| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Xia L, Huang W, Bellani M, Seidman M, Wu K, Fan D, et al. CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes. Cancer Cell. 2017;31:653-668.e7 pubmed 出版商 |
| Mulholland C, Smets M, Schmidtmann E, Leidescher S, Markaki Y, Hofweber M, et al. A modular open platform for systematic functional studies under physiological conditions. Nucleic Acids Res. 2015;43:e112 pubmed 出版商 |
| Robaina M, Mazzoccoli L, Arruda V, Reis F, Apa A, de Rezende L, et al. Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis. Exp Mol Pathol. 2015;98:200-7 pubmed 出版商 |
| Neri F, Incarnato D, Krepelova A, Rapelli S, Anselmi F, Parlato C, et al. Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals Promoter DNA Methylation Dynamics. Cell Rep. 2015;10:674-683 pubmed 出版商 |
| Guo Y, Shu L, Zhang C, Su Z, Kong A. Curcumin inhibits anchorage-independent growth of HT29 human colon cancer cells by targeting epigenetic restoration of the tumor suppressor gene DLEC1. Biochem Pharmacol. 2015;94:69-78 pubmed 出版商 |
| Huichalaf C, Micheloni S, Ferri G, Caccia R, Gabellini D. DNA methylation analysis of the macrosatellite repeat associated with FSHD muscular dystrophy at single nucleotide level. PLoS ONE. 2014;9:e115278 pubmed 出版商 |
| Wang L, Zhang C, Guo Y, Su Z, Yang Y, Shu L, et al. Blocking of JB6 cell transformation by tanshinone IIA: epigenetic reactivation of Nrf2 antioxidative stress pathway. AAPS J. 2014;16:1214-25 pubmed 出版商 |
| Guimarães D, Antunes D, Duarte C, Ferro L, Nunes F. DNA methyltransferase immunohistochemical expression in odontogenic tumours. J Oral Pathol Med. 2015;44:59-66 pubmed 出版商 |
| Paredes Gonzalez X, Fuentes F, Su Z, Kong A. Apigenin reactivates Nrf2 anti-oxidative stress signaling in mouse skin epidermal JB6 P + cells through epigenetics modifications. AAPS J. 2014;16:727-35 pubmed 出版商 |
| Hara S, Takano T, Ogata M, Yamakami R, Sato Y, Kono T, et al. Establishment of a conditional transgenic system using the 2A peptide in the female mouse germline. J Reprod Dev. 2014;60:250-5 pubmed |
| Serra R, Fang M, Park S, Hutchinson L, Green M. A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype. elife. 2014;3:e02313 pubmed 出版商 |
| Hara S, Takano T, Fujikawa T, Yamada M, Wakai T, Kono T, et al. Forced expression of DNA methyltransferases during oocyte growth accelerates the establishment of methylation imprints but not functional genomic imprinting. Hum Mol Genet. 2014;23:3853-64 pubmed 出版商 |
| Hara E, Ono M, Eguchi T, Kubota S, Pham H, Sonoyama W, et al. miRNA-720 controls stem cell phenotype, proliferation and differentiation of human dental pulp cells. PLoS ONE. 2013;8:e83545 pubmed 出版商 |
| Wongtrakoongate P, Li J, Andrews P. DNMT3B inhibits the re-expression of genes associated with induced pluripotency. Exp Cell Res. 2014;321:231-9 pubmed 出版商 |
| Zhou J, Dhawan S, Fu H, Snyder E, Bottino R, Kundu S, et al. Combined modulation of polycomb and trithorax genes rejuvenates ? cell replication. J Clin Invest. 2013;123:4849-58 pubmed |
| Obata Y, Wakai T, Hara S, Kono T. Long exposure to mature ooplasm can alter DNA methylation at imprinted loci in non-growing oocytes but not in prospermatogonia. Reproduction. 2014;147:H1-6 pubmed 出版商 |
| Kadriu B, Guidotti A, Chen Y, Grayson D. DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67-positive neurons in the GAD67-GFP mouse brain. J Comp Neurol. 2012;520:1951-64 pubmed 出版商 |
| Yang J, Wei X, Wu Q, Xu Z, Gu D, Jin Y, et al. Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer. Mol Med Rep. 2011;4:1139-43 pubmed 出版商 |
