产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
兔多克隆存活素抗体
目录 :
NB500-201
规格 :
0.1 ml (also 0.025 ml)
价格 :
349美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
几内亚, 仓鼠, 人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 143
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 1c
Schafer C, Göder A, Beyer M, Kiweler N, Mahendrarajah N, Rauch A, et al. Class I histone deacetylases regulate p53/NF-?B crosstalk in cancer cells. Cell Signal. 2017;29:218-225 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 3
Unruhe Knauf B, Knauer S. Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization. Methods Mol Biol. 2017;1510:47-59 pubmed
  • 免疫细胞化学; 人类; 图 3d
  • 免疫印迹; 人类; 图 4b
Kreger B, Johansen E, Cerione R, Antonyak M. The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance. Cancers (Basel). 2016;8: pubmed
  • 免疫印迹; 人类; 1:1000; 图 3
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed 出版商
  • 免疫印迹; 狗
Yamazaki H, Takagi S, Hosoya K, Okumura M. Influence of a survivin suppressor YM155 on the chemoresistance of canine histiocytic sarcoma cells. Vet J. 2015;205:375-80 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫组化; 人类
Locke F, Menges M, Veerapathran A, Coppola D, Gabrilovich D, Anasetti C. Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma. J Immunother Cancer. 2015;3:20 pubmed 出版商
  • 免疫印迹; 人类
Valenzuela M, Ferguson Bennit H, Gonda A, Diaz Osterman C, Hibma A, Khan S, et al. Exosomes Secreted from Human Cancer Cell Lines Contain Inhibitors of Apoptosis (IAP). Cancer Microenviron. 2015;8:65-73 pubmed 出版商
  • 免疫组化-石蜡切片; 狗
Bongiovanni L, D Andrea A, Porcellato I, Ciccarelli A, Malatesta D, Romanucci M, et al. Canine cutaneous melanocytic tumours: significance of β-catenin and survivin immunohistochemical expression. Vet Dermatol. 2015;26:270-e59 pubmed 出版商
  • 免疫组化; 人类; 1:500; 图 6c
Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed
  • 免疫组化-石蜡切片; 人类
Mehta A, Zhang L, Boufraqech M, Liu Chittenden Y, Zhang Y, Patel D, et al. Inhibition of Survivin with YM155 Induces Durable Tumor Response in Anaplastic Thyroid Cancer. Clin Cancer Res. 2015;21:4123-32 pubmed 出版商
  • 免疫印迹; 人类
Sulaiman M, Chu Z, Blanco V, Vallabhapurapu S, Franco R, Qi X. SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas. Mol Cancer. 2015;14:78 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Meidhof S, Brabletz S, Lehmann W, Preca B, Mock K, Ruh M, et al. ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med. 2015;7:831-47 pubmed 出版商
  • 免疫组化-石蜡切片; 狗
Yamazaki H, Takagi S, Hosoya K, Okumura M. Survivin suppressor (YM155) enhances chemotherapeutic efficacy against canine histiocytic sarcoma in murine transplantation models. Res Vet Sci. 2015;99:137-44 pubmed 出版商
  • 免疫细胞化学; 人类
Vogt N, Abramov D, Koch K, Masque Soler N, Szczepanowski M, Klapper W. No evidence of cell cycle dysregulation in mantle cell lymphoma in vivo. Leuk Lymphoma. 2015;56:2134-40 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Cornago M, Garcia Alberich C, Blasco Angulo N, Vall Llaura N, Nager M, Herreros J, et al. Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe. Cell Death Dis. 2014;5:e1435 pubmed 出版商
  • 免疫印迹; 人类
Grazia G, Vegetti C, Benigni F, Penna I, Perotti V, Tassi E, et al. Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma. Cell Death Dis. 2014;5:e1434 pubmed 出版商
  • 免疫印迹; 人类
Artesi M, Kroonen J, Bredel M, Nguyen Khac M, Deprez M, Schoysman L, et al. Connexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy. Neuro Oncol. 2015;17:392-406 pubmed 出版商
  • 免疫细胞化学; 人类
Althoff K, Lindner S, Odersky A, Mestdagh P, Beckers A, Karczewski S, et al. miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin. Int J Cancer. 2015;136:1308-20 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫印迹; 人类
