产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Clostridium Difficile Toxin A Antibody (PCG4.1) - BSA Free
目录 :
NB600-1066.1毫克
规格 :
0.1毫克
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
PCG4.1
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 20
参考文献
Wang S, Heuler J, Wickramage I, Sun X. Genomic and Phenotypic Characterization of the Nontoxigenic Clostridioides difficile Strain CCUG37785 and Demonstration of Its Therapeutic Potential for the Prevention of C. difficile Infection. Microbiol Spectr. 2022;10:e0178821 pubmed 出版商
Zhu D, Wang S, Sun X. FliW and CsrA Govern Flagellin (FliC) Synthesis and Play Pleiotropic Roles in Virulence and Physiology of Clostridioides difficile R20291. Front Microbiol. 2021;12:735616 pubmed 出版商
Zhu D, Patabendige H, Tomlinson B, Wang S, Hussain S, Flores D, et al. Cwl0971, a novel peptidoglycan hydrolase, plays pleiotropic roles in Clostridioides difficile R20291. Environ Microbiol. 2021;: pubmed 出版商
Oliveira P, Ribis J, Garrett E, Trzilova D, Kim A, Sekulovic O, et al. Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis. Nat Microbiol. 2020;5:166-180 pubmed 出版商
Edwards A, Anjuwon Foster B, McBride S. RstA Is a Major Regulator of Clostridioides difficile Toxin Production and Motility. MBio. 2019;10: pubmed 出版商
Daou N, Wang Y, Levdikov V, Nandakumar M, Livny J, Bouillaut L, et al. Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027. PLoS ONE. 2019;14:e0206896 pubmed 出版商
Woods E, Edwards A, Childress K, Jones J, McBride S. The C. difficile clnRAB operon initiates adaptations to the host environment in response to LL-37. PLoS Pathog. 2018;14:e1007153 pubmed 出版商
Anjuwon Foster B, Maldonado Vazquez N, Tamayo R. Characterization of Flagellum and Toxin Phase Variation in Clostridioides difficile Ribotype 012 Isolates. J Bacteriol. 2018;200: pubmed 出版商
Kroh H, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi M, et al. Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface. J Biol Chem. 2017;292:14401-14412 pubmed 出版商
Anjuwon Foster B, Tamayo R. A genetic switch controls the production of flagella and toxins in Clostridium difficile. PLoS Genet. 2017;13:e1006701 pubmed 出版商
Chandrasekaran R, Kenworthy A, Lacy D. Clostridium difficile Toxin A Undergoes Clathrin-Independent, PACSIN2-Dependent Endocytosis. PLoS Pathog. 2016;12:e1006070 pubmed 出版商
Childress K, Edwards A, Nawrocki K, Anderson S, Woods E, McBride S. The Phosphotransfer Protein CD1492 Represses Sporulation Initiation in Clostridium difficile. Infect Immun. 2016;84:3434-3444 pubmed
Edwards A, Tamayo R, McBride S. A novel regulator controls Clostridium difficile sporulation, motility and toxin production. Mol Microbiol. 2016;100:954-71 pubmed 出版商
Willing S, Richards E, Sempere L, Dale A, Cutting S, Fairweather N. Increased toxin expression in a Clostridium difficile mfd mutant. BMC Microbiol. 2015;15:280 pubmed 出版商
McKee R, Mangalea M, Purcell E, Borchardt E, Tamayo R. The second messenger cyclic Di-GMP regulates Clostridium difficile toxin production by controlling expression of sigD. J Bacteriol. 2013;195:5174-85 pubmed 出版商
Kolling G, Wu M, Warren C, Durmaz E, Klaenhammer T, Timko M, et al. Lactic acid production by Streptococcus thermophilus alters Clostridium difficile infection and in vitro Toxin A production. Gut Microbes. 2012;3:523-9 pubmed 出版商
Aubry A, Hussack G, Chen W, Kuolee R, Twine S, Fulton K, et al. Modulation of toxin production by the flagellar regulon in Clostridium difficile. Infect Immun. 2012;80:3521-32 pubmed 出版商