| Molognoni F, Cruz A, Meliso F, Morais A, Souza C, Xander P, et al. Epigenetic reprogramming as a key contributor to melanocyte malignant transformation. Epigenetics. 2011;6:450-64 pubmed |
| Lahousse S, Hoenerhoff M, Collins J, Ton T, Masinde T, Olson D, et al. Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice. Vet Pathol. 2011;48:875-84 pubmed 出版商 |
| Lambrot R, Kimmins S. Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines. Int J Androl. 2011;34:110-23 pubmed 出版商 |
| May A, Kirchner R, Muller H, Hartmann P, El Hajj N, Tresch A, et al. Multiplex rt-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeres. Biol Reprod. 2009;80:194-202 pubmed 出版商 |
| Hirasawa R, Chiba H, Kaneda M, Tajima S, Li E, Jaenisch R, et al. Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes Dev. 2008;22:1607-16 pubmed 出版商 |
| Xia G, Schneider Stock R, Diestel A, Habold C, Krueger S, Roessner A, et al. Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation. Biochem Biophys Res Commun. 2008;369:526-31 pubmed 出版商 |
| Linhart H, Lin H, Yamada Y, Moran E, Steine E, Gokhale S, et al. Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes Dev. 2007;21:3110-22 pubmed |
| Lucifero D, La Salle S, Bourc his D, Martel J, Bestor T, Trasler J. Coordinate regulation of DNA methyltransferase expression during oogenesis. BMC Dev Biol. 2007;7:36 pubmed |
| La Salle S, Trasler J. Dynamic expression of DNMT3a and DNMT3b isoforms during male germ cell development in the mouse. Dev Biol. 2006;296:71-82 pubmed |
| Chen T, Ueda Y, Dodge J, Wang Z, Li E. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol. 2003;23:5594-605 pubmed |
| Ren G, Li H, Hong D, Hu F, Jin R, Wu S, et al. LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter. BMC Cancer. 2023;23:898 pubmed 出版商 |
| Fernandes C, da Silva R, Wood P, Ferreira M, de Almeida G, de Moraes J, et al. Titanium-Enriched Medium Promotes Environment-Induced Epigenetic Machinery Changes in Human Endothelial Cells. J Funct Biomater. 2023;14: pubmed 出版商 |
| da C Fernandes C, da Silva R, de Almeida G, Ferreira M, de Morais P, Bezerra F, et al. Epigenetic Differences Arise in Endothelial Cells Responding to Cobalt-Chromium. J Funct Biomater. 2023;14: pubmed 出版商 |
| Narabayashi H, Koma C, Nakata K, Ikegami M, Nakanishi Y, Ogihara J, et al. Gut microbiota-dependent adaptor molecule recruits DNA methyltransferase to the TLR4 gene in colonic epithelial cells to suppress inflammatory reactions. Front Mol Biosci. 2022;9:1005136 pubmed 出版商 |
| Ni Q, Sun J, Wang Y, Wang Y, Liu J, Ning G, et al. mTORC1 is required for epigenetic silencing during β-cell functional maturation. Mol Metab. 2022;64:101559 pubmed 出版商 |
| Lu F, Zankharia U, Vladimirova O, Yi Y, Collman R, Lieberman P. Epigenetic Landscape of HIV-1 Infection in Primary Human Macrophage. J Virol. 2022;96:e0016222 pubmed 出版商 |
| Zhao J, Lin H, Huang K. Mesenchymal Stem Cell-derived Extracellular Vesicles Transmitting MicroRNA-34a-5p Suppress Tumorigenesis of Colorectal Cancer Through c-MYC/DNMT3a/PTEN Axis. Mol Neurobiol. 2022;59:47-60 pubmed 出版商 |
| Liu X, Cui H. The palliative effects of folic acid on retinal microvessels in diabetic retinopathy via regulating the metabolism of DNA methylation and hydroxymethylation. Bioengineered. 2021;12:10766-10774 pubmed 出版商 |
| Aronson B, Scourzic L, Shah V, Swanzey E, Kloetgen A, Polyzos A, et al. A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus. Dev Cell. 2021;56:3052-3065.e5 pubmed 出版商 |
