产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
HIF-1甲抗体
目录 :
NB100-654
规格 :
0.1 ml (also 0.025 ml)
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
14F468
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, EMSA, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 52
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:200; 图 3a
Bouchard G, Therriault H, Geha S, Bujold R, Saucier C, Paquette B. Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model. Br J Cancer. 2017;116:479-488 pubmed 出版商
Liu L, Chen M, Lin K, Xiang X, Zheng Y, Zhu S. Inhibiting Caspase-12 Mediated Inflammasome Activation protects against Oxygen-Glucose Deprivation Injury in Primary Astrocytes. Int J Med Sci. 2020;17:1936-1945 pubmed 出版商
Xie W, Ding J, Xie X, Yang X, Wu X, Chen Z, et al. Hepatitis B virus X protein promotes liver cell pyroptosis under oxidative stress through NLRP3 inflammasome activation. Inflamm Res. 2020;69:683-696 pubmed 出版商
Dang S, Zhang Z, LI K, Zheng J, Qian L, Liu X, et al. Blockade of β-adrenergic signaling suppresses inflammasome and alleviates cardiac fibrosis. Ann Transl Med. 2020;8:127 pubmed 出版商
Strassheim D, Karoor V, Nijmeh H, Weston P, Lapel M, Schaack J, et al. c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells. Cells. 2020;9: pubmed 出版商
Chueh T, Cheng Y, Chen K, Chien C. Thromboxane A2 Synthase and Thromboxane Receptor Deletion Reduces Ischaemia/Reperfusion-Evoked Inflammation, Apoptosis, Autophagy and Pyroptosis. Thromb Haemost. 2020;120:329-343 pubmed 出版商
Madsen P, Desu H, de Rivero Vaccari J, Florimon Y, Ellman D, Keane R, et al. Oligodendrocytes modulate the immune-inflammatory response in EAE via TNFR2 signaling. Brain Behav Immun. 2020;84:132-146 pubmed 出版商
Wang J, Li R, Peng Z, Hu B, Rao X, Li J. HMGB1 participates in LPS‑induced acute lung injury by activating the AIM2 inflammasome in macrophages and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways. Int J Mol Med. 2020;45:61-80 pubmed 出版商
Pereira C, Carlos D, Ferreira N, Silva J, Zanotto C, Zamboni D, et al. Mitochondrial DNA Promotes NLRP3 Inflammasome Activation and Contributes to Endothelial Dysfunction and Inflammation in Type 1 Diabetes. Front Physiol. 2019;10:1557 pubmed 出版商
Gericke A, Mann C, Zadeh J, Musayeva A, Wolff I, Wang M, et al. Elevated Intraocular Pressure Causes Abnormal Reactivity of Mouse Retinal Arterioles. Oxid Med Cell Longev. 2019;2019:9736047 pubmed 出版商
Köse Vogel N, Stengel S, Gardey E, Kirchberger Tolstik T, Reuken P, Stallmach A, et al. Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines. Cells. 2019;9: pubmed 出版商
Ferreira N, Bruder Nascimento T, Pereira C, Zanotto C, Prado D, Silva J, et al. NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus. Cells. 2019;8: pubmed 出版商
Fais R, Rodrigues F, Pereira C, Mendes A, Mestriner F, Tostes R, et al. The inflammasome NLRP3 plays a dual role on mouse corpora cavernosa relaxation. Sci Rep. 2019;9:16224 pubmed 出版商
Li Y, Su Y, Zhou T, Hu Z, Wei J, Wang W, et al. Activation of the NLRP3 Inflammasome Pathway by Prokineticin 2 in Testicular Macrophages of Uropathogenic Escherichia coli- Induced Orchitis. Front Immunol. 2019;10:1872 pubmed 出版商
Zadeh J, Ruemmler R, Hartmann E, Ziebart A, Ludwig M, Patzak A, et al. Responses of retinal arterioles and ciliary arteries in pigs with acute respiratory distress syndrome (ARDS). Exp Eye Res. 2019;184:152-161 pubmed 出版商
Pronin A, Pham D, An W, Dvoriantchikova G, Reshetnikova G, Qiao J, et al. Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury. Front Mol Neurosci. 2019;12:36 pubmed 出版商
Frew J, Hawkes J, Krueger J. A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa. F1000Res. 2018;7:1923 pubmed 出版商
