-2005 pubmed 出版商
  • 免疫细胞化学; 小鼠
Dhawan S, Georgia S, Tschen S, Fan G, Bhushan A. Pancreatic ? cell identity is maintained by DNA methylation-mediated repression of Arx. Dev Cell. 2011;20:419-29 pubmed 出版商
  • 免疫印迹; 小鼠
Nasonkin I, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A. Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011;519:1914-30 pubmed 出版商
  • 免疫印迹; 小鼠
Molognoni F, Cruz A, Meliso F, Morais A, Souza C, Xander P, et al. Epigenetic reprogramming as a key contributor to melanocyte malignant transformation. Epigenetics. 2011;6:450-64 pubmed
  • 免疫印迹; 家羊
Pierard V, Guiguen A, Colin L, Wijmeersch G, Vanhulle C, Van Driessche B, et al. DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcri. J Biol Chem. 2010;285:19434-49 pubmed 出版商
  • 免疫印迹; 人类
Wu Y, Alvarez M, Slamon D, Koeffler P, Vadgama J. Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. BMC Cancer. 2010;10:32 pubmed 出版商
  • 免疫印迹; 大鼠
Perisic T, Zimmermann N, Kirmeier T, Asmus M, Tuorto F, Uhr M, et al. Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes. Neuropsychopharmacology. 2010;35:792-805 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Ye Y, McDevitt M, Guo M, Zhang W, Galm O, Gore S, et al. Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies. Cancer Res. 2009;69:8482-90 pubmed 出版商
  • 免疫沉淀; 小鼠
Hwang C, Song K, Kim C, Choi H, Guo X, Law P, et al. Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor. J Cell Mol Med. 2009;13:3591-615 pubmed 出版商
  • 免疫印迹; 小鼠
Zampieri M, Passananti C, Calabrese R, Perilli M, Corbi N, De Cave F, et al. Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity. PLoS ONE. 2009;4:e4717 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Lin H, Zuo T, Lin C, Kuo C, Liyanarachchi S, Sun S, et al. Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Res. 2008;68:10257-66 pubmed 出版商
  • 免疫沉淀; 人类
O Hagan H, Mohammad H, Baylin S. Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island. PLoS Genet. 2008;4:e1000155 pubmed 出版商
  • 免疫印迹; 小鼠
Guastafierro T, Cecchinelli B, Zampieri M, Reale A, Riggio G, Sthandier O, et al. CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery. J Biol Chem. 2008;283:21873-80 pubmed 出版商
  • 免疫印迹; 人类
Xia G, Schneider Stock R, Diestel A, Habold C, Krueger S, Roessner A, et al. Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation. Biochem Biophys Res Commun. 2008;369:526-31 pubmed 出版商
  • 免疫组化; 人类
Hodge D, Cho E, Copeland T, Guszczynski T, Yang E, Seth A, et al. IL-6 enhances the nuclear translocation of DNA cytosine-5-methyltransferase 1 (DNMT1) via phosphorylation of the nuclear localization sequence by the AKT kinase. Cancer Genomics Proteomics. 2007;4:387-98 pubmed
  • 染色质免疫沉淀 ; 人类
Ji W, Yang L, Yu L, Yuan J, Hu D, Zhang W, et al. Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells. Carcinogenesis. 2008;29:1267-75 pubmed 出版商
  • 免疫沉淀; 小鼠
Gazin C, Wajapeyee N, Gobeil S, Virbasius C, Green M. An elaborate pathway required for Ras-mediated epigenetic silencing. Nature. 2007;449:1073-7 pubmed
  • 免疫印迹; 人类
Mabaera R, Greene M, Richardson C, Conine S, Kozul C, Lowrey C. Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin. Blood. 2008;111:411-20 pubmed
  • 免疫印迹; 小鼠
Park I, Sohn B, Choo J, Joe C, Seong J, Lee Y, et al. Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development. J Cell Biochem. 2005;94:585-96 pubmed
  • 免疫印迹; 人类
Suzuki M, Sunaga N, Shames D, Toyooka S, Gazdar A, Minna J. RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells. Cancer Res. 2004;64:3137-43 pubmed
  • 免疫印迹; 人类
