| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Queen J, Agarwal S, Dolores J, Stehlik C, Satchell K. Mechanisms of inflammasome activation by Vibrio cholerae secreted toxins vary with strain biotype. Infect Immun. 2015;83:2496-506 pubmed 出版商 |
| Rimessi A, Bezzerri V, Patergnani S, Marchi S, Cabrini G, Pinton P. Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis. Nat Commun. 2015;6:6201 pubmed 出版商 |
| de Rivero Vaccari J, Brand F, Adamczak S, Lee S, Perez Barcena J, Wang M, et al. Exosome-mediated inflammasome signaling after central nervous system injury. J Neurochem. 2016;136 Suppl 1:39-48 pubmed 出版商 |
| Paciello I, Silipo A, Lembo Fazio L, Curcurù L, Zumsteg A, Noël G, et al. Intracellular Shigella remodels its LPS to dampen the innate immune recognition and evade inflammasome activation. Proc Natl Acad Sci U S A. 2013;110:E4345-54 pubmed 出版商 |
| Mawhinney L, de Rivero Vaccari J, Dale G, Keane R, Bramlett H. Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats. BMC Neurosci. 2011;12:123 pubmed 出版商 |
| Landau D, Shukri N, Arazi E, Tobar A, Segev Y. Beneficiary Effects of Colchicine on Inflammation and Fibrosis in a Mouse Model of Kidney Injury. Nephron. 2023;147:693-700 pubmed 出版商 |
| Fu Y, Cao J, Wei X, Ge Y, Su Z, Yu D. Klotho alleviates contrast-induced acute kidney injury by suppressing oxidative stress, inflammation, and NF-KappaB/NLRP3-mediated pyroptosis. Int Immunopharmacol. 2023;118:110105 pubmed 出版商 |
| Sobrano Fais R, Menezes da Costa R, Carvalho Mendes A, Mestriner F, Comerma Steffensen S, Tostes R, et al. NLRP3 activation contributes to endothelin-1-induced erectile dysfunction. J Cell Mol Med. 2023;27:1-14 pubmed 出版商 |
| Missiroli S, Perrone M, Gaf xe0 R, Nicoli F, Bonora M, Morciano G, et al. PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment. Cell Death Differ. 2023;30:429-441 pubmed 出版商 |
| Xie J, Zhu C, Wan X, Zhao Z, Meng Y, Li P, et al. GSDMD-mediated NETosis promotes the development of acute respiratory distress syndrome. Eur J Immunol. 2023;53:e2250011 pubmed 出版商 |
| Luo T, Zhou X, Qin M, Lin Y, Lin J, Chen G, et al. Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation. Oxid Med Cell Longev. 2022;2022:1652244 pubmed 出版商 |
| Zhao K, Li S, Chen J, Jin Q. Inhibitory Effect of Trihydroxy Isoflavone on Neuronal Apoptosis in Natural Aging Rats. Dis Markers. 2022;2022:4688203 pubmed 出版商 |
| Zhang Z, Tan Q, Guo P, Huang S, Jia Z, Liu X, et al. NLRP3 inflammasome-mediated choroid plexus hypersecretion contributes to hydrocephalus after intraventricular hemorrhage via phosphorylated NKCC1 channels. J Neuroinflammation. 2022;19:163 pubmed 出版商 |
| Wu X, Chen Y, Liu C, Gong J, Xu X. STING Induces Liver Ischemia-Reperfusion Injury by Promoting Calcium-Dependent Caspase 1-GSDMD Processing in Macrophages. Oxid Med Cell Longev. 2022;2022:8123157 pubmed 出版商 |
| Sousa A, Vale G, Nascimento J, Awata W, Silva C, Assis V, et al. Inhibition of inducible nitric oxide synthase protects against the deleterious effects of sub-lethal sepsis and ethanol in the cardiorenal system. Can J Physiol Pharmacol. 2021;99:1324-1332 pubmed 出版商 |
