产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
ABCA1抗体
目录 :
NB400-105
规格 :
0.1 ml (also 0.025 ml)
价格 :
349美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
仓鼠, 人类, 小鼠, 大鼠, , ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 中和反应, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 310
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 5b
Casali B, Reed Geaghan E, Landreth G. Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer's disease. J Neuroinflammation. 2018;15:43 pubmed 出版商
  • 免疫印迹; 人类; 图 5d
  • 免疫印迹; 小鼠; 图 6d
Nelson J, Koenis D, Scheij S, Cook E, Moeton M, Santos A, et al. EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux. Arterioscler Thromb Vasc Biol. 2017;37:423-432 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3a
Wang L, Palme V, Rotter S, Schilcher N, Cukaj M, Wang D, et al. Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages. Mol Nutr Food Res. 2017;61: pubmed 出版商
  • 免疫印迹; 牛; 1:1000; 表 2
Ontsouka C, Huang X, Aliyev E, Albrecht C. In vitro characterization and endocrine regulation of cholesterol and phospholipid transport in the mammary gland. Mol Cell Endocrinol. 2017;439:35-45 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s5a
Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed 出版商
  • 免疫印迹; 大鼠; 图 4
Zinkhan E, Zalla J, Carpenter J, Yu B, Yu X, Chan G, et al. Intrauterine growth restriction combined with a maternal high-fat diet increases hepatic cholesterol and low-density lipoprotein receptor activity in rats. Physiol Rep. 2016;4: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
Hsieh J, Koseki M, Molusky M, Yakushiji E, Ichi I, Westerterp M, et al. TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis. Nature. 2016;535:303-7 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
  • 免疫印迹; 小鼠; 1:1000; 图 3
Fournier N, Tardivel S, Benoist J, Vedie B, Rousseau Ralliard D, Nowak M, et al. Eicosapentaenoic acid membrane incorporation impairs ABCA1-dependent cholesterol efflux via a protein kinase A signaling pathway in primary human macrophages. Biochim Biophys Acta. 2016;1861:331-41 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2c
Hussein M, Shrestha E, Ouimet M, Barrett T, Leone S, Moore K, et al. LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2. PLoS ONE. 2015;10:e0135218 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Ito A, Hong C, Rong X, Zhu X, Tarling E, Hedde P, et al. LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling. elife. 2015;4:e08009 pubmed 出版商
  • 免疫印迹; 小鼠
Baker A, Watt J, Huang C, Gerstenfeld L, Schlezinger J. Tributyltin engages multiple nuclear receptor pathways and suppresses osteogenesis in bone marrow multipotent stromal cells. Chem Res Toxicol. 2015;28:1156-66 pubmed 出版商
  • 免疫印迹; 大鼠
Liu Q, Li J, Liang Q, Wang D, Luo Y, Yu F, et al. Sparstolonin B suppresses rat vascular smooth muscle cell proliferation, migration, inflammatory response and lipid accumulation. Vascul Pharmacol. 2015;67-69:59-66 pubmed 出版商
  • 免疫印迹; 小鼠
de Boussac H, Maqdasy S, Trousson A, Zelcer N, Volle D, Lobaccaro J, et al. Enolase is regulated by Liver X Receptors. Steroids. 2015;99:266-71 pubmed 出版商
  • 免疫印迹; 小鼠
Park S, Paek J, Shin D, Lee J, Lim S, Kang Y. Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages. Int J Mol Med. 2015;35:957-65 pubmed 出版商
  • 免疫印迹; 仓鼠
Dong F, Mo Z, Eid W, Courtney K, Zha X. Akt inhibition promotes ABCA1-mediated cholesterol efflux to ApoA-I through suppressing mTORC1. PLoS ONE. 2014;9:e113789 pubmed 出版商
