产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Notch-1 Antibody (mN1A) - BSA Free
目录 :
NB100-78486
规格 :
0.1 ml (also 0.025 ml)
价格 :
449美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
mN1A
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 10
参考文献
Alghamdi T, Krentz N, Smith N, Spigelman A, Rajesh V, Jha A, et al. Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding. Mol Metab. 2022;66:101621 pubmed 出版商
Gong M, Yan F, Yu L, Li F. A dopamine-methacrylated hyaluronic acid hydrogel as an effective carrier for stem cells in skin regeneration therapy. Cell Death Dis. 2022;13:738 pubmed 出版商
Bai J, Khajavi M, Sui L, Fu H, Tarakkad Krishnaji S, Birsner A, et al. Angiogenic responses in a 3D micro-engineered environment of primary endothelial cells and pericytes. Angiogenesis. 2020;: pubmed 出版商
Kang H, Yang K, Xiao L, Guo L, Guo C, Yan Y, et al. Osteoblast Hypoxia-Inducible Factor-1? Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway. Front Immunol. 2017;8:1312 pubmed 出版商
Singh N, Kotla S, Kumar R, Rao G. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling. EBioMedicine. 2015;2:1767-84 pubmed 出版商
Qiu H, Tang X, Ma J, Shaverdashvili K, Zhang K, Bedogni B. Notch1 Autoactivation via Transcriptional Regulation of Furin, Which Sustains Notch1 Signaling by Processing Notch1-Activating Proteases ADAM10 and Membrane Type 1 Matrix Metalloproteinase. Mol Cell Biol. 2015;35:3622-32 pubmed 出版商
Jundt F, Acikgoz O, Kwon S, Schwarzer R, Anagnostopoulos I, Wiesner B, et al. Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma. Leukemia. 2008;22:1587-94 pubmed 出版商
Sun H, Li L, Vercherat C, Gulbagci N, Acharjee S, Li J, et al. Stra13 regulates satellite cell activation by antagonizing Notch signaling. J Cell Biol. 2007;177:647-57 pubmed
De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm J, et al. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature. 1999;398:518-22 pubmed
Ray W, Yao M, Nowotny P, Mumm J, Zhang W, Wu J, et al. Evidence for a physical interaction between presenilin and Notch. Proc Natl Acad Sci U S A. 1999;96:3263-8 pubmed
图像
图像 1 :
Novus Biologicals NB100-78486 图像 1
Knockout Validated: Notch-1 Antibody (mN1A) [NB100-78486] - Lysates of HeLa human cervical epithelial carcinoma parental cell line and Notch-1 knockout (KO) HeLa cell line. PVDF membrane was probed with 2.0 ug/mL of Mouse Anti-Human Notch-1 Monoclonal Antibody (Catalog # NB100-78486) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog #HAF018). Specific band was detected for Notch-1 at approximately 110 kDa (as indicated) in the parental HeLa cell line, but is not detectable in the knockout HeLa cell line. This experiment was conducted under reducing conditions.
产品信息
品牌 :
Novus
MasterCode :
NB100-78486
SKU号 :
NB100-78486
产品名称 :
Notch-1 Antibody (mN1A) - BSA Free
描述 :
The Notch-1 Antibody (mN1A) - BSA Free from NB100-78486 is a nb100-78486 antibody to . This antibody reacts with cancer stem cells, golgi apparatus markers, growth and development, neuronal cell markers, neuroscience, signal transduction. The Notch-1 Antibody (mN1A) - BSA Free has been validated for the following applications: Q01705.
靶标 :
Notch-1
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
mN1A
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Mouse Notch1 protein [Uniprot: Q01705]
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
Human, Mouse, Rat (Negative)
特异性 :
Does not cross-react with Notch 2, 3, or 4
理论上的分子量 :
272.505 kDa
基因符号 :
NOTCH1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Knockout-Validated-NB100-78486-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Knockout-Validated-NB100-78486-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Western-Blot-NB100-78486-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Western-Blot-NB100-78486-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Immunocytochemistry-Immunofluorescence-NB100-78486-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Immunocytochemistry-Immunofluorescence-NB100-78486-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Immunohistochemistry-Paraffin-NB100-78486-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Immunohistochemistry-Paraffin-NB100-78486-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Flow-Cytometry-NB100-78486-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Notch-1-Antibody-(mN1A)-Flow-Cytometry-NB100-78486-img0007.jpg
accessionNumbers :
Q01705
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, CyTOF-ready, Knockout Validated
美元 :
449美元
别名 :
EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。