产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
PKC甲抗体(MC5)
目录 :
NB600-201
规格 :
0.1 ml (also 0.025 ml)
价格 :
299美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MC5
反应物种 :
人类, 小鼠, 大鼠, 犬, 鸡, 牛, 斑马鱼
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 放射免疫分析法, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 36
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:1000
Bayley P, Morgans C. Rod bipolar cells and horizontal cells form displaced synaptic contacts with rods in the outer nuclear layer of the nob2 retina. J Comp Neurol. 2007;500:286-98 pubmed
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Ng T, Parsons M, Hughes W, Monypenny J, Zicha D, Gautreau A, et al. Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility. EMBO J. 2001;20:2723-41 pubmed
  • 免疫印迹; 大鼠
Cesare P, Dekker L, Sardini A, Parker P, McNaughton P. Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat. Neuron. 1999;23:617-24 pubmed
  • 免疫印迹; 大鼠
Ricciarelli R, Tasinato A, Clement S, Ozer N, Boscoboinik D, Azzi A. alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state. Biochem J. 1998;334 ( Pt 1):243-9 pubmed
  • 免疫印迹; 大鼠
Gatti A, Robinson P. Okadaic acid interferes with phorbol-ester-mediated down-regulation of protein kinase C-alpha, C-delta and C-epsilon. Eur J Biochem. 1997;249:92-7 pubmed
  • 免疫印迹; 大鼠
Clement S, Tasinato A, Boscoboinik D, Azzi A. The effect of alpha-tocopherol on the synthesis, phosphorylation and activity of protein kinase C in smooth muscle cells after phorbol 12-myristate 13-acetate down-regulation. Eur J Biochem. 1997;246:745-9 pubmed
  • 免疫印迹; 大鼠
Gatti A, Robinson P. Unique phosphorylation of protein kinase C-alpha in PC12 cells induces resistance to translocation and down-regulation. J Biol Chem. 1996;271:31718-22 pubmed
  • 免疫细胞化学; 小鼠
  • 免疫细胞化学; 人类
Wyss Coray T, Masliah E, Toggas S, Rockenstein E, Brooker M, Lee H, et al. Dysregulation of signal transduction pathways as a potential mechanism of nervous system alterations in HIV-1 gp120 transgenic mice and humans with HIV-1 encephalitis. J Clin Invest. 1996;97:789-98 pubmed
  • 免疫印迹; 大鼠
Escriba P, Sastre M, García Sevilla J. Disruption of cellular signaling pathways by daunomycin through destabilization of nonlamellar membrane structures. Proc Natl Acad Sci U S A. 1995;92:7595-9 pubmed
  • 免疫印迹; 人类
Lacal J, Cuadrado A, Jones J, Trotta R, Burstein D, Thomson T, et al. Regulation of protein kinase C activity in neuronal differentiation induced by the N-ras oncogene in PC-12 cells. Mol Cell Biol. 1990;10:2983-90 pubmed
Hayward B, Steinbach P, Usdin K. A point mutation in the nuclease domain of MLH3 eliminates repeat expansions in a mouse stem cell model of the Fragile X-related disorders. Nucleic Acids Res. 2020;: pubmed 出版商
Sun H, Yang X, Liang L, Zhang M, Li Y, Chen J, et al. Metabolic switch and epithelial-mesenchymal transition cooperate to regulate pluripotency. EMBO J. 2020;39:e102961 pubmed 出版商
Liu Z, Yao M, Yao H, Hu G, Qin B. Generation of Rybp homozygous knockout murine ES cell line GIBHe001-A-1 by using CRISPR/Cas9 technology. Stem Cell Res. 2019;41:101638 pubmed 出版商
Malik V, Glaser L, Zimmer D, Velychko S, Weng M, Holzner M, et al. Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2. Nat Commun. 2019;10:3477 pubmed 出版商
Grillo S, McDevitt D, Voas M, Khan A, Grillo M, Stella S. Adenosine receptor expression in the adult zebrafish retina. Purinergic Signal. 2019;15:327-342 pubmed 出版商
Lin Y, Liang W, Chen C, Tsang H, Chiou J, Liu X, et al. Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells. Phytomedicine. 2019;58:152893 pubmed 出版商
Castelli A, Susani L, Menale C, Muggeo S, Caldana E, Strina D, et al. Chromosome Transplantation: Correction of the Chronic Granulomatous Disease Defect in Mouse Induced Pluripotent Stem Cells. Stem Cells. 2019;37:876-887 pubmed 出版商
Glennon E, Austin L, Arang N, Kain H, Mast F, Vijayan K, et al. Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage Infection. Cell Rep. 2019;26:3391-3399.e4 pubmed 出版商
Kodama Y, Harinath D, Mihara Tomiyama N, Tominaga N, Ide Y, Nakahara T, et al. Hmga2 regulation of tooth formation and association with Sox2 and Nanog expression. Biochem Biophys Res Commun. 2019;509:1008-1014 pubmed 出版商
Ahmed M, El Sayed A, Chen H, Zhao R, Jin K, Zuo Q, et al. Direct conversion of mouse embryonic fibroblast to osteoblast cells using hLMP-3 with Yamanaka factors. Int J Biochem Cell Biol. 2019;106:84-95 pubmed 出版商
