| 参考文献 |
|---|
Borovsk xe1 I, Vo x159 echovsk xfd I, Kr xe1 lovi x10d ov xe1 J. Alu RNA fold links splicing with signal recognition particle proteins. Nucleic Acids Res. 2023;51:8199-8216 pubmed 出版商 |
Xie X, Fan C, Luo B, Zhang J, Jensen L, Burman J, et al. APR-246 Enhances Colorectal Cancer Sensitivity to Radiotherapy. Mol Cancer Ther. 2023;22:947-961 pubmed 出版商 |
Fukuyama K, Motomura E, Okada M. Opposing effects of clozapine and brexpiprazole on β-aminoisobutyric acid: Pathophysiology of antipsychotics-induced weight gain. Schizophrenia (Heidelb). 2023;9:8 pubmed 出版商 |
Xue L, Schnacke P, Frei M, Koch B, Hiblot J, Wombacher R, et al. Probing coenzyme A homeostasis with semisynthetic biosensors. Nat Chem Biol. 2023;19:346-355 pubmed 出版商 |
Fukuyama K, Okada M. Brivaracetam and Levetiracetam Suppress Astroglial L-Glutamate Release through Hemichannel via Inhibition of Synaptic Vesicle Protein. Int J Mol Sci. 2022;23: pubmed 出版商 |
Pengelly R, Bakhtiar D, Borovsk xe1 I, Kr xe1 lovi x10d ov xe1 J, Vo x159 echovsk xfd I. Exonic splicing code and protein binding sites for calcium. Nucleic Acids Res. 2022;50:5493-5512 pubmed 出版商 |
Fukuyama K, Okada M. High frequency oscillations play important roles in development of epileptogenesis/ictogenesis via activation of astroglial signallings. Biomed Pharmacother. 2022;149:112846 pubmed 出版商 |
Wang J, Wang W, Huang X, Cao J, Hou S, Ni X, et al. m6A-dependent upregulation of TRAF6 by METTL3 is associated with metastatic osteosarcoma. J Bone Oncol. 2022;32:100411 pubmed 出版商 |
Fukuyama K, Okada M. Effects of an Atypical Antipsychotic, Zotepine, on Astroglial L-Glutamate Release through Hemichannels: Exploring the Mechanism of Mood-Stabilising Antipsychotic Actions and Antipsychotic-Induced Convulsion. Pharmaceuticals (Basel). 2021;14: pubmed 出版商 |
Wang L, Proulx M, Kim A, Lelarge V, McCaffrey L. A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation. Sci Rep. 2021;11:22807 pubmed 出版商 |
Fukuyama K, Okada M. Effects of Atypical Antipsychotics, Clozapine, Quetiapine and Brexpiprazole on Astroglial Transmission Associated with Connexin43. Int J Mol Sci. 2021;22: pubmed 出版商 |
Fukuyama K, Nakano T, Shiroyama T, Okada M. Chronic Administrations of Guanfacine on Mesocortical Catecholaminergic and Thalamocortical Glutamatergic Transmissions. Int J Mol Sci. 2021;22: pubmed 出版商 |
Presa M, Bailey R, Davis C, Murphy T, Cook J, Walls R, et al. AAV9-mediated FIG4 delivery prolongs life span in Charcot-Marie-Tooth disease type 4J mouse model. J Clin Invest. 2021;131: pubmed 出版商 |
Okada M, Fukuyama K, Shiroyama T, Ueda Y. Brivaracetam prevents astroglial l-glutamate release associated with hemichannel through modulation of synaptic vesicle protein. Biomed Pharmacother. 2021;138:111462 pubmed 出版商 |
Okada M, Matsumoto R, Yamamoto Y, Fukuyama K. Effects of Subchronic Administrations of Vortioxetine, Lurasidone, and Escitalopram on Thalamocortical Glutamatergic Transmission Associated with Serotonin 5-HT7 Receptor. Int J Mol Sci. 2021;22: pubmed 出版商 |
Fukuyama K, Ueda Y, Okada M. Effects of Carbamazepine, Lacosamide and Zonisamide on Gliotransmitter Release Associated with Activated Astroglial Hemichannels. Pharmaceuticals (Basel). 2020;13: pubmed 出版商 |
Fukuyama K, Fukuzawa M, Okada M. Upregulated and Hyperactivated Thalamic Connexin 43 Plays Important Roles in Pathomechanisms of Cognitive Impairment and Seizure of Autosomal Dominant Sleep-Related Hypermotor Epilepsy with S284L-Mutant α4 Subunit of Nicotinic ACh Receptor. Pharmaceuticals (Basel). 2020;13: pubmed 出版商 |