Kimura F, Seifert H, Florl A, Santourlidis S, Steinhoff C, Swiatkowski S, et al. Decrease of DNA methyltransferase 1 expression relative to cell proliferation in transitional cell carcinoma. Int J Cancer. 2003;104:568-78 pubmed
Tang Y, Hong F, Ding S, Yang J, Zhang M, Ma Y, et al. METTL3-mediated m6A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis. Cell Rep. 2023;42:112589 pubmed 出版商
Okuno K, Pratama M, Li J, Tokunaga M, Wang X, Kinugasa Y, et al. Ginseng mediates its anticancer activity by inhibiting the expression of DNMTs and reactivating methylation-silenced genes in colorectal cancer. Carcinogenesis. 2023;44:394-403 pubmed 出版商
da C Fernandes C, da Silva R, de Almeida G, Ferreira M, de Morais P, Bezerra F, et al. Epigenetic Differences Arise in Endothelial Cells Responding to Cobalt-Chromium. J Funct Biomater. 2023;14: pubmed 出版商
Mahadevan K, McAndrews K, LeBleu V, Yang S, Lyu H, Li B, et al. Oncogenic Kras G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 + T cells dependent manner. bioRxiv. 2023;: pubmed 出版商
Subramani P, Nagarajan N, Mariaraj S, Vilwanathan R. Knockdown of sirtuin6 positively regulates acetylation of DNMT1 to inhibit NOTCH signaling pathway in non-small cell lung cancer cell lines. Cell Signal. 2023;105:110629 pubmed 出版商
Varshney R, Das S, Trahan G, Farriester J, Mullen G, Kyere Davies G, et al. Neonatal intake of Omega-3 fatty acids enhances lipid oxidation in adipocyte precursors. iScience. 2023;26:105750 pubmed 出版商
Dai Z, Liu X, Zeng H, Chen Y. Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD. Respir Res. 2022;23:356 pubmed 出版商
Sheth V, Sharma N, Kabeer S, Tikoo K. Lactobacillus rhamnosus supplementation ameliorates high fat diet-induced epigenetic alterations and prevents its intergenerational inheritance. Life Sci. 2022;311:121151 pubmed 出版商
Zhong R, Zhang F, Yang Z, Li Y, Xu Q, Lan H, et al. Epigenetic mechanism of L-type calcium channel β-subunit downregulation in short QT human induced pluripotent stem cell-derived cardiomyocytes with CACNB2 mutation. Europace. 2022;24:2028-2036 pubmed 出版商
Zeng W, Jiang H, Wang Y, Wang C, Yu B. TCF3 Induces DNMT1 Expression to Regulate Wnt Signaling Pathway in Glioma. Neurotox Res. 2022;40:721-732 pubmed 出版商
Liu X, Cui H. The palliative effects of folic acid on retinal microvessels in diabetic retinopathy via regulating the metabolism of DNA methylation and hydroxymethylation. Bioengineered. 2021;12:10766-10774 pubmed 出版商
Kawai T, Richards J, Shimada M. Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development. Commun Biol. 2021;4:1334 pubmed 出版商
Shen Y, Zhao H, Zhang L, Hu Y, Cai L, Li J, et al. The roles of DNA methylation and hydroxymethylation at short interspersed nuclear elements in the hypothalamic arcuate nucleus during puberty. Mol Ther Nucleic Acids. 2021;26:242-252 pubmed 出版商
Bruine de Bruin L, Clausen M, Slagter Menkema L, de Bock G, Langendijk J, van der Vegt B, et al. High DNMT1 Is Associated With Worse Local Control in Early-Stage Laryngeal Squamous Cell Carcinoma. Laryngoscope. 2021;: pubmed 出版商
Huang Z, Yu J, Cui W, Johnson B, Kim K, Pfeifer G. The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins. Sci Adv. 2021;7: pubmed 出版商
Zhu A, Hopkins K, Friedman R, Bernstock J, Broustas C, Lieberman H. DNMT1 and DNMT3B regulate tumorigenicity of human prostate cancer cells by controlling RAD9 expression through targeted methylation. Carcinogenesis. 2020;: pubmed 出版商
