产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
ER乙/NR3A2抗体(14C8)
目录 :
NB200-305
规格 :
100微升
价格 :
429美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
14C8
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀
, 免疫组化-石蜡切片, 免疫组化-冰冻切片, dot blot
更多信息或购买 :
文章摘录数: 75
参考文献 |
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Sato R, Suzuki T, Katayose Y, Miura K, Shiiba K, Miki Y, et al. Aromatase in colon carcinoma. Anticancer Res. 2012;32:3069-75 pubmed
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Dohi O, Hatori M, Suzuki T, Ono K, Hosaka M, Akahira J, et al. Sex steroid receptors expression and hormone-induced cell proliferation in human osteosarcoma. Cancer Sci. 2008;99:518-23 pubmed
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Bukulmez O, Hardy D, Carr B, Word R, Mendelson C. Inflammatory status influences aromatase and steroid receptor expression in endometriosis. Endocrinology. 2008;149:1190-204 pubmed
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Caiazza F, Galluzzo P, Lorenzetti S, Marino M. 17Beta-estradiol induces ERbeta up-regulation via p38/MAPK activation in colon cancer cells. Biochem Biophys Res Commun. 2007;359:102-7 pubmed
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Gruvberger Saal S, Bendahl P, Saal L, Laakso M, Hegardt C, Edén P, et al. Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma. Clin Cancer Res. 2007;13:1987-94 pubmed
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Galluzzo P, Caiazza F, Moreno S, Marino M. Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation. Endocr Relat Cancer. 2007;14:153-67 pubmed
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Cvoro A, Paruthiyil S, Jones J, Tzagarakis Foster C, Clegg N, Tatomer D, et al. Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract. Endocrinology. 2007;148:538-47 pubmed
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Al Dhaheri M, Rowan B. Protein kinase A exhibits selective modulation of estradiol-dependent transcription in breast cancer cells that is associated with decreased ligand binding, altered estrogen receptor alpha promoter interaction, and changes in receptor phosphorylation. Mol Endocrinol. 2007;21:439-56 pubmed
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Skliris G, Lewis A, Emberley E, Peng B, Weebadda W, Kemp A, et al. Estrogen receptor-beta regulates psoriasin (S100A7) in human breast cancer. Breast Cancer Res Treat. 2007;104:75-85 pubmed
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Dietrich W, Haitel A, Holzer G, Huber J, Kolbus A, Tschugguel W. Estrogen receptor-beta is the predominant estrogen receptor subtype in normal human synovia. J Soc Gynecol Investig. 2006;13:512-7 pubmed
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Skliris G, Leygue E, Curtis Snell L, Watson P, Murphy L. Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours. Br J Cancer. 2006;95:616-26 pubmed
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Savinov A, Remacle A, Golubkov V, Krajewska M, Kennedy S, Duffy M, et al. Matrix metalloproteinase 26 proteolysis of the NH2-terminal domain of the estrogen receptor beta correlates with the survival of breast cancer patients. Cancer Res. 2006;66:2716-24 pubmed
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Cvoro A, Tzagarakis Foster C, Tatomer D, Paruthiyil S, Fox M, Leitman D. Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression. Mol Cell. 2006;21:555-64 pubmed
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Poola I, Fuqua S, De Witty R, Abraham J, Marshallack J, Liu A. Estrogen receptor alpha-negative breast cancer tissues express significant levels of estrogen-independent transcription factors, ERbeta1 and ERbeta5: potential molecular targets for chemoprevention. Clin Cancer Res. 2005;11:7579-85 pubmed
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Schwartz A, Prysak G, Murphy V, Lonardo F, Pass H, Schwartz J, et al. Nuclear estrogen receptor beta in lung cancer: expression and survival differences by sex. Clin Cancer Res. 2005;11:7280-7 pubmed
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Poola I, Abraham J, Baldwin K, Saunders A, Bhatnagar R. Estrogen receptors beta4 and beta5 are full length functionally distinct ERbeta isoforms: cloning from human ovary and functional characterization. Endocrine. 2005;27:227-38 pubmed
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Zheng F, Wu R, Smith C, O Malley B. Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. Mol Cell Biol. 2005;25:8273-84 pubmed
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Ishibashi H, Suzuki T, Suzuki S, Niikawa H, Lu L, Miki Y, et al. Progesterone receptor in non-small cell lung cancer--a potent prognostic factor and possible target for endocrine therapy. Cancer Res. 2005;65:6450-8 pubmed
