产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
IL-6抗体
目录 :
NB600-1131
规格 :
0.2 ml (also 0.04 ml)
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 116
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:50; 图 2b
Novais E, Tran V, Johnston S, Darris K, Roupas A, Sessions G, et al. Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice. Nat Commun. 2021;12:5213 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:2000; 图 1d
  • 免疫组化-石蜡切片; 人类; 1:100; 图 s1c
  • 免疫印迹; 人类; 1:2000; 图 3c, 3d
Zhang K, Wang D, Cai H, Cao M, Zhang Y, Zhuang P, et al. IL‑6 plays a crucial role in epithelial‑mesenchymal transition and pro‑metastasis induced by sorafenib in liver cancer. Oncol Rep. 2021;45:1105-1117 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 4a
Gorth D, Shapiro I, Risbud M. Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration. Cell Death Dis. 2018;10:7 pubmed 出版商
Zhuang P, Wang D, Zhang K, Wang J, Shen J. Sorafenib promotes hepatocellular carcinoma invasion via interleukin-6/HIF-1α/PFKFB3. J Cancer. 2023;14:1859-1874 pubmed 出版商
Lee M, Ryu H, Hwang J, Kim J, Cho E, Choi J, et al. Sirt6 Activation Ameliorates Inflammatory Bone Loss in Ligature-Induced Periodontitis in Mice. Int J Mol Sci. 2023;24: pubmed 出版商
Zhang T, Zhang Y, Li S, Ge H, Song Q, Zhang Y, et al. Gentianella acuta-derived Gen-miR-1 suppresses myocardial fibrosis by targeting HAX1/HMG20A/Smads axis to attenuate inflammation in cardiac fibroblasts. Phytomedicine. 2023;118:154923 pubmed 出版商
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Sharma K, Kumar S, Prakash R, Khanka S, Mishra T, Rathur R, et al. Chebulinic acid alleviates LPS-induced inflammatory bone loss by targeting the crosstalk between reactive oxygen species/NFκB signaling in osteoblast cells. Free Radic Biol Med. 2023;194:99-113 pubmed 出版商
Zhao R, Lee D, Park C, Yang C, Kim H, Lee M, et al. Acupuncture Inhibits Morphine Induced-Immune Suppress via Antioxidant System. Evid Based Complement Alternat Med. 2022;2022:7971801 pubmed 出版商
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Kang E, Yim H, Nam Y, Jeong S, Kim J, Lee J, et al. Exposure to airborne particulate matter induces renal tubular cell injury in vitro: the role of vitamin D signaling and renin-angiotensin system. Heliyon. 2022;8:e10184 pubmed 出版商
Ottone O, Kim C, Collins J, Risbud M. The cGAS-STING Pathway Affects Vertebral Bone but Does Not Promote Intervertebral Disc Cell Senescence or Degeneration. Front Immunol. 2022;13:882407 pubmed 出版商
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Chen P, Wu H, Yao H, Zhang J, Fan W, Chen Z, et al. Multi-Omics Analysis Reveals the Systematic Relationship Between Oral Homeostasis and Chronic Sleep Deprivation in Rats. Front Immunol. 2022;13:847132 pubmed 出版商
Park J, Chi L, Kwon H, Lee J, Kim S, Hong S. Decaffeinated green tea extract as a nature-derived antibiotic alternative: An application in antibacterial nano-thin coating on medical implants. Food Chem. 2022;383:132399 pubmed 出版商
Gutziet O, Iluz R, Ben Asher H, Segal L, Ben Zvi D, Ginsberg Y, et al. Maternal N-Acetyl-Cysteine Prevents Neonatal Hypoxia-Induced Brain Injury in a Rat Model. Int J Mol Sci. 2021;22: pubmed 出版商
Ollewagen T, Powrie Y, Myburgh K, Smith C. Unresolved intramuscular inflammation, not diminished skeletal muscle regenerative capacity, is at the root of rheumatoid cachexia: insights from a rat CIA model. Physiol Rep. 2021;9:e15119 pubmed 出版商