Hellmer C, Clemons M, Nawy S, Ichinose T. A group I metabotropic glutamate receptor controls synaptic gain between rods and rod bipolar cells in the mouse retina. Physiol Rep. 2018;6:e13885 pubmed 出版商
Liu C, Cai Z, Jin G, Peng D, Pan B, Zhang X, et al. Abnormal gametogenesis induced by p53 deficiency promotes tumor progression and drug resistance. Cell Discov. 2018;4:54 pubmed 出版商
Veerapandian V, Ackermann J, Srivastava Y, Malik V, Weng M, Yang X, et al. Directed Evolution of Reprogramming Factors by Cell Selection and Sequencing. Stem Cell Reports. 2018;11:593-606 pubmed 出版商
Lee J, Kim M, Park S, Jang Y. Tousled-like kinase 1 is a negative regulator of core transcription factors in murine embryonic stem cells. Sci Rep. 2018;8:334 pubmed 出版商
Zhang N, Lyu Y, Pan X, Xu L, Xuan A, He X, et al. miR‑146b‑5p promotes the neural conversion of pluripotent stem cells by targeting Smad4. Int J Mol Med. 2017;40:814-824 pubmed 出版商
Xie J, Huo S, Li Y, Dai J, Xu H, Yin Z. Olfactory Ensheathing Cells Inhibit Gliosis in Retinal Degeneration by Downregulation of the Müller Cell Notch Signaling Pathway. Cell Transplant. 2017;26:967-982 pubmed 出版商
Pandolfini L, Luzi E, Bressan D, Ucciferri N, Bertacchi M, Brandi R, et al. RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells. Genome Biol. 2016;17:94 pubmed 出版商
Guimarães Souza E, Perche O, Morgans C, Duvoisin R, Calaza K. Fragile X Mental Retardation Protein expression in the retina is regulated by light. Exp Eye Res. 2016;146:72-82 pubmed 出版商
Paulis M, Castelli A, Susani L, Lizier M, Lagutina I, Focarelli M, et al. Chromosome transplantation as a novel approach for correcting complex genomic disorders. Oncotarget. 2015;6:35218-30 pubmed 出版商
Neri T, Muggeo S, Paulis M, Caldana M, Crisafulli L, Strina D, et al. Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts. Stem Cell Reports. 2015;5:558-68 pubmed 出版商
Kim J, Liu Y, Qiu M, Xu Y. Pluripotency factor Nanog is tumorigenic by deregulating DNA damage response in somatic cells. Oncogene. 2016;35:1334-40 pubmed 出版商
Palla A, Piazzolla D, Alcazar N, Cañamero M, Graña O, Gómez López G, et al. The pluripotency factor NANOG promotes the formation of squamous cell carcinomas. Sci Rep. 2015;5:10205 pubmed 出版商
Bertacchi M, Pandolfini L, D Onofrio M, Brandi R, Cremisi F. The double inhibition of endogenously produced BMP and Wnt factors synergistically triggers dorsal telencephalic differentiation of mouse ES cells. Dev Neurobiol. 2015;75:66-79 pubmed 出版商
Carelli S, Messaggio F, Canazza A, Hebda D, Caremoli F, Latorre E, et al. Characteristics and Properties of Mesenchymal Stem Cells Derived From Microfragmented Adipose Tissue. Cell Transplant. 2015;24:1233-52 pubmed 出版商
Zimov S, Yazulla S. Novel processes invaginate the pre-synaptic terminal of retinal bipolar cells. Cell Tissue Res. 2008;333:1-16 pubmed 出版商
Quraishi S, Gayet J, Morgans C, Duvoisin R. Distribution of group-III metabotropic glutamate receptors in the retina. J Comp Neurol. 2007;501:931-43 pubmed
图像
图像 1 :
Novus Biologicals NB600-201 图像 1
Immunocytochemistry/Immunofluorescence: PKC alpha Antibody (MC5) [NB600-201] - PKC alpha (MC5) antibody was tested in SH-SY5Y cells with Dylight 488 (green). Nuclei and beta-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).
产品信息
品牌 :
Novus
master code :
NB600-201
SKU号 :
NB600-201
产品名称 :
PKC甲抗体(MC5)
描述 :
The PKC alpha Antibody (MC5) from Novus is a mouse monoclonal antibody to PKC alpha. This antibody reacts with human, mouse, rat, porcine, bovine, canine, chicken, fish, rabbit, sheep, zebrafish. The PKC alpha Antibody (MC5) has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Radioimmunoassay.
靶标 :
PKC甲
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
三羟甲基氨基甲烷甘氨酸和0.15M氯化钠
克隆性 :
单克隆
克隆 :
MC5
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
纯化牛大脑蛋白激酶C
抗体亚型 :
IgG2a
纯度 :
蛋白质A纯化
物种 :
人类, 小鼠, 大鼠, 猪, 牛, 狗, 鸡, 鱼类, 兔, 羊, 斑马鱼
特异性 :
This antibody is capable of detecting PKC beta as well.
基因符号 :
PRKCA
catalog number base :
NB600-201
accessionNumbers :
P17252, P04409
应用 :
免疫印迹, 流式细胞仪, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡, 免疫组化冷冻, 放射免疫分析法
美元 :
299美元
别名 :
AAG6, aging-associated gene 6, EC 2.7.11, EC 2.7.11.13, MGC129901, PKC-A, PKC-alpha, PKCAMGC129900, PRKACA, protein kinase C alpha type, protein kinase C, alpha
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。