产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Hepatic Sinusoidal Endothelial Cells Antibody (SE-1)
目录 :
NB110-68095
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
种子-1
反应物种 :
小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 77
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 大鼠
Mollbrink A, Augsten M, Hultcrantz R, Eriksson L, Stål P. Sorafenib prolongs liver regeneration after hepatic resection in rats. J Surg Res. 2013;184:847-54 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫组化; 小鼠
Zuo D, Yu X, Guo C, Wang H, Qian J, Yi H, et al. Scavenger receptor A restrains T-cell activation and protects against concanavalin A-induced hepatic injury. Hepatology. 2013;57:228-38 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫组化; 小鼠
Ellett J, Atkinson C, Evans Z, Amani Z, Balish E, Schmidt M, et al. Toll-like receptor 4 knockout mice are protected from endothelial overactivation in the absence of Kupffer cells after total hepatic ischemia/reperfusion. Liver Transpl. 2011;17:1089-98 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫组化; 小鼠
Ellett J, Atkinson C, Evans Z, Amani Z, Balish E, Schmidt M, et al. Murine Kupffer cells are protective in total hepatic ischemia/reperfusion injury with bowel congestion through IL-10. J Immunol. 2010;184:5849-58 pubmed 出版商
  • 免疫组化; 大鼠
Braet F, Wisse E. Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review. Comp Hepatol. 2002;1:1 pubmed
  • 免疫组化; 大鼠
  • 免疫印迹; 大鼠
Tokairin T, Nishikawa Y, Doi Y, Watanabe H, Yoshioka T, Su M, et al. A highly specific isolation of rat sinusoidal endothelial cells by the immunomagnetic bead method using SE-1 monoclonal antibody. J Hepatol. 2002;36:725-33 pubmed
  • 免疫细胞化学; 大鼠
Morita M, Qun W, Watanabe H, Doi Y, Mori M, Enomoto K. Analysis of the sinusoidal endothelial cell organization during the developmental stage of the fetal rat liver using a sinusoidal endothelial cell specific antibody, SE-1. Cell Struct Funct. 1998;23:341-8 pubmed
  • 免疫组化; 大鼠
  • 免疫印迹; 大鼠
Ohmura T, Enomoto K, Satoh H, Sawada N, Mori M. Establishment of a novel monoclonal antibody, SE-1, which specifically reacts with rat hepatic sinusoidal endothelial cells. J Histochem Cytochem. 1993;41:1253-7 pubmed
Gil M, Khouri L, Raurell I, Rafael D, Andrade F, Abasolo I, et al. Optimization of Statin-Loaded Delivery Nanoparticles for Treating Chronic Liver Diseases by Targeting Liver Sinusoidal Endothelial Cells. Pharmaceutics. 2023;15: pubmed 出版商
Tian C, Li L, Fan L, Brown A, Norris E, Morrison M, et al. A hepatoprotective role of peritumoral non-parenchymal cells in early liver tumorigenesis. Dis Model Mech. 2023;16: pubmed 出版商
You K, Wang Y, Chen X, Yang Z, Chen Y, Tan S, et al. Neutralizing serum amyloid a protects against sinusoidal endothelial cell damage and platelet aggregation during acetaminophen-induced liver injury. Biochem Biophys Res Commun. 2023;639:20-28 pubmed 出版商
Bhandari S, Li R, Simon Santamaria J, McCourt P, Johansen S, Smedsrød B, et al. Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages. BMC Mol Cell Biol. 2020;21:85 pubmed 出版商
Nakura M, Miyashita T, Yamamoto Y, Takada S, Kanou S, Tajima H, et al. Inhibitory Effects of Beraprost Sodium in Murine Hepatic Sinusoidal Obstruction Syndrome. Anticancer Res. 2020;40:5171-5180 pubmed 出版商