Cao X, Lu H, Zhang L, Chen L, Gan M. MEKK3 and survivin expression in cervical cancer: association with clinicopathological factors and prognosis. Asian Pac J Cancer Prev. 2014;15:5271-6 pubmed
  • 免疫印迹; 人类
Ramírez Labrada A, López Royuela N, Jarauta V, Galán Malo P, Azaceta G, Palomera L, et al. Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis. Clin Transl Oncol. 2015;17:121-32 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫印迹; 人类
Khan S, Bennit H, Turay D, Perez M, Mirshahidi S, Yuan Y, et al. Early diagnostic value of survivin and its alternative splice variants in breast cancer. BMC Cancer. 2014;14:176 pubmed 出版商
  • 免疫印迹; 人类
Jin B, Ding K, Pan J. Ponatinib induces apoptosis in imatinib-resistant human mast cells by dephosphorylating mutant D816V KIT and silencing ?-catenin signaling. Mol Cancer Ther. 2014;13:1217-30 pubmed 出版商
  • 免疫印迹; 人类
Galloway N, Diaz Osterman C, Reiber K, Jutzy J, Li F, Sui G, et al. Yin Yang 1 regulates the transcriptional repression of Survivin. Biochem Biophys Res Commun. 2014;445:208-13 pubmed 出版商
  • 免疫印迹; 人类
Taniguchi F, Higaki H, Izawa M, Azuma Y, Hirakawa E, Deura I, et al. The cellular inhibitor of apoptosis protein-2 is a possible target of novel treatment for endometriosis. Am J Reprod Immunol. 2014;71:278-85 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Alaggio R, Turrini R, Boldrin D, Merlo A, Gambini C, Ferrari A, et al. Survivin expression and prognostic significance in pediatric malignant peripheral nerve sheath tumors (MPNST). PLoS ONE. 2013;8:e80456 pubmed 出版商
  • 免疫印迹; 狗
Yamazaki H, Takagi S, Hoshino Y, Hosoya K, Okumura M. Inhibition of survivin influences the biological activities of canine histiocytic sarcoma cell lines. PLoS ONE. 2013;8:e79810 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Zhang M, Zhang X, Zhao S, Wang Y, Di W, Zhao G, et al. Prognostic value of survivin and EGFR protein expression in triple-negative breast cancer (TNBC) patients. Target Oncol. 2014;9:349-57 pubmed
  • 免疫印迹; 人类
Li L, Tang W, Wu X, Karnak D, Meng X, Thompson R, et al. HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s. Clin Cancer Res. 2013;19:6703-15 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Matteucci C, Sorrentino R, Bellis L, Ettorre G, Svicher V, Santoro R, et al. Detection of high levels of Survivin-immunoglobulin M immune complex in sera from hepatitis C virus infected patients with cirrhosis. Hepatol Res. 2014;44:1008-18 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫印迹; 人类
Dallaglio K, Petrachi T, Marconi A, Truzzi F, Lotti R, Saltari A, et al. Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation. Int J Mol Sci. 2013;14:19540-55 pubmed 出版商
  • 免疫组化; 人类
Takagi K, Ishida T, Miki Y, Hirakawa H, Kakugawa Y, Amano G, et al. Intratumoral concentration of estrogens and clinicopathological changes in ductal carcinoma in situ following aromatase inhibitor letrozole treatment. Br J Cancer. 2013;109:100-8 pubmed 出版商
  • 免疫印迹; 人类
Kunze D, Erdmann K, Froehner M, Wirth M, Fuessel S. Enhanced inhibition of bladder cancer cell growth by simultaneous knockdown of antiapoptotic Bcl-xL and survivin in combination with chemotherapy. Int J Mol Sci. 2013;14:12297-312 pubmed 出版商
  • 免疫印迹; 人类
Tyagi A, Raina K, Gangar S, Kaur M, Agarwal R, Agarwal C. Differential effect of grape seed extract against human non-small-cell lung cancer cells: the role of reactive oxygen species and apoptosis induction. Nutr Cancer. 2013;65 Suppl 1:44-53 pubmed 出版商
  • 免疫印迹; 人类
