产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
ZEB1抗体
目录 :
NBP1-05987
规格 :
0.1毫升
价格 :
429美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 51
参考文献
Schuhwerk H, Kleemann J, Gupta P, van Roey R, Armstark I, Kreileder M, et al. The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response. Cell Rep. 2022;41:111819 pubmed 出版商
Han B, Jung K, Lee J, Yoon Y, Ko S, Park M, et al. Lidocaine enhances the efficacy of palbociclib in triple-negative breast cancer. Am J Cancer Res. 2022;12:3083-3098 pubmed
Ichikawa M, Endo K, Itoh Y, Osada A, Kimura Y, Ueki K, et al. Ets family proteins regulate the EMT transcription factors Snail and ZEB in cancer cells. FEBS Open Bio. 2022;12:1353-1364 pubmed 出版商
Yoshioka H, Suzuki A, Iwaya C, Iwata J. Suppression of microRNA 124-3p and microRNA 340-5p ameliorates retinoic acid-induced cleft palate in mice. Development. 2022;149: pubmed 出版商
Choi S, Kim J, Chen C, Wu C, Marco M, Barriga F, et al. KRAS Mutants Upregulate Integrin β4 to Promote Invasion and Metastasis in Colorectal Cancer. Mol Cancer Res. 2022;20:1305-1319 pubmed 出版商
Kang E, Jung S, Nam S, Park Y, Seo S, Park K, et al. Tissue miR-200c-3p and circulating miR-1290 as potential prognostic biomarkers for colorectal cancer. Sci Rep. 2022;12:2295 pubmed 出版商
Celik M, Celik Z. Role of the Immunohistochemical ZEB1 Expression in Uterine Mesenchymal Neoplasms. Int J Surg Pathol. 2022;:10668969211070180 pubmed 出版商
Wang J, Farkas C, Benyoucef A, Carmichael C, Haigh K, Wong N, et al. Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity. PLoS Biol. 2021;19:e3001394 pubmed 出版商
Lu J, Cao L, Xu Y, Huang X, Cho S, Ashktorab H, et al. FOXC1 modulates stem-like cell properties and chemoresistance through hedgehog and EMT signaling in gastric adenocarcinoma. Mol Ther. 2021;: pubmed 出版商
Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson M, Schmitz W, Wach S, et al. MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer. Nat Commun. 2021;12:5066 pubmed 出版商
Chen Y, Jiang K, Bai X, Liu M, Lin S, Xu T, et al. ZEB1 Induces Ddr1 Promoter Hypermethylation and Contributes to the Chronic Pain in Spinal Cord in Rats Following Oxaliplatin Treatment. Neurochem Res. 2021;46:2181-2191 pubmed 出版商
Wojnarowicz P, Escolano M, Huang Y, Desai B, Chin Y, Shah R, et al. Anti-tumor effects of an ID antagonist with no observed acquired resistance. NPJ Breast Cancer. 2021;7:58 pubmed 出版商
Carstens J, Yang S, Correa de Sampaio P, Zheng X, Barua S, McAndrews K, et al. Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer. Cell Rep. 2021;35:108990 pubmed 出版商
Li J, Luco A, Camirand A, St Arnaud R, Kremer R. Vitamin D Regulates CXCL12/CXCR4 and Epithelial-to-Mesenchymal Transition in a Model of Breast Cancer Metastasis to Lung. Endocrinology. 2021;162: pubmed 出版商
Pratheeshkumar P, Siraj A, Divya S, Parvathareddy S, Alobaisi K, Al Sobhi S, et al. CHD4 Predicts Aggressiveness in PTC Patients and Promotes Cancer Stemness and EMT in PTC Cells. Int J Mol Sci. 2021;22: pubmed 出版商
Neufert C, Heichler C, Brabletz T, Scheibe K, Boonsanay V, Greten F, et al. Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis. Nat Protoc. 2021;16:61-85 pubmed 出版商
Sáenz de Santa María I, Celada L, San José Martínez A, Cubiella T, Chiara M. Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2. Cancers (Basel). 2020;12: pubmed 出版商
Wilkinson M, Abramova E, Guo C, Gow J, Murray A, Koudelka A, et al. Fatty acid nitroalkenes inhibit the inflammatory response to bleomycin-mediated lung injury. Toxicol Appl Pharmacol. 2020;407:115236 pubmed 出版商
Sato K, Hikita H, Myojin Y, Fukumoto K, Murai K, Sakane S, et al. Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels. PLoS ONE. 2020;15:e0235573 pubmed 出版商
Huang C, Yoon C, Zhou X, Zhou Y, Zhou W, Liu H, et al. ERK1/2-Nanog signaling pathway enhances CD44(+) cancer stem-like cell phenotypes and epithelial-to-mesenchymal transition in head and neck squamous cell carcinomas. Cell Death Dis. 2020;11:266 pubmed 出版商