| da C Fernandes C, da Silva R, Fretes Wood P, Teixeira S, Bezerra F, Zambuzzi W. The molecular pathway triggered by zirconia in endothelial cells involves epigenetic control. Tissue Cell. 2021;73:101627 pubmed 出版商 |
| Kim K, Li C, Bunina D, Jeong H, Ghelman J, Yoon J, et al. Donor cell memory confers a metastable state of directly converted cells. Cell Stem Cell. 2021;28:1291-1306.e10 pubmed 出版商 |
| Huang Z, Yu J, Cui W, Johnson B, Kim K, Pfeifer G. The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins. Sci Adv. 2021;7: pubmed 出版商 |
| Broche J, Kungulovski G, Bashtrykov P, Rathert P, Jeltsch A. Genome-wide investigation of the dynamic changes of epigenome modifications after global DNA methylation editing. Nucleic Acids Res. 2021;49:158-176 pubmed 出版商 |
| Wei J, Cheng J, Waddell N, Wang Z, Pang X, Cao Q, et al. DNA Methyltransferase 3A Is Involved in the Sustained Effects of Chronic Stress on Synaptic Functions and Behaviors. Cereb Cortex. 2021;31:1998-2012 pubmed 出版商 |
| Cárdenas H, Fang F, Jiang G, Perkins S, Zhang C, Emerson R, et al. Methylomic Signatures of High Grade Serous Ovarian Cancer. Epigenetics. 2020;:1-16 pubmed 出版商 |
| Zaro B, Noh J, Mascetti V, Demeter J, George B, Zukowska M, et al. Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells. elife. 2020;9: pubmed 出版商 |
| Jia Y, Xie H, Zhang J, Ying H. Induction of TGF-β receptor I expression in a DNA methylation-independent manner mediated by DNMT3A downregulation is involved in early-onset severe preeclampsia. FASEB J. 2020;34:13224-13238 pubmed 出版商 |
| Magno Guimarães D, deLucas da Silva Almeida F, Moraes Castilho R, Eduardo Nor J, Daumas Nunes F. DNA methyltransferase expression is associated with cell proliferation in salivary mucoepidermoid carcinoma. J Oral Pathol Med. 2020;49:1053-1060 pubmed 出版商 |
| Yagi M, Kabata M, Tanaka A, Ukai T, Ohta S, Nakabayashi K, et al. Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development. Nat Commun. 2020;11:3199 pubmed 出版商 |
| Dahlet T, Argüeso Lleida A, Al Adhami H, Dumas M, Bender A, Ngondo R, et al. Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity. Nat Commun. 2020;11:3153 pubmed 出版商 |
| Ginno P, Gaidatzis D, Feldmann A, Hoerner L, Imanci D, Burger L, et al. A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity. Nat Commun. 2020;11:2680 pubmed 出版商 |
| McAninch D, Mäkelä J, La H, Hughes J, Lovell Badge R, Hobbs R, et al. SOX3 promotes generation of committed spermatogonia in postnatal mouse testes. Sci Rep. 2020;10:6751 pubmed 出版商 |
| Lavery L, Ure K, Wan Y, Luo C, Trostle A, Wang W, et al. Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome. elife. 2020;9: pubmed 出版商 |
| Ravichandran M, Lei R, Tang Q, Zhao Y, Lee J, Ma L, et al. Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells. Cell Rep. 2019;28:1993-2003.e5 pubmed 出版商 |
| Kong X, Chen J, Xie W, Brown S, Cai Y, Wu K, et al. Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties. Cancer Cell. 2019;35:633-648.e7 pubmed 出版商 |
| Heyn P, Logan C, Fluteau A, Challis R, Auchynnikava T, Martin C, et al. Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions. Nat Genet. 2019;51:96-105 pubmed 出版商 |
| van Mierlo G, Dirks R, De Clerck L, Brinkman A, Huth M, Kloet S, et al. Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency. Cell Stem Cell. 2019;24:123-137.e8 pubmed 出版商 |
| Cyphert H, Walker E, Hang Y, Dhawan S, Haliyur R, Bonatakis L, et al. Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally. Diabetes. 2019;68:337-348 pubmed 出版商 |
| Pang Y, Liu J, Li X, Xiao G, Wang H, Yang G, et al. MYC and DNMT3A-mediated DNA methylation represses microRNA-200b in triple negative breast cancer. J Cell Mol Med. 2018;22:6262-6274 pubmed 出版商 |