Mejias N, Martinez C, Stephens M, de Rivero Vaccari J. Contribution of the inflammasome to inflammaging. J Inflamm (Lond). 2018;15:23 pubmed 出版商
Serganova I, Cohen I, Vemuri K, Shindo M, Maeda M, Mane M, et al. LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response. PLoS ONE. 2018;13:e0203965 pubmed 出版商
Kerr N, Garcia Contreras M, Abbassi S, Mejias N, Desousa B, Ricordi C, et al. Inflammasome Proteins in Serum and Serum-Derived Extracellular Vesicles as Biomarkers of Stroke. Front Mol Neurosci. 2018;11:309 pubmed 出版商
Raval A, Schatz M, Bhattacharya P, d Adesky N, Rundek T, Dietrich W, et al. Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats. Int J Mol Sci. 2018;19: pubmed 出版商
Furuya M, Asano T, Sumichika Y, Sato S, Kobayashi H, Watanabe H, et al. Tofacitinib inhibits granulocyte-macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophils. Arthritis Res Ther. 2018;20:196 pubmed 出版商
d Adesky N, de Rivero Vaccari J, Bhattacharya P, Schatz M, Perez Pinzon M, Bramlett H, et al. Nicotine Alters Estrogen Receptor-Beta-Regulated Inflammasome Activity and Exacerbates Ischemic Brain Damage in Female Rats. Int J Mol Sci. 2018;19: pubmed 出版商
Chen D, Chen Y, Chen H, Hsieh C, Gung N, Hung W, et al. Human parvovirus B19 nonstructural protein NS1 activates NLRP3 inflammasome signaling in adult‑onset Still's disease. Mol Med Rep. 2018;17:3364-3371 pubmed 出版商
Fleetwood A, Lee M, Singleton W, Achuthan A, Lee M, O Brien Simpson N, et al. Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles. Front Cell Infect Microbiol. 2017;7:351 pubmed 出版商
Pan H, Lin Y, Dou J, Fu Z, Yao Y, Ye S, et al. Wedelolactone facilitates Ser/Thr phosphorylation of NLRP3 dependent on PKA signalling to block inflammasome activation and pyroptosis. Cell Prolif. 2020;:e12868 pubmed 出版商
Knudsen E, Balaji U, Freinkman E, McCue P, Witkiewicz A. Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential. Oncotarget. 2016;7:78396-78411 pubmed 出版商
Lévesque S, Paré A, Mailhot B, Bellver Landete V, Kébir H, Lécuyer M, et al. Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice. J Exp Med. 2016;213:929-49 pubmed 出版商
Lin Q, Li C, Zha Q, Xu L, Pan H, Zhao G, et al. Gossypol induces pyroptosis in mouse macrophages via a non-canonical inflammasome pathway. Toxicol Appl Pharmacol. 2016;292:56-64 pubmed 出版商
De Bruycker S, Vangestel C, Van den Wyngaert T, Wyffels L, Wouters A, Pauwels P, et al. Baseline [(18)F]FMISO μPET as a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model. Mol Imaging Biol. 2016;18:606-16 pubmed 出版商
Fernandez M, Miller E, Krammer F, Gopal R, Greenbaum B, Bhardwaj N. Ion efflux and influenza infection trigger NLRP3 inflammasome signaling in human dendritic cells. J Leukoc Biol. 2016;99:723-34 pubmed 出版商
Melehani J, James D, Dumont A, Torres V, Duncan J. Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular. PLoS Pathog. 2015;11:e1004970 pubmed 出版商
Queen J, Agarwal S, Dolores J, Stehlik C, Satchell K. Mechanisms of inflammasome activation by Vibrio cholerae secreted toxins vary with strain biotype. Infect Immun. 2015;83:2496-506 pubmed 出版商
Rimessi A, Bezzerri V, Patergnani S, Marchi S, Cabrini G, Pinton P. Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis. Nat Commun. 2015;6:6201 pubmed 出版商
de Rivero Vaccari J, Brand F, Adamczak S, Lee S, Perez Barcena J, Wang M, et al. Exosome-mediated inflammasome signaling after central nervous system injury. J Neurochem. 2016;136 Suppl 1:39-48 pubmed 出版商
Paciello I, Silipo A, Lembo Fazio L, Curcurù L, Zumsteg A, Noël G, et al. Intracellular Shigella remodels its LPS to dampen the innate immune recognition and evade inflammasome activation. Proc Natl Acad Sci U S A. 2013;110:E4345-54 pubmed 出版商
