产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Opsin 1 (Medium Wave) Antibody
目录 :
NB110-74730
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 13
参考文献
Su J, She K, Song L, Jin X, Li R, Zhao Q, et al. In vivo base editing rescues photoreceptors in a mouse model of retinitis pigmentosa. Mol Ther Nucleic Acids. 2023;31:596-609 pubmed 出版商
Chen B, Liou J, Wu J, Chen C, Yang S. Photoreceptor and vision protective effects of astragaloside IV in mice model with light-evoked retinal damage. Biomed Pharmacother. 2022;153:113404 pubmed 出版商
Wu J, Yang S, Ho Y, Chen C, Tasi B, Lee M, et al. The Functional Vision Restorative Effect of Crocin via the BDNF-TrkB Pathway: An In Vivo Study. Nutrients. 2022;14: pubmed 出版商
Choi E, Suh S, Foik A, Leinonen H, Newby G, Gao X, et al. In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration. Nat Commun. 2022;13:1830 pubmed 出版商
Miller L, Tarantini S, Nyúl Tóth Á, Johnston M, Martin T, Bullen E, et al. Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging. Front Aging Neurosci. 2022;14:788296 pubmed 出版商
Chen Y, Huang Y, Wu P, Chiang W, Wang P, Chen B. The Functional Vision Protection Effect of Danshensu via Dopamine D1 Receptors: In Vivo Study. Nutrients. 2021;13: pubmed 出版商
Leinonen H, Pham N, Boyd T, Santoso J, Palczewski K, Vinberg F. Homeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease. elife. 2020;9: pubmed 出版商
Strayve D, Makia M, Kakakhel M, Sakthivel H, Conley S, Al Ubaidi M, et al. ROM1 contributes to phenotypic heterogeneity in PRPH2-associated retinal disease. Hum Mol Genet. 2020;29:2708-2722 pubmed 出版商
Chakraborty D, Strayve D, Makia M, Conley S, Kakahel M, Al Ubaidi M, et al. Novel molecular mechanisms for Prph2-associated pattern dystrophy. FASEB J. 2020;34:1211-1230 pubmed 出版商
Pan M, Hu H, Wang R, Zhou Y, Zhang L, Wang C, et al. JNK1 Induces Notch1 Expression to Regulate Genes Governing Photoreceptor Production. Cells. 2019;8: pubmed 出版商
Leinonen H, Choi E, Gardella A, Kefalov V, Palczewski K. A Mixture of U.S. Food and Drug Administration-Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness. Invest Ophthalmol Vis Sci. 2019;60:1442-1453 pubmed 出版商
Conley S, Stuck M, Watson J, Zulliger R, Burnett J, Naash M. Prph2 initiates outer segment morphogenesis but maturation requires Prph2/Rom1 oligomerization. Hum Mol Genet. 2019;28:459-475 pubmed 出版商
Orban T, Leinonen H, Getter T, Dong Z, Sun W, Gao S, et al. A Combination of G Protein-Coupled Receptor Modulators Protects Photoreceptors from Degeneration. J Pharmacol Exp Ther. 2018;364:207-220 pubmed 出版商
图像
图像 1 :
Novus Biologicals NB110-74730 图像 1
Immunohistochemistry: Opsin 1 (Medium Wave) Antibody [NB110-74730] - Protection of the retina against light damage in Grk1-/- mice subjected to BLE (12.5 klux for 0.5 hours) 1 week prior to imaging. Drug combination (M+B+T) or vehicle was injected i.p. 0.5 hours prior to induction of light damage (replicates are presented in Table 2). Representative flat-mount retina image of typical M- (green) and S-cone (blue) populations in vehicle-treated mouse retinas 1 week after BLE. Dashed white lines show border between damaged and healthy site in cone population. M+B+T at a dose 10-1-0.5 mg/kg maintained cone population at ~95%, whereas ONL thickness (representative of rod population) with this dose was decreased by ~50%. M+B+T 50-5-2.5 mg/kg dose led to full protection in both rod and cone population. Image collected and cropped by CiteAb from the following publication (http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.19-26560) licensed under a CC-BY licence.
产品信息
品牌 :
Novus
MasterCode :
NB110-74730
SKU号 :
NB110-74730
产品名称 :
Opsin 1 (Medium Wave) Antibody
描述 :
The Opsin 1 (Medium Wave) Antibody from NB110-74730 is a nb110-74730 antibody to . This antibody reacts with gpcr. The Opsin 1 (Medium Wave) Antibody has been validated for the following applications: O35599.
靶标 :
Opsin 1 (Medium Wave)
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
Lyophilized from whole antisera
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
免疫原 :
A synthetic peptide from mouse Opsin 1 (Medium Wave) conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat.
抗体亚型 :
IgG
纯度 :
Unpurified
物种 :
小鼠, 大鼠
基因符号 :
OPN1MW
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-NB110-74730-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-NB110-74730-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-NB110-74730-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-NB110-74730-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Opsin-1-(Medium-Wave)-Antibody-Immunohistochemistry-Paraffin-NB110-74730-img0010.jpg
accessionNumbers :
O35599
应用 :
免疫印迹, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡, 免疫组化冷冻
美元 :
399美元
别名 :
GCP, GOP, Green cone photoreceptor pigment, Green-sensitive opsin, medium-wave-sensitive opsin 1, OPN1MW, opsin 1 (cone pigments), medium-wave-sensitive 2
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。