| Chatterjee B, Lin M, Chen C, Peng K, Wu M, Tseng M, et al. DNA Demethylation by DNMT3A and DNMT3B in vitro and of Methylated Episomal DNA in Transiently Transfected Cells. Biochim Biophys Acta Gene Regul Mech. 2018;1861:1048-1061 pubmed 出版商 |
| Sheikh M, Malik Y, Zhu X. RA-Induced Transcriptional Silencing of Checkpoint Kinase-2 through Promoter Methylation by Dnmt3b Is Required for Neuronal Differentiation of P19 Cells. J Mol Biol. 2017;429:2463-2473 pubmed 出版商 |
| Ni Q, Gu Y, Xie Y, Yin Q, Zhang H, Nie A, et al. Raptor regulates functional maturation of murine beta cells. Nat Commun. 2017;8:15755 pubmed 出版商 |
| Mahadevan S, Sathappan V, Utama B, Lorenzo I, Kaskar K, Van den Veyver I. Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming. Sci Rep. 2017;7:44667 pubmed 出版商 |
| Neri F, Rapelli S, Krepelova A, Incarnato D, Parlato C, Basile G, et al. Intragenic DNA methylation prevents spurious transcription initiation. Nature. 2017;543:72-77 pubmed 出版商 |
| Acharya M, Baddour A, Kawashita T, Allen B, Syage A, Nguyen T, et al. Epigenetic determinants of space radiation-induced cognitive dysfunction. Sci Rep. 2017;7:42885 pubmed 出版商 |
| Thakur A, Mackin S, Irwin R, O Neill K, Pollin G, Walsh C. Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2. Epigenetics Chromatin. 2016;9:53 pubmed |
| Hoang T, Horowitz E, Chaffee B, Qi P, Flake R, Bruney D, et al. Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity. Epigenetics. 2017;12:27-40 pubmed 出版商 |
| Daniel F, Alves S, Vieira D, Biz M, Daniel I, Modolo F. Immunohistochemical expression of DNA methyltransferases 1, 3a, and 3b in actinic cheilitis and lip squamous cell carcinomas. J Oral Pathol Med. 2016;45:774-779 pubmed 出版商 |
| Xu X, Tan X, Hulshoff M, Wilhelmi T, Zeisberg M, Zeisberg E. Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells. FEBS Lett. 2016;590:1222-33 pubmed 出版商 |
| Hong B, Su Z, Zhang C, Yang Y, Guo Y, Li W, et al. Reserpine Inhibit the JB6 P+ Cell Transformation Through Epigenetic Reactivation of Nrf2-Mediated Anti-oxidative Stress Pathway. AAPS J. 2016;18:659-69 pubmed 出版商 |
| Dhawan S, Dirice E, Kulkarni R, Bhushan A. Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication. Diabetes. 2016;65:1208-18 pubmed 出版商 |
| Amouroux R, Nashun B, Shirane K, Nakagawa S, Hill P, D Souza Z, et al. De novo DNA methylation drives 5hmC accumulation in mouse zygotes. Nat Cell Biol. 2016;18:225-233 pubmed 出版商 |
| Li Y, Seah M, O NEILL C. Mapping global changes in nuclear cytosine base modifications in the early mouse embryo. Reproduction. 2016;151:83-95 pubmed 出版商 |
| Kita H, Okamoto K, Kushima R, Kawauchi A, Chano T. Dimethyl sulfoxide induces chemotherapeutic resistance in the treatment of testicular embryonal carcinomas. Oncol Lett. 2015;10:661-666 pubmed |
| Tsukada Y, Akiyama T, Nakayama K. Maternal TET3 is dispensable for embryonic development but is required for neonatal growth. Sci Rep. 2015;5:15876 pubmed 出版商 |
| Dhawan S, Tschen S, Zeng C, Guo T, Hebrok M, MATVEYENKO A, et al. DNA methylation directs functional maturation of pancreatic β cells. J Clin Invest. 2015;125:2851-60 pubmed 出版商 |
| Emperle M, Rajavelu A, Reinhardt R, Jurkowska R, Jeltsch A. Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase. J Biol Chem. 2014;289:29602-13 pubmed 出版商 |
| Chuang C, Wang W, Li C, Ko C, Chou Y, Chuu C, et al. The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer. Cell Death Dis. 2014;5:e1220 pubmed 出版商 |