Maruyama S, Kono H, Furuya S, Shimizu H, Saito R, Shoda K, et al. Platelet C-Type Lectin-Like Receptor 2 Reduces Cholestatic Liver Injury in Mice. Am J Pathol. 2020;190:1833-1842 pubmed 出版商
Kanou S, Miyashita T, Yamamoto Y, Takada S, Nakura M, Okazaki M, et al. Prophylactic Effect of Recombinant Human Soluble Thrombomodulin for Hepatic Sinusoidal Obstruction Syndrome Model Mice. In Vivo. 2020;34:1037-1045 pubmed 出版商
Wang C, Teo C, Sabapathy K. p53-Related Transcription Targets of TAp73 in Cancer Cells-Bona Fide or Distorted Reality?. Int J Mol Sci. 2020;21: pubmed 出版商
de Vries R, Pendexter C, Cronin S, Marques B, Hafiz E, Muzikansky A, et al. Cell release during perfusion reflects cold ischemic injury in rat livers. Sci Rep. 2020;10:1102 pubmed 出版商
Kumar S, Talluri S, Pal J, Yuan X, Lu R, Nanjappa P, et al. Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance. Blood Cancer J. 2018;8:92 pubmed 出版商
Makino E, Gutmann V, Kosnopfel C, Niessner H, Forschner A, Garbe C, et al. Melanoma cells resistant towards MAPK inhibitors exhibit reduced TAp73 expression mediating enhanced sensitivity to platinum-based drugs. Cell Death Dis. 2018;9:930 pubmed 出版商
Oldani G, Peloso A, Vijgen S, Wilson E, Slits F, Gex Q, et al. Chimeric liver transplantation reveals interspecific graft remodelling. J Hepatol. 2018;69:1025-1036 pubmed 出版商
Yang L, Yang X, Tang Y, Zhang D, Zhu L, Wang S, et al. Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response. Mol Med Rep. 2018;17:7545-7552 pubmed 出版商
Serra M, Marongiu M, Contini A, Miki T, Cadoni E, Laconi E, et al. Evidence of Amniotic Epithelial Cell Differentiation toward Hepatic Sinusoidal Endothelial Cells. Cell Transplant. 2018;27:23-30 pubmed 出版商
Papaspyropoulos A, Bradley L, Thapa A, Leung C, Toskas K, Koennig D, et al. RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73. Nat Commun. 2018;9:424 pubmed 出版商
Boylan J, Francois Vaughan H, Gruppuso P, Sanders J. Engraftment and Repopulation Potential of Late Gestation Fetal Rat Hepatocytes. Transplantation. 2017;101:2349-2359 pubmed 出版商
Lee T, Pelletier J. Dependence of p53-deficient cells on the DHX9 DExH-box helicase. Oncotarget. 2017;8:30908-30921 pubmed 出版商
Gonzalez R, De La Rosa A, Rufini A, Rodríguez Hernández M, Navarro Villarán E, Marchal T, et al. Role of p63 and p73 isoforms on the cell death in patients with hepatocellular carcinoma submitted to orthotopic liver transplantation. PLoS ONE. 2017;12:e0174326 pubmed 出版商
Kono H, Fujii H, Suzuki Inoue K, Inoue O, Furuya S, Hirayama K, et al. The platelet-activating receptor C-type lectin receptor-2 plays an essential role in liver regeneration after partial hepatectomy in mice. J Thromb Haemost. 2017;15:998-1008 pubmed 出版商
Prabhu V, Hong B, Allen J, Zhang S, Lulla A, Dicker D, et al. Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation. Cancer Res. 2016;76:1989-99 pubmed 出版商
Brahimi Horn M, Lacas Gervais S, Adaixo R, Ilc K, Rouleau M, Notte A, et al. Local mitochondrial-endolysosomal microfusion cleaves voltage-dependent anion channel 1 to promote survival in hypoxia. Mol Cell Biol. 2015;35:1491-505 pubmed 出版商
El Machhour F, Keuylian Z, Kavvadas P, Dussaule J, Chatziantoniou C. Activation of Notch3 in Glomeruli Promotes the Development of Rapidly Progressive Renal Disease. J Am Soc Nephrol. 2015;26:1561-75 pubmed 出版商
