产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
xCT Antibody - BSA Free
目录 :
NB300-317
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
14D5
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 20
参考文献
Wang J, Wang Y, Liu Y, Cai X, Huang X, Fu W, et al. Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model. Cell Death Discov. 2022;8:127 pubmed 出版商
Zhang H, Hughes C, Li W, He J, Surdez D, El Naggar A, et al. Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma. Cancer Discov. 2021;11:2884-2903 pubmed 出版商
Klinger S. Segment-specific effects of resveratrol on porcine small intestinal dipeptide absorption depend on the mucosal pH and are due to different mechanisms: potential roles of different transport proteins and protein kinases. J Nutr Biochem. 2020;85:108467 pubmed 出版商
Long Y, Tao H, Karachi A, Grippin A, Jin L, Chang Y, et al. Dysregulation of Glutamate Transport Enhances Treg Function That Promotes VEGF Blockade Resistance in Glioblastoma. Cancer Res. 2020;80:499-509 pubmed 出版商
Koizumi M, Ueda K, Niimura F, Nishiyama A, Yanagita M, Saito A, et al. Podocyte Injury Augments Intrarenal Angiotensin II Generation and Sodium Retention in a Megalin-Dependent Manner. Hypertension. 2019;74:509-517 pubmed 出版商
Hayasaki T, Ishimoto T, Doke T, Hirayama A, Soga T, Furuhashi K, et al. Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase. J Nutr Biochem. 2019;71:54-62 pubmed 出版商
Huang M, Lin Y, Chang C, Lei F, Ho E, Liu R, et al. RGS4 deficit in prefrontal cortex contributes to the behaviors related to schizophrenia via system xc--mediated glutamatergic dysfunction in mice. Theranostics. 2018;8:4781-4794 pubmed 出版商
Masuda T, Watanabe Y, Fukuda K, Watanabe M, Onishi A, Ohara K, et al. Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat. Am J Physiol Renal Physiol. 2018;315:F653-F664 pubmed 出版商
Klinger S, Breves G. Resveratrol Inhibits Porcine Intestinal Glucose and Alanine Transport: Potential Roles of Na?/K?-ATPase Activity, Protein Kinase A, AMP-Activated Protein Kinase and the Association of Selected Nutrient Transport Proteins with Detergent Resistant Memb. Nutrients. 2018;10: pubmed 出版商
Fenton R, Poulsen S, de la Mora Chavez S, Soleimani M, Dominguez Rieg J, Rieg T. Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis. Kidney Int. 2017;92:397-414 pubmed 出版商
Chew S, Okazaki Y, Akatsuka S, Wang S, Jiang L, Ohara Y, et al. Rheostatic CD44 isoform expression and its association with oxidative stress in human malignant mesothelioma. Free Radic Biol Med. 2017;106:91-99 pubmed 出版商
Linher Melville K, Haftchenary S, Gunning P, Singh G. Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells. Mol Cell Biochem. 2015;405:205-21 pubmed 出版商
Ozkucur N, Song B, Bola S, Zhang L, Reid B, Fu G, et al. NHE3 phosphorylation via PKC? marks the polarity and orientation of directionally migrating cells. Cell Mol Life Sci. 2014;71:4653-4663 pubmed 出版商
Perike S, Ozkucur N, Sharma P, Staroske W, Bläsche R, Barth K, et al. Phospho-NHE3 forms membrane patches and interacts with beta-actin to sense and maintain constant direction during cell migration. Exp Cell Res. 2014;324:13-29 pubmed 出版商
Liu T, Jose P. Gastrin induces sodium-hydrogen exchanger 3 phosphorylation and mTOR activation via a phosphoinositide 3-kinase-/protein kinase C-dependent but AKT-independent pathway in renal proximal tubule cells derived from a normotensive male human. Endocrinology. 2013;154:865-75 pubmed 出版商
Rieg T, Gerasimova M, Murray F, Masuda T, Tang T, Rose M, et al. Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice. Am J Physiol Renal Physiol. 2012;303:F963-71 pubmed 出版商
Ozkucur N, Perike S, Sharma P, Funk R. Persistent directional cell migration requires ion transport proteins as direction sensors and membrane potential differences in order to maintain directedness. BMC Cell Biol. 2011;12:4 pubmed 出版商
Dynia D, Steinmetz A, Kocinsky H. NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase. Am J Physiol Renal Physiol. 2010;298:F745-53 pubmed 出版商
Kocinsky H, Dynia D, Wang T, Aronson P. NHE3 phosphorylation at serines 552 and 605 does not directly affect NHE3 activity. Am J Physiol Renal Physiol. 2007;293:F212-8 pubmed
Kocinsky H, Girardi A, Biemesderfer D, Nguyen T, Mentone S, Orlowski J, et al. Use of phospho-specific antibodies to determine the phosphorylation of endogenous Na+/H+ exchanger NHE3 at PKA consensus sites. Am J Physiol Renal Physiol. 2005;289:F249-58 pubmed
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB300-317
SKU号 :
NB300-317
产品名称 :
xCT Antibody - BSA Free
描述 :
The xCT Antibody - BSA Free from Novus is a rabbit polyclonal antibody to xCT. This antibody reacts with human, mouse, rat. The xCT Antibody - BSA Free has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting.
靶标 :
xCT
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
兔
免疫原 :
This xCT Antibody was prepared from a synthetic peptide made to a region within the N-terminus of the mouse xCT protein (between residues 1-50). [Uniprot: Q9WTR6]
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠
理论上的分子量 :
55 kDa
基因符号 :
SLC7A11
应用 :
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting
美元 :
399美元
别名 :
Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, CCBR1, cystine/glutamate transporter, SLC7A11, solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11, Solute carrier family 7 member 11, solute carrier family 7, (cationic amino acid transporter, y+ system) member 11, xCT
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。