Zhang X, Ibrahim E, de Rivero Vaccari J, Lotocki G, Aballa T, Dietrich W, et al. Involvement of the inflammasome in abnormal semen quality of men with spinal cord injury. Fertil Steril. 2013;99:118-24 pubmed 出版商
Taxman D, Swanson K, Broglie P, Wen H, Holley Guthrie E, Huang M, et al. Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis. J Biol Chem. 2012;287:32791-9 pubmed
Tomura S, de Rivero Vaccari J, Keane R, Bramlett H, Dietrich W. Effects of therapeutic hypothermia on inflammasome signaling after traumatic brain injury. J Cereb Blood Flow Metab. 2012;32:1939-47 pubmed 出版商
de Rivero Vaccari J, Sawaya M, Brand F, Nusbaum B, Bauman A, Bramlett H, et al. Caspase-1 level is higher in the scalp in androgenetic alopecia. Dermatol Surg. 2012;38:1033-9 pubmed 出版商
de Rivero Vaccari J, Bastien D, Yurcisin G, Pineau I, Dietrich W, De Koninck Y, et al. P2X4 receptors influence inflammasome activation after spinal cord injury. J Neurosci. 2012;32:3058-66 pubmed 出版商
Mawhinney L, de Rivero Vaccari J, Dale G, Keane R, Bramlett H. Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats. BMC Neurosci. 2011;12:123 pubmed 出版商
Nadeau S, Filali M, Zhang J, Kerr B, Rivest S, Soulet D, et al. Functional recovery after peripheral nerve injury is dependent on the pro-inflammatory cytokines IL-1? and TNF: implications for neuropathic pain. J Neurosci. 2011;31:12533-42 pubmed 出版商
Taxman D, Holley Guthrie E, Huang M, Moore C, Bergstralh D, Allen I, et al. The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. J Biol Chem. 2011;286:19605-16 pubmed 出版商
Atay S, Gercel Taylor C, Taylor D. Human trophoblast-derived exosomal fibronectin induces pro-inflammatory IL-1? production by macrophages. Am J Reprod Immunol. 2011;66:259-69 pubmed 出版商
Rawat R, Cohen T, Ampong B, Francia D, Henriques Pons A, Hoffman E, et al. Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle. Am J Pathol. 2010;176:2891-900 pubmed 出版商
Banerjee M, Datta M, Majumder P, Mukhopadhyay D, Bhattacharyya N. Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1. Nucleic Acids Res. 2010;38:878-92 pubmed 出版商
Craven R, Gao X, Allen I, Gris D, Bubeck Wardenburg J, McElvania TeKippe E, et al. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS ONE. 2009;4:e7446 pubmed 出版商
Duncan J, Gao X, Huang M, O Connor B, Thomas C, Willingham S, et al. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. J Immunol. 2009;182:6460-9 pubmed 出版商
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Dostert C, Petrilli V, van Bruggen R, Steele C, Mossman B, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008;320:674-7 pubmed 出版商
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产品信息
品牌 :
Novus
SKU号 :
NB100-654
产品名称 :
HIF-1甲抗体
单位尺寸 :
0.1 ml (also 0.025 ml)
描述 :
The HIF-1 alpha Antibody from Novus is a rabbit polyclonal antibody to HIF-1 alpha. This antibody reacts with human, mouse, rat, porcine. The HIF-1 alpha Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Gel Super Shift Assays.
靶标 :
HIF-1甲
类别 :
一抗
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
This HIF-1 alpha Antibody was developed against a fusion protein containing amino acids 432 - 528 of human HIF-1 alpha [Uniprot# Q16665].
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠, 猪
理论上的分子量 :
93 kDa
基因符号 :
缺氧诱导因子1A
catalog number base :
NB100-654
应用 :
Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Gel Super Shift Assays
美元 :
299美元
applications abr :
WB, Simple Western, IHC, ICC/IF, IHC-P, IHC-Fr, GS
别名 :
AINT, anti-HIF-1 alpha, anti-HIF1A, ARNT interacting protein, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF1, HIF-1 alpha, HIF1A, HIF-1A, HIF-1alpha, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1 subunit alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1, PAS domain-containing protein 8, PASD8
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。