出版应用/物种/样本/稀释 | 参考文献 |
---|
| Yoon J, Leyva Castillo J, Wang G, Galand C, Oyoshi M, Kumar L, et al. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016;213:2147-66 pubmed 出版商
|
| Jo A, Green A, Medina J, Iyer S, Ohman A, McCarthy E, et al. Inaugurating High-Throughput Profiling of Extracellular Vesicles for Earlier Ovarian Cancer Detection. Adv Sci (Weinh). 2023;:e2301930 pubmed 出版商
|
| Jo A, Green A, Medina J, Iyer S, Ohman A, McCarthy E, et al. Profiling extracellular vesicles in circulation enables the early detection of ovarian cancer. bioRxiv. 2023;: pubmed 出版商
|
| Kanatsu Shinohara M, Lee J, Miyazaki T, Morimoto H, Shinohara T. Adeno-associated-virus-mediated gene delivery to ovaries restores fertility in congenital infertile mice. Cell Rep Med. 2022;3:100606 pubmed 出版商
|
| Hao L, Mao Y, Park J, Bae E, Park B. Repurposing the anthelmintic praziquantel to treat psoriasis. Br J Pharmacol. 2021;178:4726-4740 pubmed 出版商
|
| al Yacoub N, Colak D, Mahmoud S, Hammonds M, Muhammed K, Al Harazi O, et al. Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis. Commun Biol. 2021;4:884 pubmed 出版商
|
| Shrestha S, Adhikary G, Xu W, Kandasamy S, Eckert R. ACTL6A suppresses p21Cip1 expression to enhance the epidermal squamous cell carcinoma phenotype. Oncogene. 2020;39:5855-5866 pubmed 出版商
|
| Renema P, Kozhukhar N, Pastukh V, Spadafora D, Subedi Paudel S, Tambe D, et al. Exoenzyme Y induces extracellular active caspase-7 accumulation independent from apoptosis: Modulation of transmissible cytotoxicity. Am J Physiol Lung Cell Mol Physiol. 2020;: pubmed 出版商
|
| Lee J, Han S, Park M, Song I, Choi M, Yu E, et al. N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer's disease. Nat Commun. 2020;11:2358 pubmed 出版商
|
| Nepali K, Chang T, Lai M, Hsu K, Yen Y, Lin T, et al. Purine/purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors. Eur J Med Chem. 2020;196:112291 pubmed 出版商
|
| Wang Y, Guo S, Li D, Tang Y, Li L, Su L, et al. YIPF2 promotes chemotherapeutic agent-mediated apoptosis via enhancing TNFRSF10B recycling to plasma membrane in non-small cell lung cancer cells. Cell Death Dis. 2020;11:242 pubmed 出版商
|
| Xiao X, Sticht C, Yin L, Liu L, Karakhanova S, Yin Y, et al. Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer. Oncotarget. 2020;11:1203-1217 pubmed 出版商
|
| Lemons K, Fu Z, Ogura T, Lin W. TRPM5-expressing Microvillous Cells Regulate Region-specific Cell Proliferation and Apoptosis During Chemical Exposure. Neuroscience. 2020;434:171-190 pubmed 出版商
|
| Kanatsu Shinohara M, Chen G, Morimoto H, Shinohara T. CD2 is a surface marker for mouse and rat spermatogonial stem cells. J Reprod Dev. 2020;: pubmed 出版商
|
| de Jesus Silva S, de Moraes Silva M, Carbonel A, Grillo Filho G, Grigório T, Simões M, et al. Heparin Attenuates Visceral Apoptosis in a Swine Model of Hemorrhagic Shock and Reperfusion Injury. Ann Vasc Surg. 2020;: pubmed 出版商
|
| Wang Y, Su G, Huang Z, Wang Z, Zhou P, Fan J, et al. Cepharanthine hydrochloride induces mitophagy targeting GPR30 in hepatocellular carcinoma (HCC). Expert Opin Ther Targets. 2020;24:389-402 pubmed 出版商
|
| Lai C, Chen R, Hsieh H, Tsai S, Chang K, Yen C, et al. A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis. Cancer Lett. 2020;472:97-107 pubmed 出版商
|
| Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, et al. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nat Commun. 2019;10:5681 pubmed 出版商
|
| Ye S, Apple J, Ren X, Tang F, Yao L, Wang Y, et al. Microglial VPS35 deficiency regulates microglial polarization and decreases ischemic stroke-induced damage in the cortex. J Neuroinflammation. 2019;16:235 pubmed 出版商
|
| Wangler S, Peroglio M, Menzel U, Benneker L, Haglund L, Sakai D, et al. Mesenchymal Stem Cell Homing Into Intervertebral Discs Enhances the Tie2-positive Progenitor Cell Population, Prevents Cell Death, and Induces a Proliferative Response. Spine (Phila Pa 1976). 2019;44:1613-1622 pubmed 出版商
|
| Huang H, Liu Y, Sung T, Huang T, Cheng Y, Liou J, et al. TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis. Theranostics. 2019;9:6676-6689 pubmed 出版商
|