Slagter Jäger J, Raney A, Lewis W, DeBenedette M, Nicolette C, Tcherepanova I. Evaluation of RNA Amplification Methods to Improve DC Immunotherapy Antigen Presentation and Immune Response. Mol Ther Nucleic Acids. 2013;2:e91 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Chiappara G, Gjomarkaj M, Virzì A, Sciarrino S, Ferraro M, Bruno A, et al. The role of p21 Waf1/Cip1 in large airway epithelium in smokers with and without COPD. Biochim Biophys Acta. 2013;1832:1473-81 pubmed 出版商
  • 免疫印迹; 人类
Honegger A, Leitz J, Bulkescher J, Hoppe Seyler K, Hoppe Seyler F. Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and the amounts of extracellular microvesicles released from HPV-positive cancer cells. Int J Cancer. 2013;133:1631-42 pubmed 出版商
  • 免疫印迹; 人类
Kan C, Petti C, Bracken L, Maritz M, Xu N, O Brien R, et al. Up-regulation of survivin during immortalization of human myofibroblasts is linked to repression of tumor suppressor p16(INK4a) protein and confers resistance to oxidative stress. J Biol Chem. 2013;288:12032-41 pubmed 出版商
  • 免疫印迹; 人类
Chiou S, Hoa N, Ge L, Jadus M. Nutrient availability alters the effect of autophagy on sulindac sulfide-induced colon cancer cell apoptosis. Gastroenterol Res Pract. 2012;2012:897678 pubmed 出版商
  • 免疫印迹; 小鼠
Wang Z, Zheng Y, Park H, Li J, Carr J, Chen Y, et al. Targeting FoxM1 effectively retards p53-null lymphoma and sarcoma. Mol Cancer Ther. 2013;12:759-67 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 仓鼠
Hori M, Miki T, Okamoto M, Yazama F, Konishi H, Kaneko H, et al. The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer. PLoS ONE. 2013;8:e55710 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Erba H, Sayar H, Juckett M, Lahn M, André V, Callies S, et al. Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML). Invest New Drugs. 2013;31:1023-34 pubmed 出版商
  • 免疫印迹; 人类
Goel H, Sayeed A, Breen M, Zarif M, Garlick D, Leav I, et al. ?1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1. J Cell Physiol. 2013;228:1601-9 pubmed 出版商
  • 免疫组化-石蜡切片; 狗
Bongiovanni L, D Andrea A, Romanucci M, Malatesta D, Candolini M, Salda L, et al. Epithelial-to-mesenchymal transition: immunohistochemical investigation of related molecules in canine cutaneous epithelial tumours. Vet Dermatol. 2013;24:195-203.e42-3 pubmed 出版商
  • 免疫沉淀; 人类
Tecleab A, Sebti S. Depletion of K-Ras promotes proteasome degradation of survivin. Cell Cycle. 2013;12:522-32 pubmed 出版商
  • 免疫组化; 人类
Knauer S, Unruhe B, Karczewski S, Hecht R, Fetz V, Bier C, et al. Functional characterization of novel mutations affecting survivin (BIRC5)-mediated therapy resistance in head and neck cancer patients. Hum Mutat. 2013;34:395-404 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Semrau R, Duerbaum H, Temming S, Huebbers C, Stenner M, Drebber U, et al. Prognostic impact of human papillomavirus status, survivin, and epidermal growth factor receptor expression on survival in patients treated with radiochemotherapy for very advanced nonresectable oropharyngeal cancer. Head Neck. 2013;35:1339-44 pubmed 出版商
  • 免疫组化; 人类
Min L, Ji Y, Bakiri L, Qiu Z, Cen J, Chen X, et al. Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin. Nat Cell Biol. 2012;14:1203-11 pubmed 出版商
  • 免疫印迹; 人类
Sun Y, Cheng M, Griffiths T, Mellon J, Kai B, Kriajevska M, et al. Inhibition of STAT signalling in bladder cancer by diindolylmethane: relevance to cell adhesion, migration and proliferation. Curr Cancer Drug Targets. 2013;13:57-68 pubmed
  • 免疫印迹; 人类
Kunze D, Kraemer K, Erdmann K, Froehner M, Wirth M, Fuessel S. Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells. Int J Oncol. 2012;41:1271-7 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫组化; 人类
de Souza H, West G, Rebert N, de la Motte C, Drazba J, Fiocchi C. Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease. Gastroenterology. 2012;143:1017-26.e9 pubmed 出版商
  • 免疫印迹; 人类
