产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
NFATC2/NFAT1抗体(25A10.D6.D2)
目录 :
NB300-504
规格 :
100 ug (also 0.025 mg)
价格 :
329美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
25A10.D6.D2
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 大鼠; 1:100; 图 3f
Liu J, Han Z, Han Z, He Z. Mesenchymal stem cell-conditioned media suppresses inflammation-associated overproliferation of pulmonary artery smooth muscle cells in a rat model of pulmonary hypertension. Exp Ther Med. 2016;11:467-475 pubmed
Li Z, Jiang L, Chew S, Hirayama T, Sekido Y, Toyokuni S. Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia. Redox Biol. 2019;26:101297 pubmed 出版商
Song S, Carr S, McDermott K, Rodriguez M, Babicheva A, Balistrieri A, et al. STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension. Hypertension. 2018;71:518-529 pubmed 出版商
Kelly N, Varga J, Specker E, Romeo C, Coomber B, Uniacke J. Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion. Oncogene. 2018;37:651-662 pubmed 出版商
Younan P, Iampietro M, Nishida A, Ramanathan P, Santos R, Dutta M, et al. Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm. MBio. 2017;8: pubmed 出版商
Jin H, Wang C, Jin G, Ruan H, Gu D, Wei L, et al. Regulator of Calcineurin 1 Gene Isoform 4, Down-regulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Metastasis of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1. Gastroenterology. 2017;153:799-811.e33 pubmed 出版商
Federici C, Lugini L, Marino M, Carta F, Iessi E, Azzarito T, et al. Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells. J Enzyme Inhib Med Chem. 2016;31:119-125 pubmed
Cotroneo E, Ashek A, Wang L, Wharton J, Dubois O, Bozorgi S, et al. Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat. Circ Res. 2015;116:1680-90 pubmed 出版商
Cai C, Alshehri A, Choksi R, Pestronk A. Regional ischemic immune myopathy: a paraneoplastic dermatomyopathy. J Neuropathol Exp Neurol. 2014;73:1126-33 pubmed 出版商
Iampietro M, Morissette G, Gravel A, Flamand L. Inhibition of interleukin-2 gene expression by human herpesvirus 6B U54 tegument protein. J Virol. 2014;88:12452-63 pubmed 出版商
Persano L, Pistollato F, Rampazzo E, Della Puppa A, Abbadi S, Frasson C, et al. BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1? stability and MGMT expression. Cell Death Dis. 2012;3:e412 pubmed 出版商
Landry J, Banerjee S, Taylor B, Aplan P, Singer A, Wu C. Chromatin remodeling complex NURF regulates thymocyte maturation. Genes Dev. 2011;25:275-86 pubmed 出版商
Alpini G, Franchitto A, Demorrow S, Onori P, Gaudio E, Wise C, et al. Activation of alpha(1) -adrenergic receptors stimulate the growth of small mouse cholangiocytes via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1. Hepatology. 2011;53:628-39 pubmed 出版商
Barlic J, McDermott D, Merrell M, Gonzales J, Via L, Murphy P. Interleukin (IL)-15 and IL-2 reciprocally regulate expression of the chemokine receptor CX3CR1 through selective NFAT1- and NFAT2-dependent mechanisms. J Biol Chem. 2004;279:48520-34 pubmed
图像
图像 1 :
Novus Biologicals NB300-504 图像 1
Immunocytochemistry/Immunofluorescence: NFATC2/NFAT1 Antibody (25A10.D6.D2) [NB300-504] - Analysis of NFATc2 (green) in HeLa cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were left untreated (left panel) or treated with 1uM staurosporine (right panel) for 3 hours and probed with a NFATc2 monoclonal antibody, at a dilution of 1:100 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488 goat anti-mouse IgG secondary antibody at a dilution of 1:400 for 30 minutes at room temperature. F-Actin (red) was stained with DyLight 554 Phalloidin and nuclei (blue) were stained with Hoechst 33342 dye.
产品信息
品牌 :
Novus
master code :
NB300-504
SKU号 :
NB300-504
产品名称 :
NFATC2/NFAT1抗体(25A10.D6.D2)
描述 :
The NFATC2/NFAT1 Antibody (25A10.D6.D2) from Novus Biologicals is a mouse monoclonal antibody to NFATC2/NFAT1. This antibody reacts with human, mouse, rat. The NFATC2/NFAT1 Antibody (25A10.D6.D2) has been validated for the following applications: Western Blot, Chromatin Immunoprecipitation, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Gel Super Shift Assays, Sandwich ELISA.
靶标 :
NFATC2/NFAT1
类别 :
一抗
单位尺寸 :
100 ug (also 0.025 mg)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
25A10.D6.D2
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Synthetic peptide corresponding to residues A(51) I S S P S G L A Y P D D V L D Y G L(69) of mouse NFATc2-A, B and C isoforms.
抗体亚型 :
IgG1
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠
特异性 :
Detects nuclear factor of activated T-cells (NFAT). This does not cross react with NFAT2 (NFATc, NFATc1).
理论上的分子量 :
140 kDa
基因符号 :
NFATC2
catalog number base :
NB300-504
应用 :
Western Blot, Chromatin Immunoprecipitation, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Gel Super Shift Assays, Sandwich ELISA
2020美元 :
329
2021美元 :
329美元
别名 :
NFAT pre-existing subunit, NFAT transcription complex, preexisting component, NFAT1nuclear factor of activated T-cells, cytoplasmic 2, NFATc2, NF-ATc2, NFATp, NF-ATp, NFATPnuclear factor of activated T-cells, preexisting component, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2, preexisting nuclear factor of activated T-cells 2, T cell transcription factor NFAT1, T-cell transcription factor NFAT1
储存 :
存放在-20C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。