Fukuyama K, Fukuzawa M, Okubo R, Okada M. Upregulated Connexin 43 Induced by Loss-of-Functional S284L-Mutant α4 Subunit of Nicotinic ACh Receptor Contributes to Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy. Pharmaceuticals (Basel). 2020;13: pubmed 出版商 |
Fukuyama K, Okubo R, Murata M, Shiroyama T, Okada M. Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine. Cells. 2020;9: pubmed 出版商 |
Hu M, Lou Y, Liu S, Mao Y, Le F, Wang L, et al. Altered expression of DNA damage repair genes in the brain tissue of mice conceived by in vitro fertilization. Mol Hum Reprod. 2020;26:141-153 pubmed 出版商 |
Fukuyama K, Fukuzawa M, Shiroyama T, Okada M. Pathogenesis and pathophysiology of autosomal dominant sleep-related hypermotor epilepsy with S284L-mutant α4 subunit of nicotinic ACh receptor. Br J Pharmacol. 2020;177:2143-2162 pubmed 出版商 |
Cho H, Kumari N, Thakur N, Vu H, Kim H, Choi S. Decreased APE-1 by Nitroxoline Enhances Therapeutic Effect in a Temozolomide-resistant Glioblastoma: Correlation with Diffusion Weighted Imaging. Sci Rep. 2019;9:16613 pubmed 出版商 |
Bui T, Rennhack J, Mok S, Ling C, Perez M, Roccamo J, et al. Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer. Cell Rep. 2019;29:589-602.e6 pubmed 出版商 |
Song H, Zeng J, Roychoudhury S, Biswas P, Mohapatra B, Ray S, et al. Targeting Histone Chaperone FACT Complex Overcomes 5-Fluorouracil Resistance in Colon Cancer. Mol Cancer Ther. 2020;19:258-269 pubmed 出版商 |
Sun Y, Feng Y, Zhang G, Xu Y. The endonuclease APE1 processes miR-92b formation, thereby regulating expression of the tumor suppressor LDLR in cervical cancer cells. Ther Adv Med Oncol. 2019;11:1758835919855859 pubmed 出版商 |
Malfatti M, Gerratana L, Dalla E, Isola M, Damante G, Di Loreto C, et al. APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC. J Exp Clin Cancer Res. 2019;38:309 pubmed 出版商 |
Smith H, Hirukawa A, Sanguin Gendreau V, Nandi I, Dufour C, Zuo D, et al. An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis. Nat Commun. 2019;10:2901 pubmed 出版商 |
Lee Y, Joo H, Lee E, Cho H, Choi S, Kim C, et al. ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1. Int J Mol Sci. 2019;20: pubmed 出版商 |
Youngworth I, Delany M. A Premature Stop Codon in RAF1 Is the Priority Candidate Causative Mutation of the Inherited Chicken Wingless-2 Developmental Syndrome. Genes (Basel). 2019;10: pubmed 出版商 |
George J, Bessho M, Bessho T. Inactivation of XPF Sensitizes Cancer Cells to Gemcitabine. J Nucleic Acids. 2019;2019:6357609 pubmed 出版商 |
Zhang Q, Chao T, Patil V, Qin Y, Tiwari S, Chiou J, et al. The long noncoding RNA ROCKI regulates inflammatory gene expression. EMBO J. 2019;38: pubmed 出版商 |
Cho W, Jin X, Pang J, Wang Y, Mivechi N, Moskophidis D. The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways. Mol Cell Biol. 2019;39: pubmed 出版商 |
Frossi B, Antoniali G, Yu K, Akhtar N, Kaplan M, Kelley M, et al. Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination. J Biol Chem. 2019;294:5198-5207 pubmed 出版商 |
Antoniali G, Serra F, Lirussi L, Tanaka M, D Ambrosio C, Zhang S, et al. Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. Nat Commun. 2017;8:797 pubmed 出版商 |
Nath S, Roychoudhury S, Kling M, Song H, Biswas P, Shukla A, et al. The extracellular role of DNA damage repair protein APE1 in regulation of IL-6 expression. Cell Signal. 2017;39:18-31 pubmed 出版商 |
Roychoudhury S, Nath S, Song H, Hegde M, Bellot L, Mantha A, et al. Human Apurinic/Apyrimidinic Endonuclease (APE1) Is Acetylated at DNA Damage Sites in Chromatin, and Acetylation Modulates Its DNA Repair Activity. Mol Cell Biol. 2017;37: pubmed 出版商 |
Szczesny B, Marcatti M, Zatarain J, Druzhyna N, Wiktorowicz J, Nagy P, et al. Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics. Sci Rep. 2016;6:36125 pubmed 出版商 |
