产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
c Myc抗体(9E10)
目录 :
NB600-302
规格 :
0.1 ml (also 0.025 ml)
价格 :
299美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
9.00E+10
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Iampietro M, Morissette G, Gravel A, Flamand L. Inhibition of interleukin-2 gene expression by human herpesvirus 6B U54 tegument protein. J Virol. 2014;88:12452-63 pubmed 出版商
  • 免疫沉淀; 小鼠
Santini E, Feyder M, Gangarossa G, Bateup H, Greengard P, Fisone G. Dopamine- and cAMP-regulated phosphoprotein of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin complex 1 (mTORC1) signaling in experimental parkinsonism. J Biol Chem. 2012;287:27806-12 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Wang H, Shao Z, Shi L, Hwang P, Truong L, Berns M, et al. CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks. J Biol Chem. 2012;287:21471-80 pubmed 出版商
  • 免疫印迹; 人类
Zhao Y, Wang Y, Hu J, Zhang X, Zhang Y. CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates ?-cleavage of ?-amyloid precursor protein (APP) through interacting with ?-site APP cleaving protein 1 (BACE1). J Biol Chem. 2012;287:11141-50 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Hubbi M, Luo W, Baek J, Semenza G. MCM proteins are negative regulators of hypoxia-inducible factor 1. Mol Cell. 2011;42:700-12 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Trinkle Mulcahy L, Chusainow J, Lam Y, Swift S, Lamond A. Visualization of intracellular PP1 targeting through transiently and stably expressed fluorescent protein fusions. Methods Mol Biol. 2007;365:133-54 pubmed
  • 免疫印迹; 小鼠
Bergman M, Teerlink J, Mahimkar R, Li L, Zhu B, Nguyen A, et al. Cardiac matrix metalloproteinase-2 expression independently induces marked ventricular remodeling and systolic dysfunction. Am J Physiol Heart Circ Physiol. 2007;292:H1847-60 pubmed
  • 免疫沉淀; 人类
Kari B, Lussenhop N, Goertz R, Wabuke Bunoti M, Radeke R, Gehrz R. Characterization of monoclonal antibodies reactive to several biochemically distinct human cytomegalovirus glycoprotein complexes. J Virol. 1986;60:345-52 pubmed
Bewley M, Gautam L, Jagadeeshaprasad M, Gowda D, Flanagan J. Molecular architecture and domain arrangement of the placental malaria protein VAR2CSA suggests a model for carbohydrate binding. J Biol Chem. 2020;295:18589-18603 pubmed 出版商
Zhao L, Han X, Lu J, McEachern D, Wang S. A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo. Neoplasia. 2020;22:522-532 pubmed 出版商
Schüchner S, Behm C, Mudrak I, Ogris E. The Myc tag monoclonal antibody 9E10 displays highly variable epitope recognition dependent on neighboring sequence context. Sci Signal. 2020;13: pubmed 出版商
Pedrosa A, Bodrug N, Gómez Escudero J, Carter E, Reynolds L, Georgiou P, et al. Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861. Cancer Res. 2019;: pubmed 出版商
Ida K, Miyamoto T, Higuchi S, Takeuchi H, Yamada S, Ono M, et al. Effectiveness of a genetic test panel designed for gynecological cancer: an exploratory study. Med Oncol. 2019;36:62 pubmed 出版商
Morioka S, Perry J, Raymond M, Medina C, Zhu Y, Zhao L, et al. Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release. Nature. 2018;563:714-718 pubmed 出版商
Wu J, Fan W, Ma L, Geng X. miR-708-5p promotes fibroblast-like synoviocytes' cell apoptosis and ameliorates rheumatoid arthritis by the inhibition of Wnt3a/β-catenin pathway. Drug Des Devel Ther. 2018;12:3439-3447 pubmed 出版商
Rodríguez Muela N, Parkhitko A, Grass T, Gibbs R, Norabuena E, Perrimon N, et al. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes. J Clin Invest. 2018;128:3008-3023 pubmed 出版商
Mahadevan S, Sathappan V, Utama B, Lorenzo I, Kaskar K, Van den Veyver I. Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming. Sci Rep. 2017;7:44667 pubmed 出版商
van der Kant R, Jonker C, Wijdeven R, Bakker J, Janssen L, Klumperman J, et al. Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity. J Biol Chem. 2015;290:30280-90 pubmed 出版商
da Costa J, Carvalhais V, Amado F, Silva A, Nogueira Ferreira R, Ferreira R, et al. Anti-tumoral activity of human salivary peptides. Peptides. 2015;71:170-8 pubmed 出版商
