产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
AKT1[p Ser473]抗体(104A282)
目录 :
NB100-56749
规格 :
0.1 mg (also 0.025 mg)
价格 :
329美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
104A282
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Tagoug I, Sauty De Chalon A, Dumontet C. Inhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines. PLoS ONE. 2011;6:e22641 pubmed 出版商
Tacey A, Millar S, Qaradakhi T, Smith C, Hayes A, Anderson S, et al. Undercarboxylated osteocalcin has no adverse effect on endothelial function in rabbit aorta or human vascular cells. J Cell Physiol. 2020;: pubmed 出版商
Lee J, Wolfe D, Darji S, McBrayer M, Colacurcio D, Kumar A, et al. β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7. J Mol Biol. 2020;432:2633-2650 pubmed 出版商
Wiersma V, van Ziel A, Vazquez Sanchez S, Nölle A, Berenjeno Correa E, Bonaterra Pastra A, et al. Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology. Acta Neuropathol. 2019;138:943-970 pubmed 出版商
Malla S, Krueger B, Wartmann T, Sendler M, Mahajan U, Weiss F, et al. Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice. Cell Mol Life Sci. 2019;: pubmed 出版商
Sun L, Tijsma A, Mirabelli C, Baggen J, Wahedi M, Franco D, et al. Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence. Emerg Microbes Infect. 2019;8:1076-1085 pubmed 出版商
Mishra P, Paital B, Jena S, Swain S, Kumar S, Yadav M, et al. Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart. Sci Rep. 2019;9:7408 pubmed 出版商
Zhou X, Liu S, Lin X, Xu L, Mao X, Liu J, et al. Metformin Inhibit Lung Cancer Cell Growth and Invasion in Vitro as Well as Tumor Formation in Vivo Partially by Activating PP2A. Med Sci Monit. 2019;25:836-846 pubmed 出版商
Wilden A, Molina J, Feuerborn M, Boyle D, Lee S. Glutamine-dependent lysosome homeostatic changes induced by starvation and lysosome inhibition. Biochim Biophys Acta Mol Cell Res. 2018;1865:1356-1367 pubmed 出版商
Truschel S, Clayton D, Beckel J, Yabes J, Yao Y, Wolf Johnston A, et al. Age-related endolysosome dysfunction in the rat urothelium. PLoS ONE. 2018;13:e0198817 pubmed 出版商
Kondo H, Maksimova N, Otomo T, Kato H, Imai A, Asano Y, et al. Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms. Hum Mol Genet. 2017;26:173-183 pubmed 出版商
Mareninova O, Sendler M, Malla S, Yakubov I, French S, Tokhtaeva E, et al. Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis. Cell Mol Gastroenterol Hepatol. 2015;1:678-694 pubmed
Gurda B, De Guilhem De Lataillade A, Bell P, Zhu Y, Yu H, Wang P, et al. Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII. Mol Ther. 2016;24:206-216 pubmed 出版商
Meads M, Fang B, Mathews L, Gemmer J, Nong L, Rosado Lopez I, et al. Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma. Oncogene. 2016;35:2723-34 pubmed 出版商
Wedel S, Hudak L, Seibel J, Juengel E, Tsaur I, Wiesner C, et al. Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001. Life Sci. 2011;88:418-24 pubmed 出版商
Wedel S, Hudak L, Seibel J, Juengel E, Oppermann E, Haferkamp A, et al. Critical analysis of simultaneous blockage of histone deacetylase and multiple receptor tyrosine kinase in the treatment of prostate cancer. Prostate. 2011;71:722-35 pubmed 出版商
Elamin M, Shinwari Z, Hendrayani S, Al Hindi H, Al Shail E, Khafaga Y, et al. Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells. Mol Carcinog. 2010;49:302-14 pubmed 出版商
Juengel E, Engler J, Natsheh I, Jones J, Mickuckyte A, Hudak L, et al. Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells. BMC Cancer. 2009;9:161 pubmed 出版商
Luty W, Rodeberg D, Parness J, Vyas Y. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates. J Immunol. 2007;179:819-29 pubmed
Nair A, Shishodia S, Ahn K, Kunnumakkara A, Sethi G, Aggarwal B. Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion. J Immunol. 2006;177:5612-22 pubmed
产品信息
品牌 :
Novus
master code :
NB100-56749
SKU号 :
NB100-56749
产品名称 :
AKT1[p Ser473]抗体(104A282)
描述 :
The AKT1 [p Ser473] Antibody (104A282) from NB100-56749 is a nb100-56749 antibody to . This antibody reacts with angiogenesis, apoptosis, autophagy, cancer, cellular markers, growth and development, hypoxia, mtor pathway, neuronal cell markers, phospho specific, protein kinase, serine kinases, signal transduction, tyrosine kinases. The AKT1 [p Ser473] Antibody (104A282) has been validated for the following applications: P31749.
靶标 :
AKT1
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.025 mg)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
104A282
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
This AKT1 phospho Ser473 antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residues 473 of human AKT1.
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠, 兔
特异性 :
Clone 104A282 detects specifically the Ser473 phosphorylated form of AKT1
理论上的分子量 :
55.7 kDa
基因符号 :
AKT1
accessionNumbers :
P31749
应用 :
免疫印迹, 免疫组化, 免疫组化石蜡, 免疫组化冷冻
美元 :
329美元
别名 :
AKT, AKT serine/threonine kinase 1, AKT1m, CWS6, EC 2.7.11, EC 2.7.11.1, PKB, PKB alpha, PKBMGC99656, PRKBA, Protein kinase B, Protein Kinase B Alpha, Proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, RACPKB-ALPHA, Serine-Threonine Protein Kinase, v-akt murine thymoma viral oncogene homolog 1, V-Akt Murine Thymoma Viral Oncogene-Like Protein 1
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。