产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
TOR/哺乳动物雷帕霉素靶蛋白[p Ser2448]抗体
目录 :
NB600-607
规格 :
0.1毫克
价格 :
549美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
S68
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, activation, 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 11
参考文献
Serafin V, Porcù E, Cortese G, Mariotto E, Veltri G, Bresolin S, et al. SYK Targeting Represents a Potential Therapeutic Option for Relapsed Resistant Pediatric ETV6-RUNX1 B-Acute Lymphoblastic Leukemia Patients. Int J Mol Sci. 2019;20: pubmed 出版商
Cappoli N, Mezzogori D, Tabolacci E, Coletta I, Navarra P, Pani G, et al. The mTOR kinase inhibitor rapamycin enhances the expression and release of pro-inflammatory cytokine interleukin 6 modulating the activation of human microglial cells. EXCLI J. 2019;18:779-798 pubmed 出版商
Lisi L, Ciotti G, Chiavari M, Pizzoferrato M, Mangiola A, Kalinin S, et al. Phospho-mTOR expression in human glioblastoma microglia-macrophage cells. Neurochem Int. 2019;129:104485 pubmed 出版商
Chiavari M, Ciotti G, Navarra P, Lisi L. Pro-Inflammatory Activation of A New Immortalized Human Microglia Cell Line. Brain Sci. 2019;9: pubmed 出版商
Zhou X, Yue G, Chan A, Tsui S, Fung K, Sun H, et al. Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer. Biochem Pharmacol. 2017;142:58-70 pubmed 出版商
Juraszek B, Nałęcz K. Protein phosphatase PP2A - a novel interacting partner of carnitine transporter OCTN2 (SLC22A5) in rat astrocytes. J Neurochem. 2016;139:537-551 pubmed 出版商
Tanti G, Goswami S. SG2NA recruits DJ-1 and Akt into the mitochondria and membrane to protect cells from oxidative damage. Free Radic Biol Med. 2014;75:1-13 pubmed 出版商
Tran H, Bustos D, Yeh R, Rubinfeld B, Lam C, Shriver S, et al. HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction. J Biol Chem. 2013;288:3753-67 pubmed 出版商
Moreno C, Lane W, Pallas D. A mammalian homolog of yeast MOB1 is both a member and a putative substrate of striatin family-protein phosphatase 2A complexes. J Biol Chem. 2001;276:24253-60 pubmed
Yu X, Du X, Moreno C, Green R, Ogris E, Feng Q, et al. Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigen. Mol Biol Cell. 2001;12:185-99 pubmed
Moreno C, Park S, Nelson K, Ashby D, Hubalek F, Lane W, et al. WD40 repeat proteins striatin and S/G(2) nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein phosphatase 2A. J Biol Chem. 2000;275:5257-63 pubmed
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB600-607
SKU号 :
NB600-607
产品名称 :
TOR/哺乳动物雷帕霉素靶蛋白[p Ser2448]抗体
描述 :
The TOR/mTOR [p Ser2448] Antibody from Novus is a rabbit polyclonal antibody to TOR/mTOR. This antibody reacts with human, rat. The TOR/mTOR [p Ser2448] Antibody has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, N/A.
靶标 :
TOR/哺乳动物雷帕霉素靶蛋白
类别 :
一抗
单位尺寸 :
0.1毫克
缓冲液 :
0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2
克隆性 :
多克隆
共轭标签 :
未共轭
宿主 :
兔
免疫原 :
TOR/TOR/mTOR [p Ser2448] Antibody was prepared from whole rabbit serum produced by repeated immunizations with a phosphorylated synthetic peptide corresponding a c-terminal region near Serine 2448 of human TOR/mTOR. (Uniprot: P42345)
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 大鼠
特异性 :
Reactivity occurs with phosphorylated mTOR from human derived tissues and cells
基因符号 :
哺乳动物雷帕霉素靶蛋白
accessionNumbers :
P42345, P42345, P42345, P42345, P42345
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫组化石蜡, N/A
美元 :
549美元
别名 :
EC 2.7.11.1, FK506 binding protein 12-rapamycin associated protein 1, FK506 binding protein 12-rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FLJ44809, FRAP, FRAP1FKBP12-rapamycin complex-associated protein 1, FRAP2, Mammalian target of rapamycin, Mechanistic target of rapamycin, mechanistic target of rapamycin (serine/threonine kinase), mTOR, RAFT1, rapamycin and FKBP12 target 1, rapamycin associated protein FRAP2, Rapamycin target protein 1, RAPT1FKBP-rapamycin associated protein, serine/threonine-protein kinase mTOR
储存 :
Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。