产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
组蛋白H3[三甲基化Lys9]抗体(6F12-H4)
目录 :
NBP1-30141
规格 :
0.1 ml (also 0.025 ml)
价格 :
379美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6F12-H4
反应物种 :
人类, 小鼠, 大鼠, pigs
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 72
出版应用/物种/样本/稀释参考文献
  • 免疫组化; pigs ; 1:100; 图 3c
  • 免疫印迹; pigs ; 图 1b
No J, Choi M, Kwon D, Yoo J, Yang B, Park J, et al. Cell-free extract from porcine induced pluripotent stem cells can affect porcine somatic cell nuclear reprogramming. J Reprod Dev. 2015;61:90-8 pubmed 出版商
  • 免疫印迹; 小鼠
Krapivinsky G, Krapivinsky L, Manasian Y, Clapham D. The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase. Cell. 2014;157:1061-72 pubmed 出版商
  • 免疫印迹; 小鼠
Cornacchia D, Dileep V, Quivy J, Foti R, Tili F, Santarella Mellwig R, et al. Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells. EMBO J. 2012;31:3678-90 pubmed 出版商
Saleh T, El Sadoni M, Alhesa A, Awad H, Jaradat M, Al Hazaimeh M, et al. Expression of Senescence and Apoptosis Biomarkers in Synchronous Bilateral Breast Cancer: A Case Report. Curr Oncol. 2021;28:3836-3845 pubmed 出版商
Hollenstein D, Gérecová G, Romanov N, Ferrari J, Veis J, Janschitz M, et al. A phosphatase-centric mechanism drives stress signaling response. EMBO Rep. 2021;22:e52476 pubmed 出版商
Božič J, Motaln H, Janež A, Markič L, Tripathi P, Yamoah A, et al. Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA. Brain. 2021;: pubmed 出版商
Saleh T, Alhesa A, Al Balas M, Abuelaish O, Mansour A, Awad H, et al. Expression of therapy-induced senescence markers in breast cancer samples upon incomplete response to neoadjuvant chemotherapy. Biosci Rep. 2021;41: pubmed 出版商
Perea García A, Miró P, Jiménez Lorenzo R, Martínez Pastor M, Puig S. Sequential recruitment of the mRNA decay machinery to the iron-regulated protein Cth2 in Saccharomyces cerevisiae. Biochim Biophys Acta Gene Regul Mech. 2020;1863:194595 pubmed 出版商
Qian Y, Li Y, Zheng C, Lu T, Sun R, Mao Y, et al. High methylation levels of histone H3 lysine 9 associated with activation of hypoxia-inducible factor 1α (HIF-1α) predict patients' worse prognosis in human hepatocellular carcinomas. Cancer Genet. 2020;245:17-26 pubmed 出版商
Bergstrand S, Böhm S, Malmgren H, Norberg A, Sundin M, Nordgren A, et al. Biallelic mutations in WRAP53 result in dysfunctional telomeres, Cajal bodies and DNA repair, thereby causing Hoyeraal-Hreidarsson syndrome. Cell Death Dis. 2020;11:238 pubmed 出版商
O Dea R, Santocanale C. Non-canonical regulation of homologous recombination DNA repair by the USP9X deubiquitylase. J Cell Sci. 2020;133: pubmed 出版商
Cebrià Costa J, Pascual Reguant L, Gonzalez Perez A, Serra Bardenys G, Querol J, Cosín M, et al. LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells. Oncogene. 2020;39:79-121 pubmed 出版商
Jin S, Cordes N. ATM controls DNA repair and mitochondria transfer between neighboring cells. Cell Commun Signal. 2019;17:144 pubmed 出版商
Hollenstein D, Gómez Sánchez R, Ciftci A, Kriegenburg F, Mari M, Torggler R, et al. Vac8 spatially confines autophagosome formation at the vacuole in S. cerevisiae. J Cell Sci. 2019;132: pubmed 出版商
Zhang W, Liao C, Chtatou H, Incrocci L, van Gent D, Van Weerden W, et al. Apalutamide Sensitizes Prostate Cancer to Ionizing Radiation via Inhibition of Non-Homologous End-Joining DNA Repair. Cancers (Basel). 2019;11: pubmed 出版商
