This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
CD68/SR-D1抗体(KP1)
目录 :
NB100-683
规格 :
0.025毫克
价格 :
179美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
Alexa Fluor系列荧光染料532
克隆名称 :
KP1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 52
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 图 s7
Xiong Y, Neifert S, Karuppagounder S, Liu Q, Stankowski J, Lee B, et al. Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice. Proc Natl Acad Sci U S A. 2018;115:1635-1640 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:800
Brocks T, Fedorchenko O, Schliermann N, Stein A, Moll U, Seegobin S, et al. Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen-presenting cells in skin. FASEB J. 2017;31:526-543 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:1000; 图 s1
Miao H, Ou J, Peng Y, Zhang X, Chen Y, Hao L, et al. Macrophage ABHD5 promotes colorectal cancer growth by suppressing spermidine production by SRM. Nat Commun. 2016;7:11716 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Pandurangan A, Ismail S, Saadatdoust Z, Esa N. Allicin Alleviates Dextran Sodium Sulfate- (DSS-) Induced Ulcerative Colitis in BALB/c Mice. Oxid Med Cell Longev. 2015;2015:605208 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
Lin F, Hsiao F, Huang C, Shih C, Tsao N, Tsai C, et al. Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats. PLoS ONE. 2014;9:e102450 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Joshi Barr S, Bett C, Chiang W, Trejo M, Goebel H, Sikorska B, et al. De novo prion aggregates trigger autophagy in skeletal muscle. J Virol. 2014;88:2071-82 pubmed 出版商
  • 免疫组化; 人类
Herwig M, Bergstrom C, Wells J, Höller T, Grossniklaus H. M2/M1 ratio of tumor associated macrophages and PPAR-gamma expression in uveal melanomas with class 1 and class 2 molecular profiles. Exp Eye Res. 2013;107:52-8 pubmed 出版商
  • 免疫细胞化学; 人类
Spigoni V, Picconi A, Cito M, Ridolfi V, Bonomini S, Casali C, et al. Pioglitazone improves in vitro viability and function of endothelial progenitor cells from individuals with impaired glucose tolerance. PLoS ONE. 2012;7:e48283 pubmed 出版商
  • 免疫组化; 小鼠
Chan C, Cheng L, Lin C, Huang Y, Lin H, Lee F. The protective role of natural phytoalexin resveratrol on inflammation, fibrosis and regeneration in cholestatic liver injury. Mol Nutr Food Res. 2011;55:1841-9 pubmed 出版商
  • 免疫组化; 小鼠
Avouac J, Fürnrohr B, Tomcik M, Palumbo K, Zerr P, Horn A, et al. Inactivation of the transcription factor STAT-4 prevents inflammation-driven fibrosis in animal models of systemic sclerosis. Arthritis Rheum. 2011;63:800-9 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫组化; 人类
Thenappan T, Goel A, Marsboom G, Fang Y, Toth P, Zhang H, et al. A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion. Am J Respir Crit Care Med. 2011;183:1080-91 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Sun I, Eun D, Na J, Lee S, Kim I, Youn I, et al. Heparin-coated gold nanoparticles for liver-specific CT imaging. Chemistry. 2009;15:13341-7 pubmed 出版商
  • 流式细胞仪; 人类
  • 免疫组化; 人类
  • 免疫印迹; 人类
Gottfried E, Kunz Schughart L, Weber A, Rehli M, Peuker A, Muller A, et al. Expression of CD68 in non-myeloid cell types. Scand J Immunol. 2008;67:453-63 pubmed 出版商
  • 免疫组化; 人类
Canioni D, Salles G, Mounier N, Brousse N, Keuppens M, Morchhauser F, et al. High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELA-GOELAMS FL-2000 trial. J Clin Oncol. 2008;26:440-6 pubmed
  • 免疫组化; 人类
Lau S, Chu P, Weiss L. CD163: a specific marker of macrophages in paraffin-embedded tissue samples. Am J Clin Pathol. 2004;122:794-801 pubmed
  • 免疫细胞化学; 人类
King B, Crisi G, Tsai S, Haffty B, Phillips R, Rimm D. Immunocytochemical analysis of breast cells obtained by ductal lavage. Cancer. 2002;96:244-9 pubmed
  • 免疫组化; 人类
Chang C, Eshoa C, Kampalath B, Shidham V, Perkins S. Immunophenotypic profile of myeloid cells in granulocytic sarcoma by immunohistochemistry. Correlation with blast differentiation in bone marrow. Am J Clin Pathol. 2000;114:807-11 pubmed
  • 免疫组化; 人类