Magno Guimarães D, deLucas da Silva Almeida F, Moraes Castilho R, Eduardo Nor J, Daumas Nunes F. DNA methyltransferase expression is associated with cell proliferation in salivary mucoepidermoid carcinoma. J Oral Pathol Med. 2020;49:1053-1060 pubmed 出版商
Ebelt N, Zuniga E, Johnson B, Diamond D, Manuel E. 5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma. Front Immunol. 2020;11:538 pubmed 出版商
So J, Skrypek N, Yang H, Merchant A, Nelson G, Chen W, et al. Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization. Cancer Res. 2020;80:2612-2627 pubmed 出版商
Uribe Etxebarria V, Garcia Gallastegui P, Pérez Garrastachu M, Casado Andrés M, Irastorza I, Unda F, et al. Wnt-3a Induces Epigenetic Remodeling in Human Dental Pulp Stem Cells. Cells. 2020;9: pubmed 出版商
Li T, Garcia Gomez A, Morante Palacios O, Ciudad L, Özkaramehmet S, Van Dijck E, et al. SIRT1/2 orchestrate acquisition of DNA methylation and loss of histone H3 activating marks to prevent premature activation of inflammatory genes in macrophages. Nucleic Acids Res. 2020;48:665-681 pubmed 出版商
Sun X, Cui Y, Feng H, Liu H, Liu X. TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity. J Exp Med. 2019;216:2819-2837 pubmed 出版商
Kuo H, Wu R, Li S, Yang A, Kong A. Anthocyanin Delphinidin Prevents Neoplastic Transformation of Mouse Skin JB6 P+ Cells: Epigenetic Re-activation of Nrf2-ARE Pathway. AAPS J. 2019;21:83 pubmed 出版商
Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, et al. Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis. Int J Mol Sci. 2019;20: pubmed 出版商
Gatta E, Grayson D, Auta J, Saudagar V, Dong E, Chen Y, et al. Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1). Mol Psychiatry. 2019;: pubmed 出版商
Huang M, Chou Y, Li M, Shih T, Lin S, Chuang H, et al. Epigenetic targeting DNMT1 of pancreatic ductal adenocarcinoma using interstitial control release biodegrading polymer reduced tumor growth through hedgehog pathway inhibition. Pharmacol Res. 2019;139:50-61 pubmed 出版商
Miotto B, Marchal C, Adelmant G, Guinot N, Xie P, Marto J, et al. Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells. Nucleic Acids Res. 2018;46:4392-4404 pubmed 出版商
Meliso F, Micali D, Silva C, Sabedot T, Coetzee S, Koch A, et al. SIRT1 regulates Mxd1 during malignant melanoma progression. Oncotarget. 2017;8:114540-114553 pubmed 出版商
Yang J, Wu R, Li W, Gao L, Yang Y, Li P, et al. The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells. Mol Carcinog. 2018;57:512-521 pubmed 出版商
Li W, Su Z, Guo Y, Zhang C, Wu R, Gao L, et al. Curcumin Derivative Epigenetically Reactivates Nrf2 Antioxidative Stress Signaling in Mouse Prostate Cancer TRAMP C1 Cells. Chem Res Toxicol. 2017;: pubmed 出版商
Chu Y, Ko C, Wang S, Lin P, Wang H, Lin W, et al. Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia. Cell Death Dis. 2017;8:e3167 pubmed 出版商
Kuang H, Tang Z, Zhang C, Wang Z, Li W, Yang C, et al. Taxifolin Activates the Nrf2 Anti-Oxidative Stress Pathway in Mouse Skin Epidermal JB6 P+ Cells through Epigenetic Modifications. Int J Mol Sci. 2017;18: pubmed 出版商
Sheikh M, Malik Y, Zhu X. RA-Induced Transcriptional Silencing of Checkpoint Kinase-2 through Promoter Methylation by Dnmt3b Is Required for Neuronal Differentiation of P19 Cells. J Mol Biol. 2017;429:2463-2473 pubmed 出版商
Miozzo F, Arnould H, de Thonel A, Schang A, Sabéran Djoneidi D, Baudry A, et al. Alcohol exposure promotes DNA methyltransferase DNMT3A upregulation through reactive oxygen species-dependent mechanisms. Cell Stress Chaperones. 2018;23:115-126 pubmed 出版商