van Drogen F, Mishra R, Rudolf F, Walczak M, Lee S, Reiter W, et al. Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5. J Cell Biol. 2019;218:3117-3133 pubmed 出版商
Janschitz M, Romanov N, Varnavides G, Hollenstein D, Gérecová G, Ammerer G, et al. Novel interconnections of HOG signaling revealed by combined use of two proteomic software packages. Cell Commun Signal. 2019;17:66 pubmed 出版商
He B, Gnawali N, Hinman A, Mattingly A, Osimani A, Cimini D. Chromosomes missegregated into micronuclei contribute to chromosomal instability by missegregating at the next division. Oncotarget. 2019;10:2660-2674 pubmed 出版商
Yost K, Clatterbuck Soper S, Walker R, Pineda M, Zhu Y, Ester C, et al. Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells. Sci Rep. 2019;9:4544 pubmed 出版商
Zhou M, Li Y, Lin S, Chen Y, Qian Y, Zhao Z, et al. H3K9me3, H3K36me3, and H4K20me3 Expression Correlates with Patient Outcome in Esophageal Squamous Cell Carcinoma as Epigenetic Markers. Dig Dis Sci. 2019;: pubmed 出版商
Stixova L, Komůrková D, Svobodová Kovaříková A, Bartova E. UVA irradiation strengthened an interaction between UBF1/2 proteins and H4K20 di-/tri-methylation. Chromosome Res. 2019;27:41-55 pubmed 出版商
Li Y, Guo D, Sun R, Chen P, Qian Q, Fan H. Methylation Patterns of Lys9 and Lys27 on Histone H3 Correlate with Patient Outcome in Gastric Cancer. Dig Dis Sci. 2019;64:439-446 pubmed 出版商
Zhao C, Shi J, Zhou R, He X, Yang H, Wu Z. DZNep and UNC0642 enhance in vitro developmental competence of cloned pig embryos. Reproduction. 2018;157:359-369 pubmed 出版商
Shine E, Xue M, Patel J, Healy A, Surovtseva Y, Herzon S, et al. Model Colibactins Exhibit Human Cell Genotoxicity in the Absence of Host Bacteria. ACS Chem Biol. 2018;13:3286-3293 pubmed 出版商
Chakraborty P, Huang J, Hiom K. DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing. Nat Commun. 2018;9:4346 pubmed 出版商
Peterson J, Wang D, Shettigar V, Roof S, Canan B, Bakkar N, et al. NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model. Nat Commun. 2018;9:3431 pubmed 出版商
Bayley R, Blakemore D, Cancian L, Dumon S, Volpe G, Ward C, et al. MYBL2 Supports DNA Double Strand Break Repair in Hematopoietic Stem Cells. Cancer Res. 2018;78:5767-5779 pubmed 出版商
Kang Y, Yan C. Regulation of DNA repair in the absence of classical non-homologous end joining. DNA Repair (Amst). 2018;68:34-40 pubmed 出版商
Kai Y, Li Y, Sun T, Yin W, Mao Y, Li J, et al. A medial prefrontal cortex-nucleus acumens corticotropin-releasing factor circuitry for neuropathic pain-increased susceptibility to opioid reward. Transl Psychiatry. 2018;8:100 pubmed 出版商
Bueno M, Baldascini M, Richard S, Lowndes N. Recruitment of lysine demethylase 2A to DNA double strand breaks and its interaction with 53BP1 ensures genome stability. Oncotarget. 2018;9:15915-15930 pubmed 出版商
Borude P, Bhushan B, Apte U. DNA Damage Response Regulates Initiation of Liver Regeneration Following Acetaminophen Overdose. Gene Expr. 2018;18:115-123 pubmed 出版商
Biswas U, Stevense M, Jessberger R. SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage. Curr Biol. 2018;28:249-261.e4 pubmed 出版商
Hassan S, Esch A, Liby T, Gray J, Heiser L. Pathway-Enriched Gene Signature Associated with 53BP1 Response to PARP Inhibition in Triple-Negative Breast Cancer. Mol Cancer Ther. 2017;16:2892-2901 pubmed 出版商
Bao X, Siprashvili Z, Zarnegar B, Shenoy R, Rios E, Nady N, et al. CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue. Dev Cell. 2017;43:227-239.e5 pubmed 出版商