Yang C, Sengupta S, Hegde P, Mitra J, Jiang S, Holey B, et al. Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A. Nucleic Acids Res. 2017;45:739-748 pubmed 出版商 |
Sengupta S, Mantha A, Song H, Roychoudhury S, Nath S, Ray S, et al. Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair. Oncotarget. 2016;7:75197-75209 pubmed 出版商 |
Akhter N, Takeda Y, Nara H, Araki A, Ishii N, Asao N, et al. Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 (Ape1/Ref-1) Modulates Antigen Presenting Cell-mediated T Helper Cell Type 1 Responses. J Biol Chem. 2016;291:23672-23680 pubmed |
Kelley M, Wikel J, Guo C, Pollok K, Bailey B, Wireman R, et al. Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy. J Pharmacol Exp Ther. 2016;359:300-309 pubmed |
Nikitaki Z, Nikolov V, Mavragani I, Mladenov E, Mangelis A, Laskaratou D, et al. Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET). Free Radic Res. 2016;50:S64-S78 pubmed |
Rauen T, Frye B, Wang J, Raffetseder U, Alidousty C, En Nia A, et al. Cold shock protein YB-1 is involved in hypoxia-dependent gene transcription. Biochem Biophys Res Commun. 2016;478:982-7 pubmed 出版商 |
Duprey Díaz M, Blagburn J, Blanco R. Optic nerve injury upregulates retinoic acid signaling in the adult frog visual system. J Chem Neuroanat. 2016;77:80-92 pubmed 出版商 |
Lee Y, Lim J, Shin J, Choi S, Joo H, Jeon B. Altered Secretory Activity of APE1/Ref-1 D148E Variants Identified in Human Patients With Bladder Cancer. Int Neurourol J. 2016;20:S30-37 pubmed 出版商 |
Wang H, Cai S, Bailey B, Reza Saadatzadeh M, Ding J, Tonsing Carter E, et al. Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist. J Neurosurg. 2017;126:446-459 pubmed 出版商 |
Moreli J, Santos J, Lorenzon Ojea A, Correa Silva S, Fortunato R, Rocha C, et al. Hyperglycemia Differentially Affects Maternal and Fetal DNA Integrity and DNA Damage Response. Int J Biol Sci. 2016;12:466-77 pubmed 出版商 |
Bhakat K, Sengupta S, Adeniyi V, Roychoudhury S, Nath S, Bellot L, et al. Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation. Oncotarget. 2016;7:22590-604 pubmed 出版商 |
Wu J, Liu J, Ko Y, Wang C, Chung Y, Chu K, et al. Haploinsufficiency of RCBTB1 is associated with Coats disease and familial exudative vitreoretinopathy. Hum Mol Genet. 2016;25:1637-47 pubmed 出版商 |
Ahuja A, Jodkowska K, Teloni F, Bizard A, Zellweger R, Herrador R, et al. A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. Nat Commun. 2016;7:10660 pubmed 出版商 |
Aamann M, Nørregaard R, Kristensen M, Stevnsner T, Frøkiær J. Unilateral ureteral obstruction induces DNA repair by APE1. Am J Physiol Renal Physiol. 2016;310:F763-F776 pubmed 出版商 |
Bonora M, Wieckowsk M, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene. 2015;34:1608 pubmed 出版商 |
Pojo M, Gonçalves C, Xavier Magalhães A, Oliveira A, Gonçalves T, Correia S, et al. A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide. Oncotarget. 2015;6:7657-74 pubmed |
Yang S, Zhang J, Zhang Y, Wan X, Zhang C, Huang X, et al. KDM1A triggers androgen-induced miRNA transcription via H3K4me2 demethylation and DNA oxidation. Prostate. 2015;75:936-46 pubmed 出版商 |
Fang Q, Inanç B, Schamus S, Wang X, Wei L, Brown A, et al. HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β. Nat Commun. 2014;5:5513 pubmed 出版商 |
Woo J, Park H, Sung S, Moon B, Suh H, Lim W. Prognostic value of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in breast cancer. PLoS ONE. 2014;9:e99528 pubmed 出版商 |
Kim H, Koedrith P, Lee S, Kim Y, Seo Y. Base excision DNA repair defect in thioredoxin-1 (Trx1)-deficient cells. Mutat Res. 2013;751-752:1-7 pubmed |
