产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
GADD153/CHOP抗体(9C8)
目录 :
NB600-1335
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF488
克隆名称 :
9C8
反应物种 :
primate, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 41
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:100; 图 4j
Herranen A, Ikäheimo K, Lankinen T, Pakarinen E, Fritzsch B, Saarma M, et al. Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss. Cell Death Dis. 2020;11:100 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 5c
Pommier A, Anaparthy N, Memos N, Kelley Z, Gouronnec A, Yan R, et al. Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases. Science. 2018;360: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1F
Zismanov V, Chichkov V, Colangelo V, Jamet S, Wang S, Syme A, et al. Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal. Cell Stem Cell. 2016;18:79-90 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Lee Y, Hah Y, Ha Y, Kang Y, Kang K, Hwang J, et al. The autophagy-related marker LC3 can predict prognosis in human hepatocellular carcinoma. PLoS ONE. 2013;8:e81540 pubmed 出版商
  • 免疫印迹; 人类
Lin C, Lee C, Shih Y, Lin C, Wang S, Chen T, et al. Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells. PLoS ONE. 2012;7:e38706 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫细胞化学; primate
Wang X, Harding H, Zhang Y, Jolicoeur E, Kuroda M, Ron D. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J. 1998;17:5708-17 pubmed
  • 免疫沉淀; 小鼠
  • 免疫印迹; 小鼠
Wang X, Kuroda M, Sok J, Batchvarova N, Kimmel R, Chung P, et al. Identification of novel stress-induced genes downstream of chop. EMBO J. 1998;17:3619-30 pubmed
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
Zinszner H, Sok J, Immanuel D, Yin Y, Ron D. TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling. J Cell Sci. 1997;110 ( Pt 15):1741-50 pubmed
  • 免疫沉淀; 小鼠
  • 免疫印迹; 小鼠
Saisanit S, Sun X. Regulation of the pro-B-cell-specific enhancer of the Id1 gene involves the C/EBP family of proteins. Mol Cell Biol. 1997;17:844-50 pubmed
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
Wang X, Lawson B, Brewer J, Zinszner H, Sanjay A, Mi L, et al. Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol Cell Biol. 1996;16:4273-80 pubmed
  • 免疫沉淀; 小鼠
  • 免疫印迹; 小鼠
Wang X, Ron D. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science. 1996;272:1347-9 pubmed
  • 免疫印迹; 小鼠
Batchvarova N, Wang X, Ron D. Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). EMBO J. 1995;14:4654-61 pubmed
Mekhael O, Revill S, Hayat A, Cass S, MACDONALD K, Vierhout M, et al. Myeloid-specific deletion of activating transcription factor 6 alpha increases CD11b+ macrophage subpopulations and aggravates lung fibrosis. Immunol Cell Biol. 2023;101:412-427 pubmed 出版商
Chandrasekaran R, Bruno S, Mark Z, Walzer J, Caffry S, Gold C, et al. Mitoquinone mesylate attenuates pathological features of lean and obese allergic asthma in mice. Am J Physiol Lung Cell Mol Physiol. 2023;324:L141-L153 pubmed 出版商
Dolatabadi S, Jonasson E, Andersson L, Luna Santamar xed a M, Lind xe9 n M, xd6 sterlund T, et al. FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma. Front Oncol. 2022;12:816894 pubmed 出版商
Wu L, He S, Ye W, Shen J, Zhao K, Zhang Y, et al. Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress. Cell Prolif. 2021;54:e13133 pubmed 出版商
Zhao S, Chen W, Li W, Yu W, Li S, Rao T, et al. LncRNA TUG1 attenuates ischaemia-reperfusion-induced apoptosis of renal tubular epithelial cells by sponging miR-144-3p via targeting Nrf2. J Cell Mol Med. 2021;25:9767-9783 pubmed 出版商
Fresia D, Cannizzaro E, Borgo A, Roduit R. GSH-Independent Induction of ER Stress during Hypoglycaemia in the Retinal Cells of Mice. J Clin Med. 2021;10: pubmed 出版商
Zhang X, Hu X, Wang H, Kan W, Xu L, Wang Z, et al. Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma. Acta Pharmacol Sin. 2020;: pubmed 出版商
Chen L, Xia Y, Shen S, Tang J, Chen J, Qian K, et al. Syntaxin 17 inhibits ischemic neuronal injury by resuming autophagy flux and ameliorating endoplasmic reticulum stress. Free Radic Biol Med. 2020;160:319-333 pubmed 出版商
Timberlake Ii M, Roy B, Dwivedi Y. A Novel Animal Model for Studying Depression Featuring the Induction of the Unfolded Protein Response in Hippocampus. Mol Neurobiol. 2019;: pubmed 出版商
Kim J, Kim B, Kim D, Jeong Y, Jeong S, Na Y, et al. Cannabidiol Enhances the Therapeutic Effects of TRAIL by Upregulating DR5 in Colorectal Cancer. Cancers (Basel). 2019;11: pubmed 出版商
Nakada E, Bhakta N, Korwin Mihavics B, Kumar A, Chamberlain N, Bruno S, et al. Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers. JCI Insight. 2019;4: pubmed 出版商
Lindén M, Thomsen C, Grundevik P, Jonasson E, Andersson D, Runnberg R, et al. FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex. EMBO Rep. 2019;20: pubmed 出版商
Nakandakari S, Muñoz V, Kuga G, Gaspar R, Sant Ana M, Pavan I, et al. Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice. Brain Behav Immun. 2019;79:284-293 pubmed 出版商