| Cau S, Bruder Nascimento A, Silva M, Ramalho F, Mestriner F, Alves Lopes R, et al. Angiotensin-II activates vascular inflammasome and induces vascular damage. Vascul Pharmacol. 2021;139:106881 pubmed 出版商 |
| El Rous M, Saber S, Raafat E, Ahmed A. Dapagliflozin, an SGLT2 inhibitor, ameliorates acetic acid-induced colitis in rats by targeting NFκB/AMPK/NLRP3 axis. Inflammopharmacology. 2021;29:1169-1185 pubmed 出版商 |
| Kerr N, de Rivero Vaccari J, Weaver C, Dietrich W, Ahmed T, Keane R. Enoxaparin Attenuates Acute Lung Injury and Inflammasome Activation after Traumatic Brain Injury. J Neurotrauma. 2021;38:646-654 pubmed 出版商 |
| Lin Y, Luo T, Weng A, Huang X, Yao Y, Fu Z, et al. Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling. Front Immunol. 2020;11:580593 pubmed 出版商 |
| Bourgeois J, Kalyanasundaram G, Figueroa C, Srinivasan A, Kopec A. A semi-automated brain atlas-based analysis pipeline for c-Fos immunohistochemical data. J Neurosci Methods. 2020;:108982 pubmed 出版商 |
| Lu Q, Zhang Y, Kasetti R, Gaddipati S, Cvm N, Borchman D, et al. Heterozygous Loss of Yap1 in Mice Causes Progressive Cataracts. Invest Ophthalmol Vis Sci. 2020;61:21 pubmed 出版商 |
| Liu L, Chen M, Lin K, Xiang X, Zheng Y, Zhu S. Inhibiting Caspase-12 Mediated Inflammasome Activation protects against Oxygen-Glucose Deprivation Injury in Primary Astrocytes. Int J Med Sci. 2020;17:1936-1945 pubmed 出版商 |
| Pan H, Lin Y, Dou J, Fu Z, Yao Y, Ye S, et al. Wedelolactone facilitates Ser/Thr phosphorylation of NLRP3 dependent on PKA signalling to block inflammasome activation and pyroptosis. Cell Prolif. 2020;:e12868 pubmed 出版商 |
| Rimessi A, Pozzato C, Carparelli L, Rossi A, Ranucci S, De Fino I, et al. Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis. Sci Adv. 2020;6:eaax9093 pubmed 出版商 |
| Xie W, Ding J, Xie X, Yang X, Wu X, Chen Z, et al. Hepatitis B virus X protein promotes liver cell pyroptosis under oxidative stress through NLRP3 inflammasome activation. Inflamm Res. 2020;69:683-696 pubmed 出版商 |
| Dang S, Zhang Z, LI K, Zheng J, Qian L, Liu X, et al. Blockade of β-adrenergic signaling suppresses inflammasome and alleviates cardiac fibrosis. Ann Transl Med. 2020;8:127 pubmed 出版商 |
| Chueh T, Cheng Y, Chen K, Chien C. Thromboxane A2 Synthase and Thromboxane Receptor Deletion Reduces Ischaemia/Reperfusion-Evoked Inflammation, Apoptosis, Autophagy and Pyroptosis. Thromb Haemost. 2020;120:329-343 pubmed 出版商 |
| Madsen P, Desu H, de Rivero Vaccari J, Florimon Y, Ellman D, Keane R, et al. Oligodendrocytes modulate the immune-inflammatory response in EAE via TNFR2 signaling. Brain Behav Immun. 2020;84:132-146 pubmed 出版商 |
| Wang J, Li R, Peng Z, Hu B, Rao X, Li J. HMGB1 participates in LPS‑induced acute lung injury by activating the AIM2 inflammasome in macrophages and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways. Int J Mol Med. 2020;45:61-80 pubmed 出版商 |
| Pereira C, Carlos D, Ferreira N, Silva J, Zanotto C, Zamboni D, et al. Mitochondrial DNA Promotes NLRP3 Inflammasome Activation and Contributes to Endothelial Dysfunction and Inflammation in Type 1 Diabetes. Front Physiol. 2019;10:1557 pubmed 出版商 |
