产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Tenascin C Antibody (4C8MS) - BSA Free
目录 :
NB110-68136
规格 :
0.1 ml (also 0.025 ml)
价格 :
419美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4C8MS
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 70
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 1b
Bhattacharyya S, Wang W, Morales Nebreda L, Feng G, Wu M, Zhou X, et al. Tenascin-C drives persistence of organ fibrosis. Nat Commun. 2016;7:11703 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫组化-石蜡切片; 大鼠
de Sousa A, Gurgel C, Ramos E, Trindade R, de Faro Valverde L, Carneiro T, et al. Infrared LED light therapy influences the expression of fibronectin and tenascin in skin wounds of malnourished rats--a preliminary study. Acta Histochem. 2014;116:1185-91 pubmed 出版商
  • 免疫印迹; 小鼠
James M, Ross A, Nicola T, Steele C, Ambalavanan N. VARA attenuates hyperoxia-induced impaired alveolar development and lung function in newborn mice. Am J Physiol Lung Cell Mol Physiol. 2013;304:L803-12 pubmed 出版商
  • 免疫组化; 大鼠
Ago K, Kemmochi S, Morita R, Yafune A, Shiraki A, Mitsumori K, et al. Direct progression of capsular invasive carcinomas from subcapsular focal hyperplasias induced by hypothyroidism-mediated tumor promotion in a rat two-stage thyroid carcinogenesis model. J Cancer Res Clin Oncol. 2013;139:395-401 pubmed 出版商
  • 免疫组化; 大鼠
Kemmochi S, Yamamichi S, Shimamoto K, Onda N, Hasumi K, Suzuki K, et al. Lac color inhibits development of rat thyroid carcinomas through targeting activation of plasma hyaluronan-binding protein. Exp Biol Med (Maywood). 2012;237:728-38 pubmed 出版商
  • 免疫组化; 大鼠
Kemmochi S, Shimamoto K, Shiraki A, Onda N, Hasumi K, Suzuki K, et al. Promoting effects of carminic acid-enriched cochineal extracts on capsular invasive thyroid carcinomas through targeting activation of angiogenesis in rats. J Toxicol Sci. 2012;37:475-82 pubmed
  • 免疫组化-石蜡切片; 大鼠
Yamamoto M, Okui N, Tatebe M, Shinohara T, Hirata H. Regeneration of the perineurium after microsurgical resection examined with immunolabeling for tenascin-C and alpha smooth muscle actin. J Anat. 2011;218:413-25 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Balasenthil S, Chen N, Lott S, Chen J, Carter J, Grizzle W, et al. A migration signature and plasma biomarker panel for pancreatic adenocarcinoma. Cancer Prev Res (Phila). 2011;4:137-49 pubmed 出版商
  • 免疫组化-冰冻切片; 人类
  • 免疫组化; 人类
  • 酶联免疫吸附测定; 人类
Richter P, Tost M, Franz M, Altendorf Hofmann A, Junker K, Borsi L, et al. B and C domain containing tenascin-C: urinary markers for invasiveness of urothelial carcinoma of the urinary bladder?. J Cancer Res Clin Oncol. 2009;135:1351-8 pubmed 出版商
  • 免疫组化; 人类
El Karef A, Kaito M, Tanaka H, Ikeda K, Nishioka T, Fujita N, et al. Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C. J Hepatol. 2007;46:664-73 pubmed
  • 免疫组化-石蜡切片; 人类
Kääriäinen E, Nummela P, Soikkeli J, Yin M, Lukk M, Jahkola T, et al. Switch to an invasive growth phase in melanoma is associated with tenascin-C, fibronectin, and procollagen-I forming specific channel structures for invasion. J Pathol. 2006;210:181-91 pubmed
  • 免疫组化-石蜡切片; 小鼠
Tamaoki M, Imanaka Yoshida K, Yokoyama K, Nishioka T, Inada H, Hiroe M, et al. Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury. Am J Pathol. 2005;167:71-80 pubmed