Horn L, Riskin J, Hempel H, Fousek K, Lind H, Hamilton D, et al. Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunity. J Immunother Cancer. 2020;8: pubmed 出版商
Ran J, Yang H, Huang H, Huang H, Xu Z, Zhang W, et al. ZEB1 modulates endometrial receptivity through epithelial-mesenchymal transition in endometrial epithelial cells in vitro. Biochem Biophys Res Commun. 2020;525:699-705 pubmed 出版商
Murata M, Ito T, Tanaka Y, Yamamura K, Furue K, Furue M. OVOL2-Mediated ZEB1 Downregulation May Prevent Promotion of Actinic Keratosis to Cutaneous Squamous Cell Carcinoma. J Clin Med. 2020;9: pubmed 出版商
Viswanathan K, Siddiqui M, Borczuk A. The diagnostic utility of zinc E-box 1 (ZEB1) transcription factor for identification of pulmonary sarcomatoid carcinoma in cytologic and surgical specimens. J Am Soc Cytopathol. 2020;9:55-61 pubmed 出版商
Wu R, Chen Z, Zhou W, Li Y, Huang Z, Lin D, et al. High expression of ZEB1 in endometriosis and its role in 17β-estradiol-induced epithelial-mesenchymal transition. Int J Clin Exp Pathol. 2018;11:4744-4758 pubmed
Miro C, Di Cicco E, Ambrosio R, Mancino G, Di Girolamo D, Cicatiello A, et al. Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch. Nat Commun. 2019;10:5410 pubmed 出版商
Osada A, Endo K, Kimura Y, Sakamoto K, Nakamura R, Sakamoto K, et al. Addiction of mesenchymal phenotypes on the FGF/FGFR axis in oral squamous cell carcinoma cells. PLoS ONE. 2019;14:e0217451 pubmed 出版商
Hah Y, Cho H, Jo S, Park Y, Heo E, Yoon T. Nicotinamide N‑methyltransferase induces the proliferation and invasion of squamous cell carcinoma cells. Oncol Rep. 2019;42:1805-1814 pubmed 出版商
Yoon C, Till J, Cho S, Chang K, Lin J, Huang C, et al. KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis. Mol Cancer Res. 2019;: pubmed 出版商
Sippel T, Johnson A, Li H, Hanson D, Nguyen T, Bullock B, et al. Activation of PPARγ in Myeloid Cells Promotes Progression of Epithelial Lung Tumors Through TGF-β1. Mol Cancer Res. 2019;: pubmed 出版商
Ordonez L, Hay T, McEwen R, Polanska U, Hughes A, Delpuech O, et al. Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours. Oncotarget. 2019;10:2586-2606 pubmed 出版商
Rios A, Capaldo B, Vaillant F, Pal B, van Ineveld R, Dawson C, et al. Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging. Cancer Cell. 2019;35:618-632.e6 pubmed 出版商
Katsuno Y, Meyer D, Zhang Z, Shokat K, Akhurst R, Miyazono K, et al. Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition. Sci Signal. 2019;12: pubmed 出版商
Fujiwara S, Saiki Y, Ishizawa K, Fukushige S, Yamanaka M, Sato M, et al. Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas. Cancer Med. 2019;8:1671-1678 pubmed 出版商
Jia D, Augert A, Kim D, Eastwood E, Wu N, Ibrahim A, et al. Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition. Cancer Discov. 2018;8:1422-1437 pubmed 出版商
Knaack H, Lenk L, Philipp L, Miarka L, Rahn S, Viol F, et al. Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells. Oncotarget. 2018;9:31771-31786 pubmed 出版商
Chen Y, LeBleu V, Carstens J, Sugimoto H, Zheng X, Malasi S, et al. Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. EMBO Mol Med. 2018;10: pubmed 出版商
Weng C, Chen L, Lin Y, Shih J, Lin Y, Tseng R, et al. Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI. Oncogene. 2019;38:455-468 pubmed 出版商
Cho S, Yoon C, Lee J, Chang K, Lin J, Kim Y, et al. KMT2C Mutations in Diffuse-Type Gastric Adenocarcinoma Promote Epithelial-to-Mesenchymal Transition. Clin Cancer Res. 2018;24:6556-6569 pubmed 出版商
Suzuki K, Kawataki T, Endo K, Miyazawa K, Kinouchi H, Saitoh M. Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade. Oncol Lett. 2018;16:1758-1764 pubmed 出版商
Chang K, Yoon C, Yi B, Tap W, Simon M, Yoon S. Platelet-derived growth factor receptor-α and -β promote cancer stem cell phenotypes in sarcomas. Oncogenesis. 2018;7:47 pubmed 出版商
Maturi V, Enroth S, Heldin C, Moustakas A. Genome-wide binding of transcription factor ZEB1 in triple-negative breast cancer cells. J Cell Physiol. 2018;233:7113-7127 pubmed 出版商