| Köse Vogel N, Stengel S, Gardey E, Kirchberger Tolstik T, Reuken P, Stallmach A, et al. Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines. Cells. 2019;9: pubmed 出版商 |
| Ferreira N, Bruder Nascimento T, Pereira C, Zanotto C, Prado D, Silva J, et al. NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus. Cells. 2019;8: pubmed 出版商 |
| Fais R, Rodrigues F, Pereira C, Mendes A, Mestriner F, Tostes R, et al. The inflammasome NLRP3 plays a dual role on mouse corpora cavernosa relaxation. Sci Rep. 2019;9:16224 pubmed 出版商 |
| Li Y, Su Y, Zhou T, Hu Z, Wei J, Wang W, et al. Activation of the NLRP3 Inflammasome Pathway by Prokineticin 2 in Testicular Macrophages of Uropathogenic Escherichia coli- Induced Orchitis. Front Immunol. 2019;10:1872 pubmed 出版商 |
| Frew J, Hawkes J, Krueger J. A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa. F1000Res. 2018;7:1923 pubmed 出版商 |
| Pronin A, Pham D, An W, Dvoriantchikova G, Reshetnikova G, Qiao J, et al. Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury. Front Mol Neurosci. 2019;12:36 pubmed 出版商 |
| Mejias N, Martinez C, Stephens M, de Rivero Vaccari J. Contribution of the inflammasome to inflammaging. J Inflamm (Lond). 2018;15:23 pubmed 出版商 |
| Kerr N, Garcia Contreras M, Abbassi S, Mejias N, Desousa B, Ricordi C, et al. Inflammasome Proteins in Serum and Serum-Derived Extracellular Vesicles as Biomarkers of Stroke. Front Mol Neurosci. 2018;11:309 pubmed 出版商 |
| Raval A, Schatz M, Bhattacharya P, d Adesky N, Rundek T, Dietrich W, et al. Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats. Int J Mol Sci. 2018;19: pubmed 出版商 |
| Furuya M, Asano T, Sumichika Y, Sato S, Kobayashi H, Watanabe H, et al. Tofacitinib inhibits granulocyte-macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophils. Arthritis Res Ther. 2018;20:196 pubmed 出版商 |
| d Adesky N, de Rivero Vaccari J, Bhattacharya P, Schatz M, Perez Pinzon M, Bramlett H, et al. Nicotine Alters Estrogen Receptor-Beta-Regulated Inflammasome Activity and Exacerbates Ischemic Brain Damage in Female Rats. Int J Mol Sci. 2018;19: pubmed 出版商 |
| Chen D, Chen Y, Chen H, Hsieh C, Gung N, Hung W, et al. Human parvovirus B19 nonstructural protein NS1 activates NLRP3 inflammasome signaling in adult‑onset Still's disease. Mol Med Rep. 2018;17:3364-3371 pubmed 出版商 |
| Fleetwood A, Lee M, Singleton W, Achuthan A, Lee M, O Brien Simpson N, et al. Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles. Front Cell Infect Microbiol. 2017;7:351 pubmed 出版商 |
| Hua X, Yuan X, Li Y, Chen H, Yuan J, Tanumiharjo S, et al. Desiccating stress worsens alkali burn injury by magnifying caspase-8-induced imbalance of NLRP3 and NLRP6. J Allergy Clin Immunol. 2017;140:1172-1176.e3 pubmed 出版商 |
| Lévesque S, Paré A, Mailhot B, Bellver Landete V, Kébir H, Lécuyer M, et al. Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice. J Exp Med. 2016;213:929-49 pubmed 出版商 |
| Lin Q, Li C, Zha Q, Xu L, Pan H, Zhao G, et al. Gossypol induces pyroptosis in mouse macrophages via a non-canonical inflammasome pathway. Toxicol Appl Pharmacol. 2016;292:56-64 pubmed 出版商 |
