This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Toll样受体4抗体
目录 :
NB100-56580
规格 :
0.1 mg (also 0.025 mg)
价格 :
329美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
60.11
反应物种 :
人类, 小鼠, 大鼠, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
文章摘录数: 50
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠; 1:100; 图 3
Alanazi A, Fadda L, Alhusaini A, Ahmad R, Hasan I, Mahmoud A. Liposomal Resveratrol and/or Carvedilol Attenuate Doxorubicin-Induced Cardiotoxicity by Modulating Inflammation, Oxidative Stress and S100A1 in Rats. Antioxidants (Basel). 2020;9: pubmed 出版商
Kim S, Shin M, Lee A, Seo B, Park H, Roh S. Improvement of Inflammation through Antioxidant Pathway of Gardeniae Fructus 50% EtOH Extract (GE) from Acute Reflux Esophagitis Rats. Biomed Res Int. 2020;2020:4826176 pubmed 出版商
Cho M, Lee O, Chang E, Lee S, Moon S, Lee J, et al. BIRC5 Expression is Regulated in Uterine Epithelium During the Estrous Cycle. Genes (Basel). 2020;11: pubmed 出版商
Ring A, Nguyen C, Smbatyan G, Tripathy D, Yu M, Press M, et al. CBP/β-Catenin/FOXM1 Is a Novel Therapeutic Target in Triple Negative Breast Cancer. Cancers (Basel). 2018;10: pubmed 出版商
Koh G, Kane A, Lee K, Xu Q, Wu X, Roper J, et al. Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice. Int J Cancer. 2018;: pubmed 出版商
Fenstermaker R, Figel S, Qiu J, Barone T, Dharma S, Winograd E, et al. Survivin Monoclonal Antibodies Detect Survivin Cell Surface Expression and Inhibit Tumor Growth In Vivo. Clin Cancer Res. 2018;24:2642-2652 pubmed 出版商
Gallagher S, Gunatilake D, Beaumont K, Sharp D, Tiffen J, Heinemann A, et al. HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. Int J Cancer. 2018;142:1926-1937 pubmed 出版商
Galbo P, Ciesielski M, Figel S, Maguire O, Qiu J, Wiltsie L, et al. Circulating CD9+/GFAP+/survivin+ exosomes in malignant glioma patients following survivin vaccination. Oncotarget. 2017;8:114722-114735 pubmed 出版商
Tsang T, Hsueh Y, Wei E, Lundy D, Cheng B, Chen Y, et al. Subcellular Localization of Survivin Determines Its Function in Cardiomyocytes. Theranostics. 2017;7:4577-4590 pubmed 出版商
Perconti G, Maranto C, Romancino D, Rubino P, Feo S, Bongiovanni A, et al. Pro-invasive stimuli and the interacting protein Hsp70 favour the route of alpha-enolase to the cell surface. Sci Rep. 2017;7:3841 pubmed 出版商
Bae I, Kim C, Kim J, Cheong J, Ryu J, Han M. Correlation of survivin and B-cell lymphoma 2 expression with pathological malignancy and anti-apoptotic properties of glial cell tumors. Biomed Rep. 2017;6:396-400 pubmed 出版商
Compare D, Rocco A, Coccoli P, Angrisani D, Sgamato C, Iovine B, et al. Lactobacillus casei DG and its postbiotic reduce the inflammatory mucosal response: an ex-vivo organ culture model of post-infectious irritable bowel syndrome. BMC Gastroenterol. 2017;17:53 pubmed 出版商
Dheekollu J, Malecka K, Wiedmer A, Delecluse H, Chiang A, Altieri D, et al. Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget. 2017;8:7248-7264 pubmed 出版商
Deiuliis J, Syed R, Duggineni D, Rutsky J, Rengasamy P, Zhang J, et al. Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of Macrophages. PLoS ONE. 2016;11:e0165962 pubmed 出版商
Oyama J, Shiraki A, Nishikido T, Maeda T, Komoda H, Shimizu T, et al. EGCG, a green tea catechin, attenuates the progression of heart failure induced by the heart/muscle-specific deletion of MnSOD in mice. J Cardiol. 2017;69:417-427 pubmed 出版商
Merkowsky K, Sethi R, Gill J, Singh B. Fipronil induces lung inflammation in vivo and cell death in vitro. J Occup Med Toxicol. 2016;11:10 pubmed 出版商