Mallat Z, Heymes C, Ohan J, Faggin E, Leseche G, Tedgui A. Expression of interleukin-10 in advanced human atherosclerotic plaques: relation to inducible nitric oxide synthase expression and cell death. Arterioscler Thromb Vasc Biol. 1999;19:611-6 pubmed
  • 免疫组化; 人类
Gravallese E, Harada Y, Wang J, Gorn A, Thornhill T, Goldring S. Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis. Am J Pathol. 1998;152:943-51 pubmed
  • 流式细胞仪; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Ramprasad M, Terpstra V, Kondratenko N, Quehenberger O, Steinberg D. Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc Natl Acad Sci U S A. 1996;93:14833-8 pubmed
  • 免疫组化; 人类
Sugiyama M, Tsukazaki T, Yonekura A, Matsuzaki S, Yamashita S, Iwasaki K. Localisation of apoptosis and expression of apoptosis related proteins in the synovium of patients with rheumatoid arthritis. Ann Rheum Dis. 1996;55:442-9 pubmed
  • 免疫组化; 人类
Rugtveit J, Brandtzaeg P, Halstensen T, Fausa O, Scott H. Increased macrophage subset in inflammatory bowel disease: apparent recruitment from peripheral blood monocytes. Gut. 1994;35:669-74 pubmed
Jaén R, Fernandez Velasco M, Terrón V, Sánchez García S, Zaragoza C, Canales Bueno N, et al. BML-111 treatment prevents cardiac apoptosis and oxidative stress in a mouse model of autoimmune myocarditis. FASEB J. 2020;: pubmed 出版商
Chen W, Lin C, Kuo S, Liu S, Lu Y, Chen Y, et al. Resistin Enhances VCAM-1 Expression and Monocyte Adhesion in Human Osteoarthritis Synovial Fibroblasts by Inhibiting MiR-381 Expression through the PKC, p38, and JNK Signaling Pathways. Cells. 2020;9: pubmed 出版商
Wang M, Li H, Wang Y, Hao Y, Huang Y, Wang X, et al. Anti-Rheumatic Properties of Gentiopicroside Are Associated With Suppression of ROS-NF-κB-NLRP3 Axis in Fibroblast-Like Synoviocytes and NF-κB Pathway in Adjuvant-Induced Arthritis. Front Pharmacol. 2020;11:515 pubmed 出版商
Schoenenberger A, Tempfer H, Lehner C, Egloff J, Mauracher M, Bird A, et al. Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo. Biomaterials. 2020;249:120034 pubmed 出版商
Liu Y, Li M, Wei C, Tang L, Sheng Y, Liu Y, et al. TSP1-CD47-SIRPα signaling facilitates the development of endometriosis by mediating the survival of ectopic endometrium. Am J Reprod Immunol. 2020;83:e13236 pubmed 出版商
McCloskey C, Cook D, Kelly B, Azzi F, Allen C, Forsyth A, et al. Metformin Abrogates Age-Associated Ovarian Fibrosis. Clin Cancer Res. 2020;26:632-642 pubmed 出版商
Liu X, Chen J, Zhang B, Liu G, Zhao H, Hu Q. KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway. Cell Signal. 2019;64:109415 pubmed 出版商
Wu Y, Qin Y, Liu Y, Zhu L, Zhao X, Liu Y, et al. Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation. EBioMedicine. 2019;47:329-340 pubmed 出版商
Liu W, Kämpfe Nordström C, Danckwardt Lillieström N, Rask Andersen H. Human Inner Ear Immune Activity: A Super-Resolution Immunohistochemistry Study. Front Neurol. 2019;10:728 pubmed 出版商
Ding J, Yin T, Yan N, Cheng Y, Yang J. FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage. Int J Mol Med. 2019;43:2376-2386 pubmed 出版商
Triulzi T, Forte L, Regondi V, Di Modica M, Ghirelli C, Carcangiu M, et al. HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy. Oncoimmunology. 2019;8:e1512942 pubmed 出版商
Kämpfe Nordström C, Danckwardt Lillieström N, Laurell G, Liu W, Rask Andersen H. The Human Endolymphatic Sac and Inner Ear Immunity: Macrophage Interaction and Molecular Expression. Front Immunol. 2018;9:3181 pubmed 出版商
Triulzi T, Regondi V, De Cecco L, Cappelletti M, Di Modica M, Paolini B, et al. Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit. Br J Cancer. 2018;119:1487-1494 pubmed 出版商
van Rooijen J, Qiu S, Timmer Bosscha H, van der Vegt B, Boers J, Schröder C, et al. Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2-positive breast cancer. Eur J Cancer. 2018;103:52-60 pubmed 出版商
Li D, Wang C, Li Z, Wang H, He J, Zhu J, et al. Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts. Cell Death Dis. 2018;9:840 pubmed 出版商