Vohra P, Poxton I. Comparison of toxin and spore production in clinically relevant strains of Clostridium difficile. Microbiology. 2011;157:1343-53 pubmed 出版商
Goulding D, Thompson H, Emerson J, Fairweather N, Dougan G, Douce G. Distinctive profiles of infection and pathology in hamsters infected with Clostridium difficile strains 630 and B1. Infect Immun. 2009;77:5478-85 pubmed 出版商
Dissanayake S, Olkhanud P, O Connell M, Carter A, French A, Camilli T, et al. Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer Res. 2008;68:10205-14 pubmed 出版商
图像
图像 1 :
Novus Biologicals NB600-1066-0.1mg 图像 1
Immunocytochemistry/Immunofluorescence: Clostridium Difficile Toxin A Antibody (PCG4.1) [NB600-1066] - TcdA colocalizes with PACSIN2 during entry in Caco-2 cells. Immunofluorescence assays were performed as described in Fig 1B. At indicated time points, cells were fixed, stained for PACSIN2 and analyzed by confocal microscopy. Merged images show PACSIN2 in red, toxin in green and colocalization in yellow. The images shown are representative of multiple fields imaged from three independent experiments. Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.ppat.1006070), licensed under a CC-BY licence.
产品信息
品牌 :
Novus
master code :
NB600-1066
SKU号 :
NB600-1066.1毫克
产品名称 :
Clostridium Difficile Toxin A Antibody (PCG4.1) - BSA Free
描述 :
The Clostridium Difficile Toxin A Antibody (PCG4.1) - BSA Free from Novus is a mouse monoclonal antibody to Clostridium Difficile Toxin A. This antibody reacts with bacteria. The Clostridium Difficile Toxin A Antibody (PCG4.1) - BSA Free has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry/Immunofluorescence.
靶标 :
Clostridium Difficile Toxin A
类别 :
一抗
单位尺寸 :
0.1毫克
缓冲液 :
10mM钠磷酸盐(pH值7.4)和0.15M氯化钠
克隆性 :
单克隆
克隆 :
PCG4.1
浓度 :
1.16毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Full length protein A (C. difficile).
抗体亚型 :
IgG2a Kappa
纯度 :
蛋白质A纯化
物种 :
细菌
特异性 :
C
images :
https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/Clostridium-Difficile-Toxin-A-Antibody-(PCG4.1)-Immunocytochemistry-Immunofluorescence-NB600-1066-img0007.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/Clostridium-Difficile-Toxin-A-Antibody-(PCG4.1)-Immunocytochemistry-Immunofluorescence-NB600-1066-img0007.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/Clostridium-Difficile-Toxin-A-Antibody-(PCG4.1)-Immunocytochemistry-Immunofluorescence-NB600-1066-img0007.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/Clostridium-Difficile-Toxin-A-Antibody-(PCG4.1)-Immunocytochemistry-Immunofluorescence-NB600-1066-img0001.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/Clostridium-Difficile-Toxin-A-Antibody-(PCG4.1)-Immunocytochemistry-Immunofluorescence-NB600-1066-img0001.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/Clostridium-Difficile-Toxin-A-Antibody-(PCG4.1)-Immunocytochemistry-Immunofluorescence-NB600-1066-img0001.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/Clostridium-Difficile-Toxin-A-Antibody-(PCG4.1)-Immunocytochemistry-Immunofluorescence-NB600-1066-img0006.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/Clostridium-Difficile-Toxin-A-Antibody-(PCG4.1)-Immunocytochemistry-Immunofluorescence-NB600-1066-img0006.jpg, https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/Clostridium-Difficile-Toxin-A-Antibody-(PCG4.1)-Immunocytochemistry-Immunofluorescence-NB600-1066-img0006.jpg
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学/免疫荧光
美元 :
279美元
别名 :
tcdA, toxA
储存 :
Store at 4C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。