Chow S, Cui C, Cheng K, Chim Y, Wang J, Wong C, et al. Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway. Int J Mol Sci. 2021;22: pubmed 出版商
Koga Y, Sotokawauchi A, Higashimoto Y, Nishino Y, Hashizume N, Kakuma T, et al. DNA-Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice. Oxid Med Cell Longev. 2021;2021:9932311 pubmed 出版商
Singh J, Thachil T, Eapen M, Lim A, Sufyan W, RAWSON R, et al. Immunohistochemical investigation of cytokine expression levels as biomarkers in transrectal ultrasound-guided needle biopsy specimens of prostate adenocarcinoma. Mol Clin Oncol. 2021;15:191 pubmed 出版商
Li Q, Qin L, Li J. IL-6 signaling pathway contributes to exercise pressor reflex in rats with femoral artery occlusion in association with Kv4 activity in muscle afferent nerves. Physiol Rep. 2021;9:e14935 pubmed 出版商
Betsou A, Lambropoulou M, Georgakopoulou A, Kostomitsopoulos N, Konstandi O, Anagnostopoulos K, et al. The hepatoprotective effect of silibinin after hepatic ischemia/reperfusion in a rat model is confirmed by immunohistochemistry and qRT-PCR. J Pharm Pharmacol. 2021;: pubmed 出版商
Subburaman M, Edderkaoui B. Evaluation of CCL21 role in post-knee injury inflammation and early cartilage degeneration. PLoS ONE. 2021;16:e0247913 pubmed 出版商
Kanno S, Hara A. The mRNA expression of Il6 and Pdcd1 are predictive and protective factors for doxorubicin‑induced cardiotoxicity. Mol Med Rep. 2021;23:1 pubmed 出版商
Lee G, Kim J, Lee J, Ko J, Lee E, Yoon J. Role of Proprotein Convertase Subtilisin/Kexin Type 9 in the Pathogenesis of Graves' Orbitopathy in Orbital Fibroblasts. Front Endocrinol (Lausanne). 2020;11:607144 pubmed 出版商
Shao H, Li Y, Pastar I, Xiao M, Prokupets R, Liu S, et al. Notch1 signaling determines the plasticity and function of fibroblasts in diabetic wounds. Life Sci Alliance. 2020;3: pubmed 出版商
Wu J, Dou Y, Ladiges W. Adverse Neurological Effects of Short-Term Sleep Deprivation in Aging Mice Are Prevented by SS31 Peptide. Clocks Sleep. 2020;2:325-333 pubmed 出版商
Balakrishnan I, Danis E, Pierce A, Madhavan K, Wang D, Dahl N, et al. Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG. Cell Rep. 2020;33:108286 pubmed 出版商
El Zayadi A, Mohamed S, Arafa M, Mohammed S, Zayed A, Abdelhafez M, et al. Anti-IL-6 receptor monoclonal antibody as a new treatment of endometriosis. Immunol Res. 2020;68:389-397 pubmed 出版商
Vaidya F, Sharma R, Shaikh S, Ray D, Aswal V, Pathak C. Pluronic micelles encapsulated curcumin manifests apoptotic cell death and inhibits pro-inflammatory cytokines in human breast adenocarcinoma cells. Cancer Rep (Hoboken). 2019;2:e1133 pubmed 出版商
Lee J, You J, Shin D, Roh J. Inhibition of Glutaredoxin 5 predisposes Cisplatin-resistant Head and Neck Cancer Cells to Ferroptosis. Theranostics. 2020;10:7775-7786 pubmed 出版商
Kim S, Cho J, Jue S, Park J, Kim J. Effect of Hyaluronic Acid Filler Injection on the Interdental Papilla in a Mouse Model of Open Gingival Embrasure. Int J Environ Res Public Health. 2020;17: pubmed 出版商
Liu J, Zhu Y, Guo Y, Lin L, Wang Z, Gu F, et al. Inhibition of GSK3β and RIP1K Attenuates Glial Scar Formation Induced by Ischemic Stroke via Reduction of Inflammatory Cytokine Production. Front Pharmacol. 2020;11:812 pubmed 出版商
Tekatas A, Tekatas D, Solmaz V, Karaca T, Pamuk O. Small fiber neuropathy and related factors in patients with systemic lupus erythematosus; the results of cutaneous silent period and skin biopsy. Adv Rheumatol. 2020;60:31 pubmed 出版商
