产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
NHE3/SLC9A3[p Ser552]抗体(14D5)
目录 :
NB110-81529
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
14D5
反应物种 :
primate, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Ozkucur N, Song B, Bola S, Zhang L, Reid B, Fu G, et al. NHE3 phosphorylation via PKC? marks the polarity and orientation of directionally migrating cells. Cell Mol Life Sci. 2014;71:4653-4663 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Perike S, Ozkucur N, Sharma P, Staroske W, Bläsche R, Barth K, et al. Phospho-NHE3 forms membrane patches and interacts with beta-actin to sense and maintain constant direction during cell migration. Exp Cell Res. 2014;324:13-29 pubmed 出版商
  • 免疫印迹; 人类
Liu T, Jose P. Gastrin induces sodium-hydrogen exchanger 3 phosphorylation and mTOR activation via a phosphoinositide 3-kinase-/protein kinase C-dependent but AKT-independent pathway in renal proximal tubule cells derived from a normotensive male human. Endocrinology. 2013;154:865-75 pubmed 出版商
  • 免疫印迹; 小鼠
Rieg T, Gerasimova M, Murray F, Masuda T, Tang T, Rose M, et al. Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice. Am J Physiol Renal Physiol. 2012;303:F963-71 pubmed 出版商
  • 流式细胞仪; 人类
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
  • 流式细胞仪; 大鼠
  • 免疫沉淀; 大鼠
  • 免疫细胞化学; 大鼠
  • 免疫印迹; 大鼠
Ozkucur N, Perike S, Sharma P, Funk R. Persistent directional cell migration requires ion transport proteins as direction sensors and membrane potential differences in order to maintain directedness. BMC Cell Biol. 2011;12:4 pubmed 出版商
  • 免疫沉淀; primate
  • 免疫印迹; primate
Dynia D, Steinmetz A, Kocinsky H. NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase. Am J Physiol Renal Physiol. 2010;298:F745-53 pubmed 出版商
  • 免疫印迹; 大鼠
Kocinsky H, Dynia D, Wang T, Aronson P. NHE3 phosphorylation at serines 552 and 605 does not directly affect NHE3 activity. Am J Physiol Renal Physiol. 2007;293:F212-8 pubmed
  • 免疫细胞化学; 大鼠
  • 免疫组化; 大鼠
  • 酶联免疫吸附测定; 大鼠
  • 免疫印迹; 大鼠
  • 免疫细胞化学; primate
  • 免疫组化; primate
  • 酶联免疫吸附测定; primate
  • 免疫印迹; primate
Kocinsky H, Girardi A, Biemesderfer D, Nguyen T, Mentone S, Orlowski J, et al. Use of phospho-specific antibodies to determine the phosphorylation of endogenous Na+/H+ exchanger NHE3 at PKA consensus sites. Am J Physiol Renal Physiol. 2005;289:F249-58 pubmed
Vitzthum H, Koch M, Eckermann L, Svendsen S, Berg P, H xfc bner C, et al. The AE4 transporter mediates kidney acid-base sensing. Nat Commun. 2023;14:3051 pubmed 出版商
Klinger S. Segment-specific effects of resveratrol on porcine small intestinal dipeptide absorption depend on the mucosal pH and are due to different mechanisms: potential roles of different transport proteins and protein kinases. J Nutr Biochem. 2020;85:108467 pubmed 出版商
Koizumi M, Ueda K, Niimura F, Nishiyama A, Yanagita M, Saito A, et al. Podocyte Injury Augments Intrarenal Angiotensin II Generation and Sodium Retention in a Megalin-Dependent Manner. Hypertension. 2019;74:509-517 pubmed 出版商
Hayasaki T, Ishimoto T, Doke T, Hirayama A, Soga T, Furuhashi K, et al. Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase. J Nutr Biochem. 2019;71:54-62 pubmed 出版商
Sunilkumar S, Ford S. Elevated glucose concentration in culture media decreases membrane trafficking of SGLT2 in LLC-PK1 cells via a cAMP/PKA-dependent pathway. Am J Physiol Cell Physiol. 2019;316:C913-C924 pubmed 出版商
Masuda T, Watanabe Y, Fukuda K, Watanabe M, Onishi A, Ohara K, et al. Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat. Am J Physiol Renal Physiol. 2018;315:F653-F664 pubmed 出版商
Klinger S, Breves G. Resveratrol Inhibits Porcine Intestinal Glucose and Alanine Transport: Potential Roles of Na?/K?-ATPase Activity, Protein Kinase A, AMP-Activated Protein Kinase and the Association of Selected Nutrient Transport Proteins with Detergent Resistant Memb. Nutrients. 2018;10: pubmed 出版商
Hoesel B, Mussbacher M, Dikorman B, Salzmann M, Assinger A, Hell L, et al. Androgen receptor dampens tissue factor expression via nuclear factor-κB and early growth response protein 1. J Thromb Haemost. 2018;16:749-758 pubmed 出版商
Fenton R, Poulsen S, de la Mora Chavez S, Soleimani M, Dominguez Rieg J, Rieg T. Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis. Kidney Int. 2017;92:397-414 pubmed 出版商
Li Y, Zhang D, Lin D, Cao L. Peroxisome proliferator-activated receptor-γ inhibits pancreatic cancer cell invasion and metastasis via regulating MMP-2 expression through PTEN. Mol Med Rep. 2015;12:6255-60 pubmed 出版商
Zhang Z, Jiang T, Li Q, Wang J, Yang D, Li X, et al. Nodal activates smad and extracellular signal-regulated kinases 1/2 pathways promoting renal cell carcinoma proliferation. Mol Med Rep. 2015;12:587-94 pubmed 出版商
Füzesi Levi M, Ben Nissan G, Bianchi E, Zhou H, Deery M, Lilley K, et al. Dynamic regulation of the COP9 signalosome in response to DNA damage. Mol Cell Biol. 2014;34:1066-76 pubmed 出版商
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB110-81529
SKU号 :
NB110-81529
产品名称 :
NHE3/SLC9A3[p Ser552]抗体(14D5)
描述 :
The NHE3/SLC9A3 [p Ser552] Antibody (14D5) from Novus is a mouse monoclonal antibody to NHE3/SLC9A3. This antibody reacts with human, mouse, rat, porcine, opossum, primate, rabbit. The NHE3/SLC9A3 [p Ser552] Antibody (14D5) has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Knockout Validated, Knockdown Validated.
靶标 :
NHE3/SLC9A3
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
三羟甲基氨基甲烷甘氨酸和0.15M氯化钠
克隆性 :
单克隆
克隆 :
14D5
浓度 :
2毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Synthetic peptide made to a region surrounding the Serine 552 portion of rat NHE3. [UniProt# P26433]
抗体亚型 :
IgG2a
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠, 猪, 负鼠, 灵长类动物, 兔
特异性 :
This antibody detects NHE3 posphorylated at Serine 552, and does not cross-react with the non-phosphopeptide
理论上的分子量 :
85 kDa
基因符号 :
SLC9A3
应用 :
Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Knockout Validated, Knockdown Validated
美元 :
399美元
别名 :
isoform 3, MGC126718, NHE3MGC126720, solute carrier family 9 (sodium/hydrogen exchanger), member 3, Solute carrier family 9 member 3
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。