Xie J, Zhang L, Li M, Du J, Zhou L, Yang S, et al. Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1 in the resistance to melphalan in multiple myeloma. BMC Cancer. 2014;14:11 pubmed 出版商 |
Karmahapatra S, Saha T, Adhikari S, Woodrick J, Roy R. Redox regulation of apurinic/apyrimidinic endonuclease 1 activity in Long-Evans Cinnamon rats during spontaneous hepatitis. Mol Cell Biochem. 2014;388:185-93 pubmed 出版商 |
Madlener S, Strobel T, Vose S, Saydam O, Price B, Demple B, et al. Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance. Proc Natl Acad Sci U S A. 2013;110:17844-9 pubmed 出版商 |
Sengupta S, Mitra S, Bhakat K. Dual regulatory roles of human AP-endonuclease (APE1/Ref-1) in CDKN1A/p21 expression. PLoS ONE. 2013;8:e68467 pubmed 出版商 |
Cun Y, Dai N, Xiong C, Li M, Sui J, Qian C, et al. Silencing of APE1 enhances sensitivity of human hepatocellular carcinoma cells to radiotherapy in vitro and in a xenograft model. PLoS ONE. 2013;8:e55313 pubmed 出版商 |
Chen S, Xiong G, Wu S, Mo J. Downregulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 enhances the sensitivity of human pancreatic cancer cells to radiotherapy in vitro. Cancer Biother Radiopharm. 2013;28:169-76 pubmed 出版商 |
Yang Z, Misner B, Ji H, Poulos T, Silverman R, Meyskens F, et al. Targeting nitric oxide signaling with nNOS inhibitors as a novel strategy for the therapy and prevention of human melanoma. Antioxid Redox Signal. 2013;19:433-47 pubmed 出版商 |
Linke M, May A, Reifenberg K, Haaf T, Zechner U. The impact of ovarian stimulation on the expression of candidate reprogramming genes in mouse preimplantation embryos. Cytogenet Genome Res. 2013;139:71-9 pubmed 出版商 |
Corniola R, Zou Y, Leu D, Fike J, Huang T. Paradoxical relationship between Mn superoxide dismutase deficiency and radiation-induced cognitive defects. PLoS ONE. 2012;7:e49367 pubmed 出版商 |
Singh S, Englander E. Nuclear depletion of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) is an indicator of energy disruption in neurons. Free Radic Biol Med. 2012;53:1782-90 pubmed 出版商 |
Cai X, Wang J, Xin X. CIAPIN1 nuclear accumulation predicts poor clinical outcome in epithelial ovarian cancer. World J Surg Oncol. 2012;10:112 pubmed 出版商 |
Hill J, Poddar R, Thompson J, Rosenberg G, Yang Y. Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons. Neuroscience. 2012;220:277-90 pubmed 出版商 |
Siddiqui A, Rivera Sánchez S, Castro M, Acevedo Torres K, Rane A, Torres Ramos C, et al. Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease. Free Radic Biol Med. 2012;53:1478-88 pubmed 出版商 |
Clark D, Phang T, Edwards M, Geraci M, Gillespie M. Promoter G-quadruplex sequences are targets for base oxidation and strand cleavage during hypoxia-induced transcription. Free Radic Biol Med. 2012;53:51-9 pubmed 出版商 |
Li M, Vascotto C, Xu S, Dai N, Qing Y, Zhong Z, et al. Human AP endonuclease/redox factor APE1/ref-1 modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1. Free Radic Biol Med. 2012;53:237-48 pubmed 出版商 |
Mantha A, Dhiman M, Taglialatela G, Perez Polo R, Mitra S. Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction. J Neurosci Res. 2012;90:1230-9 pubmed 出版商 |
Sengupta S, Chattopadhyay R, Mantha A, Mitra S, Bhakat K. Regulation of mouse-renin gene by apurinic/apyrimidinic-endonuclease 1 (APE1/Ref-1) via recruitment of histone deacetylase 1 corepressor complex. J Hypertens. 2012;30:917-25 pubmed 出版商 |
Castro M, Suarez E, Kraiselburd E, Isidro A, Paz J, Ferder L, et al. Aging increases mitochondrial DNA damage and oxidative stress in liver of rhesus monkeys. Exp Gerontol. 2012;47:29-37 pubmed 出版商 |
