CRM1抗体 | Novus Biologicals NB100-79802 产品信息

产品简要

公司名称 :

Novus Biologicals

其他品牌 :

IMGENEX

产品类型 :

抗体

产品名称 :

CRM1抗体

NB100-79802

规格 :

0.1毫升

价格 :

449美元

克隆性 :

多克隆

宿主 :

domestic rabbit

共轭标签 :

未共轭

反应物种 :

人类, 小鼠, 大鼠

应用 :

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片

更多信息或购买 :

Novus Biologicals 产品网页

文章摘录数: 9

参考文献
Wang X, Fan D, Han Q, Liu Y, Miao H, Wang X, et al. Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia. Cancer Discov. 2023;13:724-745 pubmed 出版商
Gorostieta Salas E, Moreno Blas D, Gerónimo Olvera C, Cisneros B, Court F, Castro Obregon S. Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain. Oxid Med Cell Longev. 2021;2021:6682336 pubmed 出版商
Meiners A, Bäcker S, Hadrović I, Heid C, Beuck C, Ruiz Blanco Y, et al. Specific inhibition of the Survivin-CRM1 interaction by peptide-modified molecular tweezers. Nat Commun. 2021;12:1505 pubmed 出版商
Balukoff N, Ho J, Theodoridis P, Wang M, Bokros M, Llanio L, et al. A translational program that suppresses metabolism to shield the genome. Nat Commun. 2020;11:5755 pubmed 出版商
Agote Aran A, Schmucker S, Jerabkova K, Jmel Boyer I, Berto A, Pacini L, et al. Spatial control of nucleoporin condensation by fragile X-related proteins. EMBO J. 2020;39:e104467 pubmed 出版商
García Aguirre I, Alamillo Iniesta A, Rodríguez Pérez R, Vélez Aguilera G, Amaro Encarnación E, Jiménez Gutiérrez E, et al. Enhanced nuclear protein export in premature aging and rescue of the progeria phenotype by modulation of CRM1 activity. Aging Cell. 2019;18:e13002 pubmed 出版商
Shakhparonov M, Antipova N, Shender V, Shnaider P, Arapidi G, Pestov N, et al. Expression and Intracellular Localization of Paraoxonase 2 in Different Types of Malignancies. Acta Naturae. 2018;10:92-99 pubmed
Vélez Aguilera G, de Dios Gómez López J, Jiménez Gutiérrez G, Vásquez Limeta A, Laredo Cisneros M, Gomez P, et al. Control of nuclear ?-dystroglycan content is crucial for the maintenance of nuclear envelope integrity and function. Biochim Biophys Acta Mol Cell Res. 2018;1865:406-420 pubmed 出版商
Vercruysse T, De Bie J, Neggers J, Jacquemyn M, Vanstreels E, Schmid Burgk J, et al. The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia. Clin Cancer Res. 2017;23:2528-2541 pubmed 出版商

图像

图像 1 :

Western Blot: CRM1 Antibody [NB100-79802] - Detection of Human and Mouse CRM1 by Western Blot. Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, Jurkat, and mouse TCMK-1 cells. Antibodies: Affinity purified rabbit anti-CRM1 antibody NB100-79802 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

产品信息

品牌 :

Novus Biologicals, a Bio-Techne Brand

catalog number base :

NB100-79802

SKU号 :

NB100-79802

产品名称 :

CRM1抗体

描述 :

The CRM1 Antibody from Novus is a rabbit polyclonal antibody to CRM1. This antibody reacts with human, mouse, rat. The CRM1 Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.

靶标 :

CRM1

类别 :

一抗

单位尺寸 :

0.1毫升

缓冲液 :

三羟甲基氨基甲烷柠檬酸盐/磷酸盐(pH值7.0-8.0)

克隆性 :

多克隆

浓度 :

1.0毫克/毫升

共轭标签 :

未共轭

宿主 :

兔

免疫原 :

The immunogen recognized by this antibody maps to a region between residue 1025 and the C-terminus (residue 1071) of human Chromosome Region Maintenance 1 (Exportin 1) (NP_003391.1).

抗体亚型 :

IgG

纯度 :

免疫原亲和纯化

物种 :

人类, 小鼠, 大鼠

理论上的分子量 :

123 kDa

基因符号 :

XPO1

accessionNumbers :

O14980

应用 :

Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin

美元 :

449美元

别名 :

Chromosome region maintenance 1 protein homolog, DKFZp686B1823, emb, exp1, exportin 1 (CRM1 homolog, yeast), exportin 1 (CRM1, yeast, homolog), exportin-1, Exportin-1 (required for chromosome region maintenance), yeast, homolog

储存 :

存放在4C。不冻结

更多信息或购买 :

Novus Biologicals 产品网页

公司信息

Novus Biologicals

10771 E Easter Ave
Centennial, CO 80112

technical@novusbio.com

https://www.novusbio.com

1-888-506-6887 303-730-1950

公司总部: 美国

Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。