This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Aggrecan Antibody (BC-3)
目录 :
NB600-504
规格 :
0.025毫克
价格 :
129美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
BC-3
反应物种 :
人类, 大鼠, 牛
应用 :
免疫印迹, 免疫组化
文章摘录数: 22
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠
Yurube T, Takada T, Suzuki T, Kakutani K, Maeno K, Doita M, et al. Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration. Arthritis Res Ther. 2012;14:R51 pubmed 出版商
  • 免疫印迹; 大鼠
  • 免疫印迹; 牛
  • 免疫印迹; 人类
Swearingen C, Chambers M, Lin C, Marimuthu J, Rito C, Carter Q, et al. A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs. Osteoarthritis Cartilage. 2010;18:1159-66 pubmed 出版商
Hurley Novatny A, Arumugasaamy N, Kimicata M, Baker H, Mikos A, Fisher J. Concurrent multi-lineage differentiation of mesenchymal stem cells through spatial presentation of growth factors. Biomed Mater. 2020;15:055035 pubmed 出版商
Si H, Yang T, Li L, Tian M, Zhou L, Li D, et al. miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence. Mol Ther Nucleic Acids. 2020;19:15-30 pubmed 出版商
Kimura N, Nakagami G, Minematsu T, Sanada H. Non-invasive detection of local tissue responses to predict pressure ulcer development in mouse models. J Tissue Viability. 2020;29:51-57 pubmed 出版商
Cheng B, Liu Y, Zhao Y, Li Q, Liu Y, Wang J, et al. The role of anthrax toxin protein receptor 1 as a new mechanosensor molecule and its mechanotransduction in BMSCs under hydrostatic pressure. Sci Rep. 2019;9:12642 pubmed 出版商
Larocca T, Mariani A, Watkins L, Link C. TDP-43 knockdown causes innate immune activation via protein kinase R in astrocytes. Neurobiol Dis. 2019;:104514 pubmed 出版商
Liu Z, Zhang Z, Zhang A, Zhang F, Du W, Zhang Y, et al. Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells. Biosci Rep. 2019;39: pubmed 出版商
Chen L, Liu G, Li W, Wu X. Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system. Cell Mol Biol Lett. 2019;24:16 pubmed 出版商
Zhong Y, Zhang Y, Xu J, Zhou J, Liu J, Ye M, et al. Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Nanoparticles for Thrombolysis without Vascular Damage: A Synergistic Nonpharmaceutical Strategy. ACS Nano. 2019;13:3387-3403 pubmed 出版商
Cheng Q, Tong F, Shen Y, He C, Wang C, Ding F. Achyranthes bidentata polypeptide k improves long-term neurological outcomes through reducing downstream microvascular thrombosis in experimental ischemic stroke. Brain Res. 2019;1706:166-176 pubmed 出版商
Jia J, Wang S, Ma L, Yu J, Guo Y, Wang C. The Differential Effects of Leukocyte-Containing and Pure Platelet-Rich Plasma on Nucleus Pulposus-Derived Mesenchymal Stem Cells: Implications for the Clinical Treatment of Intervertebral Disc Degeneration. Stem Cells Int. 2018;2018:7162084 pubmed 出版商
Yang D, Zhu D, Zhu S, Feng F, Gong C, Chen C, et al. 17β-Estradiol/extrogen receptor β alleviates apoptosis and enhances matrix biosynthesis of nucleus pulposus cells through regulating oxidative damage under a high glucose condition. Biomed Pharmacother. 2018;107:1004-1009 pubmed 出版商
Priyadarshini R, Hussain M, Attri P, Kaur E, Tripathi V, Priya S, et al. BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor. Cell Rep. 2018;24:947-961.e7 pubmed 出版商
Hiebert P, WIETECHA M, Cangkrama M, Haertel E, Mavrogonatou E, Stumpe M, et al. Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome. Dev Cell. 2018;46:145-161.e10 pubmed 出版商
Mallikarjuna P, Sitaram R, Landström M, Ljungberg B. VHL status regulates transforming growth factor-β signaling pathways in renal cell carcinoma. Oncotarget. 2018;9:16297-16310 pubmed 出版商
Ma S, Xie Z, Guo Y, Yu J, Lu J, Zhang W, et al. Effect of Acupotomy on FAK-PI3K Signaling Pathways in KOA Rabbit Articular Cartilages. Evid Based Complement Alternat Med. 2017;2017:4535326 pubmed 出版商
Gerenu G, Martisova E, Ferrero H, Carracedo M, Rantamäki T, Ramirez M, et al. Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits. Biochim Biophys Acta Mol Basis Dis. 2017;1863:991-1001 pubmed 出版商
Han M, Kim S, Kim H, Yim H, Bencherif S, Kim T, et al. Extracellular matrix-based cryogels for cartilage tissue engineering. Int J Biol Macromol. 2016;93:1410-1419 pubmed 出版商
Sitaram R, Mallikarjuna P, Landström M, Ljungberg B. Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma. Oncotarget. 2016;7:35917-35931 pubmed 出版商
Bouhenni R, Hart M, Al Jastaneiah S, Alkatan H, Edward D. Immunohistochemical expression and distribution of proteoglycans and collagens in sclerocornea. Int Ophthalmol. 2013;33:691-700 pubmed 出版商
Little C, Hughes C, Curtis C, Janusz M, Bohne R, Wang Weigand S, et al. Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation. Matrix Biol. 2002;21:271-88 pubmed
产品信息
品牌 :
Novus
master code :
NB600-504
SKU号 :
NB600-504.025毫克
产品名称 :
Aggrecan Antibody (BC-3)
描述 :
The Aggrecan Antibody (BC-3) from Novus Biologicals is a mouse monoclonal antibody to Aggrecan. This antibody reacts with human, mouse, rat, porcine, bovine, canine, equine, feline, guinea pig, rabbit, sheep. The Aggrecan Antibody (BC-3) has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
靶标 :
Aggrecan
类别 :
一抗
单位尺寸 :
0.025毫克
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
BC-3
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
ARGSV。 合成肽共轭标签
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质A或G纯化
物种 :
Human, Mouse, Rat, Porcine, Bovine, Canine, Equine, Feline, Guinea Pig, Rabbit, Sheep
特异性 :
Recognizes the aggrecanase (ADAMTS-1, -4 & -5)-generated N-terminal neoepitope ARG after cleavage between amino acids EGE and ARG within the interglobular domain of aggrecanase-catabolised aggrecan.
理论上的分子量 :
250 kDa
基因符号 :
ACAN
catalog number base :
NB600-504
accessionNumbers :
P16112
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡, 免疫组化冷冻
2020美元 :
129
2021美元 :
129美元
别名 :
AGC1SEDK, aggrecan, aggrecan core protein, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan 1, Chondroitin sulfate proteoglycan core protein 1, CSPCP, CSPG1aggrecan 1, CSPGCP, large aggregating proteoglycan, MSK16AGCAN
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。