| Fernandez M, Miller E, Krammer F, Gopal R, Greenbaum B, Bhardwaj N. Ion efflux and influenza infection trigger NLRP3 inflammasome signaling in human dendritic cells. J Leukoc Biol. 2016;99:723-34 pubmed 出版商 |
| Melehani J, James D, Dumont A, Torres V, Duncan J. Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular. PLoS Pathog. 2015;11:e1004970 pubmed 出版商 |
| Zhang X, Ibrahim E, de Rivero Vaccari J, Lotocki G, Aballa T, Dietrich W, et al. Involvement of the inflammasome in abnormal semen quality of men with spinal cord injury. Fertil Steril. 2013;99:118-24 pubmed 出版商 |
| Taxman D, Swanson K, Broglie P, Wen H, Holley Guthrie E, Huang M, et al. Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis. J Biol Chem. 2012;287:32791-9 pubmed |
| Tomura S, de Rivero Vaccari J, Keane R, Bramlett H, Dietrich W. Effects of therapeutic hypothermia on inflammasome signaling after traumatic brain injury. J Cereb Blood Flow Metab. 2012;32:1939-47 pubmed 出版商 |
| de Rivero Vaccari J, Sawaya M, Brand F, Nusbaum B, Bauman A, Bramlett H, et al. Caspase-1 level is higher in the scalp in androgenetic alopecia. Dermatol Surg. 2012;38:1033-9 pubmed 出版商 |
| de Rivero Vaccari J, Bastien D, Yurcisin G, Pineau I, Dietrich W, De Koninck Y, et al. P2X4 receptors influence inflammasome activation after spinal cord injury. J Neurosci. 2012;32:3058-66 pubmed 出版商 |
| Nadeau S, Filali M, Zhang J, Kerr B, Rivest S, Soulet D, et al. Functional recovery after peripheral nerve injury is dependent on the pro-inflammatory cytokines IL-1? and TNF: implications for neuropathic pain. J Neurosci. 2011;31:12533-42 pubmed 出版商 |
| Taxman D, Holley Guthrie E, Huang M, Moore C, Bergstralh D, Allen I, et al. The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. J Biol Chem. 2011;286:19605-16 pubmed 出版商 |
| Atay S, Gercel Taylor C, Taylor D. Human trophoblast-derived exosomal fibronectin induces pro-inflammatory IL-1? production by macrophages. Am J Reprod Immunol. 2011;66:259-69 pubmed 出版商 |
| Rawat R, Cohen T, Ampong B, Francia D, Henriques Pons A, Hoffman E, et al. Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle. Am J Pathol. 2010;176:2891-900 pubmed 出版商 |
| Banerjee M, Datta M, Majumder P, Mukhopadhyay D, Bhattacharyya N. Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1. Nucleic Acids Res. 2010;38:878-92 pubmed 出版商 |
| Craven R, Gao X, Allen I, Gris D, Bubeck Wardenburg J, McElvania TeKippe E, et al. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS ONE. 2009;4:e7446 pubmed 出版商 |
| Duncan J, Gao X, Huang M, O Connor B, Thomas C, Willingham S, et al. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. J Immunol. 2009;182:6460-9 pubmed 出版商 |
| Hurst J, Prinz N, Lorenz M, Bauer S, Chapman J, Lackner K, et al. TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells. Immunobiology. 2009;214:683-91 pubmed 出版商 |
| Dostert C, Petrilli V, van Bruggen R, Steele C, Mossman B, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008;320:674-7 pubmed 出版商 |
| Dorfleutner A, Bryan N, Talbott S, Funya K, Rellick S, Reed J, et al. Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation. Infect Immun. 2007;75:1484-92 pubmed |