| Liberia T, Martín López E, Meller S, Greer C. Sequential Maturation of Olfactory Sensory Neurons in the Mature Olfactory Epithelium. Eneuro. 2019;6: pubmed 出版商
|
| Chen J, Hsieh Y, Lo H, Li A, Chou C, Yang P. In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells. Biomolecules. 2019;9: pubmed 出版商
|
| Kuthati Y, Goutham Davuluri V, Yang C, Chang H, Chang C, Wong C. Melatonin MT2 receptor agonist IIK-7 produces antinociception by modulation of ROS and suppression of spinal microglial activation in neuropathic pain rats. J Pain Res. 2019;12:2473-2485 pubmed 出版商
|
| Chang W, Wu C, Lin Y, Wu M, Su K, Yuan S, et al. C2-Ceramide-Induced Rb-Dominant Senescence-Like Phenotype Leads to Human Breast Cancer MCF-7 Escape from p53-Dependent Cell Death. Int J Mol Sci. 2019;20: pubmed 出版商
|
| Sun C, Enkhjargal B, Reis C, Zhou K, Xie Z, Wu L, et al. Osteopontin attenuates early brain injury through regulating autophagy-apoptosis interaction after subarachnoid hemorrhage in rats. CNS Neurosci Ther. 2019;25:1162-1172 pubmed 出版商
|
| Nyunt T, Britton M, Wanichthanarak K, Budamagunta M, Voss J, Wilson D, et al. Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury. Free Radic Biol Med. 2019;143:25-46 pubmed 出版商
|
| Mu N, Lei Y, Wang Y, Wang Y, Duan Q, Ma G, et al. Inhibition of SIRT1/2 upregulates HSPA5 acetylation and induces pro-survival autophagy via ATF4-DDIT4-mTORC1 axis in human lung cancer cells. Apoptosis. 2019;24:798-811 pubmed 出版商
|
| Wang Y, Su G, Huang Z, Fan J, Wang Y. Cepharanthine hydrochloride degrades polyglutamine-expanded androgen receptor proteins through an autophagy pathway in neuron cells. Eur J Pharmacol. 2019;861:172534 pubmed 出版商
|
| Akiyama N, Yamamoto Fukuda T, Yoshikawa M, Kojima H. Regulation of DNA methylation levels in the process of oral mucosal regeneration in a rat oral ulcer model. Histol Histopathol. 2019;:18147 pubmed 出版商
|
| Burgener S, Leborgne N, Snipas S, Salvesen G, Bird P, Benarafa C. Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation. Cell Rep. 2019;27:3646-3656.e5 pubmed 出版商
|
| Wu M, Chien C, Chang J, Chen Y. Pro-apoptotic effect of haem oxygenase-1 in human colorectal carcinoma cells via endoplasmic reticular stress. J Cell Mol Med. 2019;23:5692-5704 pubmed 出版商
|
| Chao M, Chang L, Tu H, Chang C, Lai M, Chen Y, et al. Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status. Clin Epigenetics. 2019;11:85 pubmed 出版商
|
| Jia R, Jia N, Yang F, Liu Z, Li R, Jiang Y, et al. Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium-Pilocarpine Model of Status Epilepticus. Cell Mol Neurobiol. 2019;39:857-869 pubmed 出版商
|
| An W, Yao S, Sun X, Hou Z, Lin Y, Su L, et al. Glucocorticoid modulatory element-binding protein 1 (GMEB1) interacts with the de-ubiquitinase USP40 to stabilize CFLARL and inhibit apoptosis in human non-small cell lung cancer cells. J Exp Clin Cancer Res. 2019;38:181 pubmed 出版商
|
| Đặng T, Ishii Y, Nguyen V, Yamamoto S, Hamashima T, Okuno N, et al. Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRα in Adult Brain. Cell Rep. 2019;27:1073-1089.e5 pubmed 出版商
|
| Owonikoko T, Zhang G, Lallani S, Chen Z, Martinson D, Khuri F, et al. Evaluation of preclinical efficacy of everolimus and pasireotide in thyroid cancer cell lines and xenograft models. PLoS ONE. 2019;14:e0206309 pubmed 出版商
|
| Chou C, Huang H, Yang C, Dahms H, Liang S, Wang T, et al. Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes. Environ Toxicol. 2019;34:401-414 pubmed 出版商
|
| Jaworski S, Strojny B, Sawosz E, Wierzbicki M, Grodzik M, Kutwin M, et al. Degradation of Mitochondria and Oxidative Stress as the Main Mechanism of Toxicity of Pristine Graphene on U87 Glioblastoma Cells and Tumors and HS-5 Cells. Int J Mol Sci. 2019;20: pubmed 出版商
|
| Li X, Song H, Kong F, Guo Y, Chen Y, Zhang L, et al. Pemetrexed exerts anticancer effects by inducing G0/G1-phase cell cycle arrest and activating the NOXA/Mcl-1 axis in human esophageal squamous cell carcinoma cells. Oncol Lett. 2019;17:1851-1858 pubmed 出版商
|
| Ponandai Srinivasan S, Lalitkumar P, Garcia L, Varghese S, Carlson J, Gemzell Danielsson K, et al. Mifepristone mediates anti-proliferative effect on ovarian mesenchymal stem/stromal cells from female BRCA1-/2- carriers. Acta Obstet Gynecol Scand. 2019;98:250-261 pubmed 出版商