Kim Y, Kim D, Illuzzi J, Delaplane S, Su D, Bernier M, et al. S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity. J Mol Biol. 2011;414:313-26 pubmed 出版商 |
Weis E, Schoen H, Victor A, Spix C, Ludwig M, Schneider Raetzke B, et al. Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer. PLoS ONE. 2011;6:e25750 pubmed 出版商 |
Zhang Z, Yang X, Wang D, Wang G, Yang Z, Qing Y, et al. Nm23-H1 protein binds to APE1 at AP sites and stimulates AP endonuclease activity following ionizing radiation of the human lung cancer A549 cells. Cell Biochem Biophys. 2011;61:561-72 pubmed 出版商 |
Singh Gupta V, Joiner M, Runyan L, Yunker C, Sarkar F, Miller S, et al. Soy isoflavones augment radiation effect by inhibiting APE1/Ref-1 DNA repair activity in non-small cell lung cancer. J Thorac Oncol. 2011;6:688-98 pubmed 出版商 |
Jaiswal A, Narayan S. Assembly of the base excision repair complex on abasic DNA and role of adenomatous polyposis coli on its functional activity. Biochemistry. 2011;50:1901-9 pubmed 出版商 |
Bobola M, Jankowski P, Gross M, Schwartz J, Finn L, Blank A, et al. Apurinic/apyrimidinic endonuclease is inversely associated with response to radiotherapy in pediatric ependymoma. Int J Cancer. 2011;129:2370-9 pubmed 出版商 |
Karimi Busheri F, Rasouli Nia A, Mackey J, Weinfeld M. Senescence evasion by MCF-7 human breast tumor-initiating cells. Breast Cancer Res. 2010;12:R31 pubmed 出版商 |
Warters R, Cassidy P, Sunseri J, Parsawar K, Zhuplatov S, Kramer G, et al. The nuclear matrix shell proteome of human epidermis. J Dermatol Sci. 2010;58:113-22 pubmed 出版商 |
Chattopadhyay R, Bhattacharyya A, Crowe S. Dual regulation by apurinic/apyrimidinic endonuclease-1 inhibits gastric epithelial cell apoptosis during Helicobacter pylori infection. Cancer Res. 2010;70:2799-808 pubmed 出版商 |
Jelezcova E, Trivedi R, Wang X, Tang J, Brown A, Goellner E, et al. Parp1 activation in mouse embryonic fibroblasts promotes Pol beta-dependent cellular hypersensitivity to alkylation damage. Mutat Res. 2010;686:57-67 pubmed 出版商 |
Ray S, Lee C, Hou T, Bhakat K, Brasier A. Regulation of signal transducer and activator of transcription 3 enhanceosome formation by apurinic/apyrimidinic endonuclease 1 in hepatic acute phase response. Mol Endocrinol. 2010;24:391-401 pubmed 出版商 |
Jones L, Ying L, Hofseth A, Jelezcova E, Sobol R, Ambs S, et al. Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase. Carcinogenesis. 2009;30:2123-9 pubmed 出版商 |
Batuello C, Kelley M, Dynlacht J. Role of Ape1 and base excision repair in the radioresponse and heat-radiosensitization of HeLa Cells. Anticancer Res. 2009;29:1319-25 pubmed |
Unnikrishnan A, Raffoul J, Patel H, Prychitko T, Anyangwe N, Meira L, et al. Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice. Free Radic Biol Med. 2009;46:1488-99 pubmed 出版商 |
Chattopadhyay R, Das S, Maiti A, Boldogh I, Xie J, Hazra T, et al. Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1. Mol Cell Biol. 2008;28:7066-80 pubmed 出版商 |
May A, Kirchner R, Muller H, Hartmann P, El Hajj N, Tresch A, et al. Multiplex rt-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeres. Biol Reprod. 2009;80:194-202 pubmed 出版商 |
Breit J, Ault Ziel K, Al Mehdi A, Gillespie M. Nuclear protein-induced bending and flexing of the hypoxic response element of the rat vascular endothelial growth factor promoter. FASEB J. 2008;22:19-29 pubmed |
Yang S, Misner B, Chiu R, Meyskens F. Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells. Carcinogenesis. 2007;28:2382-90 pubmed |
Lam W, Leung C, Bussom S, Cheng Y. The impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine. Mol Pharmacol. 2007;72:536-44 pubmed |