  • 免疫印迹; 小鼠
Shibuya Y, Chang C, Huang L, Bryleva E, Chang T. Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance. J Neurosci. 2014;34:14484-501 pubmed 出版商
  • 免疫印迹; 人类
Liu W, Jiang J, Yan D, Li D, Li W, Ma Y, et al. Pentraxin 3 promotes oxLDL uptake and inhibits cholesterol efflux from macrophage-derived foam cells. Exp Mol Pathol. 2014;96:292-9 pubmed 出版商
  • 免疫印迹; 小鼠
Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain B, et al. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. J Lipid Res. 2014;55:1120-30 pubmed 出版商
  • 免疫印迹; 人类
Bocchetta S, Maillard P, Yamamoto M, Gondeau C, Douam F, Lebreton S, et al. Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection. PLoS ONE. 2014;9:e92140 pubmed 出版商
  • 免疫印迹; 小鼠
Du R, Qin S, Shi L, Zhou Z, Zhu X, Liu J, et al. Fumigaclavine C activates PPAR? pathway and attenuates atherogenesis in ApoE-deficient mice. Atherosclerosis. 2014;234:120-8 pubmed 出版商
  • 免疫组化-石蜡切片; 狗
  • 免疫细胞化学; 狗
Palme N, Becher A, Merkl M, Glösmann M, Aurich C, Schäfer Somi S. Immunolocalization of the cholesterol transporters ABCA1 and ABCG1 in canine reproductive tract tissues and spermatozoa. Reprod Domest Anim. 2014;49:441-7 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
Vinod M, Chennamsetty I, Colin S, Belloy L, De Paoli F, Schaider H, et al. miR-206 controls LXR? expression and promotes LXR-mediated cholesterol efflux in macrophages. Biochim Biophys Acta. 2014;1841:827-35 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Allahverdian S, Chehroudi A, McManus B, Abraham T, Francis G. Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis. Circulation. 2014;129:1551-9 pubmed 出版商
  • 免疫印迹; 人类
Okabe A, Urano Y, Itoh S, Suda N, Kotani R, Nishimura Y, et al. Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death. Redox Biol. 2013;2:28-35 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
Li N, Xu Y, Feng T, Liu C, Li Y, Wang X, et al. Identification of a selective agonist for liver X receptor ? (LXR?) via screening of a synthetic compound library. J Biomol Screen. 2014;19:566-74 pubmed 出版商
  • 免疫印迹; 小鼠
Ying R, Yuan Y, Qin Y, Tian D, Feng L, Guo Z, et al. The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice. Lipids Health Dis. 2013;12:180 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Horie T, Nishino T, Baba O, Kuwabara Y, Nakao T, Nishiga M, et al. MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice. Nat Commun. 2013;4:2883 pubmed 出版商
  • 免疫印迹; 小鼠
Yu F, Du F, Wang Y, Huang S, Miao R, Major A, et al. Bone marrow deficiency of MCPIP1 results in severe multi-organ inflammation but diminishes atherogenesis in hyperlipidemic mice. PLoS ONE. 2013;8:e80089 pubmed 出版商
  • 免疫印迹; 小鼠
Ohara K, Wakabayashi H, Taniguchi Y, Shindo K, Yajima H, Yoshida A. Quercetin-3-O-glucuronide induces ABCA1 expression by LXR? activation in murine macrophages. Biochem Biophys Res Commun. 2013;441:929-34 pubmed 出版商
  • 免疫印迹; 人类
Baumann M, Korner M, Huang X, Wenger F, Surbek D, Albrecht C. Placental ABCA1 and ABCG1 expression in gestational disease: Pre-eclampsia affects ABCA1 levels in syncytiotrophoblasts. Placenta. 2013;34:1079-86 pubmed 出版商
  • 免疫印迹; 小鼠
Hu Y, Yang Y, Yu Y, Wen G, Shang N, Zhuang W, et al. Synthesis and identification of new flavonoids targeting liver X receptor ? involved pathway as potential facilitators of A? clearance with reduced lipid accumulation. J Med Chem. 2013;56:6033-53 pubmed 出版商
  • 免疫印迹; 人类