Venkatanarayan A, Raulji P, Norton W, Chakravarti D, Coarfa C, Su X, et al. IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo. Nature. 2015;517:626-30 pubmed 出版商
Chowdhury P, Lin G, Liu K, Song Y, Lin F, Lin W. Targeting TopBP1 at a convergent point of multiple oncogenic pathways for cancer therapy. Nat Commun. 2014;5:5476 pubmed 出版商
Lu H, Yan C, Quan X, Yang X, Zhang J, Bian Y, et al. CK2 phosphorylates and inhibits TAp73 tumor suppressor function to promote expression of cancer stem cell genes and phenotype in head and neck cancer. Neoplasia. 2014;16:789-800 pubmed 出版商
Bale S, Golberg I, Jindal R, McCarty W, Luitje M, Hegde M, et al. Long-term coculture strategies for primary hepatocytes and liver sinusoidal endothelial cells. Tissue Eng Part C Methods. 2015;21:413-22 pubmed 出版商
Nakadate K, Motojima K, Tanaka Nakadate S. Dilatation of sinusoidal capillary and swelling of sinusoidal fenestration in obesity: an ultrastructural study. Ultrastruct Pathol. 2015;39:30-7 pubmed 出版商
Zoric A, Horvat A, Slade N. Differential effects of diverse p53 isoforms on TAp73 transcriptional activity and apoptosis. Carcinogenesis. 2013;34:522-9 pubmed 出版商
Malatesta M, Peschiaroli A, Memmi E, Zhang J, Antonov A, Green D, et al. The Cul4A-DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity. Oncogene. 2013;32:4721-6 pubmed 出版商
Santag S, Jager W, Karsten C, Kati S, Pietrek M, Steinemann D, et al. Recruitment of the tumour suppressor protein p73 by Kaposi's Sarcoma Herpesvirus latent nuclear antigen contributes to the survival of primary effusion lymphoma cells. Oncogene. 2013;32:3676-85 pubmed 出版商
Brune M, Muller M, Melino G, Bierhaus A, Schilling T, Nawroth P. Depletion of the receptor for advanced glycation end products (RAGE) sensitizes towards apoptosis via p53 and p73 posttranslational regulation. Oncogene. 2013;32:1460-8 pubmed 出版商
Zhou M, Xu A, Tam P, Lam K, Huang B, Liang Y, et al. Upregulation of UCP2 by adiponectin: the involvement of mitochondrial superoxide and hnRNP K. PLoS ONE. 2012;7:e32349 pubmed 出版商
Hu X, Wu N, Xia P, Yu S, Sun F, Chen J. Correlation between low-level expression of the tumor suppressor gene TAp73 and the chemoresistance of human glioma stem cells. Cancer Chemother Pharmacol. 2012;69:1205-12 pubmed 出版商
Agostini M, Tucci P, Steinert J, Shalom Feuerstein R, Rouleau M, Aberdam D, et al. microRNA-34a regulates neurite outgrowth, spinal morphology, and function. Proc Natl Acad Sci U S A. 2011;108:21099-104 pubmed 出版商
Jankowski V, Tölle M, Santos R, Günthner T, Krause E, Beyermann M, et al. Angioprotectin: an angiotensin II-like peptide causing vasodilatory effects. FASEB J. 2011;25:2987-95 pubmed 出版商
Mair W. Doubling the dose. PLoS Biol. 2011;9:e1001017 pubmed 出版商
Tebbi A, Guittet O, Cottet M, Vesin M, Lepoivre M. TAp73 induction by nitric oxide: regulation by checkpoint kinase 1 (CHK1) and protection against apoptosis. J Biol Chem. 2011;286:7873-84 pubmed 出版商
Kruewel T, Schenone S, Radi M, Maga G, Rohrbeck A, Botta M, et al. Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers. PLoS ONE. 2010;5:e14143 pubmed 出版商
Tonino S, van Laar J, Van Oers M, Wang J, Eldering E, Kater A. ROS-mediated upregulation of Noxa overcomes chemoresistance in chronic lymphocytic leukemia. Oncogene. 2011;30:701-13 pubmed 出版商
