产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
SREBP1抗体(2A4)
目录 :
NB600-582
规格 :
0.1 ml (also 0.025 ml)
价格 :
349美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
DyLight系列染料550
克隆名称 :
2A4
反应物种 :
仓鼠, 人类, 小鼠, 大鼠, 犬, 鸡
应用 :
免疫印迹, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 41
出版应用/物种/样本/稀释 | 参考文献 |
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| Gosmain Y, Dif N, Berbe V, Loizon E, Rieusset J, Vidal H, et al. Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues. J Lipid Res. 2005;46:697-705 pubmed
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| Zhang Y, Hillgartner F. Starvation and feeding a high-carbohydrate, low-fat diet regulate the expression sterol regulatory element-binding protein-1 in chickens. J Nutr. 2004;134:2205-10 pubmed
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| Demoulin J, Ericsson J, Kallin A, Rorsman C, Ronnstrand L, Heldin C. Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins. J Biol Chem. 2004;279:35392-402 pubmed
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| Yin L, Zhang Y, Hillgartner F. Sterol regulatory element-binding protein-1 interacts with the nuclear thyroid hormone receptor to enhance acetyl-CoA carboxylase-alpha transcription in hepatocytes. J Biol Chem. 2002;277:19554-65 pubmed
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| Sato R, Yang J, Wang X, Evans M, Ho Y, Goldstein J, et al. Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1). J Biol Chem. 1994;269:17267-73 pubmed
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| Sheng Z, Otani H, Brown M, Goldstein J. Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver. Proc Natl Acad Sci U S A. 1995;92:935-8 pubmed
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Kim H, Miyazaki M, Ntambi J. Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism. J Lipid Res. 2002;43:1750-7 pubmed
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Shimano H, Shimomura I, Hammer R, Herz J, Goldstein J, Brown M, et al. Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. J Clin Invest. 1997;100:2115-24 pubmed
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图像
图像 1 :
Western Blot: SREBP1 Antibody (2A4) [NB600-582] - Hepatic SREBP1c and SREBP2 protein abundance in C57BL/6 mice assigned to a high-fat (HF) or a high-fat/exercise (HF + EX) group for 8 weeks. Cytosolic and nuclear SREBP1c abundance. Image collected and cropped by CiteAb from the following publication (http://www.hindawi.com/journals/jl/2013/908048/), licensed under a CC-BY licence.
产品信息
品牌 :
Novus
SKU号 :
NB600-582
产品名称 :
SREBP1抗体(2A4)
单位尺寸 :
0.1 ml (also 0.025 ml)
描述 :
The SREBP1 Antibody (2A4) from Novus is a mouse monoclonal antibody to SREBP1. This antibody reacts with human, mouse, rat, canine, chicken, hamster, monkey, golden syrian hamster. The SREBP1 Antibody (2A4) has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry-Frozen, Knockout Validated.
靶标 :
SREBP1
类别 :
一抗
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
2A4
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
6 His-tag fusion protein of human SREBP1 corresponding to amino acids 301-407. [UniProt# P36956]
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
Human, Mouse, Rat, Canine, Chicken, Hamster, Monkey, Golden Syrian Hamster
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
用途 :
This SREBP1 (clone 2A4) antibody is useful for WB where a band can be seen at 125 kDa (precursor) and additional bands may be seen at 60-70 kDa (cleaved). In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue. The use of this antibody in IHC paraffin embedded tissue has been questionable.
基因符号 :
SREBF1
catalog number base :
NB600-582
accessionNumbers :
P36956
应用 :
Western Blot, Simple Western, Immunohistochemistry-Frozen, Knockout Validated
美元 :
349美元
default size :
TRUE
别名 :
BHLHD1, Class D basic helix-loop-helix protein 1, SREBP 1c, SREBP-1, SREBP1bHLHd1SREBP-1c, sterol regulatory element binding protein-1, sterol regulatory element binding transcription factor 1, sterol regulatory element-binding protein 1, Sterol regulatory element-binding transcription factor 1
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。