Shao F, Ford D. Differential regulation of ABCA1 and macrophage cholesterol efflux by elaidic and oleic acids. Lipids. 2013;48:757-67 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
A Gonzalez N, Guillen J, Gallardo G, Diaz M, de la Rosa J, Hernandez I, et al. The nuclear receptor LXR? controls the functional specialization of splenic macrophages. Nat Immunol. 2013;14:831-9 pubmed 出版商
  • 免疫印迹; 人类
Sorrentino V, Nelson J, Maspero E, Marques A, Scheer L, Polo S, et al. The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation. J Lipid Res. 2013;54:2174-84 pubmed 出版商
  • 免疫印迹; 人类
Ignatova I, Angdisen J, Moran E, Schulman I. Differential regulation of gene expression by LXRs in response to macrophage cholesterol loading. Mol Endocrinol. 2013;27:1036-47 pubmed 出版商
  • 免疫印迹; 小鼠
Pommier A, Dufour J, Alves G, Viennois E, de Boussac H, Trousson A, et al. Liver x receptors protect from development of prostatic intra-epithelial neoplasia in mice. PLoS Genet. 2013;9:e1003483 pubmed 出版商
  • 免疫细胞化学; 小鼠
Lim H, Thiam C, Yeo K, Bisoendial R, Hii C, McGrath K, et al. Lymphatic vessels are essential for the removal of cholesterol from peripheral tissues by SR-BI-mediated transport of HDL. Cell Metab. 2013;17:671-84 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 仓鼠
Mulay V, Wood P, Manetsch M, Darabi M, Cairns R, Hoque M, et al. Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells. PLoS ONE. 2013;8:e62667 pubmed 出版商
  • 免疫印迹; 小鼠
Dufour J, Pommier A, Alves G, de Boussac H, Lours Calet C, Volle D, et al. Lack of liver X receptors leads to cell proliferation in a model of mouse dorsal prostate epithelial cell. PLoS ONE. 2013;8:e58876 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
  • 免疫印迹; 小鼠
Béaslas O, Metso J, Nissilä E, Laurila P, Kaiharju E, Batchu K, et al. Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism. PLoS ONE. 2013;8:e58856 pubmed 出版商
  • 免疫组化; 人类
  • 免疫印迹; 人类
Lo Sasso G, Bovenga F, Murzilli S, Salvatore L, Di Tullio G, Martelli N, et al. Liver X receptors inhibit proliferation of human colorectal cancer cells and growth of intestinal tumors in mice. Gastroenterology. 2013;144:1497-507, 1507.e1-13 pubmed 出版商
  • 免疫印迹; 人类
Scotti E, Calamai M, Goulbourne C, Zhang L, Hong C, Lin R, et al. IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor. Mol Cell Biol. 2013;33:1503-14 pubmed 出版商
  • 免疫印迹; 小鼠
Khan O, Akula M, Skålén K, Karlsson C, Ståhlman M, Young S, et al. Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice. Circulation. 2013;127:782-90 pubmed 出版商
  • 免疫印迹; 小鼠
Horie T, Baba O, Kuwabara Y, Chujo Y, Watanabe S, Kinoshita M, et al. MicroRNA-33 deficiency reduces the progression of atherosclerotic plaque in ApoE-/- mice. J Am Heart Assoc. 2012;1:e003376 pubmed 出版商
  • 免疫印迹; 人类
Ishibashi M, Filomenko R, Rébé C, Chevriaux A, Varin A, Derangère V, et al. Knock-down of the oxysterol receptor LXR? impairs cholesterol efflux in human primary macrophages: lack of compensation by LXR? activation. Biochem Pharmacol. 2013;86:122-9 pubmed 出版商
  • 免疫印迹; 人类
Liu X, Lu Q, Ouyang X, Tang S, Zhao G, Lv Y, et al. Apelin-13 increases expression of ATP-binding cassette transporter A1 via activating protein kinase C ? signaling in THP-1 macrophage-derived foam cells. Atherosclerosis. 2013;226:398-407 pubmed 出版商
  • 免疫印迹; 小鼠
Park D, Lee H, Lyu J, Chin H, Kang S, Kim Y, et al. TLR2 stimulates ABCA1 expression via PKC-? and PLD2 pathway. Biochem Biophys Res Commun. 2013;430:933-7 pubmed 出版商
  • 免疫印迹; 人类