He J, Pei L, Jiang H, Yang W, Chen J, Liang H. Chemoresistance of colorectal cancer to 5-fluorouracil is associated with silencing of the BNIP3 gene through aberrant methylation. J Cancer. 2017;8:1187-1196 pubmed 出版商
Szarc vel Szic K, Declerck K, Crans R, Diddens J, Scherf D, Gerhäuser C, et al. Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A. Oncotarget. 2017;8:40434-40453 pubmed 出版商
Anwar S, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A, et al. hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma. World J Gastroenterol. 2017;23:1568-1575 pubmed 出版商
Neri F, Rapelli S, Krepelova A, Incarnato D, Parlato C, Basile G, et al. Intragenic DNA methylation prevents spurious transcription initiation. Nature. 2017;543:72-77 pubmed 出版商
Koh H, Scruggs A, Huang S. Transforming Growth Factor-β1 Increases DNA Methyltransferase 1 and 3a Expression through Distinct Post-transcriptional Mechanisms in Lung Fibroblasts. J Biol Chem. 2016;291:19287-98 pubmed 出版商
Daniel F, Alves S, Vieira D, Biz M, Daniel I, Modolo F. Immunohistochemical expression of DNA methyltransferases 1, 3a, and 3b in actinic cheilitis and lip squamous cell carcinomas. J Oral Pathol Med. 2016;45:774-779 pubmed 出版商
Li W, Pung D, Su Z, Guo Y, Zhang C, Yang A, et al. Epigenetics Reactivation of Nrf2 in Prostate TRAMP C1 Cells by Curcumin Analogue FN1. Chem Res Toxicol. 2016;29:694-703 pubmed 出版商
Hong B, Su Z, Zhang C, Yang Y, Guo Y, Li W, et al. Reserpine Inhibit the JB6 P+ Cell Transformation Through Epigenetic Reactivation of Nrf2-Mediated Anti-oxidative Stress Pathway. AAPS J. 2016;18:659-69 pubmed 出版商
Miao C, Qin D, Du C, Ye H, Shi W, Xiong Y, et al. DNMT1 activates the canonical Wnt signaling in rheumatoid arthritis model rats via a crucial functional crosstalk between miR-152 and the DNMT1, MeCP2. Int Immunopharmacol. 2015;28:344-53 pubmed 出版商
Kopparapu P, Miranda C, Fogelstrand L, Mishra K, Andersson P, Kanduri C, et al. MCPH1 maintains long-term epigenetic silencing of ANGPT2 in chronic lymphocytic leukemia. FEBS J. 2015;282:1939-52 pubmed 出版商
Huichalaf C, Micheloni S, Ferri G, Caccia R, Gabellini D. DNA methylation analysis of the macrosatellite repeat associated with FSHD muscular dystrophy at single nucleotide level. PLoS ONE. 2014;9:e115278 pubmed 出版商
Bittencourt D, Lee B, Gao L, Gerke D, Stallcup M. Role of distinct surfaces of the G9a ankyrin repeat domain in histone and DNA methylation during embryonic stem cell self-renewal and differentiation. Epigenetics Chromatin. 2014;7:27 pubmed 出版商
Fang P, Zhang D, Cheng Z, Yan C, Jiang X, Kruger W, et al. Hyperhomocysteinemia potentiates hyperglycemia-induced inflammatory monocyte differentiation and atherosclerosis. Diabetes. 2014;63:4275-90 pubmed 出版商
Chuang C, Wang W, Li C, Ko C, Chou Y, Chuu C, et al. The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer. Cell Death Dis. 2014;5:e1220 pubmed 出版商
Neidhart M, Karouzakis E, Jungel A, Gay R, Gay S. Inhibition of spermidine/spermine N1-acetyltransferase activity: a new therapeutic concept in rheumatoid arthritis. Arthritis Rheumatol. 2014;66:1723-33 pubmed 出版商
Kanduri M, Sander B, Ntoufa S, Papakonstantinou N, Sutton L, Stamatopoulos K, et al. A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma. Epigenetics. 2013;8:1280-8 pubmed 出版商
Sheikh M, Malik Y, Yu H, Lai M, Wang X, Zhu X. Epigenetic regulation of Dpp6 expression by Dnmt3b and its novel role in the inhibition of RA induced neuronal differentiation of P19 cells. PLoS ONE. 2013;8:e55826 pubmed 出版商
Anwar S, Albat C, Krech T, Hasemeier B, Schipper E, Schweitzer N, et al. Concordant hypermethylation of intergenic microRNA genes in human hepatocellular carcinoma as new diagnostic and prognostic marker. Int J Cancer. 2013;133:660-70 pubmed 出版商