Jiang C, Yi X, Shen H, Li Y. Targeting X-linked inhibitor of apoptosis protein inhibits pancreatic cancer cell growth through p-Akt depletion. World J Gastroenterol. 2012;18:2956-65 pubmed 出版商
  • 免疫印迹; 人类
Okamoto W, Okamoto I, Arao T, Kuwata K, Hatashita E, Yamaguchi H, et al. Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification. Mol Cancer Ther. 2012;11:1557-64 pubmed 出版商
  • 免疫组化; 人类
Chao C, Silverberg M, Martinez Maza O, Chi M, Abrams D, Haque R, et al. Epstein-Barr virus infection and expression of B-cell oncogenic markers in HIV-related diffuse large B-cell Lymphoma. Clin Cancer Res. 2012;18:4702-12 pubmed
  • 免疫组化; 狗
Bongiovanni L, Mazzocchetti F, Malatesta D, Romanucci M, Ciccarelli A, Buracco P, et al. Immunohistochemical investigation of cell cycle and apoptosis regulators (survivin, ?-catenin, p53, caspase 3) in canine appendicular osteosarcoma. BMC Vet Res. 2012;8:78 pubmed 出版商
  • 免疫组化; 狗
Bongiovanni L, Suter M, Malatesta D, Ordinelli A, Ciccarelli A, Romanucci M, et al. Nuclear survivin expression as a potentially useful tool for the diagnosis of canine cutaneous sebaceous lesions. Vet Dermatol. 2012;23:394-e73 pubmed 出版商
  • 免疫印迹; 狗
Dhawan D, Ramos Vara J, Hahn N, Waddell J, Olbricht G, Zheng R, et al. DNMT1: an emerging target in the treatment of invasive urinary bladder cancer. Urol Oncol. 2013;31:1761-9 pubmed 出版商
  • 免疫组化; 人类
Ebata A, Suzuki T, Takagi K, Miki Y, Onodera Y, Nakamura Y, et al. Oestrogen-induced genes in ductal carcinoma in situ: their comparison with invasive ductal carcinoma. Endocr Relat Cancer. 2012;19:485-96 pubmed 出版商
  • 免疫印迹; 人类
Jacob N, Cooley J, Shirai K, Chakravarti A. Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation. Onco Targets Ther. 2012;5:7-20 pubmed 出版商
  • 免疫印迹; 人类
Francisco R, Pérez Perarnau A, Cortés C, Gil J, Tauler A, Ambrosio S. Histone deacetylase inhibition induces apoptosis and autophagy in human neuroblastoma cells. Cancer Lett. 2012;318:42-52 pubmed 出版商
  • 免疫组化; 人类
Yakirevich E, Samkari A, Holloway M, Lu S, Singh K, Yu J, et al. Total Survivin and acetylated Survivin correlate with distinct molecular subtypes of breast cancer. Hum Pathol. 2012;43:865-73 pubmed 出版商
  • 免疫组化; 人类
Diaz A, Valera A, Carrera C, Hakim S, Aguilera P, Garcia A, et al. Pigmented spindle cell nevus: clues for differentiating it from spindle cell malignant melanoma. A comprehensive survey including clinicopathologic, immunohistochemical, and FISH studies. Am J Surg Pathol. 2011;35:1733-42 pubmed 出版商
  • 免疫印迹; 人类
Saxena P, Trerotola M, Wang T, Li J, Sayeed A, VanOudenhove J, et al. PSA regulates androgen receptor expression in prostate cancer cells. Prostate. 2012;72:769-76 pubmed 出版商
  • 免疫细胞化学; 人类
Lechler P, Schaumburger J, Köck F, Balakrishnan S, Doukas S, Prantl L, et al. The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells. Calcif Tissue Int. 2011;89:211-20 pubmed 出版商
  • 免疫组化; 人类
Kim G, Lim S, Kim Y. Expression of HuR, COX-2, and survivin in lung cancers; cytoplasmic HuR stabilizes cyclooxygenase-2 in squamous cell carcinomas. Mod Pathol. 2011;24:1336-47 pubmed 出版商
  • 免疫印迹; 人类
Chen B, Yuping S, Ni J. Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1? induction. Mol Biol Rep. 2012;39:185-91 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 狗
Fossey S, Bear M, Lin J, Li C, Schwartz E, Li P, et al. The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines. BMC Cancer. 2011;11:112 pubmed 出版商
  • 免疫组化; 人类
  • 免疫印迹; 人类
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
Kim S, Bommareddy A, Singh S. Garlic constituent diallyl trisulfide suppresses x-linked inhibitor of apoptosis protein in prostate cancer cells in culture and in vivo. Cancer Prev Res (Phila). 2011;4:897-906 pubmed 出版商
  • 免疫组化-石蜡切片; 猪
  • 免疫组化-石蜡切片; 几内亚