Maturi V, Morén A, Enroth S, Heldin C, Moustakas A. Genomewide binding of transcription factor Snail1 in triple-negative breast cancer cells. Mol Oncol. 2018;12:1153-1174 pubmed 出版商
Acharya K, Nettles S, Sellers K, Im D, Harling M, Pattanayak C, et al. The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent. Eneuro. 2017;4: pubmed 出版商
Lutz G, Jurak I, Kim E, Kim J, Hackenberg M, Leader A, et al. Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors. Viruses. 2017;9: pubmed 出版商
Liang X, Yuan X, Yu J, Wu Y, Li K, Sun C, et al. Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes. EBioMedicine. 2017;21:104-116 pubmed 出版商
Katsura A, Tamura Y, Hokari S, Harada M, Morikawa M, Sakurai T, et al. ZEB1-regulated inflammatory phenotype in breast cancer cells. Mol Oncol. 2017;11:1241-1262 pubmed 出版商
Kim Y, Choi Y, Lee J, Soh E, Kim J, Park T. Senescent tumor cells lead the collective invasion in thyroid cancer. Nat Commun. 2017;8:15208 pubmed 出版商
Yoon C, Cho S, Chang K, Park D, Ryeom S, Yoon S. Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma. Mol Cancer Res. 2017;15:1106-1116 pubmed 出版商
Wang Y, Xu X, Yu S, Jeong K, Zhou Z, Han L, et al. Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers. Genome Res. 2017;27:1112-1125 pubmed 出版商
Sinh N, Endo K, Miyazawa K, Saitoh M. Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells. Cancer Sci. 2017;108:952-960 pubmed 出版商
图像
图像 1 :
Novus Biologicals NBP1-05987 图像 1
Immunohistochemistry: ZEB1 Antibody [NBP1-05987] - Immunohistochemical staining results of EMT regulators in HG-PanIN: SNAIL, SLUG, TWIST1, and ZEB1. We categorized and defined three grades: grade 0, <10% positive staining; grade 1, 10%-50% positive; grade 2, 50%< positive Image collected and cropped by CiteAb from the following publication (https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.2016) licensed under a CC-BY licence.
产品信息
品牌 :
Novus
master code :
NBP1-05987
SKU号 :
NBP1-05987
产品名称 :
ZEB1抗体
描述 :
The ZEB1 Antibody from Novus is a rabbit polyclonal antibody to ZEB1. This antibody reacts with human, mouse, rat. The ZEB1 Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Gel Super Shift Assays, Microarray, Chromatin Immunoprecipitation (ChIP), Single Cell Western, Knockdown Validated.
靶标 :
ZEB1
类别 :
一抗
sizes available :
0.1毫升
缓冲液 :
TBS和0.1% BSA
克隆性 :
多克隆
浓度 :
0.2毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
The immunogen recognized by this antibody maps to a region between residue 1074 and 1124 of human zinc finger E-box binding homeobox 1 using the numbering given in entry NP_110378.3
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠
基因符号 :
ZEB1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ZEB1-Antibody-Immunohistochemistry-NBP1-05987-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ZEB1-Antibody-Western-Blot-NBP1-05987-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ZEB1-Antibody-Immunohistochemistry-Paraffin-NBP1-05987-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ZEB1-Antibody-Western-Blot-NBP1-05987-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ZEB1-Antibody-Immunohistochemistry-Paraffin-NBP1-05987-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ZEB1-Antibody-Immunohistochemistry-Paraffin-NBP1-05987-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/ZEB1-Antibody-Immunoprecipitation-NBP1-05987-img0013.jpg
accessionNumbers :
P37275
应用 :
Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Gel Super Shift Assays, Microarray, Chromatin Immunoprecipitation (ChIP), Single Cell Western, Knockdown Validated
美元 :
429美元
别名 :
AREB6MGC133261, delta-crystallin enhancer binding factor 1, DELTAEF1, FECD6, Negative regulator of IL2, NIL2A, NIL-2-A, NIL-2-A zinc finger protein, posterior polymorphous corneal dystrophy 3, PPCD3, TCF-8, TCF8BZP, Transcription factor 8, transcription factor 8 (represses interleukin 2 expression), ZEB, Zfhep, ZFHX1A, zinc finger E-box binding homeobox 1, zinc finger E-box-binding homeobox 1, zinc finger homeodomain enhancer-binding protein
储存 :
存放在4C。 不冻结
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。