  • 免疫组化-石蜡切片; 人类
  • 免疫印迹; 人类
Tsunoda T, Inada H, Kalembeyi I, Imanaka Yoshida K, Sakakibara M, Okada R, et al. Involvement of large tenascin-C splice variants in breast cancer progression. Am J Pathol. 2003;162:1857-67 pubmed
Li J, Sina A, Antaw F, Fielding D, M xf6 ller A, Lobb R, et al. Digital Decoding of Single Extracellular Vesicle Phenotype Differentiates Early Malignant and Benign Lung Lesions. Adv Sci (Weinh). 2022;10:e2204207 pubmed 出版商
Ni Y, Wu G, Cai J, Zhang R, Zheng Y, Liu J, et al. Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation. Int J Biol Sci. 2022;18:5168-5184 pubmed 出版商
Louisthelmy R, Burke B, Cornelison R. Brain cancer cell-derived matrices and effects on astrocyte migration. Cells Tissues Organs. 2022;: pubmed 出版商
Dorchin Ashkenazi H, Ginat Koton R, Gabet Y, Klein Y, Chaushu S, Dorchin H, et al. The Balance between Orthodontic Force and Radiation in the Jawbone: Microstructural, Histological, and Molecular Study in a Rat Model. Biology (Basel). 2021;10: pubmed 出版商
Lee Y, Ricky S, Lim T, Kim H, Lee E, Song Y, et al. An atmospheric plasma jet induces expression of wound healing genes in progressive burn wounds in a comb burn rat model: a pilot study. J Burn Care Res. 2021;: pubmed 出版商
Otsuka T, Mengsteab P, Laurencin C. Control of mesenchymal cell fate via application of FGF-8b in vitro. Stem Cell Res. 2021;51:102155 pubmed 出版商
Gao Q, Wei A, Chen F, Chen X, Ding W, Ding Z, et al. Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice. Pharmacol Res. 2020;160:105059 pubmed 出版商
Werkman I, Kövilein J, de Jonge J, Baron W. Impairing committed cholesterol biosynthesis in white matter astrocytes, but not grey matter astrocytes, enhances in vitro myelination. J Neurochem. 2020;: pubmed 出版商
Wang D, Hiebl V, Schachner D, Ladurner A, Heiss E, Atanasov A, et al. Soraphen A enhances macrophage cholesterol efflux via indirect LXR activation and ABCA1 upregulation. Biochem Pharmacol. 2020;177:114022 pubmed 出版商
Marshall J, Courage E, Elliott R, Fitzpatrick M, Kim A, Lopez Clavijo A, et al. THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation. PLoS ONE. 2020;15:e0233180 pubmed 出版商
Salonurmi T, Nabil H, Ronkainen J, Hyötyläinen T, Hautajärvi H, Savolainen M, et al. 4β-Hydroxycholesterol Signals From the Liver to Regulate Peripheral Cholesterol Transporters. Front Pharmacol. 2020;11:361 pubmed 出版商
Koga M, Kanaoka Y, Inada K, Omine S, Kataoka Y, Yamauchi A. Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages. J Pharmacol Sci. 2020;143:106-111 pubmed 出版商
Meng X, Yin J, Yu X, Guo Y. MicroRNA-205-5p Promotes Unstable Atherosclerotic Plaque Formation In Vivo. Cardiovasc Drugs Ther. 2020;34:25-39 pubmed 出版商
Haydont V, Neiveyans V, Perez P, Busson E, Lataillade J, Asselineau D, et al. Fibroblasts from the Human Skin Dermo-Hypodermal Junction are Distinct from Dermal Papillary and Reticular Fibroblasts and from Mesenchymal Stem Cells and Exhibit a Specific Molecular Profile Related to Extracellular Matrix Organization and Modeling. Cells. 2020;9: pubmed 出版商
Ishikawa K, Kohno R, Mori K, Murakami Y, Nakao S, Akiyama M, et al. Increased expression of periostin and tenascin-C in eyes with neovascular glaucoma secondary to PDR. Graefes Arch Clin Exp Ophthalmol. 2020;258:621-628 pubmed 出版商