Xiang W, Shi R, Kang X, Zhang X, Chen P, Zhang L, et al. Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression. Nat Commun. 2018;9:2574 pubmed 出版商
Ao J, Zhu X, Chai Z, Cai H, Zhang Y, Zhang K, et al. Colony-Stimulating Factor 1 Receptor Blockade Inhibits Tumor Growth by Altering the Polarization of Tumor-Associated Macrophages in Hepatocellular Carcinoma. Mol Cancer Ther. 2017;16:1544-1554 pubmed 出版商
Liu X, Guo X, Li J, Wu M, Zhan X. Interferon-? Aggravated L-Arginine-Induced Acute Pancreatitis in Sprague-Dawley Rats and Its Possible Mechanism: Trypsinogen Activation and Autophagy Up-regulation. Pancreas. 2017;46:619-625 pubmed 出版商
Lhotak S, Gyulay G, Cutz J, Al Hashimi A, Trigatti B, Richards C, et al. Characterization of Proliferating Lesion-Resident Cells During All Stages of Atherosclerotic Growth. J Am Heart Assoc. 2016;5: pubmed 出版商
Feng X, Weng D, Zhou F, Owen Y, Qin H, Zhao J, et al. Activation of PPAR? by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage Polarization. EBioMedicine. 2016;9:61-76 pubmed 出版商
Koh M, Gagea M, Sargis T, Lemos R, Grandjean G, Charbono A, et al. A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice. Hepatology. 2016;63:1576-91 pubmed 出版商
Della Puppa A, Persano L, Masi G, Rampazzo E, Sinigaglia A, Pistollato F, et al. MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients?. J Neurooncol. 2012;106:33-41 pubmed 出版商
Petrovichev N, Chistyakova O, Smirnov A, Poltoranina V, Rudinskaya T. Antimacrophage monoclonal antibody D11 in the diagnosis of tumors of histiocytic origin. Acta Cytol. 1997;41:357-63 pubmed
Tupitsyn N, Frenkel M, Rudinskaya T, Poltoranina V, Sholokhova E, Lebedeva N, et al. Reactivity of anti-macrophage monoclonal antibody D11 in human leukemia and malignant lymphoma. Int J Cancer. 1996;68:160-3 pubmed
Petrovichev N, Chistiakova O, Smirnov A, Rudinskaia T, Poltoranina V. [Anti-macrophage monoclonal antibody D-11 in the diagnosis of histiocytic tumors]. Arkh Patol. 1995;57:25-30 pubmed
Warnke R, Pulford K, Pallesen G, Ralfkiaer E, Brown D, Gatter K, et al. Diagnosis of myelomonocytic and macrophage neoplasms in routinely processed tissue biopsies with monoclonal antibody KP1. Am J Pathol. 1989;135:1089-95 pubmed
Pulford K, Rigney E, Micklem K, Jones M, Stross W, Gatter K, et al. KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections. J Clin Pathol. 1989;42:414-21 pubmed
Horny H, Schaumburg Lever G, Bolz S, Geerts M, Kaiserling E. Use of monoclonal antibody KP1 for identifying normal and neoplastic human mast cells. J Clin Pathol. 1990;43:719-22 pubmed
Facchetti F, Bertalot G, Grigolato P. KP1 (CD 68) staining of malignant melanomas. Histopathology. 1991;19:141-5 pubmed
Saito N, Pulford K, Breton Gorius J, Masse J, Mason D, Cramer E. Ultrastructural localization of the CD68 macrophage-associated antigen in human blood neutrophils and monocytes. Am J Pathol. 1991;139:1053-9 pubmed
产品信息
品牌 :
Novus
master code :
NB100-683
SKU号 :
NB100-683.025毫克
产品名称 :
CD68/SR-D1抗体(KP1)
描述 :
The CD68/SR-D1 Antibody (KP1) from Novus Biologicals is a mouse monoclonal antibody to CD68/SR-D1. This antibody reacts with human, mouse, rat. The CD68/SR-D1 Antibody (KP1) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Electron Microscopy.
靶标 :
CD68/SR-D1
类别 :
一抗
单位尺寸 :
0.025毫克
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
KP1
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
亚细胞组分 人的肺泡巨噬细胞
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠
特异性 :
This is specific to macrophages in a wide variety of human tissues. It reacts with myeloid precursors and peripheral blood granulocytes. It also stains a cell population known as Plasmacytoid T cells.
基因符号 :
CD68
catalog number base :
NB100-683
accessionNumbers :
P34810
应用 :
免疫印迹, 流式细胞仪, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡, 免疫组化冷冻, 电子显微镜
2020美元 :
179
2021美元 :
179美元
别名 :
CD_antigen: CD68, CD68, CD68 antigen, CD68 molecule, DKFZp686M18236, GP110, LAMP4, macrophage antigen CD68, macrosialin, SCARD1, scavenger receptor class D, member 1
储存 :
存放在4C。 不冻结
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。