Pahwa R, Devaraj S, Jialal I. The effect of the accessory proteins, soluble CD14 and lipopolysaccharide-binding protein on Toll-like receptor 4 activity in human monocytes and adipocytes. Int J Obes (Lond). 2016;40:907-11 pubmed 出版商
Riehl T, Santhanam S, Foster L, Ciorba M, Stenson W. CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice. Am J Physiol Gastrointest Liver Physiol. 2015;309:G874-87 pubmed 出版商
Schöneberger H, Weiss A, Brill B, Delis N, Borghouts C, Groner B. The integration of a Stat3 specific peptide aptamer into the thioredoxin scaffold protein strongly enhances its inhibitory potency. Horm Mol Biol Clin Investig. 2011;5:1-9 pubmed 出版商
Asuncion Valenzuela M, Castro I, Gonda A, Diaz Osterman C, Jutzy J, Aspe J, et al. Cell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase. Onco Targets Ther. 2015;8:495-507 pubmed 出版商
Kusner L, Ciesielski M, Marx A, Kaminski H, Fenstermaker R. Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study. PLoS ONE. 2014;9:e102231 pubmed 出版商
Kapinas K, Kim H, Mandeville M, Martin Buley L, Croce C, Lian J, et al. microRNA-mediated survivin control of pluripotency. J Cell Physiol. 2015;230:63-70 pubmed 出版商
Rho J, Lampe P. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. J Proteome Res. 2013;12:2311-20 pubmed 出版商
Khan S, Jutzy J, Valenzuela M, Turay D, Aspe J, Ashok A, et al. Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer. PLoS ONE. 2012;7:e46737 pubmed 出版商
Hoel A, Yu P, Nguyen K, Sui X, Plescia J, Altieri D, et al. Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo. Am J Pathol. 2012;181:1151-7 pubmed 出版商
de Souza H, West G, Rebert N, de la Motte C, Drazba J, Fiocchi C. Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease. Gastroenterology. 2012;143:1017-26.e9 pubmed 出版商
Zhang H, Wang Y, Liu C, Zhang L, Xia Q, Zhang Y, et al. DNA and adenovirus tumor vaccine expressing truncated survivin generates specific immune responses and anti-tumor effects in a murine melanoma model. Cancer Immunol Immunother. 2012;61:1857-67 pubmed
Lopergolo A, Tavecchio M, Lisanti S, Ghosh J, Dohi T, Faversani A, et al. Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer. Cancer Res. 2012;72:3251-9 pubmed 出版商
Keerthivasan G, Liu H, Gump J, Dowdy S, Wickrema A, Crispino J. A novel role for survivin in erythroblast enucleation. Haematologica. 2012;97:1471-9 pubmed 出版商
Sakao K, Desineni S, Hahm E, Singh S. Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo. Prostate. 2012;72:1104-16 pubmed 出版商
Femia A, Salvianti F, Luceri C, Dolara P, Salvadori M, Pinzani P, et al. Sustained proliferation and resistance to apoptosis after a cytotoxic insult are early alterations in rat colon carcinogenesis. Int J Cancer. 2012;131:529-36 pubmed 出版商
Lechler P, Balakrishnan S, Schaumburger J, Grassel S, Baier C, Grifka J, et al. The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro. BMC Musculoskelet Disord. 2011;12:150 pubmed 出版商
Lechler P, Schaumburger J, Köck F, Balakrishnan S, Doukas S, Prantl L, et al. The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells. Calcif Tissue Int. 2011;89:211-20 pubmed 出版商
Lechler P, Renkawitz T, Campean V, Balakrishnan S, Tingart M, Grifka J, et al. The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro. BMC Cancer. 2011;11:120 pubmed 出版商
Knauer S, Heinrich U, Bier C, Habtemichael N, Docter D, Helling K, et al. An otoprotective role for the apoptosis inhibitor protein survivin. Cell Death Dis. 2010;1:e51 pubmed 出版商