Delbrel E, Soumare A, Naguez A, Label R, Bernard O, Bruhat A, et al. HIF-1α triggers ER stress and CHOP-mediated apoptosis in alveolar epithelial cells, a key event in pulmonary fibrosis. Sci Rep. 2018;8:17939 pubmed 出版商
Siegert A, Garcia Díaz Barriga G, Esteve Codina A, Navas Madroñal M, Gorbenko del Blanco D, Alberch J, et al. A FBN1 3'UTR mutation variant is associated with endoplasmic reticulum stress in aortic aneurysm in Marfan syndrome. Biochim Biophys Acta Mol Basis Dis. 2019;1865:107-114 pubmed 出版商
Maciel M, Hernández Barrientos D, Herrera I, Selman M, Pardo A, Cabrera S. Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury. Aging (Albany NY). 2018;10:2098-2112 pubmed 出版商
Cueno M, Ochiai K. Gingival Periodontal Disease (PD) Level-Butyric Acid Affects the Systemic Blood and Brain Organ: Insights Into the Systemic Inflammation of Periodontal Disease. Front Immunol. 2018;9:1158 pubmed 出版商
Guo J, Cui Y, Liu Q, Yang Y, Li Y, Weng L, et al. Piperine ameliorates SCA17 neuropathology by reducing ER stress. Mol Neurodegener. 2018;13:4 pubmed 出版商
Verma S, Pillay P, Naicker T, Moodley J, Mackraj I. Placental hypoxia inducible factor -1? & CHOP immuno-histochemical expression relative to maternal circulatory syncytiotrophoblast micro-vesicles in preeclamptic and normotensive pregnancies. Eur J Obstet Gynecol Reprod Biol. 2018;220:18-24 pubmed 出版商
Jain A, ZODE G, Kasetti R, Ran F, Yan W, Sharma T, et al. CRISPR-Cas9-based treatment of myocilin-associated glaucoma. Proc Natl Acad Sci U S A. 2017;114:11199-11204 pubmed 出版商
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z. Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice. Sci Rep. 2017;7:8976 pubmed 出版商
Kilaparty S, Agarwal R, Singh P, Kannan K, Ali N. Endoplasmic reticulum stress-induced apoptosis accompanies enhanced expression of multiple inositol polyphosphate phosphatase 1 (Minpp1): a possible role for Minpp1 in cellular stress response. Cell Stress Chaperones. 2016;21:593-608 pubmed 出版商
Ying R, Wang X, Yang Y, Gu Z, Mai J, Qiu Q, et al. Hydrogen sulfide suppresses endoplasmic reticulum stress-induced endothelial-to-mesenchymal transition through Src pathway. Life Sci. 2016;144:208-17 pubmed 出版商
Djelti F, Braudeau J, Hudry E, Dhenain M, Varin J, Bièche I, et al. CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease. Brain. 2015;138:2383-98 pubmed 出版商
Sun Q, Zhong W, Zhang W, Li Q, Sun X, Tan X, et al. Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways. Am J Physiol Gastrointest Liver Physiol. 2015;308:G757-66 pubmed 出版商
Su C. Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl‑1 and Bcl‑xL and increasing Bax and CHOP protein expression. Int J Mol Med. 2014;34:1661-8 pubmed 出版商
Hull R, Zraika S, Udayasankar J, Aston Mourney K, Subramanian S, Kahn S. Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress. Diabetologia. 2009;52:1102-11 pubmed 出版商
Kuroda M, Wang X, Sok J, Yin Y, Chung P, Giannotti J, et al. Induction of a secreted protein by the myxoid liposarcoma oncogene. Proc Natl Acad Sci U S A. 1999;96:5025-30 pubmed
Sok J, Wang X, Batchvarova N, Kuroda M, Harding H, Ron D. CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI. Mol Cell Biol. 1999;19:495-504 pubmed
产品信息
品牌 :
Novus
MasterCode :
NB600-1335
SKU号 :
NB600-1335
产品名称 :
GADD153/CHOP抗体(9C8)
描述 :
The GADD153/CHOP Antibody (9C8) from NB600-1335 is a nb600-1335 antibody to . This antibody reacts with apoptosis, cell cycle and replication, dna repair, hypoxia, lipid and metabolism, neuroscience, unfolded protein response. The GADD153/CHOP Antibody (9C8) has been validated for the following applications: P35638, P35639.
靶标 :
GADD153/CHOP
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
三羟甲基氨基甲烷甘氨酸, 0.15 M氯化钠
克隆性 :
单克隆
克隆 :
9C8
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Full length mouse CHOP/GADD153 [Swiss-Prot# P35639]
抗体亚型 :
IgG2b Kappa
纯度 :
蛋白质A纯化
物种 :
人类, 小鼠, 大鼠, 灵长类动物
理论上的分子量 :
19 kDa
基因符号 :
DDIT3
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Flow-Cytometry-NB600-1335-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Flow-Cytometry-NB600-1335-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Flow-Cytometry-NB600-1335-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Western-Blot-NB600-1335-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Immunohistochemistry-Paraffin-NB600-1335-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Simple-Western-NB600-1335-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Simple-Western-NB600-1335-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/GADD153-CHOP-Antibody-(9C8)-Simple-Western-NB600-1335-img0007.jpg
accessionNumbers :
P35638, P35639
应用 :
Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Gel Super Shift Assays, Chromatin Immunoprecipitation (ChIP), Knockdown Validated
美元 :
399美元
别名 :
C/EBP-homologous protein, C/EBP-homologous protein 10, CCAAT/enhancer-binding protein homologous protein, CHOP-10, CHOP10 CEBPZ, CHOPC/EBP zeta, DDIT-3, DNA damage-inducible transcript 3 protein, DNA-damage-inducible transcript 3, GADD153, Growth arrest and DNA damage-inducible protein GADD153
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。