产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
小窝蛋白1抗体(7C8)
目录 :
NB100-615
规格 :
0.1 ml (also 0.025 ml)
价格 :
379美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
7C8
反应物种 :
人类, 小鼠, 大鼠, 家羊
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 29
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 图 2
Yokomori H, Ando W, Yoshimura K, Yamazaki H, Takahashi Y, Oda M. Increases in endothelial caveolin-1 and cavins correlate with cirrhosis progression. Micron. 2015;76:52-61 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Kallenborn Gerhardt W, Lu R, Bothe A, Thomas D, Schlaudraff J, Lorenz J, et al. Phosphodiesterase 2A localized in the spinal cord contributes to inflammatory pain processing. Anesthesiology. 2014;121:372-82 pubmed 出版商
  • 免疫印迹; 大鼠
Czeredys M, Samluk Ł, Michalec K, Tułodziecka K, Skowronek K, Nałęcz K. Caveolin-1--a novel interacting partner of organic cation/carnitine transporter (Octn2): effect of protein kinase C on this interaction in rat astrocytes. PLoS ONE. 2013;8:e82105 pubmed 出版商
  • 免疫细胞化学; 人类
Bielaszewska M, Rüter C, Kunsmann L, Greune L, Bauwens A, Zhang W, et al. Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis. PLoS Pathog. 2013;9:e1003797 pubmed 出版商
  • 免疫细胞化学; 小鼠
Charfi C, Levros L, Edouard E, Rassart E. Characterization and identification of PARM-1 as a new potential oncogene. Mol Cancer. 2013;12:84 pubmed 出版商
  • 免疫细胞化学; 人类
Grenon S, Jeanne M, Aguado Zuniga J, Conte M, Hughes Fulford M. Effects of gravitational mechanical unloading in endothelial cells: association between caveolins, inflammation and adhesion molecules. Sci Rep. 2013;3:1494 pubmed 出版商
  • 免疫印迹; 家羊
Teng R, Du J, Afolayan A, Eis A, Shi Y, Konduri G. AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2013;304:L29-42 pubmed 出版商
  • 免疫印迹; 小鼠
Catalucci D, Zhang D, DeSantiago J, Aimond F, Barbara G, Chemin J, et al. Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability. J Cell Biol. 2009;184:923-33 pubmed 出版商
Sánchez Solana B, Wang D, Qian X, Velayoudame P, Simanshu D, Acharya J, et al. The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1. Mol Cancer. 2021;20:141 pubmed 出版商
COLLINS D, Osborn M, Steer C. Differentiation of immortalized human multi-lineage progenitor to alveolar type 2-like cells: angiotensin-converting enzyme 2 expression and binding of severe acute respiratory syndrome coronavirus 2 spike and spike 1 proteins. Cytotherapy. 2021;23:1064-1073 pubmed 出版商
Kurebayashi Y, Bajimaya S, Watanabe M, Lim N, Lutz M, Dunagan M, et al. Human parainfluenza virus type 1 regulates cholesterol biosynthesis and establishes quiescent infection in human airway cells. PLoS Pathog. 2021;17:e1009908 pubmed 出版商
Anderson Baucum E, Piñeros A, Kulkarni A, Webb Robertson B, Maier B, Anderson R, et al. Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype. Cell Metab. 2021;33:1883-1893.e7 pubmed 出版商
Daneva Z, Ottolini M, Chen Y, Klimentova E, Kuppusamy M, Shah S, et al. Endothelial pannexin 1-TRPV4 channel signaling lowers pulmonary arterial pressure in mice. elife. 2021;10: pubmed 出版商
Jiang H, Wu T, Liu J, Yu X, Liu H, Bao C, et al. Caveolae/rafts protect human cerebral microvascular endothelial cells from Streptococcus suis serotype 2 α-enolase-mediated injury. Vet Microbiol. 2021;254:108981 pubmed 出版商
Srisomboon Y, Squillace D, Maniak P, Kita H, O Grady S. Fungal allergen-induced IL-33 secretion involves cholesterol-dependent, VDAC-1-mediated ATP release from the airway epithelium. J Physiol. 2020;598:1829-1845 pubmed 出版商
Savio L, de Andrade Mello P, Santos S, de Sousa J, Oliveira S, Minshall R, et al. P2X7 receptor activation increases expression of caveolin-1 and formation of macrophage lipid rafts, thereby boosting CD39 activity. J Cell Sci. 2020;133: pubmed 出版商
Kim S, Kim S, Choi Y, Yoon H, Kim A, Lee J. Retinal VEGFA maintains the ultrastructure and function of choriocapillaris by preserving the endothelial PLVAP. Biochem Biophys Res Commun. 2020;522:240-246 pubmed 出版商
