产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
RelA/NFkB p65 Antibody (112A1021) - BSA Free
目录 :
NB100-56712
规格 :
0.1 mg (also 0.025 mg)
价格 :
459美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
112A1021
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 86
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 图 5c
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Pang X, Zhang J, Lopez H, Wang Y, Li W, O Neill K, et al. The carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1. J Biol Chem. 2014;289:17802-11 pubmed 出版商
Sikder K, Kesh S, Das N, Manna K, Dey S. The high antioxidative power of quercetin (aglycone flavonoid) and its glycone (rutin) avert high cholesterol diet induced hepatotoxicity and inflammation in Swiss albino mice. Food Funct. 2014;5:1294-303 pubmed 出版商
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Rao F, Cha J, Xu J, Xu R, Vandiver M, Tyagi R, et al. Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2. Mol Cell. 2014;54:119-132 pubmed 出版商
Godbersen J, Humphries L, Danilova O, Kebbekus P, Brown J, Eastman A, et al. The Nedd8-activating enzyme inhibitor MLN4924 thwarts microenvironment-driven NF-?B activation and induces apoptosis in chronic lymphocytic leukemia B cells. Clin Cancer Res. 2014;20:1576-89 pubmed 出版商
Wroblewski D, Jiang C, Croft A, Farrelly M, Zhang X, Hersey P. OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis. PLoS ONE. 2013;8:e84073 pubmed 出版商
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Dabir S, Kluge A, McColl K, Liu Y, Lam M, Halmos B, et al. PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status. Int J Cancer. 2014;134:1045-54 pubmed 出版商
Thomas R, Roberts D, Kubli D, Lee Y, Quinsay M, Owens J, et al. Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. Genes Dev. 2013;27:1365-77 pubmed 出版商
Adamski J, Price A, Dive C, Makin G. Hypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1Alpha. PLoS ONE. 2013;8:e65304 pubmed 出版商
Zinn R, Gardner E, Dobromilskaya I, Murphy S, Marchionni L, Hann C, et al. Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. Mol Cancer. 2013;12:16 pubmed 出版商
Ryder C, McColl K, Zhong F, Distelhorst C. Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk. J Biol Chem. 2012;287:27863-75 pubmed 出版商
Wong C, Anderson D, Lee E, Fairlie W, Ludlam M. Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays. Cell Death Dis. 2012;3:e288 pubmed 出版商
Tromp J, Geest C, Breij E, Elias J, van Laar J, Luijks D, et al. Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia. Clin Cancer Res. 2012;18:487-98 pubmed 出版商
Chen M, Felix K, Wang J. Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells. J Immunol. 2011;187:5684-92 pubmed 出版商
Chu R, Terrano D, Chambers T. Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration. Biochem Pharmacol. 2012;83:199-206 pubmed 出版商
Kuo K, Chen Y, Chen L, Li C, Lan Y, Chang F, et al. Involvement of phorbol-12-myristate-13-acetate-induced protein 1 in goniothalamin-induced TP53-dependent and -independent apoptosis in hepatocellular carcinoma-derived cells. Toxicol Appl Pharmacol. 2011;256:8-23 pubmed 出版商
Ishikita H. Proton-binding sites of acid-sensing ion channel 1. PLoS ONE. 2011;6:e16920 pubmed 出版商
Chen C, Huang P, Chu P, Chen M, Chou C, Wang D, et al. Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression. J Biol Chem. 2011;286:9968-76 pubmed 出版商
Poulsen R, Carr A, Hulley P. Protection against glucocorticoid-induced damage in human tenocytes by modulation of ERK, Akt, and forkhead signaling. Endocrinology. 2011;152:503-14 pubmed 出版商
Zhang L, Lopez H, George N, Liu X, Pang X, Luo X. Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways. Cell Death Differ. 2011;18:864-73 pubmed 出版商
Bodet L, Menoret E, Descamps G, Pellat Deceunynck C, Bataille R, Le Gouill S, et al. BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma. Br J Cancer. 2010;103:1808-14 pubmed 出版商
Fahham N, Sardari S, Ostad S, Vaziri B, Ghahremani M. C-terminal domain of p16(INK4a) is adequate in inducing cell cycle arrest, growth inhibition and CDK4/6 interaction similar to the full length protein in HT-1080 fibrosarcoma cells. J Cell Biochem. 2010;111:1598-606 pubmed 出版商
Tonino S, van Laar J, Van Oers M, Wang J, Eldering E, Kater A. ROS-mediated upregulation of Noxa overcomes chemoresistance in chronic lymphocytic leukemia. Oncogene. 2011;30:701-13 pubmed 出版商
Hadji A, Clybouw C, Auffredou M, Alexia C, Poalas K, Burlion A, et al. Caspase-3 triggers a TPCK-sensitive protease pathway leading to degradation of the BH3-only protein puma. Apoptosis. 2010;15:1529-39 pubmed 出版商
Zall H, Weber A, Besch R, Zantl N, Hacker G. Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1. Mol Cancer. 2010;9:164 pubmed 出版商
Sosa Seda I, Mott J, Akazawa Y, Barreyro F, Bronk S, Kaufmann S, et al. Noxa mediates hepatic stellate cell apoptosis by proteasome inhibition. Hepatol Res. 2010;40:701-10 pubmed 出版商
de Bruijn M, Raats D, Hoogwater F, van Houdt W, Cameron K, Medema J, et al. Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa. Br J Cancer. 2010;102:1254-64 pubmed 出版商
Lopez H, Zhang L, George N, Liu X, Pang X, Evans J, et al. Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage. J Biol Chem. 2010;285:15016-26 pubmed 出版商