|
| Fauzia E, Barbhuyan T, Shrivastava A, Kumar M, Garg P, Khan M, et al. Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism. Front Pharmacol. 2018;9:1034 pubmed 出版商
|
| Chang Y, Fong Y, Tsai E, Chang Y, Chou H, Wu C, et al. Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells. Int J Mol Sci. 2018;19: pubmed 出版商
|
| Lin W, Wang W, Lin Y, Leu J, Cheng S, Chen Y, et al. Synergistic effects of tetrandrine combined with ionizing radiation on a murine colorectal carcinoma‑bearing mouse model. Oncol Rep. 2018;40:1390-1400 pubmed 出版商
|
| Chou C, Liu W, Hong Y, Dahms H, Chiu C, Chang W, et al. Ethyl Acetate Extract of Scindapsus cf. hederaceus Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress. Int J Mol Sci. 2018;19: pubmed 出版商
|
| Krishnamoorthy V, Khanna R, Parnaik V. E3 ubiquitin ligase HECW2 targets PCNA and lamin B1. Biochim Biophys Acta Mol Cell Res. 2018;1865:1088-1104 pubmed 出版商
|
| Kanter J, Kramer F, Barnhart S, Duggan J, Shimizu Albergine M, Kothari V, et al. A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome. Diabetes. 2018;67:946-959 pubmed 出版商
|
| Zhao L, Zhu Z, Yao C, Huang Y, Zhi E, Chen H, et al. VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2. Cell Cycle. 2018;17:225-239 pubmed 出版商
|
| Qiu S, Wu X, Liao H, Zeng X, Zhang S, Lu X, et al. Pteisolic acid G, a novel ent-kaurane diterpenoid, inhibits viability and induces apoptosis in human colorectal carcinoma cells. Oncol Lett. 2017;14:5540-5548 pubmed 出版商
|
| Shinohara T, Kazuki K, Ogonuki N, Morimoto H, Matoba S, Hiramatsu K, et al. Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice. Stem Cell Reports. 2017;9:1180-1191 pubmed 出版商
|
| Shi P, Oh Y, Deng L, Zhang G, Qian G, Zhang S, et al. Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation. Clin Cancer Res. 2017;23:6567-6579 pubmed 出版商
|
| Schecher S, Walter B, Falkenstein M, Macher Goeppinger S, Stenzel P, Krümpelmann K, et al. Cyclin K dependent regulation of Aurora B affects apoptosis and proliferation by induction of mitotic catastrophe in prostate cancer. Int J Cancer. 2017;141:1643-1653 pubmed 出版商
|
| Patel N, Garikapati K, Pandita R, Singh D, Pandita T, Bhadra U, et al. miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin. Sci Rep. 2017;7:4263 pubmed 出版商
|
| Kao C, Chen W, Guo B, Feng C, Hung H, Yang W, et al. The 1-Tosylpentan-3-one Protects against 6-Hydroxydopamine-Induced Neurotoxicity. Int J Mol Sci. 2017;18: pubmed 出版商
|
| Chang W, Liu W, Chiu Y, Chen B, Chuang S, Chen Y, et al. A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression. Molecules. 2017;22: pubmed 出版商
|
| Wang Y, Chen Y, Hu S, Hsu Y, Tsai C, Chi T, et al. CYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis. Cancer Chemother Pharmacol. 2017;79:1129-1140 pubmed 出版商
|
| Chao M, Chen T, Huang H, Chang Y, HuangFu W, Lee Y, et al. Lanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells. Sci Rep. 2017;7:46134 pubmed 出版商
|
| Sakchaisri K, Kim S, Hwang J, Soung N, Lee K, Choi T, et al. Anticancer activity of a novel small molecule tubulin inhibitor STK899704. PLoS ONE. 2017;12:e0173311 pubmed 出版商
|
| Chao M, Huang H, HuangFu W, Hsu K, Liu Y, Wu Y, et al. An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells. Oncotarget. 2017;8:27772-27785 pubmed 出版商
|
| Nepali K, Lee H, Lai M, Ojha R, Wu T, Wu G, et al. Ring-opened tetrahydro-?-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms. Eur J Med Chem. 2017;127:115-127 pubmed 出版商
|
| Omar H, Tolba M, Hung J, Al Tel T. OSU-2S/Sorafenib Synergistic Antitumor Combination against Hepatocellular Carcinoma: The Role of PKC?/p53. Front Pharmacol. 2016;7:463 pubmed
|
| Huang Y, Lee C, Lee J, Liu Y, Chen Y, Tseng J, et al. Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition. Oncotarget. 2016;7:76852-76866 pubmed 出版商
|
| Liu X, Lv Z, Zou J, Liu X, Ma J, Wang J, et al. Afatinib down-regulates MCL-1 expression through the PERK-eIF2α-ATF4 axis and leads to apoptosis in head and neck squamous cell carcinoma. Am J Cancer Res. 2016;6:1708-19 pubmed
|