Li S, Qian Z, Xu G, Zheng J, Wu Y. Hepatocyte growth factor protects PC12 cells against OGD/R-induced injury by reducing iron. Biosci Rep. 2020;40: pubmed 出版商
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Sheng Y, Chen Y, Qian Z, Zheng J, Liu Y. Cyclophosphamide induces a significant increase in iron content in the liver and spleen of mice. Hum Exp Toxicol. 2020;39:973-983 pubmed 出版商
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Neves J, Gomes A, Costa D, Barroso C, Vaulont S, Cordeiro da Silva A, et al. A role for hepcidin in the anemia caused by Trypanosoma brucei infection. Haematologica. 2020;: pubmed 出版商
Yasumura S, Naito Y, Okuno K, Sawada H, Asakura M, Masuyama T, et al. Effects of Heterozygous TfR1 (Transferrin Receptor 1) Deletion in Pathogenesis of Renal Fibrosis in Mice. Hypertension. 2020;75:413-421 pubmed 出版商
Chen Y, Qian Z, Sheng Y, Zheng J, Liu Y. Angiotensin II down-regulates transferrin receptor 1 and ferroportin 1 expression in Neuro-2a cells via activation of type-1 receptor. Neurosci Lett. 2020;716:134684 pubmed 出版商
Ashok A, Chaudhary S, McDonald D, Kritikos A, Bhargava D, Singh N. Local synthesis of hepcidin in the anterior segment of the eye: A novel observation with physiological and pathological implications. Exp Eye Res. 2020;190:107890 pubmed 出版商
Lv Y, Cang W, Li Q, Liao X, Zhan M, Deng H, et al. Erlotinib overcomes paclitaxel-resistant cancer stem cells by blocking the EGFR-CREB/GRβ-IL-6 axis in MUC1-positive cervical cancer. Oncogenesis. 2019;8:70 pubmed 出版商
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Thompson K, Wessling Resnick M. ZIP14 is degraded in response to manganese exposure. Biometals. 2019;32:829-843 pubmed 出版商
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Chen M, Reed R, Lane A. Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense. Cell Stem Cell. 2019;25:501-513.e5 pubmed 出版商
Pulos Holmes M, Srole D, Juarez M, Lee A, McSwiggen D, Ingolia N, et al. Repression of ferritin light chain translation by human eIF3. elife. 2019;8: pubmed 出版商
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Bach A, Conzen C, Schubert G, Bleilevens C, Lindauer U. Acute changes of pro-inflammatory markers and corticosterone in experimental subarachnoid haemorrhage: A prerequisite for severity assessment. PLoS ONE. 2019;14:e0220467 pubmed 出版商
Yan H, Hu Y, Akk A, Ye K, Bacon J, Pham C. Interleukin-12 and -23 blockade mitigates elastase-induced abdominal aortic aneurysm. Sci Rep. 2019;9:10447 pubmed 出版商
Poli M, Anower E Khuda F, Asperti M, Ruzzenenti P, Gryzik M, Denardo A, et al. Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice. J Biol Chem. 2019;294:13292-13303 pubmed 出版商
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Pandur E, Tamási K, Pap R, Varga E, Miseta A, Sipos K. Fractalkine Induces Hepcidin Expression of BV-2 Microglia and Causes Iron Accumulation in SH-SY5Y Cells. Cell Mol Neurobiol. 2019;: pubmed 出版商
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Yue S, Zheng X, Zheng Y. Cell-type-specific role of lamin-B1 in thymus development and its inflammation-driven reduction in thymus aging. Aging Cell. 2019;18:e12952 pubmed 出版商
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Geng S, Zhang Y, Lee C, Li L. Novel reprogramming of neutrophils modulates inflammation resolution during atherosclerosis. Sci Adv. 2019;5:eaav2309 pubmed 出版商
