产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
CUGBP1/CELF1抗体(3B1)
目录 :
NB200-316
规格 :
0.1 ml (also 0.025 ml)
价格 :
429美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3B1
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, EMSA, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 12
参考文献
Markmiller S, Sathe S, Server K, Nguyen T, Fulzele A, Cody N, et al. Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress. Cell Rep. 2021;36:109685 pubmed 出版商
de Haro M, Al Ramahi I, Jones K, Holth J, Timchenko L, Botas J. Smaug/SAMD4A restores translational activity of CUGBP1 and suppresses CUG-induced myopathy. PLoS Genet. 2013;9:e1003445 pubmed 出版商
Xiao Q, Ford A, Xu J, Yan P, Lee K, Gonzales E, et al. Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia. J Neurosci. 2012;32:13587-96 pubmed
Ward A, Rimer M, Killian J, Dowling J, Cooper T. CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1. Hum Mol Genet. 2010;19:3614-22 pubmed 出版商
Hashem V, Galloway J, Mori M, Willemsen R, Oostra B, Paylor R, et al. Ectopic expression of CGG containing mRNA is neurotoxic in mammals. Hum Mol Genet. 2009;18:2443-51 pubmed 出版商
Orengo J, Chambon P, Metzger D, Mosier D, Snipes G, Cooper T. Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy. Proc Natl Acad Sci U S A. 2008;105:2646-51 pubmed 出版商
Kress C, Gautier Courteille C, Osborne H, Babinet C, Paillard L. Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice. Mol Cell Biol. 2007;27:1146-57 pubmed
Lin X, Miller J, Mankodi A, Kanadia R, Yuan Y, Moxley R, et al. Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy. Hum Mol Genet. 2006;15:2087-97 pubmed
Mankodi A, Lin X, Blaxall B, Swanson M, Thornton C. Nuclear RNA foci in the heart in myotonic dystrophy. Circ Res. 2005;97:1152-5 pubmed
Mankodi A, Teng Umnuay P, Krym M, Henderson D, Swanson M, Thornton C. Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2. Ann Neurol. 2003;54:760-8 pubmed
Savkur R, Philips A, Cooper T. Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy. Nat Genet. 2001;29:40-7 pubmed
Good P, Chen Q, Warner S, Herring D. A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator. J Biol Chem. 2000;275:28583-92 pubmed
图像
图像 1 :
Novus Biologicals NB200-316 图像 1
Western Blot: CUGBP1 Antibody (3B1) [NB200-316] - Detection of CUG-BP1 in several cell lysates.
产品信息
品牌 :
Novus
master code :
NB200-316
SKU号 :
NB200-316
产品名称 :
CUGBP1/CELF1抗体(3B1)
描述 :
The CUGBP1/CELF1 Antibody (3B1) from Novus is a mouse monoclonal antibody to CUGBP1/CELF1. This antibody reacts with human, mouse, rat, porcine, bovine, primate, rabbit. The CUGBP1/CELF1 Antibody (3B1) has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Gel Super Shift Assays.
靶标 :
CUGBP1/CELF1
类别 :
一抗
sizes available :
0.1 ml (also 0.025 ml)
缓冲液 :
三羟甲基氨基甲烷甘氨酸和0.15M氯化钠
克隆性 :
单克隆
克隆 :
3B1
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Full-length human CUGBP1 [UniProt# Q92879]
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠, 猪, 牛, 灵长类动物, 兔
理论上的分子量 :
50 kDa
基因符号 :
CELF1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-Antibody-(3B1)-Western-Blot-NB200-316-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-Antibody-(3B1)-Western-Blot-NB200-316-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-Antibody-(3B1)-Immunocytochemistry-Immunofluorescence-NB200-316-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-Antibody-(3B1)-Immunocytochemistry-Immunofluorescence-NB200-316-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-CELF1-Antibody-(3B1)-Immunohistochemistry-Paraffin-NB200-316-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-CELF1-Antibody-(3B1)-Immunohistochemistry-Paraffin-NB200-316-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-Antibody-(3B1)-Flow-Cytometry-NB200-316-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-Antibody-(3B1)-Flow-Cytometry-NB200-316-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-Antibody-(3B1)-Simple-Western-NB200-316-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CUGBP1-Antibody-(3B1)-Simple-Western-NB200-316-img0009.jpg
accessionNumbers :
Q92879
应用 :
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Gel Super Shift Assays
美元 :
429美元
别名 :
BRUNOL250 kDa nuclear polyadenylated RNA-binding protein, bruno-like 2, Bruno-like protein 2, CUG RNA-binding protein, CUG triplet repeat, RNA binding protein 1, CUG triplet repeat, RNA-binding protein 1, CUG-BP, CUG-BP- and ETR-3-like factor 1, CUGBP Elav-like family member 1, CUGBP, Elav-like family member 1, CUGBP1CUG triplet repeat RNA-binding protein 1, CUGBPCELF-1, Deadenylation factor CUG-BP, EDEN-BP, EDEN-BP homolog, embryo deadenylation element binding protein, Embryo deadenylation element-binding protein homolog, hNab50, NAB50CUG-BP1, NAPOR, nuclear polyadenylated RNA-binding protein, 50-kD, RNA-binding protein BRUNOL-2
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。