| Kwon J, Willy J, Quirin K, Wek R, Korc M, Yin X, et al. Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential. Oncotarget. 2016;7:71635-71650 pubmed 出版商
|
| Patel N, Garikapati K, Ramaiah M, Polavarapu K, Bhadra U, Bhadra M. miR-15a/miR-16 induces mitochondrial dependent apoptosis in breast cancer cells by suppressing oncogene BMI1. Life Sci. 2016;164:60-70 pubmed 出版商
|
| Ren H, Guo H, Thakur A, Zhang S, Wang T, Liang Y, et al. Blockade efficacy of MEK/ERK-dependent autophagy enhances PI3K/Akt inhibitor NVP-BKM120's therapeutic effectiveness in lung cancer cells. Oncotarget. 2016;7:67277-67287 pubmed 出版商
|
| Huang S, Lien J, Chen C, Liu Y, Wang C, Ping C, et al. Antiviral Activity of a Novel Compound CW-33 against Japanese Encephalitis Virus through Inhibiting Intracellular Calcium Overload. Int J Mol Sci. 2016;17: pubmed 出版商
|
| Huang H, Chao M, Li Y, Chang L, Chen C, Chen M, et al. MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer. Sci Rep. 2016;6:31664 pubmed 出版商
|
| Huang X, Huang R, Gou S, Wang Z, Liao Z, Wang H. Combretastatin A-4 Analogue: A Dual-Targeting and Tubulin Inhibitor Containing Antitumor Pt(IV) Moiety with a Unique Mode of Action. Bioconjug Chem. 2016;27:2132-48 pubmed 出版商
|
| Shi P, Oh Y, Zhang G, Yao W, Yue P, Li Y, et al. Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment. Cancer Lett. 2016;380:494-504 pubmed 出版商
|
| Repsold L, Pretorius E, Joubert A. Ex vivo apoptotic and autophagic influence of an estradiol analogue on platelets. Exp Hematol Oncol. 2015;5:18 pubmed 出版商
|
| Chen N, Chyau C, Lee Y, Tseng H, Chou F. Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells. Sci Rep. 2016;6:20417 pubmed 出版商
|
| Lai Y, Chuang Y, Chang C, Yeh T. Macrophage migration inhibitory factor has a permissive role in concanavalin A-induced cell death of human hepatoma cells through autophagy. Cell Death Dis. 2015;6:e2008 pubmed 出版商
|
| Han C, Chiang H, Lin C, Tang C, Lee H, Huang D, et al. Comparison of Immunomodulatory and Anticancer Activities in Different Strains of Tremella fuciformis Berk. Am J Chin Med. 2015;43:1637-55 pubmed 出版商
|
| Oliver Metzig M, Fuchs D, Tagscherer K, Gröne H, Schirmacher P, Roth W. Inhibition of caspases primes colon cancer cells for 5-fluorouracil-induced TNF-α-dependent necroptosis driven by RIP1 kinase and NF-κB. Oncogene. 2016;35:3399-409 pubmed 出版商
|
| Fassl A, Tagscherer K, Richter J, De Castro Arce J, Savini C, Rösl F, et al. Inhibition of Notch1 signaling overcomes resistance to the death ligand Trail by specificity protein 1-dependent upregulation of death receptor 5. Cell Death Dis. 2015;6:e1921 pubmed 出版商
|
| Liu X, Guo S, Liu X, Su L. Chaetocin induces endoplasmic reticulum stress response and leads to death receptor 5-dependent apoptosis in human non-small cell lung cancer cells. Apoptosis. 2015;20:1499-507 pubmed 出版商
|
| Ge G, Xia H, He B, Zhang H, Liu W, Shao M, et al. Generation and characterization of a breast carcinoma model by PyMT overexpression in mammary epithelial cells of tree shrew, an animal close to primates in evolution. Int J Cancer. 2016;138:642-51 pubmed 出版商
|
| Liou J, Teng M, Tsai Y, Lin E, Chen B. UV-blocking spectacle lens protects against UV-induced decline of visual performance. Mol Vis. 2015;21:846-56 pubmed
|
| Gkouskou K, Ioannou M, Pavlopoulos G, Georgila K, Siganou A, Nikolaidis G, et al. Apolipoprotein A-I inhibits experimental colitis and colitis-propelled carcinogenesis. Oncogene. 2016;35:2496-505 pubmed 出版商
|
| He S, Zhao Z, Yang Y, O Connell D, Zhang X, Oh S, et al. Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers. Nat Commun. 2015;6:7839 pubmed 出版商
|
| Lu J, Lin Y, Lai Y, Chen C, Hu C, Tien H, et al. MK-2206 induces apoptosis of AML cells and enhances the cytotoxicity of cytarabine. Med Oncol. 2015;32:206 pubmed 出版商
|
| Rodriguez M, Siwko S, Zeng L, Li J, Yi Z, Liu M. Prostate-specific G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression. Oncogene. 2016;35:1153-62 pubmed 出版商
|
| Li J, Sharkey C, King M. Piperlongumine and immune cytokine TRAIL synergize to promote tumor death. Sci Rep. 2015;5:9987 pubmed 出版商
|