Lee B, Taylor M, Robinet P, Smith J, Schweitzer J, Sehayek E, et al. Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1. Cancer Res. 2013;73:1211-8 pubmed 出版商
  • 免疫印迹; 小鼠
Dominguez J, Xie Y, Dunne W, Yoseph B, Burd E, Coopersmith C, et al. Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a murine model of Pseudomonas aeruginosa pneumonia. PLoS ONE. 2012;7:e49159 pubmed 出版商
  • 免疫印迹; 小鼠
Maitra U, Li L. Molecular mechanisms responsible for the reduced expression of cholesterol transporters from macrophages by low-dose endotoxin. Arterioscler Thromb Vasc Biol. 2013;33:24-33 pubmed 出版商
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
Cardilo Reis L, Gruber S, Schreier S, Drechsler M, Papac Milicevic N, Weber C, et al. Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype. EMBO Mol Med. 2012;4:1072-86 pubmed 出版商
  • 免疫细胞化学; 人类
Machado Lima A, Iborra R, Pinto R, Sartori C, Oliveira E, Nakandakare E, et al. Advanced glycated albumin isolated from poorly controlled type 1 diabetes mellitus patients alters macrophage gene expression impairing ABCA-1-mediated reverse cholesterol transport. Diabetes Metab Res Rev. 2013;29:66-76 pubmed 出版商
  • 免疫印迹; 小鼠
Zhou Q, Mei Y, Shoji T, Han X, Kaminski K, Oh G, et al. Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis. Circulation. 2012;126:2236-47 pubmed 出版商
  • 免疫印迹; 大鼠
Chen J, Zhang X, Kusumo H, Costa L, Guizzetti M. Cholesterol efflux is differentially regulated in neurons and astrocytes: implications for brain cholesterol homeostasis. Biochim Biophys Acta. 2013;1831:263-75 pubmed 出版商
  • 免疫印迹; 人类
Peter C, Waibel M, Keppeler H, Lehmann R, Xu G, Halama A, et al. Release of lysophospholipid 'find-me' signals during apoptosis requires the ATP-binding cassette transporter A1. Autoimmunity. 2012;45:568-73 pubmed 出版商
  • 免疫印迹; 小鼠
Mandrekar Colucci S, Karlo J, Landreth G. Mechanisms underlying the rapid peroxisome proliferator-activated receptor-?-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease. J Neurosci. 2012;32:10117-28 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 免疫细胞化学; 小鼠
  • 免疫组化; 小鼠
Machado R, Nakandakare E, Quintao E, Cazita P, Koike M, Nunes V, et al. Omega-6 polyunsaturated fatty acids prevent atherosclerosis development in LDLr-KO mice, in spite of displaying a pro-inflammatory profile similar to trans fatty acids. Atherosclerosis. 2012;224:66-74 pubmed 出版商
  • 免疫印迹; 人类
Allen R, Marquart T, Albert C, Suchy F, Wang D, Ananthanarayanan M, et al. miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity. EMBO Mol Med. 2012;4:882-95 pubmed 出版商
  • 免疫细胞化学; 大鼠
  • 免疫印迹; 大鼠
Xia X, Jung D, Webb P, Zhang A, Zhang B, Li L, et al. Liver X receptor ? and peroxisome proliferator-activated receptor ? regulate cholesterol transport in murine cholangiocytes. Hepatology. 2012;56:2288-96 pubmed 出版商
  • 免疫细胞化学; 人类
Noghero A, Perino A, Seano G, Saglio E, Lo Sasso G, Veglio F, et al. Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2. Arterioscler Thromb Vasc Biol. 2012;32:2280-8 pubmed 出版商
  • 免疫组化; 人类
Luo Z, Li J, Nabar N, Lin X, Bai G, Cai J, et al. Efficacy of a therapeutic vaccine using mutated ?-amyloid sensitized dendritic cells in Alzheimer's mice. J Neuroimmune Pharmacol. 2012;7:640-55 pubmed 出版商
  • 免疫印迹; 小鼠
Okada Y, Ueyama K, Nishikawa J, Semma M, Ichikawa A. Effect of 6-O-?-maltosyl-? cyclodextrin and its cholesterol inclusion complex on cellular cholesterol levels and ABCA1 and ABCG1 expression in mouse mastocytoma P-815 cells. Carbohydr Res. 2012;357:68-74 pubmed 出版商
  • 免疫细胞化学; 人类