Knauer S, Heinrich U, Bier C, Habtemichael N, Docter D, Helling K, et al. An otoprotective role for the apoptosis inhibitor protein survivin. Cell Death Dis. 2010;1:e51 pubmed 出版商
  • 免疫印迹; 人类
El Maarri O, Walier M, Behne F, van Üüm J, Singer H, Diaz Lacava A, et al. Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles. PLoS ONE. 2011;6:e16252 pubmed 出版商
  • 免疫印迹; 小鼠
Chun K, Langenbach R. The prostaglandin E2 receptor, EP2, regulates survivin expression via an EGFR/STAT3 pathway in UVB-exposed mouse skin. Mol Carcinog. 2011;50:439-48 pubmed 出版商
  • 免疫印迹; 小鼠
AbouAlaiwi W, Ratnam S, Booth R, Shah J, Nauli S. Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation. Hum Mol Genet. 2011;20:354-67 pubmed 出版商
  • 免疫印迹; 人类
Chock K, Allison J, Shimizu Y, ElShamy W. BRCA1-IRIS overexpression promotes cisplatin resistance in ovarian cancer cells. Cancer Res. 2010;70:8782-91 pubmed 出版商
  • 免疫印迹; 人类
Diaz R, González Sancho J, Soldevilla B, Silva J, Garcia J, Garcia V, et al. Differential regulation of TP73 isoforms by 1?,25-dihydroxyvitamin D3 and survivin in human colon and breast carcinomas. Genes Chromosomes Cancer. 2010;49:1135-42 pubmed 出版商
  • 免疫细胞化学; 人类
Wang F, Dai J, Daum J, Niedzialkowska E, Banerjee B, Stukenberg P, et al. Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. Science. 2010;330:231-5 pubmed 出版商
  • 免疫印迹; 人类
Ruckert F, Samm N, Lehner A, Saeger H, Grutzmann R, Pilarsky C. Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis. BMC Cancer. 2010;10:379 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Velmurugan B, Gangar S, Kaur M, Tyagi A, Deep G, Agarwal R. Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules. Pharm Res. 2010;27:2085-97 pubmed 出版商
  • 免疫组化; 小鼠
Lee S, Donehower L, Herron A, Moore D, Fu L. Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice. PLoS ONE. 2010;5:e10995 pubmed 出版商
  • 免疫组化; 人类
Kabbarah O, Nogueira C, Feng B, Nazarian R, Bosenberg M, Wu M, et al. Integrative genome comparison of primary and metastatic melanomas. PLoS ONE. 2010;5:e10770 pubmed 出版商
  • 免疫组化; 人类
Qi G, Kudo Y, Ando T, Tsunematsu T, Shimizu N, Siriwardena S, et al. Nuclear Survivin expression is correlated with malignant behaviors of head and neck cancer together with Aurora-B. Oral Oncol. 2010;46:263-70 pubmed 出版商
  • 免疫组化; 狗
Wimmershoff J, Polkinghorne A, Grest P, Schade B, Marchal T, Keller S, et al. Immunohistochemical detection of survivin in canine lymphoma. J Comp Pathol. 2010;142:311-22 pubmed 出版商
  • 免疫印迹; 小鼠
Weber A, Boger R, Vick B, Urbanik T, Haybaeck J, Zoller S, et al. Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice. Hepatology. 2010;51:1226-36 pubmed 出版商
  • 免疫组化; 人类
Svec J, Musílková J, Bryndová J, Jirasek T, Mandys V, Kment M, et al. Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia. Inflamm Bowel Dis. 2010;16:1127-37 pubmed 出版商
  • 免疫印迹; 人类
López Royuela N, Balsas P, Galán Malo P, Anel A, Marzo I, Naval J. Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells. Biochim Biophys Acta. 2010;1803:311-22 pubmed 出版商
  • 免疫印迹; 人类
Qi G, Tuncel H, Aoki E, Tanaka S, Oka S, Kaneko I, et al. Intracellular localization of survivin determines biological behavior in colorectal cancer. Oncol Rep. 2009;22:557-62 pubmed
  • 免疫细胞化学; 人类
Yuan J, Yang B, Zhong Z, Shats I, Milyavsky M, Rotter V, et al. Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase. Oncogene. 2009;28:2678-89 pubmed 出版商
  • 免疫组化; 人类
Augello C, Caruso L, Maggioni M, Donadon M, Montorsi M, Santambrogio R, et al. Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma. BMC Cancer. 2009;9:125 pubmed 出版商
  • 免疫印迹; 人类
Khan S, Aspe J, Asumen M, Almaguel F, Odumosu O, Acevedo Martinez S, et al. Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential. Br J Cancer. 2009;100:1073-86 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Maxia C, Perra M, Demurtas P, Minerba L, Murtas D, Piras F, et al. Relationship between the expression of cyclooxygenase-2 and survivin in primary pterygium. Mol Vis. 2009;15:458-63 pubmed
