产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
nNOS抗体
目录 :
NB100-858
规格 :
0.1毫克
价格 :
329美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
克隆名称 :
mN1A
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 13
参考文献
Auta J, Gatta E, Davis J, Zhang H, Pandey S, Guidotti A. Essential role for neuronal nitric oxide synthase in acute ethanol-induced motor impairment. Nitric Oxide. 2020;100-101:50-56 pubmed 出版商
Krawchuk M, Ruff C, Yang X, Ross S, Vazquez A. Optogenetic assessment of VIP, PV, SOM and NOS inhibitory neuron activity and cerebral blood flow regulation in mouse somato-sensory cortex. J Cereb Blood Flow Metab. 2020;40:1427-1440 pubmed 出版商
Brokhman I, Xu J, Coles B, Razavi R, Engert S, Lickert H, et al. Dual embryonic origin of the mammalian enteric nervous system. Dev Biol. 2019;445:256-270 pubmed 出版商
Bianco F, Eisenman S, Colmenares Aguilar M, Bonora E, Clavenzani P, Linden D, et al. Expression of RAD21 immunoreactivity in myenteric neurons of the human and mouse small intestine. Neurogastroenterol Motil. 2018;30:e13429 pubmed 出版商
Kang H, Yang K, Xiao L, Guo L, Guo C, Yan Y, et al. Osteoblast Hypoxia-Inducible Factor-1? Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway. Front Immunol. 2017;8:1312 pubmed 出版商
Carbone S, Jovanovska V, Brookes S, Nurgali K. Electrophysiological and morphological changes in colonic myenteric neurons from chemotherapy-treated patients: a pilot study. Neurogastroenterol Motil. 2016;28:975-84 pubmed 出版商
Singh N, Kotla S, Kumar R, Rao G. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling. EBioMedicine. 2015;2:1767-84 pubmed 出版商
Robinson A, Miller S, Payne N, Boyd R, Sakkal S, Nurgali K. Neuroprotective Potential of Mesenchymal Stem Cell-Based Therapy in Acute Stages of TNBS-Induced Colitis in Guinea-Pigs. PLoS ONE. 2015;10:e0139023 pubmed 出版商
Petrie C, Armitage M, Kawaja M. Myenteric expression of nerve growth factor and the p75 neurotrophin receptor regulate axonal remodeling as a consequence of colonic inflammation in mice. Exp Neurol. 2015;271:228-40 pubmed 出版商
Jundt F, Acikgoz O, Kwon S, Schwarzer R, Anagnostopoulos I, Wiesner B, et al. Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma. Leukemia. 2008;22:1587-94 pubmed 出版商
Sun H, Li L, Vercherat C, Gulbagci N, Acharjee S, Li J, et al. Stra13 regulates satellite cell activation by antagonizing Notch signaling. J Cell Biol. 2007;177:647-57 pubmed
De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm J, et al. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature. 1999;398:518-22 pubmed
Ray W, Yao M, Nowotny P, Mumm J, Zhang W, Wu J, et al. Evidence for a physical interaction between presenilin and Notch. Proc Natl Acad Sci U S A. 1999;96:3263-8 pubmed
图像
图像 1 :
Novus Biologicals NB100-858 图像 1
Immunocytochemistry/Immunofluorescence: nNOS Antibody [NB100-858] - Immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).
产品信息
品牌 :
Novus
SKU号 :
NB100-858
产品名称 :
nNOS抗体
单位尺寸 :
0.1毫克
描述 :
The nNOS Antibody from Novus is a goat polyclonal antibody to nNOS. This antibody reacts with human, mouse, rat, guinea pig. The nNOS Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen, Peptide ELISA, Immunohistochemistry Whole-Mount.
靶标 :
nNOS
类别 :
一抗
缓冲液 :
三羟甲基氨基甲烷盐溶液(20 mM三羟甲基氨基甲烷pH值7.3, 150 mM氯化钠), 0.5% BSA
克隆性 :
多克隆
浓度 :
0.5毫克/毫升
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Synthetic peptide with sequence ESKKDTDEVFSS, representing the C-terminus of the human protein (residues 1423-1434) according to NP_000611.
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠, 豚鼠
储存 :
存放在-20C。 避免冻融循环
用途 :
Successful use in ICC/IF has been reported in the literature (PMID: 20140458). It has also been used succesfully in IHC (PMID: 20140458). Use in IHC-Frozen and IHC-whole mount reported in scientific literature (PMID 24728885). Use in Western Blot reported in scientific literature (PMID: 32278831).
理论上的分子量 :
161 kDa
基因符号 :
NOS1
catalog number base :
NB100-858
accessionNumbers :
P29475, NP_000611.1, NP_001191147.1, NP_001191142.1
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen, Peptide ELISA, Immunohistochemistry Whole-Mount
美元 :
329美元
default size :
TRUE
别名 :
bNOS, brain, Constitutive NOS, EC 1.14.13.39, IHPS1, Neuronal NOS, nitric oxide synthase 1 (neuronal), N-NOS, nNOSNOS type I, NOS, Peptidyl-cysteine S-nitrosylase NOS1
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。