产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
LANA2 Antibody (CM-A807) - BSA Free
目录 :
NB200-167
规格 :
0.1 ml (also 0.025 ml)
价格 :
379美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CM-A807
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 13
参考文献
Choi U, Lee J, Park A, Jung K, Lee S, Choi Y, et al. Herpesvirus-induced spermidine synthesis and eIF5A hypusination for viral episomal maintenance. Cell Rep. 2022;40:111234 pubmed 出版商
Moodad S, El Hajj R, Hleihel R, Hajjar L, Tawil N, Karam M, et al. Lenalidomide in Combination with Arsenic Trioxide: an Effective Therapy for Primary Effusion Lymphoma. Cancers (Basel). 2020;12: pubmed 出版商
Golas G, Jang S, Naik N, Alonso J, Papp B, Toth Z. Comparative analysis of the viral interferon regulatory factors of KSHV for their requisite for virus production and inhibition of the type I interferon pathway. Virology. 2020;541:160-173 pubmed 出版商
Chen J, Dai L, Goldstein A, Zhang H, Tang W, Forrest J, et al. Identification of new antiviral agents against Kaposi's sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation. PLoS Pathog. 2019;15:e1008156 pubmed 出版商
Xiang Q, Ju H, Li Q, Mei S, Chen D, Choi Y, et al. Human Herpesvirus 8 Interferon Regulatory Factors 1 and 3 Mediate Replication and Latency Activities via Interactions with USP7 Deubiquitinase. J Virol. 2018;92: pubmed 出版商
Lee H, Li F, Choi U, Yu H, Aldrovandi G, Feng P, et al. Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. MBio. 2018;9: pubmed 出版商
Liang Q, Chang B, Lee P, Brulois K, Ge J, Shi M, et al. Identification of the Essential Role of Viral Bcl-2 for Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication. J Virol. 2015;89:5308-17 pubmed 出版商
Zuo J, Hislop A, Leung C, Sabbah S, Rowe M. Kaposi's sarcoma-associated herpesvirus-encoded viral IRF3 modulates major histocompatibility complex class II (MHC-II) antigen presentation through MHC-II transactivator-dependent and -independent mechanisms: implications for oncogenesis. J Virol. 2013;87:5340-50 pubmed 出版商
Marcos Villar L, Gallego P, Munoz Fontela C, de la Cruz Herrera C, Campagna M, Gonzalez D, et al. Kaposi's sarcoma-associated herpesvirus lana2 protein interacts with the pocket proteins and inhibits their sumoylation. Oncogene. 2014;33:495-503 pubmed 出版商
Marcos Villar L, Campagna M, Lopitz Otsoa F, Gallego P, González Santamaría J, Gonzalez D, et al. Covalent modification by SUMO is required for efficient disruption of PML oncogenic domains by Kaposi's sarcoma-associated herpesvirus latent protein LANA2. J Gen Virol. 2011;92:188-94 pubmed 出版商
Sarek G, Järviluoma A, Moore H, Tojkander S, Vartia S, Biberfeld P, et al. Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV latency. PLoS Pathog. 2010;6:e1000818 pubmed 出版商
Marcos Villar L, Lopitz Otsoa F, Gallego P, Munoz Fontela C, González Santamaría J, Campagna M, et al. Kaposi's sarcoma-associated herpesvirus protein LANA2 disrupts PML oncogenic domains and inhibits PML-mediated transcriptional repression of the survivin gene. J Virol. 2009;83:8849-58 pubmed 出版商
Shin Y, Joo C, Gack M, Lee H, Jung J. Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expression. Cancer Res. 2008;68:1751-9 pubmed 出版商
图像
图像 1 :
Novus Biologicals NB200-167 图像 1
Western Blot: LANA2 Antibody (CM-A807) [NB200-167] - Detection of LANA2 in infected lysates (30 ug) using 2 ug/ml of NB 200-167. ECL detection 1.5 minutes. Lane 1: BCBL-1 (KSHV+) Lane 2: BC-1 (KSHV+/EBV+) Lane 3: BCP-1 (KSHV+)
产品信息
品牌 :
Novus
master code :
NB200-167
SKU号 :
NB200-167
产品名称 :
LANA2 Antibody (CM-A807) - BSA Free
描述 :
The LANA2 Antibody (CM-A807) - BSA Free from Novus is a mouse monoclonal antibody to LANA2. This antibody reacts with human, mouse, virus. The LANA2 Antibody (CM-A807) - BSA Free has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockout Validated.
靶标 :
LANA2
类别 :
一抗
sizes available :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
CM-A807
浓度 :
2.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
重组LANA2融合蛋白
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 病毒
特异性 :
This is specific for KSHV LANA2 (residues 143-310 epitope recognition)
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/LANA2-Antibody-(CM-A807)-Western-Blot-NB200-167-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/LANA2-Antibody-(CM-A807)-Western-Blot-NB200-167-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/LANA2-Antibody-(CM-A807)-Immunohistochemistry-Paraffin-NB200-167-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/LANA2-Antibody-(CM-A807)-Immunohistochemistry-Paraffin-NB200-167-img0004.jpg
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡, 免疫组化冷冻, 基因敲除验证
美元 :
379美元
别名 :
LANA 2, LANA-2, Latency-associated nuclear antigen 2, vIRF 3, vIRF3, vIRF-3
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。