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Samba Mondonga M, Calvé A, Mallette F, Santos M. MyD88 Regulates the Expression of SMAD4 and the Iron Regulatory Hormone Hepcidin. Front Cell Dev Biol. 2018;6:105 pubmed 出版商
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Sajja R, Kaisar M, Vijay V, Desai V, Prasad S, Cucullo L. In Vitro Modulation of Redox and Metabolism Interplay at the Brain Vascular Endothelium: Genomic and Proteomic Profiles of Sulforaphane Activity. Sci Rep. 2018;8:12708 pubmed 出版商
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Zhang F, Hou H, Yin Z, Chang L, Li F, Chen Y, et al. Impairment of Hepcidin Upregulation by Lipopolysaccharide in the Interleukin-6 Knockout Mouse Brain. Front Mol Neurosci. 2017;10:367 pubmed 出版商
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Zhang W, Lv T, Huang J, Ou X. Type 4B hereditary hemochromatosis associated with a novel mutation in the SLC40A1 gene: A case report and a review of the literature. Medicine (Baltimore). 2017;96:e8064 pubmed 出版商
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Kaito T, Morimoto T, Mori Y, Kanayama S, Makino T, Takenaka S, et al. BMP-2/7 heterodimer strongly induces bone regeneration in the absence of increased soft tissue inflammation. Spine J. 2018;18:139-146 pubmed 出版商
Dietrich P, Johnson I, Alli S, Dragatsis I. Elimination of huntingtin in the adult mouse leads to progressive behavioral deficits, bilateral thalamic calcification, and altered brain iron homeostasis. PLoS Genet. 2017;13:e1006846 pubmed 出版商
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Cullis J, Siolas D, Avanzi A, Barui S, Maitra A, Bar Sagi D. Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer. Cancer Immunol Res. 2017;5:182-190 pubmed 出版商
Mertens C, Akam E, Rehwald C, Brüne B, Tomat E, Jung M. Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression. PLoS ONE. 2016;11:e0166164 pubmed 出版商
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Gasperini L, Meneghetti E, Legname G, Benetti F. In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution. Front Neurosci. 2016;10:437 pubmed
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产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB600-1131
SKU号 :
NB600-1131
产品名称 :
IL-6抗体
描述 :
The IL-6 Antibody from Novus is a rabbit polyclonal antibody to IL-6. This antibody reacts with human, mouse, rat, monkey. The IL-6 Antibody has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated.
靶标 :
IL-6
类别 :
一抗
单位尺寸 :
0.2 ml (also 0.04 ml)
缓冲液 :
0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2
克隆性 :
多克隆
共轭标签 :
未共轭
宿主 :
免疫原 :
This whole rabbit serum was prepared by repeated immunizations with recombinant human IL-6 produced in E.coli. (Uniprot: P05231)
抗体亚型 :
IgG
纯度 :
Unpurified
物种 :
Human, Mouse, Rat, Monkey
特异性 :
Anti-IL-6 antiserum detects recombinant and native IL-6 present in body fluids and cell supernatants in various assays (ie
基因符号 :
白细胞介素-6
accessionNumbers :
P05231, P05231, P05231, P05231, P05231
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡, 免疫组化冷冻, 基因敲减验证
美元 :
399美元
别名 :
B-cell differentiation factor, B-cell stimulatory factor 2, BSF2, BSF-2, CDF, CTL differentiation factor, HSF, hybridoma growth factor, IFNB2, IFN-beta-2, IL-6, Interferon beta-2, interleukin 6 (interferon, beta 2), interleukin BSF-2, interleukin-6
储存 :
Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。