产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
TRAILR2/TNFRSF10B抗体
目录 :
NB100-56618
规格 :
0.1 mg (also 0.025 mg)
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
生物素
克隆名称 :
711-66
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 11
参考文献
Joung J, Kirchgatterer P, Singh A, Cho J, Nety S, Larson R, et al. CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nat Commun. 2022;13:1606 pubmed 出版商
Chen L, Hao M, Yan J, Sun L, Tai G, Cheng H, et al. Citrus-derived DHCP inhibits mitochondrial complex II to enhance TRAIL sensitivity via ROS-induced DR5 upregulation. J Biol Chem. 2021;296:100515 pubmed 出版商
Arrillaga Romany I, Odia Y, Prabhu V, Tarapore R, Merdinger K, Stogniew M, et al. Biological activity of weekly ONC201 in adult recurrent glioblastoma patients. Neuro Oncol. 2020;22:94-102 pubmed 出版商
Stein M, Malhotra J, Tarapore R, Malhotra U, Silk A, Chan N, et al. Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration. J Immunother Cancer. 2019;7:136 pubmed 出版商
Xue M, Ge Y, Yu C, Zheng Z, He X, Zhao J. Apoptosis is induced by docosahexaenoic acid in breast cancer cells via death receptor and mitochondria-mediated pathways. Mol Med Rep. 2017;16:978-982 pubmed 出版商
Shin G, Kang H, Lee A, Kim K. Hepatitis B virus-triggered autophagy targets TNFRSF10B/death receptor 5 for degradation to limit TNFSF10/TRAIL response. Autophagy. 2016;12:2451-2466 pubmed
Allen J, Crowder R, Crowder R, El Deiry W. First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent. PLoS ONE. 2015;10:e0143082 pubmed 出版商
Liu Y, Hawkins O, Vilgelm A, Pawlikowski J, Ecsedy J, Sosman J, et al. Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse Models. Clin Cancer Res. 2015;21:5338-48 pubmed 出版商
Foster K, Jane E, Premkumar D, Morales A, Pollack I. NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5. Int J Oncol. 2015;47:506-16 pubmed 出版商
Talekar M, Allen J, Dicker D, El Deiry W. ONC201 induces cell death in pediatric non-Hodgkin's lymphoma cells. Cell Cycle. 2015;14:2422-8 pubmed 出版商
Prabhu V, Allen J, Dicker D, El Deiry W. Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner. Cancer Res. 2015;75:1423-32 pubmed 出版商
产品信息
品牌 :
Novus
MasterCode :
NB100-56618
SKU号 :
NB100-56618
产品名称 :
TRAILR2/TNFRSF10B抗体
描述 :
The TRAILR2/TNFRSF10B Antibody from NB100-56618 is a nb100-56618 antibody to . This antibody reacts with apoptosis, cancer, death receptor signaling pathway.
靶标 :
TRAILR2/TNFRSF10B
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.025 mg)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
Rabbit anti-DR5 polyclonal antibody was raised against a peptide corresponding to amino acids 388 to 407 (isoform 2) of human DR5 precursor (1,2). The same sequence is found in isoform 1 at amino acids 417-436.
抗体亚型 :
IgG
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠
基因符号 :
TNFRSF10B
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAIL-R2-TNFRSF10B-Antibody-Western-Blot-NB100-56618-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAIL-R2-TNFRSF10B-Antibody-Western-Blot-NB100-56618-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAIL-R2-TNFRSF10B-Antibody-Immunohistochemistry-Paraffin-NB100-56618-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAIL-R2-TNFRSF10B-Antibody-Immunohistochemistry-Paraffin-NB100-56618-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAILR2-TNFRSF10B-Antibody-Immunohistochemistry-NB100-56618-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAILR2-TNFRSF10B-Antibody-Immunohistochemistry-NB100-56618-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAIL-R2-TNFRSF10B-Antibody-Immunocytochemistry-Immunofluorescence-NB100-56618-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAIL-R2-TNFRSF10B-Antibody-Immunocytochemistry-Immunofluorescence-NB100-56618-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAIL-R2-TNFRSF10B-Antibody-Western-Blot-NB100-56618-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/TRAIL-R2-TNFRSF10B-Antibody-Western-Blot-NB100-56618-img0003.jpg
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Cell Surface)
美元 :
399美元
别名 :
CD262, CD262 antigen, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。