Koga M, Kanaoka Y, Okamoto M, Nakao Y, Inada K, Takayama S, et al. Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression. J Pharmacol Sci. 2020;142:9-15 pubmed 出版商
Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020;28:202-216 pubmed 出版商
Urano Y, Ho Vo D, Hirofumi A, Noguchi N. 24(S)-Hydroxycholesterol induces ER dysfunction-mediated unconventional cell death. Cell Death Discov. 2019;5:113 pubmed 出版商
Wu A, Grela E, Wojtowicz K, Filipczak N, Hamon Y, Luchowski R, et al. ABCA1 transporter reduces amphotericin B cytotoxicity in mammalian cells. Cell Mol Life Sci. 2019;: pubmed 出版商
Wang H, Zhang X, Yu B, Peng X, Liu Y, Wang A, et al. Cyclodextrin Ameliorates the Progression of Atherosclerosis via Increasing High-Density Lipoprotein Cholesterol Plasma Levels and Anti-inflammatory Effects in Rabbits. J Cardiovasc Pharmacol. 2019;73:334-342 pubmed 出版商
Sedgeman L, Beysen C, Ramirez Solano M, Michell D, Sheng Q, Zhao S, et al. Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion. Sci Rep. 2019;9:3803 pubmed 出版商
Yuan C, Guo X, Zhou Q, Du F, Jiang W, Zhou X, et al. OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. Biochim Biophys Acta Mol Basis Dis. 2019;1865:161-180 pubmed 出版商
Nishino T, Horie T, Baba O, Sowa N, Hanada R, Kuwabara Y, et al. SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo. Arterioscler Thromb Vasc Biol. 2018;38:2460-2473 pubmed 出版商
Harris M, Hussain S, Inouye C, Castle A, Castle J. Reinterpretation of the localization of the ATP binding cassette transporter ABCG1 in insulin-secreting cells and insights regarding its trafficking and function. PLoS ONE. 2018;13:e0198383 pubmed 出版商
Qian K, Feng L, Sun Y, Xiong B, Ding Y, Han P, et al. Overexpression of Salusin-α Inhibits Vascular Intimal Hyperplasia in an Atherosclerotic Rabbit Model. Biomed Res Int. 2018;2018:8973986 pubmed 出版商
Wang L, Eftekhari P, Schachner D, Ignatova I, Palme V, Schilcher N, et al. Novel interactomics approach identifies ABCA1 as direct target of evodiamine, which increases macrophage cholesterol efflux. Sci Rep. 2018;8:11061 pubmed 出版商
Sonett J, Goldklang M, Sklepkiewicz P, Gerber A, Trischler J, Zelonina T, et al. A critical role for ABC transporters in persistent lung inflammation in the development of emphysema after smoke exposure. FASEB J. 2018;:fj201701381 pubmed 出版商
Ying F, Cai Y, Wong H, Chen X, Huang I, Vanhoutte P, et al. EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:1029-1040 pubmed 出版商
Wang D, Hiebl V, Ladurner A, Latkolik S, Bucar F, Heiß E, et al. 6-Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP-1-Derived Macrophages. Mol Nutr Food Res. 2018;:e1800011 pubmed 出版商
Becerril S, Rodriguez A, Catalan V, Méndez Giménez L, Ramirez B, Sainz N, et al. Targeted disruption of the iNOS gene improves adipose tissue inflammation and fibrosis in leptin-deficient ob/ob mice: role of tenascin C. Int J Obes (Lond). 2018;42:1458-1470 pubmed 出版商
Li Y, Shen S, Ding S, Wang L. Toll-like receptor 2 downregulates the cholesterol efflux by activating the nuclear factor-κB pathway in macrophages and may be a potential therapeutic target for the prevention of atherosclerosis. Exp Ther Med. 2018;15:198-204 pubmed 出版商