Klein A, Maldonado C, Vargas L, Gonzalez M, Robledo F, Perez de Arce K, et al. Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons. Neurobiol Dis. 2011;41:209-18 pubmed 出版商
Wierda W, Castro J, Aguillon R, Sampath D, Jalayer A, McMannis J, et al. A phase I study of immune gene therapy for patients with CLL using a membrane-stable, humanized CD154. Leukemia. 2010;24:1893-900 pubmed 出版商
Arfaoui A, Kriaa L, El Hadj O, Ben Hmida M, Khiari M, Khalfallah T, et al. Association of a p73 exon 2 GC/AT polymorphism with colorectal cancer risk and survival in Tunisian patients. Virchows Arch. 2010;457:359-68 pubmed 出版商
Ma Y, Yu W, Trump D, Johnson C. 1,25D3 enhances antitumor activity of gemcitabine and cisplatin in human bladder cancer models. Cancer. 2010;116:3294-303 pubmed 出版商
Cho M, Chan I, Flores E. ?Np63 transcriptionally regulates brachyury, a gene with diverse roles in limb development, tumorigenesis and metastasis. Cell Cycle. 2010;9:2434-41 pubmed
Rosenbluth J, Johnson K, Tang L, Triplett T, Pietenpol J. Evaluation of p63 and p73 antibodies for cross-reactivity. Cell Cycle. 2009;8:3702-6 pubmed
Alonso R, Lopez Guerra M, Upshaw R, Bantia S, Smal C, Bontemps F, et al. Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM. Blood. 2009;114:1563-75 pubmed 出版商
Marqués García F, Ferrandiz N, Fernández Alonso R, González Cano L, Herreros Villanueva M, Rosa Garrido M, et al. p73 plays a role in erythroid differentiation through GATA1 induction. J Biol Chem. 2009;284:21139-56 pubmed 出版商
Liu K, Bellam N, Lin H, Wang B, Stockard C, Grizzle W, et al. Regulation of p53 by TopBP1: a potential mechanism for p53 inactivation in cancer. Mol Cell Biol. 2009;29:2673-93 pubmed 出版商
Tomasini R, Tsuchihara K, Tsuda C, Lau S, Wilhelm M, Rufini A, et al. TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proc Natl Acad Sci U S A. 2009;106:797-802 pubmed 出版商
Sampath D, Calin G, Puduvalli V, Gopisetty G, Taccioli C, Liu C, et al. Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation. Blood. 2009;113:3744-53 pubmed 出版商
Ma Y, Yu W, Hershberger P, Flynn G, Kong R, Trump D, et al. 1alpha,25-Dihydroxyvitamin D3 potentiates cisplatin antitumor activity by p73 induction in a squamous cell carcinoma model. Mol Cancer Ther. 2008;7:3047-55 pubmed 出版商
Marinovic Terzic I, Yoshioka Yamashita A, Shimodaira H, Avdievich E, Hunton I, Kolodner R, et al. Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q. Proc Natl Acad Sci U S A. 2008;105:13993-8 pubmed 出版商
Rosenbluth J, Mays D, Pino M, Tang L, Pietenpol J. A gene signature-based approach identifies mTOR as a regulator of p73. Mol Cell Biol. 2008;28:5951-64 pubmed 出版商
Alvarez A, Klein A, Castro J, Cancino G, Amigo J, Mosqueira M, et al. Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease. FASEB J. 2008;22:3617-27 pubmed 出版商
Lunghi P, Giuliani N, Mazzera L, Lombardi G, Ricca M, Corradi A, et al. Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways. Blood. 2008;112:2450-62 pubmed 出版商
Cancino G, Toledo E, Leal N, Hernandez D, Yévenes L, Inestrosa N, et al. STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's beta-amyloid deposits. Brain. 2008;131:2425-42 pubmed 出版商