Vilgelm A, Washington M, Wei J, Chen H, Prassolov V, Zaika A. Interactions of the p53 protein family in cellular stress response in gastrointestinal tumors. Mol Cancer Ther. 2010;9:693-705 pubmed 出版商
Streetly M, Maharaj L, Joel S, Schey S, Gribben J, Cotter F. GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death. Blood. 2010;115:3939-48 pubmed 出版商
Tahir S, Wass J, Joseph M, Devanarayan V, Hessler P, Zhang H, et al. Identification of expression signatures predictive of sensitivity to the Bcl-2 family member inhibitor ABT-263 in small cell lung carcinoma and leukemia/lymphoma cell lines. Mol Cancer Ther. 2010;9:545-57 pubmed 出版商
Ackler S, Mitten M, Foster K, Oleksijew A, Refici M, Tahir S, et al. The Bcl-2 inhibitor ABT-263 enhances the response of multiple chemotherapeutic regimens in hematologic tumors in vivo. Cancer Chemother Pharmacol. 2010;66:869-80 pubmed 出版商
Paoluzzi L, Scotto L, Marchi E, Zain J, Seshan V, O Connor O. Romidepsin and belinostat synergize the antineoplastic effect of bortezomib in mantle cell lymphoma. Clin Cancer Res. 2010;16:554-65 pubmed 出版商
High L, Szymanska B, Wilczynska Kalak U, Barber N, O Brien R, Khaw S, et al. The Bcl-2 homology domain 3 mimetic ABT-737 targets the apoptotic machinery in acute lymphoblastic leukemia resulting in synergistic in vitro and in vivo interactions with established drugs. Mol Pharmacol. 2010;77:483-94 pubmed 出版商
Cheung M, Pei J, Pei Y, Jhanwar S, Pass H, Testa J. The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival. Oncogene. 2010;29:1633-40 pubmed 出版商
Burgos J, King Lyons N, Connell T. Expression of BfrH, a putative siderophore receptor of Bordetella bronchiseptica, is regulated by iron, Fur1, and the extracellular function sigma factor EcfI. Infect Immun. 2010;78:1147-62 pubmed 出版商
Amschler K, Schön M, Pletz N, Wallbrecht K, Erpenbeck L, Schön M. NF-kappaB inhibition through proteasome inhibition or IKKbeta blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways. J Invest Dermatol. 2010;130:1073-86 pubmed 出版商
Rasheed Z, Anbazhagan A, Akhtar N, Ramamurthy S, Voss F, Haqqi T. Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytes. Arthritis Res Ther. 2009;11:R71 pubmed 出版商
Stankiewicz A, Livingstone A, Mohseni N, Mosser D. Regulation of heat-induced apoptosis by Mcl-1 degradation and its inhibition by Hsp70. Cell Death Differ. 2009;16:638-47 pubmed 出版商
Lee W, Belkhiri A, Lockhart A, Merchant N, Glaeser H, Harris E, et al. Overexpression of OATP1B3 confers apoptotic resistance in colon cancer. Cancer Res. 2008;68:10315-23 pubmed 出版商
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产品信息
品牌 :
Novus
MasterCode :
NB100-56712
SKU号 :
NB100-56712
产品名称 :
RelA/NFkB p65 Antibody (112A1021) - BSA Free
描述 :
The RelA/NFkB p65 Antibody (112A1021) - BSA Free from NB100-56712 is a nb100-56712 antibody to . This antibody reacts with apoptosis, cancer, cell biology, immune system diseases, immunology, innate immunity, neurodegeneration, neuroscience, signal transduction, transcription factors and regulators.
靶标 :
RelA/NFkB p65
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.025 mg)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
112A1021
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
This NfkB p65 antibody was raised against a synthetic peptide corresponding to amino acids 526-539 of human NF-kB (p65) protein.
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠
基因符号 :
RELA
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Western-Blot-NB100-56712-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Western-Blot-NB100-56712-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Simple-Western-NB100-56712-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Simple-Western-NB100-56712-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Western-Blot-NB100-56712-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Western-Blot-NB100-56712-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Immunohistochemistry-Paraffin-NB100-56712-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Immunohistochemistry-Paraffin-NB100-56712-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Flow-Cytometry-NB100-56712-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Flow-Cytometry-NB100-56712-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Simple-Western-NB100-56712-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/RelA-NFkB-p65-Antibody-(112A1021)-Simple-Western-NB100-56712-img0017.jpg
应用 :
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin, Flow (Intracellular), CyTOF-ready
美元 :
459美元
别名 :
anti-NF kB p65, anti-NFkB p65, anti-NF-kB p65, anti-p65, anti-RelA, anti-rela p65, MGC131774, nf kb p65, NFkB p65, NF-kB p65, NFKB3v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor ofkappa light polypeptide gene enhancer in B-cells 3 (p65)), Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3transcription factor p65, p65, p65 flow cytometry, p65 immunohistochemistry, RelA, rela p65, v-rel reticuloendotheliosis viral oncogene homolog A (avian), v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappalight polypeptide gene enhancer in B-cells 3, p65
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。