Kundu C, Balusu R, Jaiswal A, Narayan S. Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: implication of base excision repair pathways. Carcinogenesis. 2007;28:2089-95 pubmed |
Maki A, Kono H, Gupta M, Asakawa M, Suzuki T, Matsuda M, et al. Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma. Ann Surg Oncol. 2007;14:1182-90 pubmed |
Lam W, Park S, Leung C, Cheng Y. Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (g. Mol Pharmacol. 2006;69:1607-14 pubmed |
Yang S, Irani K, Heffron S, Jurnak F, Meyskens F. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor. Mol Cancer Ther. 2005;4:1923-35 pubmed |
Bobola M, Finn L, Ellenbogen R, Geyer J, Berger M, Braga J, et al. Apurinic/apyrimidinic endonuclease activity is associated with response to radiation and chemotherapy in medulloblastoma and primitive neuroectodermal tumors. Clin Cancer Res. 2005;11:7405-14 pubmed |
Ziel K, Grishko V, Campbell C, Breit J, Wilson G, Gillespie M. Oxidants in signal transduction: impact on DNA integrity and gene expression. FASEB J. 2005;19:387-94 pubmed |
Elchuri S, Oberley T, Qi W, Eisenstein R, Jackson Roberts L, Van Remmen H, et al. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene. 2005;24:367-80 pubmed |
Cabelof D, Raffoul J, Nakamura J, Kapoor D, Abdalla H, Heydari A. Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency. J Biol Chem. 2004;279:36504-13 pubmed |
Wang D, Luo M, Kelley M. Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition. Mol Cancer Ther. 2004;3:679-86 pubmed |
Marenstein D, Wilson D, Teebor G. Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA. DNA Repair (Amst). 2004;3:527-33 pubmed |
Raffoul J, Cabelof D, Nakamura J, Meira L, Friedberg E, Heydari A. Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair. J Biol Chem. 2004;279:18425-33 pubmed |
Shen G, Galick H, Inoue M, Wallace S. Decline of nuclear and mitochondrial oxidative base excision repair activity in late passage human diploid fibroblasts. DNA Repair (Amst). 2003;2:673-93 pubmed |
Fishel M, Seo Y, Smith M, Kelley M. Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing. Cancer Res. 2003;63:608-15 pubmed |
Seo Y, Fishel M, Amundson S, Kelley M, Smith M. Implication of p53 in base excision DNA repair: in vivo evidence. Oncogene. 2002;21:731-7 pubmed |
Thomson B, Tritt R, Davis M, Kelley M. Histology-specific expression of a DNA repair protein in pediatric rhabdomyosarcomas. J Pediatr Hematol Oncol. 2001;23:234-9 pubmed |
Park S, Lam W, Cheng Y. X-ray repair cross-complementing gene I protein plays an important role in camptothecin resistance. Cancer Res. 2002;62:459-65 pubmed |
Schindl M, Oberhuber G, Pichlbauer E, Obermair A, Birner P, Kelley M. DNA repair-redox enzyme apurinic endonuclease in cervical cancer: evaluation of redox control of HIF-1alpha and prognostic significance. Int J Oncol. 2001;19:799-802 pubmed |
Kelley M, Cheng L, Foster R, Tritt R, Jiang J, Broshears J, et al. Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer. Clin Cancer Res. 2001;7:824-30 pubmed |
Robertson K, Bullock H, Xu Y, Tritt R, Zimmerman E, Ulbright T, et al. Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation. Cancer Res. 2001;61:2220-5 pubmed |
Thomson B, Tritt R, Davis M, Perlman E, Kelley M. Apurinic/apyrimidinic endonuclease expression in pediatric yolk sac tumors. Anticancer Res. 2000;20:4153-7 pubmed |
Chou K, Kukhanova M, Cheng Y. A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3' termini of DNA. J Biol Chem. 2000;275:31009-15 pubmed |
Moore D, Michael H, Tritt R, Parsons S, Kelley M. Alterations in the expression of the DNA repair/redox enzyme APE/ref-1 in epithelial ovarian cancers. Clin Cancer Res. 2000;6:602-9 pubmed |