  • 免疫组化-石蜡切片; 大鼠
Adler M, Müller K, Rached E, Dekant W, Mally A. Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity. Carcinogenesis. 2009;30:711-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Fetz V, Bier C, Habtemichael N, Schuon R, Schweitzer A, Kunkel M, et al. Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivin. Int J Cancer. 2009;124:2033-41 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
  • 免疫印迹; 大鼠
Baba H, Wohlschlaeger J, Schmitz K, Nadalin S, Lang H, Benesch A, et al. Survivin is upregulated during liver regeneration in rats and humans and is associated with hepatocyte proliferation. Liver Int. 2009;29:585-92 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Appleyard M, O Neill M, Murray K, Paulin F, Bray S, Kernohan N, et al. Seliciclib (CYC202, R-roscovitine) enhances the antitumor effect of doxorubicin in vivo in a breast cancer xenograft model. Int J Cancer. 2009;124:465-72 pubmed 出版商
Drpic D, Almeida A, Aguiar P, Renda F, Damas J, Lewin H, et al. Chromosome Segregation Is Biased by Kinetochore Size. Curr Biol. 2018;28:1344-1356.e5 pubmed 出版商
Bradford E, Ryu S, Singh A, Lee G, Goretsky T, Sinh P, et al. Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease. J Immunol. 2017;199:1886-1897 pubmed 出版商
Redli P, Gasic I, Meraldi P, Nigg E, Santamaria A. The Ska complex promotes Aurora B activity to ensure chromosome biorientation. J Cell Biol. 2016;215:77-93 pubmed
Varughese R, Torp S. Survivin and gliomas: A literature review. Oncol Lett. 2016;12:1679-1686 pubmed
Qi G, Kudo Y, Tang B, Liu T, Jin S, Liu J, et al. PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer. Oncotarget. 2016;7:18812-24 pubmed 出版商
Werner T, Tamkan Ölcek Y, Dizdar L, Riemer J, Wolf A, Cupisti K, et al. Survivin and XIAP: two valuable biomarkers in medullary thyroid carcinoma. Br J Cancer. 2016;114:427-34 pubmed 出版商
Papini D, Langemeyer L, Abad M, Kerr A, Samejima I, Eyers P, et al. TD-60 links RalA GTPase function to the CPC in mitosis. Nat Commun. 2015;6:7678 pubmed 出版商
Lan L, Appelman C, Smith A, Yu J, Larsen S, Marquez R, et al. Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1. Mol Oncol. 2015;9:1406-20 pubmed 出版商
Yi X, Han T, Li Y, Long X, Li W. Simultaneous silencing of XIAP and survivin causes partial mesenchymal-epithelial transition of human pancreatic cancer cells via the PTEN/PI3K/Akt pathway. Mol Med Rep. 2015;12:601-8 pubmed 出版商
Fu D, Kato D, Watabe A, Endo Y, Kadosawa T. Prognostic utility of apoptosis index, Ki-67 and survivin expression in dogs with nasal carcinoma treated with orthovoltage radiation therapy. J Vet Med Sci. 2014;76:1505-12 pubmed
Lu H, Cao X, Chen Q, Chen L, Chen L, Gan M. The expression and role of MEKK3 in renal clear cell carcinoma. Anat Rec (Hoboken). 2015;298:727-34 pubmed 出版商
Kapinas K, Kim H, Mandeville M, Martin Buley L, Croce C, Lian J, et al. microRNA-mediated survivin control of pluripotency. J Cell Physiol. 2015;230:63-70 pubmed 出版商
Wang B, Zhao B, North P, Kong A, Huang J, Miao Q. Expression of NgBR is highly associated with estrogen receptor alpha and survivin in breast cancer. PLoS ONE. 2013;8:e78083 pubmed 出版商
Sayeed A, Fedele C, Trerotola M, Ganguly K, Languino L. IGF-IR promotes prostate cancer growth by stabilizing ?5?1 integrin protein levels. PLoS ONE. 2013;8:e76513 pubmed 出版商
Pannone G, Santoro A, Pasquali D, Zamparese R, Mattoni M, Russo G, et al. The role of survivin in thyroid tumors: differences of expression in well-differentiated, non-well-differentiated, and anaplastic thyroid cancers. Thyroid. 2014;24:511-9 pubmed 出版商