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Helguero L, Faulds M, Gustafsson J, Haldosén L. Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11. Oncogene. 2005;24:6605-16 pubmed
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Miki Y, Suzuki T, Tazawa C, Ishizuka M, Semba S, Gorai I, et al. Analysis of gene expression induced by diethylstilbestrol (DES) in human primitive Mullerian duct cells using microarray. Cancer Lett. 2005;220:197-210 pubmed
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Hopp T, Weiss H, Parra I, Cui Y, Osborne C, Fuqua S. Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer. Clin Cancer Res. 2004;10:7490-9 pubmed
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Balfe P, McCann A, McGoldrick A, McAllister K, Kennedy M, Dervan P, et al. Estrogen receptor alpha and beta profiling in human breast cancer. Eur J Surg Oncol. 2004;30:469-74 pubmed
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Speirs V, Carder P, Lane S, Dodwell D, Lansdown M, Hanby A. Oestrogen receptor beta: what it means for patients with breast cancer. Lancet Oncol. 2004;5:174-81 pubmed
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Tee M, Rogatsky I, Tzagarakis Foster C, Cvoro A, An J, Christy R, et al. Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Mol Biol Cell. 2004;15:1262-72 pubmed
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Skliris G, Munot K, Bell S, Carder P, Lane S, Horgan K, et al. Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model. J Pathol. 2003;201:213-20 pubmed
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Li X, Hisaoka M, Hashimoto H. Expression of estrogen receptors alpha and beta in soft tissue sarcomas: Immunohistochemical and molecular analysis. Pathol Int. 2003;53:671-9 pubmed
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Omoto Y, Eguchi H, Yamamoto Yamaguchi Y, Hayashi S. Estrogen receptor (ER) beta1 and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7. Oncogene. 2003;22:5011-20 pubmed
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Fuqua S, Schiff R, Parra I, Moore J, Mohsin S, Osborne C, et al. Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters. Cancer Res. 2003;63:2434-9 pubmed
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Linja M, Savinainen K, Tammela T, Isola J, Visakorpi T. Expression of ERalpha and ERbeta in prostate cancer. Prostate. 2003;55:180-6 pubmed
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Speirs V, Skliris G, Burdall S, Carder P. Distinct expression patterns of ER alpha and ER beta in normal human mammary gland. J Clin Pathol. 2002;55:371-4 pubmed
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Skliris G, Carder P, Lansdown M, Speirs V. Immunohistochemical detection of ERbeta in breast cancer: towards more detailed receptor profiling?. Br J Cancer. 2001;84:1095-8 pubmed
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图像
图像 1 :
Western Blot: ER beta/NR3A2 Antibody (14C8) [NB200-305] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Estrogen Receptor beta antibody [14C8] diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (NBP2-19382) was used to detect the primary antibody
产品信息
品牌 :
Novus
master code :
NB200-305
SKU号 :
NB200-305
产品名称 :
ER乙/NR3A2抗体(14C8)
描述 :
The ER beta/NR3A2 Antibody (14C8) from Novus is a mouse monoclonal antibody to ER beta/NR3A2. This antibody reacts with human, mouse, monkey, rabbit. The ER beta/NR3A2 Antibody (14C8) has been validated for the following applications: Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Dot Blot.
靶标 :
ER乙/NR3A2
类别 :
一抗
sizes available :
100微升
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
14C8
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
氨基酸1-153人的ER乙在大肠杆菌中表达
抗体亚型 :
IgG2b
纯度 :
蛋白质G纯化
物种 :
Human, Mouse, Monkey, Rabbit
特异性 :
Strong Erb staining in epithelial cell nuclei
理论上的分子量 :
59 kDa
基因符号 :
ESR2
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ER-beta-NR3A2-Antibody-(14C8)-Western-Blot-NB200-305-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ER-beta-NR3A2-Antibody-(14C8)-Immunohistochemistry-Paraffin-NB200-305-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Estrogen-Receptor-beta-Antibody-(14C8)-Immunohistochemistry-Paraffin-NB200-305-img0003.jpg
accessionNumbers :
Q92731
应用 :
Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Dot Blot
美元 :
429美元
别名 :
Erb, ER-beta, ESR-BETA, ESTRB, estrogen receptor 2 (ER beta), estrogen receptor beta, estrogen receptor beta 4, NR3A2ESRB, Nuclear receptor subfamily 3 group A member 2
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。