Cox J, Naher N, Abdelrahman Y, Belland R. Host HDL biogenesis machinery is recruited to the inclusion of Chlamydia trachomatis-infected cells and regulates chlamydial growth. Cell Microbiol. 2012;14:1497-512 pubmed 出版商
  • 免疫印迹; 小鼠
Scheffler K, Krohn M, Dunkelmann T, Stenzel J, Miroux B, Ibrahim S, et al. Mitochondrial DNA polymorphisms specifically modify cerebral ?-amyloid proteostasis. Acta Neuropathol. 2012;124:199-208 pubmed 出版商
  • 免疫印迹; 人类
Tang S, Chen W, Yin K, Zhao G, Mo Z, Lv Y, et al. PAPP-A negatively regulates ABCA1, ABCG1 and SR-B1 expression by inhibiting LXR? through the IGF-I-mediated signaling pathway. Atherosclerosis. 2012;222:344-54 pubmed 出版商
  • 免疫细胞化学; 小鼠
Castilho G, Okuda L, Pinto R, Iborra R, Nakandakare E, Santos C, et al. ER stress is associated with reduced ABCA-1 protein levels in macrophages treated with advanced glycated albumin - reversal by a chemical chaperone. Int J Biochem Cell Biol. 2012;44:1078-86 pubmed 出版商
  • 免疫印迹; 人类
Iio A, Ohguchi K, Iinuma M, Nozawa Y, Ito M. Hesperetin upregulates ABCA1 expression and promotes cholesterol efflux from THP-1 macrophages. J Nat Prod. 2012;75:563-6 pubmed 出版商
  • 免疫印迹; 人类
Morbitzer D, Namgaladze D, Brüne B. Phospholipase A(2)-modified low-density lipoprotein activates liver X receptor in human macrophages. Cell Biochem Biophys. 2012;63:143-9 pubmed 出版商
  • 免疫印迹; 小鼠
Storey S, McIntosh A, Huang H, Landrock K, Martin G, Landrock D, et al. Intracellular cholesterol-binding proteins enhance HDL-mediated cholesterol uptake in cultured primary mouse hepatocytes. Am J Physiol Gastrointest Liver Physiol. 2012;302:G824-39 pubmed 出版商
  • 免疫印迹; 小鼠
Nagashima M, Watanabe T, Terasaki M, Tomoyasu M, Nohtomi K, Kim Kaneyama J, et al. Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice. Diabetologia. 2011;54:2649-59 pubmed 出版商
  • 免疫印迹; 仓鼠
Lee J, Karwatsky J, Ma L, Zha X. ABCA1 increases extracellular ATP to mediate cholesterol efflux to ApoA-I. Am J Physiol Cell Physiol. 2011;301:C886-94 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
McLaren J, Michael D, Salter R, Ashlin T, Calder C, Miller A, et al. IL-33 reduces macrophage foam cell formation. J Immunol. 2010;185:1222-9 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
Yang H, Chen K, Zhang X, Wang L, Li C, Tao H, et al. Vitamin A deficiency results in dysregulation of lipid efflux pathway in rat kidney. Pediatr Nephrol. 2010;25:1435-44 pubmed 出版商
  • 免疫印迹; 人类
Xue J, Yuan Z, Wu Y, Liu Y, Zhao Y, Zhang W, et al. High glucose promotes intracellular lipid accumulation in vascular smooth muscle cells by impairing cholesterol influx and efflux balance. Cardiovasc Res. 2010;86:141-50 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 大鼠
Zhang Y, Yin L, Anderson J, Ma H, Gonzalez F, Willson T, et al. Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia. J Biol Chem. 2010;285:3035-43 pubmed 出版商
  • 免疫印迹; 人类
Scoles D, Xu X, Wang H, Tran H, Taylor Harding B, Li A, et al. Liver X receptor agonist inhibits proliferation of ovarian carcinoma cells stimulated by oxidized low density lipoprotein. Gynecol Oncol. 2010;116:109-16 pubmed 出版商
Hennessy E, van Solingen C, Scacalossi K, Ouimet M, Afonso M, Prins J, et al. The long noncoding RNA CHROME regulates cholesterol homeostasis in primate. Nat Metab. 2019;1:98-110 pubmed 出版商
Zhou Y, Bazick H, Miles J, Fethiere A, Salihi M, Fazio S, et al. A neutral lipid-enriched diet improves myelination and alleviates peripheral nerve pathology in neuropathic mice. Exp Neurol. 2019;321:113031 pubmed 出版商