Dallaglio K, Marconi A, Truzzi F, Lotti R, Palazzo E, Petrachi T, et al. E-FABP induces differentiation in normal human keratinocytes and modulates the differentiation process in psoriatic keratinocytes in vitro. Exp Dermatol. 2013;22:255-61 pubmed 出版商
Cheng C, Chow A, Pang R, Fok E, Kwong Y, Tse E. PIN1 inhibits apoptosis in hepatocellular carcinoma through modulation of the antiapoptotic function of survivin. Am J Pathol. 2013;182:765-75 pubmed 出版商
Nakata Y, Yasuda T, Fukaya M, Yamamori S, Itakura M, Nihira T, et al. Accumulation of ?-synuclein triggered by presynaptic dysfunction. J Neurosci. 2012;32:17186-96 pubmed 出版商
Gnana Prakasam J, Veeranan Karmegam R, Coothankandaswamy V, Reddy S, Martin P, Thangaraju M, et al. Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2013;54:63-71 pubmed 出版商
Wang F, Ulyanova N, Daum J, Patnaik D, Kateneva A, Gorbsky G, et al. Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation. J Cell Biol. 2012;199:251-68 pubmed 出版商
Tuncel H, Shimamoto F, Kaneko Guangying Qi H, Aoki E, Jikihara H, Nakai S, et al. Nuclear Aurora B and cytoplasmic Survivin expression is involved in lymph node metastasis of colorectal cancer. Oncol Lett. 2012;3:1109-1114 pubmed
Stauber R, Knauer S, Habtemichael N, Bier C, Unruhe B, Weisheit S, et al. A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer. Oncotarget. 2012;3:31-43 pubmed
Felisiak Golabek A, Rembiszewska A, Rzepecka I, Szafron L, Madry R, Murawska M, et al. Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients. J Ovarian Res. 2011;4:20 pubmed 出版商
Kavitha C, Agarwal C, Agarwal R, Deep G. Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models. PLoS ONE. 2011;6:e22745 pubmed 出版商
Page B, Fletcher S, Yue P, Li Z, Zhang X, Sharmeen S, et al. Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain. Bioorg Med Chem Lett. 2011;21:5605-9 pubmed 出版商
Lechler P, Balakrishnan S, Schaumburger J, Grassel S, Baier C, Grifka J, et al. The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro. BMC Musculoskelet Disord. 2011;12:150 pubmed 出版商
El Ghamrasni S, Pamidi A, Halaby M, Bohgaki M, Cardoso R, Li L, et al. Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer. PLoS Genet. 2011;7:e1001385 pubmed 出版商
Peach G. Russia pledges $4 billion for Pharma-2020 plan. Nat Med. 2011;17:517 pubmed 出版商
Chiou S, Hoa N, Hodges A. Sulindac sulfide induces autophagic death in gastric epithelial cells via survivin down-regulation: a mechanism of NSAIDs-induced gastric injury. Biochem Pharmacol. 2011;81:1317-23 pubmed 出版商
Lechler P, Renkawitz T, Campean V, Balakrishnan S, Tingart M, Grifka J, et al. The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro. BMC Cancer. 2011;11:120 pubmed 出版商
Emmanuel C, Gava N, Kennedy C, Balleine R, Sharma R, Wain G, et al. Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis. PLoS ONE. 2011;6:e17617 pubmed 出版商
Finkelstein S, Iclozan C, Bui M, Cotter M, Ramakrishnan R, Ahmed J, et al. Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients. Int J Radiat Oncol Biol Phys. 2012;82:924-32 pubmed 出版商
Niibe Y, Watanabe J, Tsunoda S, Arai M, Arai T, Kawaguchi M, et al. Concomitant expression of HER2 and HIF-1alpha is a predictor of poor prognosis in uterine cervical carcinoma treated with concurrent chemoradiotherapy: prospective analysis (KGROG0501). Eur J Gynaecol Oncol. 2010;31:491-6 pubmed
Talbot D, Ranson M, Davies J, Lahn M, Callies S, André V, et al. Tumor survivin is downregulated by the antisense oligonucleotide LY2181308: a proof-of-concept, first-in-human dose study. Clin Cancer Res. 2010;16:6150-8 pubmed 出版商
Xia M, Knezevic D, Vassilev L. p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation. Oncogene. 2011;30:346-55 pubmed 出版商