Cuffe H, Liu M, Key C, Boudyguina E, Sawyer J, Weckerle A, et al. Targeted Deletion of Adipocyte Abca1 (ATP-Binding Cassette Transporter A1) Impairs Diet-Induced Obesity. Arterioscler Thromb Vasc Biol. 2018;38:733-743 pubmed 出版商
Canfrán Duque A, Rotllan N, Zhang X, Fernández Fuertes M, Ramírez Hidalgo C, Araldi E, et al. Macrophage deficiency of miR-21 promotes apoptosis, plaque necrosis, and vascular inflammation during atherogenesis. EMBO Mol Med. 2017;9:1244-1262 pubmed 出版商
de Aguiar Vallim T, Lee E, Merriott D, Goulbourne C, Cheng J, Cheng A, et al. ABCG1 regulates pulmonary surfactant metabolism in mice and men. J Lipid Res. 2017;58:941-954 pubmed 出版商
Mariani M, Malm T, Lamb R, Jay T, Neilson L, Casali B, et al. Neuronally-directed effects of RXR activation in a mouse model of Alzheimer's disease. Sci Rep. 2017;7:42270 pubmed 出版商
Jiang M, Li X. Activation of PPAR? does not contribute to macrophage ABCA1 expression and ABCA1-mediated cholesterol efflux to apoAI. Biochem Biophys Res Commun. 2017;482:849-856 pubmed 出版商
Wang L, Palme V, Rotter S, Schilcher N, Cukaj M, Wang D, et al. Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages. Mol Nutr Food Res. 2017;61: pubmed 出版商
Janune D, Abd El Kader T, Aoyama E, Nishida T, Tabata Y, Kubota S, et al. Novel role of CCN3 that maintains the differentiated phenotype of articular cartilage. J Bone Miner Metab. 2017;35:582-597 pubmed 出版商
Cheng H, Gaddis D, Wu R, McSkimming C, Haynes L, Taylor A, et al. Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. J Clin Invest. 2016;126:3236-46 pubmed 出版商
Lai L, Azzam K, Lin W, Rai P, Lowe J, Gabor K, et al. MicroRNA-33 Regulates the Innate Immune Response via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains. J Biol Chem. 2016;291:19651-60 pubmed 出版商
Aryal B, Rotllan N, Araldi E, Ramírez C, He S, Chousterman B, et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 pubmed 出版商
Mostafa A, Hamdy N, Abdel Rahman S, El Mesallamy H. Effect of vildagliptin and pravastatin combination on cholesterol efflux in adipocytes. IUBMB Life. 2016;68:535-43 pubmed 出版商
Tarling E, Edwards P. Intracellular Localization of Endogenous Mouse ABCG1 Is Mimicked by Both ABCG1-L550 and ABCG1-P550-Brief Report. Arterioscler Thromb Vasc Biol. 2016;36:1323-7 pubmed 出版商
Zhang X, Hu J, Zhong L, Wang N, Yang L, Liu C, et al. Quercetin stabilizes apolipoprotein E and reduces brain A? levels in amyloid model mice. Neuropharmacology. 2016;108:179-92 pubmed 出版商
Leng S, Iwanowycz S, Saaoud F, Wang J, Wang Y, Sergin I, et al. Ursolic acid enhances macrophage autophagy and attenuates atherogenesis. J Lipid Res. 2016;57:1006-16 pubmed 出版商
Shi H, Mao X, Zhong Y, Liu Y, Zhao X, Yu K, et al. Lanatoside C Promotes Foam Cell Formation and Atherosclerosis. Sci Rep. 2016;6:20154 pubmed 出版商
Mostafa A, Hamdy N, El Mesallamy H, Abdel Rahman S. Glucagon-like peptide 1 (GLP-1)-based therapy upregulates LXR-ABCA1/ABCG1 cascade in adipocytes. Biochem Biophys Res Commun. 2015;468:900-5 pubmed 出版商
Matsuo K, Yamamoto S, Wakamatsu T, Takahashi Y, Kawamura K, Kaneko Y, et al. Increased Proinflammatory Cytokine Production and Decreased Cholesterol Efflux Due to Downregulation of ABCG1 in Macrophages Exposed to Indoxyl Sulfate. Toxins (Basel). 2015;7:3155-66 pubmed 出版商