Grau L, Luque Garcia J, Gonzalez Peramato P, Theodorescu D, Palou J, Fernández Gómez J, et al. A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness. PLoS ONE. 2013;8:e53328 pubmed 出版商
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产品信息
品牌 :
Novus
MasterCode :
NB100-56519
SKU号 :
NB100-56519
产品名称 :
DNMT1 Antibody (60B1220.1) - BSA Free
描述 :
The DNMT1 Antibody (60B1220.1) - BSA Free from NB100-56519 is a nb100-56519 antibody to . This antibody reacts with chromatin research, core esc like genes, epigenetics, stem cell markers, transcription factors and regulators. The DNMT1 Antibody (60B1220.1) - BSA Free has been validated for the following applications: P26358.
靶标 :
DNMT1
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.025 mg)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
60B1220.1
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
这通过免疫制备抗体a合成多肽对应于氨基酸637-650(EKDDREDKENAFKR)人的Dnmt1(GenBank登录号。 NP_001370)
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠, 猪, 牛, 羊
基因符号 :
DNMT1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Western-Blot-NB100-56519-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Western-Blot-NB100-56519-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Western-Blot-NB100-56519-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Immunocytochemistry-Immunofluorescence-NB100-56519-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Immunocytochemistry-Immunofluorescence-NB100-56519-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Immunocytochemistry-Immunofluorescence-NB100-56519-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Immunohistochemistry-Paraffin-NB100-56519-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Immunohistochemistry-Paraffin-NB100-56519-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Immunohistochemistry-Paraffin-NB100-56519-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Flow-Cytometry-NB100-56519-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Flow-Cytometry-NB100-56519-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Flow-Cytometry-NB100-56519-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Flow-Cytometry-NB100-56519-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Flow-Cytometry-NB100-56519-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Flow-Cytometry-NB100-56519-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Simple-Western-NB100-56519-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Simple-Western-NB100-56519-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Simple-Western-NB100-56519-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Immunoprecipitation-NB100-56519-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Immunoprecipitation-NB100-56519-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DNMT1-Antibody-(60B1220.1)-Immunoprecipitation-NB100-56519-img0011.jpg
accessionNumbers :
P26358
应用 :
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular), Immunohistochemistry Free-Floating, Chromatin Immunoprecipitation (ChIP), CyTOF-ready, Knockdown Validated
美元 :
449美元
别名 :
AIM, CXXC9CXXC finger protein 9, CXXC-type zinc finger protein 9, DNA (cytosine-5-)-methyltransferase 1, DNA (cytosine-5)-methyltransferase 1, DNA methyltransferase 1, DNA methyltransferase HsaI, DNA MTase HsaI, DNMT, Dnmt1, EC 2.1.1.37, FLJ16293, m.HsaI, MCMTMGC104992
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。