| Jaworski S, Sawosz E, Kutwin M, Wierzbicki M, Hinzmann M, Grodzik M, et al. In vitro and in vivo effects of graphene oxide and reduced graphene oxide on glioblastoma. Int J Nanomedicine. 2015;10:1585-96 pubmed 出版商
|
| Talaber G, Tuckermann J, Okret S. ACTH controls thymocyte homeostasis independent of glucocorticoids. FASEB J. 2015;29:2526-34 pubmed 出版商
|
| Kato S, Hayashi S, Kitahara Y, Nagasawa K, Aono H, Shibata J, et al. Saireito (TJ-114), a Japanese traditional herbal medicine, reduces 5-fluorouracil-induced intestinal mucositis in mice by inhibiting cytokine-mediated apoptosis in intestinal crypt cells. PLoS ONE. 2015;10:e0116213 pubmed 出版商
|
| Roobol A, Roobol J, Bastide A, Knight J, Willis A, Smales C. p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity. Biochem J. 2015;465:213-25 pubmed 出版商
|
| Liu T, Lo H, Wei L, Hsiao H, Yang P. S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells. Anticancer Drugs. 2015;26:139-47 pubmed 出版商
|
| Owonikoko T, Zhang G, Deng X, Rossi M, Switchenko J, Doho G, et al. Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer. Cancer Med. 2014;3:1579-94 pubmed 出版商
|
| Xia M, Meng G, Jiang A, Chen A, Dahlhaus M, Gonzalez P, et al. Mitophagy switches cell death from apoptosis to necrosis in NSCLC cells treated with oncolytic measles virus. Oncotarget. 2014;5:3907-18 pubmed
|
| Yan J, Zhong N, Liu G, Chen K, Liu X, Su L, et al. Usp9x- and Noxa-mediated Mcl-1 downregulation contributes to pemetrexed-induced apoptosis in human non-small-cell lung cancer cells. Cell Death Dis. 2014;5:e1316 pubmed 出版商
|
| Tsai A, Wang C, Liou J, Pai H, Hsiao C, Chang J, et al. Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib. Cell Death Dis. 2014;5:e1162 pubmed 出版商
|
| Yi L, Zongyuan Y, Cheng G, Lingyun Z, Guilian Y, Wei G. Quercetin enhances apoptotic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer-binding protein homologous protein (CHOP)-death receptor 5 pa. Cancer Sci. 2014;105:520-7 pubmed 出版商
|
| Lin W, Tsai H, Liao H, Tang C, Wu Y, Hsu P, et al. Helicobacter pylori sensitizes TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human gastric epithelial cells through regulation of FLIP. Cell Death Dis. 2014;5:e1109 pubmed 出版商
|
| Chen C, Chen M, Wang J, Tsai A, Chen C, Liou J, et al. Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo. Clin Cancer Res. 2014;20:1274-1287 pubmed 出版商
|
| Mukherjee S, Chowdhury D, Kotcherlakota R, Patra S, B V, Bhadra M, et al. Potential theranostics application of bio-synthesized silver nanoparticles (4-in-1 system). Theranostics. 2014;4:316-35 pubmed 出版商
|
| Wang H, Lewsadder M, Dorn E, Xu S, Lakshmana M. RanBP9 overexpression reduces dendritic arbor and spine density. Neuroscience. 2014;265:253-62 pubmed 出版商
|
| Galvez Contreras A, Gonzalez Castañeda R, Luquin S, Guzmán Muñiz J, Moy Lopez N, Ramos Zúñiga R, et al. Diphenylhydantoin promotes proliferation in the subventricular zone and dentate gyrus. Am J Neurosci. 2012;3:1-9 pubmed
|
| Zhao X, Liu X, Su L. Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells. J Exp Clin Cancer Res. 2014;33:3 pubmed 出版商
|
| Paul S, Kundu R. Antiproliferative activity of methanolic extracts from two green algae, Enteromorpha intestinalis and Rizoclonium riparium on HeLa cells. Daru. 2013;21:72 pubmed 出版商
|
| Aulakh G, Balachandran Y, Liu L, Singh B. Angiostatin inhibits activation and migration of neutrophils. Cell Tissue Res. 2014;355:375-96 pubmed 出版商
|
| Hristova N, Tagscherer K, Fassl A, Kopitz J, Roth W. Notch1-dependent regulation of p27 determines cell fate in colorectal cancer. Int J Oncol. 2013;43:1967-75 pubmed 出版商
|
| Tsai A, Pai H, Wang C, Liou J, Teng C, Wang J, et al. In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells. Br J Pharmacol. 2014;171:122-33 pubmed 出版商
|
| Weissinger D, Tagscherer K, Macher Göppinger S, Haferkamp A, Wagener N, Roth W. The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma. Mol Cancer. 2013;12:120 pubmed 出版商
|
| Kant S, Kumar A, Singh S. Tumor growth retardation and chemosensitizing action of fatty acid synthase inhibitor orlistat on T cell lymphoma: implication of reconstituted tumor microenvironment and multidrug resistance phenotype. Biochim Biophys Acta. 2014;1840:294-302 pubmed 出版商