| Takahashi M, Kamei Y, Ehara T, Yuan X, Suganami T, Takai Igarashi T, et al. Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes. Biochem Biophys Res Commun. 2013;434:873-8 pubmed 出版商 |
| Park E, Park Y, Shin C, Park S, Ahn S, Kim D, et al. Hepatitis B virus inhibits liver regeneration via epigenetic regulation of urokinase-type plasminogen activator. Hepatology. 2013;58:762-76 pubmed 出版商 |
| Leitch H, McEwen K, Turp A, Encheva V, Carroll T, Grabole N, et al. Naive pluripotency is associated with global DNA hypomethylation. Nat Struct Mol Biol. 2013;20:311-6 pubmed 出版商 |
| Sheikh M, Malik Y, Yu H, Lai M, Wang X, Zhu X. Epigenetic regulation of Dpp6 expression by Dnmt3b and its novel role in the inhibition of RA induced neuronal differentiation of P19 cells. PLoS ONE. 2013;8:e55826 pubmed 出版商 |
| Zimmermann N, Zschocke J, Perisic T, Yu S, Holsboer F, Rein T. Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels. Biochem J. 2012;448:93-102 pubmed 出版商 |
| Hong G, Bain L. Sodium arsenite represses the expression of myogenin in C2C12 mouse myoblast cells through histone modifications and altered expression of Ezh2, Glp, and Igf-1. Toxicol Appl Pharmacol. 2012;260:250-9 pubmed 出版商 |
| Stadtfeld M, Apostolou E, Ferrari F, Choi J, Walsh R, Chen T, et al. Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nat Genet. 2012;44:398-405, S1-2 pubmed 出版商 |
| Selvakumar T, Gjidoda A, Hovde S, Henry R. Regulation of human RNA polymerase III transcription by DNMT1 and DNMT3a DNA methyltransferases. J Biol Chem. 2012;287:7039-50 pubmed 出版商 |
| KurdÃková V, Smolinský R, GvoždÃk L. Mothers matter too: benefits of temperature oviposition preferences in newts. PLoS ONE. 2011;6:e23842 pubmed 出版商 |
| Pawlak M, Jaenisch R. De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. Genes Dev. 2011;25:1035-40 pubmed 出版商 |
| Nasonkin I, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A. Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011;519:1914-30 pubmed 出版商 |
| Daniel F, Rivero E, Modolo F, Lopes T, Salum F. Immunohistochemical expression of DNA methyltransferases 1, 3a and 3b in oral leukoplakias and squamous cell carcinomas. Arch Oral Biol. 2010;55:1024-30 pubmed 出版商 |
| Kashiwagi K, Nimura K, Ura K, Kaneda Y. DNA methyltransferase 3b preferentially associates with condensed chromatin. Nucleic Acids Res. 2011;39:874-88 pubmed 出版商 |
| Pierard V, Guiguen A, Colin L, Wijmeersch G, Vanhulle C, Van Driessche B, et al. DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcri. J Biol Chem. 2010;285:19434-49 pubmed 出版商 |
| Wu Y, Alvarez M, Slamon D, Koeffler P, Vadgama J. Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. BMC Cancer. 2010;10:32 pubmed 出版商 |
| Fan H, Liu D, Qiu X, Qiao F, Wu Q, Su X, et al. A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma. BMC Med. 2010;8:12 pubmed 出版商 |
| Meilinger D, Fellinger K, Bultmann S, Rothbauer U, Bonapace I, Klinkert W, et al. Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells. EMBO Rep. 2009;10:1259-64 pubmed 出版商 |
| Ko C, Hsu H, Shen M, Chang W, Wang J. Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex. J Biol Chem. 2008;283:30919-32 pubmed 出版商 |
| Zhu F, Xia X, Liu B, Shen J, Hu Y, Person M, et al. IKKalpha shields 14-3-3sigma, a G(2)/M cell cycle checkpoint gene, from hypermethylation, preventing its silencing. Mol Cell. 2007;27:214-27 pubmed |
| Oh B, Kim H, Park H, Shim Y, Choi J, Park C, et al. DNA methyltransferase expression and DNA methylation in human hepatocellular carcinoma and their clinicopathological correlation. Int J Mol Med. 2007;20:65-73 pubmed |