de Andrade Mello P, Bian S, Savio L, Zhang H, Zhang J, Junger W, et al. Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death. Oncotarget. 2017;8:67254-67268 pubmed 出版商
Liu C, Liu T, Yu X, Gu Y. A preliminary study on the interaction between Asn-Gly-Arg (NGR)-modified multifunctional nanoparticles and vascular epithelial cells. Acta Pharm Sin B. 2017;7:361-372 pubmed 出版商
Elıyatkin N, Aktas S, Diniz G, Ozgur H, Ekin Z, Kupelioglu A. Expression of Stromal Caveolin- 1 May Be a Predictor for Aggressive Behaviour of Breast Cancer. Pathol Oncol Res. 2018;24:59-65 pubmed 出版商
Arima M, Cui D, Kimura T, Sonoda K, Ishibashi T, Matsuda S, et al. Basigin can be a therapeutic target to restore the retinal vascular barrier function in the mouse model of diabetic retinopathy. Sci Rep. 2016;6:38445 pubmed 出版商
Ayaz D, Diniz G, Kahraman D, Sayhan S, Uncel M, Karadeniz T, et al. The evaluation of the caveolin-1 and AT-rich interactive domain 1 alpha expressions in uterine smooth muscle tumors. Indian J Pathol Microbiol. 2016;59:301-4 pubmed 出版商
Li Z, Scott M, Fan E, Li Y, Liu J, Xiao G, et al. Tissue damage negatively regulates LPS-induced macrophage necroptosis. Cell Death Differ. 2016;23:1428-47 pubmed 出版商
Gabanella F, Pisani C, Borreca A, Farioli Vecchioli S, Ciotti M, Ingegnere T, et al. SMN affects membrane remodelling and anchoring of the protein synthesis machinery. J Cell Sci. 2016;129:804-16 pubmed 出版商
Boyce A, Kim M, Wicki Stordeur L, Swayne L. ATP stimulates pannexin 1 internalization to endosomal compartments. Biochem J. 2015;470:319-30 pubmed 出版商
Munjal C, Tyagi N, Lominadze D, Tyagi S. Matrix metalloproteinase-9 in homocysteine-induced intestinal microvascular endothelial paracellular and transcellular permeability. J Cell Biochem. 2012;113:1159-69 pubmed 出版商
Rudnick J, Arendt L, Klebba I, Hinds J, Iyer V, Gupta P, et al. Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells. PLoS ONE. 2011;6:e24605 pubmed 出版商
Davalos A, Fernandez Hernando C, Sowa G, Derakhshan B, Lin M, Lee J, et al. Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells. Mol Cell Proteomics. 2010;9:2109-24 pubmed 出版商
Souto R, Vallega G, Wharton J, Vinten J, Tranum Jensen J, Pilch P. Immunopurification and characterization of rat adipocyte caveolae suggest their dissociation from insulin signaling. J Biol Chem. 2003;278:18321-9 pubmed
产品信息
品牌 :
Novus
master code :
NB100-615
SKU号 :
NB100-615
产品名称 :
小窝蛋白1抗体(7C8)
描述 :
The Caveolin-1 Antibody (7C8) from NB100-615 is a nb100-615 antibody to . This antibody reacts with cancer, caveolae markers, cellular markers, cholesterol metabolism, hypoxia, lipid and metabolism, lipid droplets, signal transduction.
靶标 :
小窝蛋白1
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
三羟甲基氨基甲烷甘氨酸, 0.15 M氯化钠
克隆性 :
单克隆
克隆 :
7C8
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Intracellular membrane protein-containing vesicles (containing GLUT4) from rat adipocytes
抗体亚型 :
IgG2b
纯度 :
蛋白质A纯化
物种 :
人类, 小鼠, 大鼠, 羊
特异性 :
This is specific for caveolin alpha and beta proteins
理论上的分子量 :
23 kDa
基因符号 :
CAV1
应用 :
免疫印迹, 流式细胞仪, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡, 免疫组化冷冻, 免疫印迹
美元 :
379美元
产品细节 :
Caveolin 1 and 2 are usually both expressed and assembled into hetero-oligomers in the endoplasmic reticulum and Golgi apparatus. Caveolin 1 also interacts with lipids and lipid anchors, and may therefore function in both membrane traffic and lipid traffic. In vitro assays confirm that Caveolin 1 interacts with cholesterol, suggesting that Caveolin 1 may organize membrane cholesterol in caveolae. Caveolin 1 has high affinity to long chain unsaturated fatty acids. Additionally, Caveolin 1 may play a role in the export and import of cellular cholesterol by caveolae.
别名 :
CAV, caveolae protein, 22kD, caveolin 1, caveolae protein, 22kDa, cell growth-inhibiting protein 32, MSTP085
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。