|
| Huang C, Yang C, Jeng Y, Chen C, Wu H, Chang Y, et al. Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-?B-mediated antiapoptotic pathway. Oncogene. 2014;33:2968-77 pubmed 出版商
|
| Palavicini J, Lloyd B, Hayes C, Bianchi E, Kang D, Dawson Scully K, et al. RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice. PLoS ONE. 2013;8:e66908 pubmed 出版商
|
| Wallace M, Russell A. Striated muscle activator of Rho signaling is required for myotube survival but does not influence basal protein synthesis or degradation. Am J Physiol Cell Physiol. 2013;305:C414-26 pubmed 出版商
|
| Chiu C, Haung J, Chang F, Huang K, Huang H, Huang H, et al. Golden berry-derived 4?-hydroxywithanolide E for selectively killing oral cancer cells by generating ROS, DNA damage, and apoptotic pathways. PLoS ONE. 2013;8:e64739 pubmed 出版商
|
| Saha T. LAMP2A overexpression in breast tumors promotes cancer cell survival via chaperone-mediated autophagy. Autophagy. 2012;8:1643-56 pubmed 出版商
|
| Hossain A, Radwan F, Doonan B, God J, Zhang L, Bell P, et al. A possible cross-talk between autophagy and apoptosis in generating an immune response in melanoma. Apoptosis. 2012;17:1066-78 pubmed 出版商
|
| Schultz C, Golembieski W, King D, Brown S, Brodie C, Rempel S. Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival. Mol Cancer. 2012;11:20 pubmed 出版商
|
| Tagscherer K, Fassl A, Sinkovic T, Combs S, Roth W. p53-dependent regulation of Mcl-1 contributes to synergistic cell death by ionizing radiation and the Bcl-2/Bcl-XL inhibitor ABT-737. Apoptosis. 2012;17:187-99 pubmed 出版商
|
| Gonzalez Perez O, Chavez Casillas O, Jauregui Huerta F, Lopez Virgen V, Guzmán Muñiz J, Moy Lopez N, et al. Stress by noise produces differential effects on the proliferation rate of radial astrocytes and survival of neuroblasts in the adult subgranular zone. Neurosci Res. 2011;70:243-50 pubmed 出版商
|
| Xu D, Meyer F, Ehlers E, Blasnitz L, Zhang L. Interferon regulatory factor 4 (IRF-4) targets IRF-5 to regulate Epstein-Barr virus transformation. J Biol Chem. 2011;286:18261-7 pubmed 出版商
|
| Singer M, Trugnan G, Chelbi Alix M. Arsenic trioxide reduces 2,4,6-trinitrobenzene sulfonic acid-induced murine colitis via nuclear factor-?B down-regulation and caspase-3 activation. Innate Immun. 2011;17:365-74 pubmed 出版商
|
| Spassov A, Gredes T, Gedrange T, Pavlovic D, Lupp A, Kunert Keil C. Increased oxidative stress in dystrophin deficient (mdx) mice masticatory muscles. Exp Toxicol Pathol. 2011;63:549-52 pubmed 出版商
|
| Fernandez K, Serinagaoglu Y, Hammond S, Martin L, Martin P. Mice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts. Am J Pathol. 2010;176:416-34 pubmed 出版商
|
| Tsai A, Pan S, Sun H, Wang C, Peng C, Wang S, et al. CHM-1, a new vascular targeting agent, induces apoptosis of human umbilical vein endothelial cells via p53-mediated death receptor 5 up-regulation. J Biol Chem. 2010;285:5497-506 pubmed 出版商
|
| Joy B, Sivadasan R, Abraham T E, John M, Sobhan P, Seervi M, et al. Lysosomal destabilization and cathepsin B contributes for cytochrome c release and caspase activation in embelin-induced apoptosis. Mol Carcinog. 2010;49:324-36 pubmed 出版商
|
| Temime Smaali N, Guittat L, Sidibe A, Shin ya K, Trentesaux C, Riou J. The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells. PLoS ONE. 2009;4:e6919 pubmed 出版商
|
| Chopra B, Georgopoulos N, Nicholl A, Hinley J, Oleksiewicz M, Southgate J. Structurally diverse peroxisome proliferator-activated receptor agonists induce apoptosis in human uro-epithelial cells by a receptor-independent mechanism involving store-operated calcium channels. Cell Prolif. 2009;42:688-700 pubmed 出版商
|
| Kaneko Y, Nakashima A, Mori K, Nagatsu T, Nagatsu I, Ota A. Lipopolysaccharide extends the lifespan of mouse primary-cultured microglia. Brain Res. 2009;1279:9-20 pubmed 出版商
|
| Louneva N, Cohen J, Han L, Talbot K, Wilson R, Bennett D, et al. Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease. Am J Pathol. 2008;173:1488-95 pubmed 出版商
|