| Tadokoro Y, Ema H, Okano M, Li E, Nakauchi H. De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells. J Exp Med. 2007;204:715-22 pubmed |
| Park I, Sohn B, Yu E, Suh D, Chung Y, Lee J, et al. Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Gastroenterology. 2007;132:1476-94 pubmed |
| Spada F, Haemmer A, Kuch D, Rothbauer U, Schermelleh L, Kremmer E, et al. DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells. J Cell Biol. 2007;176:565-71 pubmed |
| Nimura K, Ishida C, Koriyama H, Hata K, Yamanaka S, Li E, et al. Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation. Genes Cells. 2006;11:1225-37 pubmed |
| Shen Y, Chow J, Wang Z, Fan G. Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells. Hum Mol Genet. 2006;15:2623-35 pubmed |
| Iwatani M, Ikegami K, Kremenska Y, Hattori N, Tanaka S, Yagi S, et al. Dimethyl sulfoxide has an impact on epigenetic profile in mouse embryoid body. Stem Cells. 2006;24:2549-56 pubmed |
| Tsumura A, Hayakawa T, Kumaki Y, Takebayashi S, Sakaue M, Matsuoka C, et al. Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells. 2006;11:805-14 pubmed |
| Jones B, Chen J. Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development. EMBO J. 2006;25:2443-52 pubmed |
| Ueda Y, Okano M, Williams C, Chen T, Georgopoulos K, Li E. Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome. Development. 2006;133:1183-92 pubmed |
| Galetzka D, Tralau T, Stein R, Haaf T. Expression of DNMT3A transcripts and nucleolar localization of DNMT3A protein in human testicular and fibroblast cells suggest a role for de novo DNA methylation in nucleolar inactivation. J Cell Biochem. 2006;98:885-94 pubmed |
| MacDonald J, Gin C, Roskams A. Stage-specific induction of DNA methyltransferases in olfactory receptor neuron development. Dev Biol. 2005;288:461-73 pubmed |
| Qiu Y, Mirkin B, Dwivedi R. Inhibition of DNA methyltransferase reverses cisplatin induced drug resistance in murine neuroblastoma cells. Cancer Detect Prev. 2005;29:456-63 pubmed |
| Park H, Yu E, Shim Y. DNA methyltransferase expression and DNA hypermethylation in human hepatocellular carcinoma. Cancer Lett. 2006;233:271-8 pubmed |
| Oka M, Meacham A, Hamazaki T, Rodic N, Chang L, Terada N. De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine. Oncogene. 2005;24:3091-9 pubmed |
| Stempak J, Sohn K, Chiang E, Shane B, Kim Y. Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model. Carcinogenesis. 2005;26:981-90 pubmed |
| Feng J, Chang H, Li E, Fan G. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J Neurosci Res. 2005;79:734-46 pubmed |
| Leu Y, Yan P, Fan M, Jin V, Liu J, Curran E, et al. Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Res. 2004;64:8184-92 pubmed |
| Park I, Sohn B, Choo J, Joe C, Seong J, Lee Y, et al. Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development. J Cell Biochem. 2005;94:585-96 pubmed |
| Weisenberger D, Velicescu M, Cheng J, Gonzales F, Liang G, Jones P. Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation. Mol Cancer Res. 2004;2:62-72 pubmed |
| Yan Q, Cho E, Lockett S, Muegge K. Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin. Mol Cell Biol. 2003;23:8416-28 pubmed |
| Choi M, Shim Y, Hwa J, Lee S, Ro J, Kim J, et al. Expression of DNA methyltransferases in multistep hepatocarcinogenesis. Hum Pathol. 2003;34:11-7 pubmed |
| Chen T, Ueda Y, Xie S, Li E. A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation. J Biol Chem. 2002;277:38746-54 pubmed |
| Dennis K, Fan T, Geiman T, Yan Q, Muegge K. Lsh, a member of the SNF2 family, is required for genome-wide methylation. Genes Dev. 2001;15:2940-4 pubmed |