Paul A, Lydic T, Hogan R, Goo Y. Cholesterol Acceptors Regulate the Lipidome of Macrophage Foam Cells. Int J Mol Sci. 2019;20: pubmed 出版商
Mukhamedova N, Hoang A, Dragoljevic D, Dubrovsky L, Pushkarsky T, Low H, et al. Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. PLoS Pathog. 2019;15:e1007907 pubmed 出版商
Koyama S, Horie T, Nishino T, Baba O, Sowa N, Miyasaka Y, et al. Identification of Differential Roles of MicroRNA-33a and -33b During Atherosclerosis Progression With Genetically Modified Mice. J Am Heart Assoc. 2019;8:e012609 pubmed 出版商
Rege S, Royes L, Tsai B, Zhang G, Yang X, Gomez Pinilla F. Brain Trauma Disrupts Hepatic Lipid Metabolism: Blame It on Fructose?. Mol Nutr Food Res. 2019;63:e1801054 pubmed 出版商
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Dove D, Su Y, Zhang W, Jerome W, Swift L, Linton M, et al. ACAT1 deficiency disrupts cholesterol efflux and alters cellular morphology in macrophages. Arterioscler Thromb Vasc Biol. 2005;25:128-34 pubmed
O Connell B, Denis M, Genest J. Cellular physiology of cholesterol efflux in vascular endothelial cells. Circulation. 2004;110:2881-8 pubmed
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Zeng L, Liao H, Liu Y, Lee T, Zhu M, Wang X, et al. Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism. J Biol Chem. 2004;279:48801-7 pubmed
Denis M, Haidar B, Marcil M, Bouvier M, Krimbou L, Genest J. Characterization of oligomeric human ATP binding cassette transporter A1. Potential implications for determining the structure of nascent high density lipoprotein particles. J Biol Chem. 2004;279:41529-36 pubmed
Ando H, Tsuruoka S, Yamamoto H, Takamura T, Kaneko S, Fujimura A. Effects of pravastatin on the expression of ATP-binding cassette transporter A1. J Pharmacol Exp Ther. 2004;311:420-5 pubmed
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Field F, Born E, Mathur S. LXR/RXR ligand activation enhances basolateral efflux of beta-sitosterol in CaCo-2 cells. J Lipid Res. 2004;45:905-13 pubmed
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产品信息
SKU号 :
NB400-105
产品名称 :
ABCA1抗体
单位尺寸 :
0.1 ml (also 0.025 ml)
描述 :
The ABCA1 Antibody from Novus is a rabbit polyclonal antibody to ABCA1. This antibody reacts with human, mouse, rat, porcine, canine, chicken, chinese hamster, equine, hamster, mustelid, primate, rabbit. The ABCA1 Antibody has been validated for the following applications: Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Gel Supershift Assay, Block/Neutralize, PCR.
靶标 :
ABCA1
类别 :
一抗
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
Partial peptide sequence (within residues 1100-1300) of human ABCA1 [UniProt# O95477]. Actual immunogen sequence is proprietary information.
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
Human, Mouse, Rat, Porcine, Canine, Chicken, Chinese Hamster, Equine, Hamster, Mustelid, Primate, Rabbit
理论上的分子量 :
220 kDa
基因符号 :
ABCA1
catalog number base :
NB400-105
accessionNumbers :
O95477
应用 :
Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Gel Supershift Assay, Block/Neutralize, PCR
2020 Proposedprice USD :
349美元
别名 :
ABC-1, ABC1ATP-binding cassette transporter A1, ATP-binding cassette 1, ATP-binding cassette transporter 1, ATP-binding cassette, sub-family A (ABC1), member 1, CERP, Cholesterol efflux regulatory protein, EC 2.7.7.8, EC 2.8.1.8, EC 3.6.3, EC 3.6.3.41, FLJ14958, HDLDT1, membrane-bound, MGC164864, MGC165011, TGDATP-binding cassette sub-family A member 1
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。