| Zou W, Yue P, Khuri F, Sun S. Coupling of endoplasmic reticulum stress to CDDO-Me-induced up-regulation of death receptor 5 via a CHOP-dependent mechanism involving JNK activation. Cancer Res. 2008;68:7484-92 pubmed 出版商
|
| Ray P, De A, Patel M, Gambhir S. Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects. Clin Cancer Res. 2008;14:5801-9 pubmed 出版商
|
| Hsiao C, Ho Y, Hsu J, Chang W, Chen Y, Shen Y, et al. Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress. Naunyn Schmiedebergs Arch Pharmacol. 2008;378:599-608 pubmed 出版商
|
| Raja S, Chen S, Yue P, Acker T, Lefkove B, Arbiser J, et al. The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. Mol Cancer Ther. 2008;7:2212-23 pubmed 出版商
|
| Chen T, Pan S, Guh J, Chen C, Huang Y, Pai H, et al. Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. Naunyn Schmiedebergs Arch Pharmacol. 2008;378:447-57 pubmed 出版商
|
| Chen T, Pan S, Guh J, Liao C, Huang D, Chen C, et al. Moscatilin induces apoptosis in human colorectal cancer cells: a crucial role of c-Jun NH2-terminal protein kinase activation caused by tubulin depolymerization and DNA damage. Clin Cancer Res. 2008;14:4250-8 pubmed 出版商
|
| Lin Y, Chen S, Yue P, Zou W, Benbrook D, Liu S, et al. CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells. Cancer Res. 2008;68:5335-44 pubmed 出版商
|
| Yui S, Kanamoto R, Saeki T. Deoxycholic acid can induce apoptosis in the human colon cancer cell line HCT116 in the absence of Bax. Nutr Cancer. 2008;60:91-6 pubmed 出版商
|
| Campo G, Avenoso A, Campo S, Nastasi G, Traina P, D Ascola A, et al. Chondroitin-4-sulphate reduced oxidative injury in caerulein-induced pancreatitis in mice: the involvement of NF-kappaB translocation and apoptosis activation. Exp Biol Med (Maywood). 2008;233:741-52 pubmed 出版商
|
| Liu C, Erlichman C, McDonald C, Ingle J, Zollman P, Iankov I, et al. Heat shock protein inhibitors increase the efficacy of measles virotherapy. Gene Ther. 2008;15:1024-34 pubmed 出版商
|
| Wang S, Pan S, Huang Y, Guh J, Chiang P, Huang D, et al. CHM-1, a novel synthetic quinolone with potent and selective antimitotic antitumor activity against human hepatocellular carcinoma in vitro and in vivo. Mol Cancer Ther. 2008;7:350-60 pubmed 出版商
|
| Gdynia G, Lehmann Koch J, Sieber S, Tagscherer K, Fassl A, Zentgraf H, et al. BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis. Apoptosis. 2008;13:437-47 pubmed 出版商
|
| Lee A, Su M. Comparison of the cardiac effects between quinazoline-based alpha1-adrenoceptor antagonists on occlusion-reperfusion injury. J Biomed Sci. 2008;15:239-49 pubmed
|
| Shuvaev V, Tliba S, Nakada M, Albelda S, Muzykantov V. Platelet-endothelial cell adhesion molecule-1-directed endothelial targeting of superoxide dismutase alleviates oxidative stress caused by either extracellular or intracellular superoxide. J Pharmacol Exp Ther. 2007;323:450-7 pubmed
|
| Lee H, Cho S, Lee H, Kim M, Kim J, Park D, et al. Protein expression profiling and molecular classification of gastric cancer by the tissue array method. Clin Cancer Res. 2007;13:4154-63 pubmed
|
| Elrod H, Lin Y, Yue P, Wang X, Lonial S, Khuri F, et al. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway. Mol Cancer Ther. 2007;6:2029-38 pubmed
|
| Li J, Yang J. Cyclin B1 proteolysis via p38 MAPK signaling participates in G2 checkpoint elicited by arsenite. J Cell Physiol. 2007;212:481-8 pubmed
|
| Eiselein L, Wilson D, Lame M, Rutledge J. Lipolysis products from triglyceride-rich lipoproteins increase endothelial permeability, perturb zonula occludens-1 and F-actin, and induce apoptosis. Am J Physiol Heart Circ Physiol. 2007;292:H2745-53 pubmed
|
| Kumar M, Nair M, Hema P, Mohan J, Santhoshkumar T. Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells. Mol Carcinog. 2007;46:231-41 pubmed
|
| Chiou S, Yang Y, Lin J, Hsu C, Jhang H, Yang Y, et al. The immediate early 2 protein of human cytomegalovirus (HCMV) mediates the apoptotic control in HCMV retinitis through up-regulation of the cellular FLICE-inhibitory protein expression. J Immunol. 2006;177:6199-206 pubmed
|
| Schultze K, Böck B, Eckert A, Oevermann L, Ramacher D, Wiestler O, et al. Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin. Apoptosis. 2006;11:1503-12 pubmed