Habtemichael N, W nsch D, Bier C, Tillmann S, Unruhe B, Frauenknecht K, et al. Cloning and functional characterization of the guinea pig apoptosis inhibitor protein Survivin. Gene. 2010;469:9-17 pubmed 出版商
Khan S, Jutzy J, Aspe J, McGregor D, Neidigh J, Wall N. Survivin is released from cancer cells via exosomes. Apoptosis. 2011;16:1-12 pubmed 出版商
Habtemichael N, Heinrich U, Knauer S, Schmidtmann I, Bier C, Docter D, et al. Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear. Mol Cell Neurosci. 2010;45:297-305 pubmed 出版商
Tango Y, Kano R, Maruyama H, Asano K, Tanaka S, Hasegawa A, et al. Detection of autoantibodies against survivin in sera from cancer dogs. J Vet Med Sci. 2010;72:917-20 pubmed
Allison S, Jiang M, Milner J. Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells. Aging (Albany NY). 2009;1:316-27 pubmed
Lou Y, Peng Q, Nolan B, Wagner G, LU Y. Oral administration of caffeine during voluntary exercise markedly decreases tissue fat and stimulates apoptosis and cyclin B1 in UVB-treated skin of hairless p53-knockout mice. Carcinogenesis. 2010;31:671-8 pubmed 出版商
Shariat S, Karakiewicz P, Godoy G, Karam J, Ashfaq R, Fradet Y, et al. Survivin as a prognostic marker for urothelial carcinoma of the bladder: a multicenter external validation study. Clin Cancer Res. 2009;15:7012-9 pubmed 出版商
Kim E, Teh S, Yang J, Chow M, Teh H. TNFR2-deficient memory CD8 T cells provide superior protection against tumor cell growth. J Immunol. 2009;183:6051-7 pubmed 出版商
Eberhard Y, McDermott S, Wang X, Gronda M, Venugopal A, Wood T, et al. Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells. Blood. 2009;114:3064-73 pubmed 出版商
Jia L, Soengas M, Sun Y. ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence. Cancer Res. 2009;69:4974-82 pubmed 出版商
Guha M, Plescia J, Leav I, Li J, Languino L, Altieri D. Endogenous tumor suppression mediated by PTEN involves survivin gene silencing. Cancer Res. 2009;69:4954-8 pubmed 出版商
Song K, Jung C, Park W, Park C. Expression of the antiapoptosis gene Survivin predicts poor prognosis of stage III gastric adenocarcinoma. Jpn J Clin Oncol. 2009;39:290-6 pubmed 出版商
Gould Rothberg B, Bracken M, Rimm D. Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis. J Natl Cancer Inst. 2009;101:452-74 pubmed 出版商
Lu J, Tan M, Huang W, Li P, Guo H, Tseng L, et al. Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance. Clin Cancer Res. 2009;15:1326-34 pubmed 出版商
Lee J, Palaia T, Ragolia L. Impaired insulin-mediated vasorelaxation in diabetic Goto-Kakizaki rats is caused by impaired Akt phosphorylation. Am J Physiol Cell Physiol. 2009;296:C327-38 pubmed 出版商
Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg E, Mayer T, et al. Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J Cell Biol. 2003;162:863-75 pubmed
产品信息
SKU号 :
NB500-201
产品名称 :
兔多克隆存活素抗体
规格 :
0.1 ml (also 0.025 ml)
描述 :
The Survivin Antibody from Novus Biologicals is a rabbit polyclonal antibody to Survivin. This antibody reacts with human, mouse, rat, canine, feline, guinea pig, hamster. The Survivin Antibody has been validated for the following applications: Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
靶标 :
存活素
类别 :
一抗
缓冲液 :
兔多克隆存活素抗体用品在PBS
克隆性 :
多克隆
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
Full length recombinant human Survivin [UniProt# O15392]
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种活性 :
人类, 小鼠, 大鼠, 狗, 猫, 豚鼠, 仓鼠
理论上的分子量 :
16.5 kDa
基因符号 :
BIRC5
AccessionNumbers :
O15392
应用 :
Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
价格 :
349美元
又名 :
API4 survivin variant 3 alpha, Apoptosis inhibitor 4 baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor survivin, baculoviral IAP repeat-containing 5, BIRC5, EPR-1, IAP4
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。