Jang K, Mano H, Aoki K, Hayashi T, Muto A, Nambu Y, et al. Mitochondrial function provides instructive signals for activation-induced B-cell fates. Nat Commun. 2015;6:6750 pubmed 出版商
Pekkurnaz G, Trinidad J, Wang X, Kong D, Schwarz T. Glucose regulates mitochondrial motility via Milton modification by O-GlcNAc transferase. Cell. 2014;158:54-68 pubmed 出版商
Barnett T, Liebl D, Seymour L, Gillen C, Lim J, LaRock C, et al. The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication. Cell Host Microbe. 2013;14:675-82 pubmed 出版商
Hsieh Y, Chou M, Chen H, Tseng J. IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1. Gynecol Oncol. 2013;131:182-90 pubmed 出版商
Hubbi M, Hu H, Kshitiz -, Gilkes D, Semenza G. Sirtuin-7 inhibits the activity of hypoxia-inducible factors. J Biol Chem. 2013;288:20768-75 pubmed 出版商
Megill A, Lee T, Dibattista A, Song J, Spitzer M, Rubinshtein M, et al. A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis. J Neurosci. 2013;33:9306-18 pubmed 出版商
Wang H, Shi L, Wong C, Han X, Hwang P, Truong L, et al. The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair. PLoS Genet. 2013;9:e1003277 pubmed 出版商
Lu C, Truong L, Aslanian A, Shi L, Li Y, Hwang P, et al. The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination. J Biol Chem. 2012;287:43984-94 pubmed 出版商
Al Sorkhy M, Ferraiuolo R, Jalili E, Malysa A, Fratiloiu A, Sloane B, et al. The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer. BMC Cancer. 2012;12:45 pubmed 出版商
Kim M, Jung J, Mo J, Ann E, Ahn J, Yoon J, et al. The intracellular domain of Jagged-1 interacts with Notch1 intracellular domain and promotes its degradation through Fbw7 E3 ligase. Exp Cell Res. 2011;317:2438-46 pubmed 出版商
Murri Plesko M, Hulikova A, Oosterwijk E, Scott A, Zortea A, Harris A, et al. Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX. Eur J Pharmacol. 2011;657:173-83 pubmed 出版商
Silvestri L, Pagani A, Camaschella C. Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. Blood. 2008;111:924-31 pubmed
Hilpert K, Hansen G, Wessner H, Kuttner G, Welfle K, Seifert M, et al. Anti-c-myc antibody 9E10: epitope key positions and variability characterized using peptide spot synthesis on cellulose. Protein Eng. 2001;14:803-6 pubmed
Bello Fernandez C, Packham G, Cleveland J. The ornithine decarboxylase gene is a transcriptional target of c-Myc. Proc Natl Acad Sci U S A. 1993;90:7804-8 pubmed
图像
图像 1 :
Novus Biologicals NB600-302 图像 1
Western Blot: c-Myc Antibody (9E10) [NB600-302] - CtIP is phosphorylated by CDKs at multiple sites. Myc-BRCA1 and/or HA-CtIP WT or indicated mutants were expressed in 293T cells and co-immunoprecipitation was performed. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pgen.1003277) licensed under a CC-BY licence.
产品信息
品牌 :
Novus
master code :
NB600-302
SKU号 :
NB600-302
产品名称 :
c Myc抗体(9E10)
描述 :
The c-Myc Antibody (9E10) from Novus Biologicals is a mouse monoclonal antibody to c-Myc. This antibody reacts with human, mouse, drosophila. The c-Myc Antibody (9E10) has been validated for the following applications: Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Flow (Intracellular).
靶标 :
c-Myc
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
9.00E+10
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
A synthetic peptide corresponding to amino acids 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) of human c-Myc Antibody (9E10). [UniProt# P01106]
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 果蝇
特异性 :
Specific for the c-myc protein in random coil configuration, not as a helix. 9E10 does not react with V-myc.
理论上的分子量 :
48.8 kDa
基因符号 :
Myc
catalog number base :
NB600-302
accessionNumbers :
P01106
应用 :
Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Flow (Intracellular)
2020美元 :
299
2021美元 :
299美元
别名 :
9E10 anti-Myc, 9E10 Myc, avian myelocytomatosis viral oncogene homolog, BHLHE39, bHLHe39MRTL, Class E basic helix-loop-helix protein 39, c-Myc, MYC, myc proto-oncogene protein, MYCC, myc-related translation/localization regulatory factor, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian)
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。