|
| Chiang P, Kung F, Huang D, Li T, Fan J, Pan S, et al. Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells. Eur J Pharmacol. 2006;542:22-30 pubmed
|
| Jarskog L, Gilmore J, Glantz L, Gable K, German T, Tong R, et al. Caspase-3 activation in rat frontal cortex following treatment with typical and atypical antipsychotics. Neuropsychopharmacology. 2007;32:95-102 pubmed
|
| Mohan J, Gandhi A, Bhavya B, Rashmi R, Karunagaran D, Indu R, et al. Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol. J Biol Chem. 2006;281:17599-611 pubmed
|
| Huang Y, Pan S, Guh J, Chang Y, Lee F, Kuo S, et al. YC-1 suppresses constitutive nuclear factor-kappaB activation and induces apoptosis in human prostate cancer cells. Mol Cancer Ther. 2005;4:1628-35 pubmed
|
| Jian W, Arora J, Oe T, Shuvaev V, Blair I. Induction of endothelial cell apoptosis by lipid hydroperoxide-derived bifunctional electrophiles. Free Radic Biol Med. 2005;39:1162-76 pubmed
|
| Jin F, Liu X, Zhou Z, Yue P, Lotan R, Khuri F, et al. Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells. Cancer Res. 2005;65:6354-63 pubmed
|
| Chiang P, Chien C, Pan S, Chen W, Teng C, Shen Y, et al. Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma. J Hepatol. 2005;43:679-86 pubmed
|
| Hylander B, Pitoniak R, Penetrante R, Gibbs J, Oktay D, Cheng J, et al. The anti-tumor effect of Apo2L/TRAIL on patient pancreatic adenocarcinomas grown as xenografts in SCID mice. J Transl Med. 2005;3:22 pubmed
|
| Lee J, Lee C, Su C, Huang C, Liu H, Lin C, et al. Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells. Carcinogenesis. 2005;26:1716-30 pubmed
|
| Douarre C, Gomez D, Morjani H, Zahm J, O Donohue M, Eddabra L, et al. Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence. Nucleic Acids Res. 2005;33:2192-203 pubmed
|
| Tang C, Hu C, Wei C, Wang J. Synergism of Rana catesbeiana ribonuclease and IFN-gamma triggers distinct death machineries in different human cancer cells. FEBS Lett. 2005;579:265-70 pubmed
|
| Ko C, Shen S, Chen Y. Hydroxylation at C4' or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species. Free Radic Biol Med. 2004;36:897-910 pubmed
|
| Wu Y, Shih S, Lin J. Ricin triggers apoptotic morphological changes through caspase-3 cleavage of BAT3. J Biol Chem. 2004;279:19264-75 pubmed
|
| Jarskog L, Selinger E, Lieberman J, Gilmore J. Apoptotic proteins in the temporal cortex in schizophrenia: high Bax/Bcl-2 ratio without caspase-3 activation. Am J Psychiatry. 2004;161:109-15 pubmed
|
| Lin H, Lui W, Liu T, Chi C. Reversal of Taxol resistance in hepatoma by cyclosporin A: involvement of the PI-3 kinase-AKT 1 pathway. Br J Cancer. 2003;88:973-80 pubmed
|
| Kim K, Lotan R, Yue P, Sporn M, Suh N, Gribble G, et al. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells. Mol Cancer Ther. 2002;1:177-84 pubmed
|
| Chen Y, Shen S, Lee W, Hsu F, Lin H, Ko C, et al. Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production. Biochem Pharmacol. 2002;64:1713-24 pubmed
|
| Zhang W, Sato K, Iwai M, Nagano I, Manabe Y, Abe K. Therapeutic time window of adenovirus-mediated GDNF gene transfer after transient middle cerebral artery occlusion in rat. Brain Res. 2002;947:140-5 pubmed
|
| Sun S, Yue P, Chen X, Hong W, Lotan R. The synthetic retinoid CD437 selectively induces apoptosis in human lung cancer cells while sparing normal human lung epithelial cells. Cancer Res. 2002;62:2430-6 pubmed
|
| Yamaguchi H, Paranawithana S, Lee M, Huang Z, Bhalla K, Wang H. Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells. Cancer Res. 2002;62:466-71 pubmed
|
| Yamaguchi H, Wang H. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change. Oncogene. 2001;20:7779-86 pubmed
|
| Sun S, Yue P, Kelloff G, Steele V, Lippman S, Hong W, et al. Identification of retinamides that are more potent than N-(4-hydroxyphenyl)retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells. Cancer Epidemiol Biomarkers Prev. 2001;10:595-601 pubmed
|
| Cuddeback S, Yamaguchi H, Komatsu K, Miyashita T, Yamada M, Wu C, et al. Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J Biol Chem. 2001;276:20559-65 pubmed
|