Daffu G, Shen X, Senatus L, Thiagarajan D, Abedini A, Hurtado del Pozo C, et al. RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in Diabetes. Diabetes. 2015;64:4046-60 pubmed 出版商
Lee T, Lu K, Yu Y, Lee H, Tsai F. β Common Receptor Mediates Erythropoietin-Conferred Protection on OxLDL-Induced Lipid Accumulation and Inflammation in Macrophages. Mediators Inflamm. 2015;2015:439759 pubmed 出版商
de Boussac H, Maqdasy S, Trousson A, Zelcer N, Volle D, Lobaccaro J, et al. Enolase is regulated by Liver X Receptors. Steroids. 2015;99:266-71 pubmed 出版商
Park S, Paek J, Shin D, Lee J, Lim S, Kang Y. Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages. Int J Mol Med. 2015;35:957-65 pubmed 出版商
Zheng W, Mast N, Saadane A, Pikuleva I. Pathways of cholesterol homeostasis in mouse retina responsive to dietary and pharmacologic treatments. J Lipid Res. 2015;56:81-97 pubmed 出版商
Frisdal E, Le Lay S, Hooton H, Poupel L, Olivier M, Alili R, et al. Adipocyte ATP-binding cassette G1 promotes triglyceride storage, fat mass growth, and human obesity. Diabetes. 2015;64:840-55 pubmed 出版商
Janune D, Kubota S, Nishida T, Kawaki H, Perbal B, Iida S, et al. Novel effects of CCN3 that may direct the differentiation of chondrocytes. FEBS Lett. 2011;585:3033-40 pubmed 出版商
Guttery D, Shaw J, Lloyd K, Pringle J, Walker R. Expression of tenascin-C and its isoforms in the breast. Cancer Metastasis Rev. 2010;29:595-606 pubmed 出版商
Yoshimura H, Michishita M, Ohkusu Tsukada K, Takahashi K. Increased presence of stromal myofibroblasts and tenascin-C with malignant progression in canine mammary tumors. Vet Pathol. 2011;48:313-21 pubmed 出版商
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB110-68136
SKU号 :
NB110-68136
产品名称 :
Tenascin C Antibody (4C8MS) - BSA Free
描述 :
The Tenascin C Antibody (4C8MS) - BSA Free from Novus is a mouse monoclonal antibody to Tenascin C. This antibody reacts with human, mouse, rat, feline. The Tenascin C Antibody (4C8MS) - BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular), CyTOF-ready.
靶标 :
腱糖蛋白C
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
4C8MS
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Recombinant human Tenascin C [Swiss-Prot# P24821].
抗体亚型 :
IgG1
纯度 :
蛋白质A纯化
物种 :
人类, 小鼠, 大鼠, 猫
特异性 :
NB110-68136 specifically reacts with Domain B on FNIII repeats of Tenascin C
基因符号 :
TNC
accessionNumbers :
P24821
应用 :
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular), CyTOF-ready
美元 :
419美元
产品细节 :
Tenascin C is an extracellular matrix protein that is expressed in various tissues during development, disease or injury. Tenascin C inhibits HIV infection in immune cells by binding to a chemokine coreceptor site on the HIV-1 envelope protein, thereby blocking the virus' entry into the host cells. Tenascin C expression in the stroma of certain tumors is often associated with a poor prognosis.
别名 :
150-225, Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion, hexabrachion (tenascin C, cytotactin), hexabrachion (tenascin), HXBcytotactin, JI, MGC167029, Myotendinous antigen, neuronectin, tenascin, tenascin C, Tenascin-C, tenascin-C isoform 14/AD1/16, TN-C, TNGP
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。