Habtemichael N, W nsch D, Bier C, Tillmann S, Unruhe B, Frauenknecht K, et al. Cloning and functional characterization of the guinea pig apoptosis inhibitor protein Survivin. Gene. 2010;469:9-17 pubmed 出版商
Habtemichael N, Heinrich U, Knauer S, Schmidtmann I, Bier C, Docter D, et al. Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear. Mol Cell Neurosci. 2010;45:297-305 pubmed 出版商
Huang H, Fletcher L, Beeharry N, Daniel R, Kao G, Yen T, et al. Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint. Cancer Res. 2008;68:3724-32 pubmed 出版商
Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, et al. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation. 2008;117:1583-93 pubmed 出版商
Hino R, Uozaki H, Inoue Y, Shintani Y, Ushiku T, Sakatani T, et al. Survival advantage of EBV-associated gastric carcinoma: survivin up-regulation by viral latent membrane protein 2A. Cancer Res. 2008;68:1427-35 pubmed 出版商
Brocardo M, Lei Y, Tighe A, Taylor S, Mok M, Henderson B. Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival. J Biol Chem. 2008;283:5950-9 pubmed
Lechler P, Wu X, Bernhardt W, Campean V, Gastiger S, Hackenbeck T, et al. The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney. Am J Pathol. 2007;171:1483-98 pubmed
Ryan B, O Donovan N, Browne B, O SHEA C, Crown J, Hill A, et al. Expression of survivin and its splice variants survivin-2B and survivin-DeltaEx3 in breast cancer. Br J Cancer. 2005;92:120-4 pubmed
Ansell S, Arendt B, Grote D, Jelinek D, Novak A, Wellik L, et al. Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma. Leukemia. 2004;18:616-23 pubmed
Koyama S. Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma. Dig Dis Sci. 2003;48:2290-300 pubmed
Ku J, Kwak C, Lee H, Park H, Lee E, Lee S. Expression of survivin, a novel inhibitor of apoptosis, in superficial transitional cell carcinoma of the bladder. J Urol. 2004;171:631-5 pubmed
Xu Z, Zhao R, Ding T, Tran T, Zhang W, Pandolfi P, et al. Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression. J Biol Chem. 2004;279:1838-44 pubmed
Allen S, Florell S, Hanks A, Alexander A, Diedrich M, Altieri D, et al. Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression. Cancer Res. 2003;63:567-72 pubmed
Fortugno P, Wall N, Giodini A, O Connor D, Plescia J, Padgett K, et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci. 2002;115:575-85 pubmed
Zhu L, Fukuda S, Cordis G, Das D, Maulik N. Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning. FEBS Lett. 2001;508:369-74 pubmed
产品信息
品牌 :
Novus
master code :
NB100-56580
SKU号 :
NB100-56580.1毫克
产品名称 :
Toll样受体4抗体
描述 :
The TLR4 Antibody from Novus Biologicals is a rabbit polyclonal antibody to TLR4. This antibody reacts with human, mouse, rat, rhesus macaque. The TLR4 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
靶标 :
Toll样受体4
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.025 mg)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
This TLR4 antibody was developed against a sythetic peptide corresponding to amino acids in a range between 30-80 of mouse TLR4.
抗体亚型 :
IgG
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠, 猕猴
理论上的分子量 :
95.7 kDa
基因符号 :
Toll样受体4
catalog number base :
NB100-56580
accessionNumbers :
O00206
应用 :
免疫印迹, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡
2020美元 :
329
2021美元 :
329美元
别名 :
ARMD10, CD_antigen: CD284, CD284, CD284 antigen, EC 3.2.2.6, EC:3.2.2.6, homolog of Drosophila toll, hToll, TLR4, TLR-4, TOLL, toll like receptor 4 protein, toll-like receptor 4
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。