产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
ER乙/NR3A2抗体(6A12)
目录 :
NB200-303
规格 :
100微升
价格 :
449美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6A12
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 15
参考文献
Asavasupreechar T, Chan M, Saito R, Miki Y, Boonyaratanakornkit V, Sasano H. Sex steroid metabolism and actions in non-small cell lung carcinoma. J Steroid Biochem Mol Biol. 2019;193:105440 pubmed 出版商
Andersson S, Sundberg M, Pristovšek N, Ibrahim A, Jonsson P, Katona B, et al. Insufficient antibody validation challenges oestrogen receptor beta research. Nat Commun. 2017;8:15840 pubmed 出版商
Vivar O, Zhao X, Saunier E, Griffin C, Mayba O, Tagliaferri M, et al. Estrogen receptor beta binds to and regulates three distinct classes of target genes. J Biol Chem. 2010;285:22059-66 pubmed 出版商
Vivar O, Saunier E, Leitman D, Firestone G, Bjeldanes L. Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethane. Endocrinology. 2010;151:1662-7 pubmed 出版商
Ivanova M, Mazhawidza W, Dougherty S, Minna J, Klinge C. Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells. Mol Cell Endocrinol. 2009;305:12-21 pubmed 出版商
Klinge C, Wickramasinghe N, Ivanova M, Dougherty S. Resveratrol stimulates nitric oxide production by increasing estrogen receptor alpha-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells. FASEB J. 2008;22:2185-97 pubmed 出版商
Cvoro A, Paruthiyil S, Jones J, Tzagarakis Foster C, Clegg N, Tatomer D, et al. Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract. Endocrinology. 2007;148:538-47 pubmed
Cvoro A, Tzagarakis Foster C, Tatomer D, Paruthiyil S, Fox M, Leitman D. Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression. Mol Cell. 2006;21:555-64 pubmed
Hopp T, Weiss H, Parra I, Cui Y, Osborne C, Fuqua S. Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer. Clin Cancer Res. 2004;10:7490-9 pubmed
Tee M, Rogatsky I, Tzagarakis Foster C, Cvoro A, An J, Christy R, et al. Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Mol Biol Cell. 2004;15:1262-72 pubmed
Speirs V. Correspondence re: S. A. W. Fuqua et al., Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters. Cancer Res.,63: 2434-2439, 2003. Cancer Res. 2003;63:9055 pubmed
Konstantinopoulos P, Kominea A, Vandoros G, Sykiotis G, Andricopoulos P, Varakis I, et al. Oestrogen receptor beta (ERbeta) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation. Eur J Cancer. 2003;39:1251-8 pubmed
Bianco N, Perry G, Smith M, Templeton D, Montano M. Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Mol Endocrinol. 2003;17:1344-55 pubmed
Saji S, Omoto Y, Shimizu C, Warner M, Hayashi Y, Horiguchi S, et al. Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor. Cancer Res. 2002;62:4849-53 pubmed
Speirs V, Skliris G, Burdall S, Carder P. Distinct expression patterns of ER alpha and ER beta in normal human mammary gland. J Clin Pathol. 2002;55:371-4 pubmed
图像
图像 1 :
Novus Biologicals NB200-303 图像 1
Western Blot: ER beta/NR3A2 Antibody (6A12) [NB200-303] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Estrogen Receptor beta antibody [6A12]. The HRP-conjugated anti-mouse IgG antibody was used to detect the primary antibody.
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB200-303
SKU号 :
NB200-303
产品名称 :
ER乙/NR3A2抗体(6A12)
描述 :
The ER beta/NR3A2 Antibody (6A12) from Novus is a mouse monoclonal antibody to ER beta/NR3A2. This antibody reacts with human. The ER beta/NR3A2 Antibody (6A12) has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Chromatin Immunoprecipitation (ChIP).
靶标 :
ER乙/NR3A2
类别 :
一抗
单位尺寸 :
100微升
缓冲液 :
PBS(pH值7.4)
克隆性 :
单克隆
克隆 :
6A12
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
氨基酸1-153人的ER在大肠杆菌中表达
抗体亚型 :
IgG2a
纯度 :
蛋白质G纯化
物种 :
人类
特异性 :
This is specific for Estrogen receptor-Beta
理论上的分子量 :
55 kDa
基因符号 :
ESR2
应用 :
免疫印迹, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 染色质免疫沉淀 (ChIP)
美元 :
449美元
别名 :
Erb, ER-beta, ESR-BETA, ESTRB, estrogen receptor 2 (ER beta), estrogen receptor beta, estrogen receptor beta 4, NR3A2ESRB, Nuclear receptor subfamily 3 group A member 2
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。