Li L, Morales J, Hwang A, Wagner M, Boothman D. DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis. J Biol Chem. 2008;283:21394-403 pubmed 出版商
Mor I, Sklan E, Podoly E, Pick M, Kirschner M, Yogev L, et al. Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility. J Cell Mol Med. 2008;12:479-95 pubmed 出版商
Kurihara A, Nagoshi H, Yabuki M, Okuyama R, Obinata M, Ikawa S. Ser46 phosphorylation of p53 is not always sufficient to induce apoptosis: multiple mechanisms of regulation of p53-dependent apoptosis. Genes Cells. 2007;12:853-61 pubmed
Bozzetti C, Nizzoli R, Musolino A, Martella E, Crafa P, Lagrasta C, et al. p73 and p53 pathway in human breast cancers. J Clin Oncol. 2007;25:1451-3; author reply 1453-4 pubmed
Limesand K, Schwertfeger K, Anderson S. MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells. Mol Cell Biol. 2006;26:8840-56 pubmed
Thottassery J, Westbrook L, Someya H, Parker W. c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-beta-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells. Mol Cancer Ther. 2006;5:400-10 pubmed
Dominguez G, Garcia J, Peña C, Silva J, Garcia V, Martínez L, et al. DeltaTAp73 upregulation correlates with poor prognosis in human tumors: putative in vivo network involving p73 isoforms, p53, and E2F-1. J Clin Oncol. 2006;24:805-15 pubmed
Cui R, Nguyen T, Taube J, Stratton S, Feuerman M, Barton M. Family members p53 and p73 act together in chromatin modification and direct repression of alpha-fetoprotein transcription. J Biol Chem. 2005;280:39152-60 pubmed
Sayan A, Paradisi A, Vojtesek B, Knight R, Melino G, Candi E. New antibodies recognizing p73: comparison with commercial antibodies. Biochem Biophys Res Commun. 2005;330:186-93 pubmed
Bernassola F, Salomoni P, Oberst A, Di Como C, Pagano M, Melino G, et al. Ubiquitin-dependent degradation of p73 is inhibited by PML. J Exp Med. 2004;199:1545-57 pubmed
Frasca F, Vella V, Aloisi A, Mandarino A, Mazzon E, Vigneri R, et al. p73 tumor-suppressor activity is impaired in human thyroid cancer. Cancer Res. 2003;63:5829-37 pubmed
Vella V, Zhu J, Frasca F, Li C, Vigneri P, Vigneri R, et al. Exclusion of c-Abl from the nucleus restrains the p73 tumor suppression function. J Biol Chem. 2003;278:25151-7 pubmed
Shimodaira H, Yoshioka Yamashita A, Kolodner R, Wang J. Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. Proc Natl Acad Sci U S A. 2003;100:2420-5 pubmed
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB110-68095
SKU号 :
NB110-68095
产品名称 :
Hepatic Sinusoidal Endothelial Cells Antibody (SE-1)
描述 :
The Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) from Novus is a mouse monoclonal antibody to Hepatic Sinusoidal Endothelial Cells. This antibody reacts with human, mouse, rat. The Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
靶标 :
Hepatic Sinusoidal Endothelial Cells
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
种子-1
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Rat Hepatic Sinusoidal Endothelial Cells
抗体亚型 :
IgG2a Kappa
纯度 :
蛋白质A纯化
物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 流式细胞仪, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡, 免疫组化冷冻
美元 :
399美元
别名 :
Hepatic cells, Hepatic Sinusoidal Endothelial Cells, HSE, SE1, Sinusoidal Endothelial Cells
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。