产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
EpCAM/TROP1 Antibody (AUA1) - BSA Free
目录 :
NB600-1182
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AUA1
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 31
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanová T, et al. Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cell Mol Life Sci. 2022;79:445 pubmed 出版商
  • 免疫印迹; 人类
Aleksic T, Chitnis M, Perestenko O, Gao S, Thomas P, Turner G, et al. Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells. Cancer Res. 2010;70:6412-9 pubmed 出版商
  • 免疫细胞化学; 人类
Ntouroupi T, Ashraf S, McGregor S, Turney B, Seppo A, Kim Y, et al. Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope. Br J Cancer. 2008;99:789-95 pubmed 出版商
  • 流式细胞仪; 人类
Conaghan P, Ashraf S, Tytherleigh M, Wilding J, Tchilian E, Bicknell D, et al. Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen. Br J Cancer. 2008;98:1217-25 pubmed 出版商
  • 免疫印迹; 人类
Jordinson M, El Hariry I, Calnan D, Calam J, Pignatelli M. Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells. Gut. 1999;44:709-14 pubmed
  • 免疫细胞化学; 人类
  • 免疫组化; 人类
Anagnostaki E, Skarlos D, Tamvakis N, Psaropoulou P, Blana E, Bamias A, et al. Immunohistochemical and immunocytochemical study of bladder carcinomas using the epithelium-specific, tumour-associated monoclonal antibodies HMFG1 and AUA1. Br J Cancer Suppl. 1990;10:52-6 pubmed
  • 免疫细胞化学; 人类
Kocjan G, Sweeney E, Miller K, Bobrow L. AUA1: new immunocytochemical marker for detecting epithelial cells in body cavity fluids. J Clin Pathol. 1992;45:358-9 pubmed
Fan H, Atiya H, Wang Y, Pisanic T, Wang T, Shih I, et al. Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis. Cell Rep. 2020;33:108473 pubmed 出版商
de Vries M, Parma L, Peters H, Schepers A, Hamming J, Jukema J, et al. Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels. J Intern Med. 2019;285:59-74 pubmed 出版商
Chang Z, Wang Z, Shao D, Yue J, Xing H, Li L, et al. Shape Engineering Boosts Magnetic Mesoporous Silica Nanoparticle-Based Isolation and Detection of Circulating Tumor Cells. ACS Appl Mater Interfaces. 2018;10:10656-10663 pubmed 出版商
Albarenque S, Zwacka R, Mohr A. Both human and mouse mesenchymal stem cells promote breast cancer metastasis. Stem Cell Res. 2011;7:163-71 pubmed 出版商
Soares D, Battistella A, Rocca C, Matuo R, Henriques J, Larsen A, et al. Ataxia telangiectasia mutated- and Rad3-related kinase drives both the early and the late DNA-damage response to the monofunctional antitumour alkylator S23906. Biochem J. 2011;437:63-73 pubmed 出版商
Zheng L, Kanagaraj R, Mihaljevic B, Schwendener S, Sartori A, Gerrits B, et al. MRE11 complex links RECQ5 helicase to sites of DNA damage. Nucleic Acids Res. 2009;37:2645-57 pubmed 出版商
Helmink B, Bredemeyer A, Lee B, Huang C, Sharma G, Walker L, et al. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. J Exp Med. 2009;206:669-79 pubmed 出版商
Ottini L, Falchetti M, Saieva C, De Marco M, Masala G, Zanna I, et al. MRE11 expression is impaired in gastric cancer with microsatellite instability. Carcinogenesis. 2004;25:2337-43 pubmed
Giannini G, Rinaldi C, Ristori E, Ambrosini M, Cerignoli F, Viel A, et al. Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability. Oncogene. 2004;23:2640-7 pubmed
Uziel T, Lerenthal Y, Moyal L, Andegeko Y, Mittelman L, Shiloh Y. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 2003;22:5612-21 pubmed
Xu X, Stern D. NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors. FASEB J. 2003;17:1842-8 pubmed
Lee J, Xu B, Lee C, Ahn J, Song M, Lee H, et al. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage. Mol Cancer Res. 2003;1:674-81 pubmed
Celeste A, Fernandez Capetillo O, Kruhlak M, Pilch D, Staudt D, Lee A, et al. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol. 2003;5:675-9 pubmed
Stewart G, Wang B, Bignell C, Taylor A, Elledge S. MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature. 2003;421:961-6 pubmed
Lukas C, Falck J, Bartkova J, Bartek J, Lukas J. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat Cell Biol. 2003;5:255-60 pubmed
Xu X, Stern D. NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways. J Biol Chem. 2003;278:8795-803 pubmed
Nakanishi K, Taniguchi T, Ranganathan V, New H, Moreau L, Stotsky M, et al. Interaction of FANCD2 and NBS1 in the DNA damage response. Nat Cell Biol. 2002;4:913-20 pubmed
Stracker T, Carson C, Weitzman M. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature. 2002;418:348-52 pubmed
Limoli C, Giedzinski E, Bonner W, Cleaver J. UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization. Proc Natl Acad Sci U S A. 2002;99:233-8 pubmed
El Hariry I, Pignatelli M, Lemoine N. FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines. Br J Cancer. 2001;84:1656-63 pubmed
Harfst E, Cooper S, Neubauer S, Distel L, Grawunder U. Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome. Mol Immunol. 2000;37:915-29 pubmed
Lombard D, Guarente L. Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres. Cancer Res. 2000;60:2331-4 pubmed
Gatei M, Young D, Cerosaletti K, Desai Mehta A, Spring K, Kozlov S, et al. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nat Genet. 2000;25:115-9 pubmed
Wang Y, Cortez D, Yazdi P, Neff N, Elledge S, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 2000;14:927-39 pubmed
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB600-1182
SKU号 :
NB600-1182
产品名称 :
EpCAM/TROP1 Antibody (AUA1) - BSA Free
描述 :
The EpCAM/TROP1 Antibody (AUA1) - BSA Free from Novus is a mouse monoclonal antibody to EpCAM/TROP1. This antibody reacts with human. The EpCAM/TROP1 Antibody (AUA1) - BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, CyTOF-ready.
靶标 :
EpCAM/TROP1
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
AUA1
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
LoVo cell line preparation (Human).
抗体亚型 :
IgG1
纯度 :
蛋白质G纯化
物种 :
人类
理论上的分子量 :
35 kDa
基因符号 :
EPCAM
应用 :
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, CyTOF-ready
美元 :
399美元
别名 :
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。