Sivanand S, Rhoades S, Jiang Q, Lee J, Benci J, Zhang J, et al. Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination. Mol Cell. 2017;67:252-265.e6 pubmed 出版商
Foskolou I, Jorgensen C, Leszczynska K, Olcina M, Tarhonskaya H, Haisma B, et al. Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication. Mol Cell. 2017;66:206-220.e9 pubmed 出版商
Romanov N, Hollenstein D, Janschitz M, Ammerer G, Anrather D, Reiter W. Identifying protein kinase-specific effectors of the osmostress response in yeast. Sci Signal. 2017;10: pubmed 出版商
Ho T, Warr M, Adelman E, Lansinger O, Flach J, Verovskaya E, et al. Autophagy maintains the metabolism and function of young and old stem cells. Nature. 2017;543:205-210 pubmed 出版商
Li S, Shu F, Li Z, Jaafar L, Zhao S, Dynan W. Cell-type specific role of the RNA-binding protein, NONO, in the DNA double-strand break response in the mouse testes. DNA Repair (Amst). 2017;51:70-78 pubmed 出版商
Cheng L, Tan V, Ganesan S, Drake J. Integrating phosphoproteomics into the clinical management of prostate cancer. Clin Transl Med. 2017;6:9 pubmed 出版商
Kang Y, Balter B, Csizmadia E, Haas B, Sharma H, Bronson R, et al. Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. Nat Commun. 2017;8:14013 pubmed 出版商
Demaria M, O Leary M, Chang J, Shao L, Liu S, Alimirah F, et al. Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse. Cancer Discov. 2017;7:165-176 pubmed 出版商
Jaafar L, Li Z, Li S, Dynan W. SFPQ•NONO and XLF function separately and together to promote DNA double-strand break repair via canonical nonhomologous end joining. Nucleic Acids Res. 2017;45:1848-1859 pubmed 出版商
Dilley R, Verma P, Cho N, Winters H, Wondisford A, Greenberg R. Break-induced telomere synthesis underlies alternative telomere maintenance. Nature. 2016;539:54-58 pubmed 出版商
Moureau S, Luessing J, Harte E, Voisin M, Lowndes N. A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining. Open Biol. 2016;6: pubmed
Moreno A, Carrington J, Albergante L, Al Mamun M, Haagensen E, Komseli E, et al. Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells. Proc Natl Acad Sci U S A. 2016;113:E5757-64 pubmed 出版商
Nandakumar V, Hansen N, Glenn H, Han J, Helland S, Hernandez K, et al. Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells. Sci Rep. 2016;6:30593 pubmed 出版商
Saredi G, Huang H, Hammond C, Alabert C, Bekker Jensen S, Forne I, et al. H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex. Nature. 2016;534:714-718 pubmed 出版商
Pederiva C, Böhm S, Julner A, Farnebo M. Splicing controls the ubiquitin response during DNA double-strand break repair. Cell Death Differ. 2016;23:1648-57 pubmed 出版商
Rassoolzadeh H, Böhm S, Hedström E, Gad H, Helleday T, Henriksson S, et al. Overexpression of the scaffold WD40 protein WRAP53β enhances the repair of and cell survival from DNA double-strand breaks. Cell Death Dis. 2016;7:e2267 pubmed 出版商
Avila A, Illing A, Becker F, Maerz L, Morita Y, Philipp M, et al. Xpg limits the expansion of haematopoietic stem and progenitor cells after ionising radiation. Nucleic Acids Res. 2016;44:6252-61 pubmed 出版商
Byrd P, Stewart G, Smith A, Eaton C, Taylor A, Guy C, et al. A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development. PLoS Genet. 2016;12:e1005945 pubmed 出版商
Surovtseva Y, Jairam V, Salem A, Sundaram R, Bindra R, Herzon S. Characterization of Cardiac Glycoside Natural Products as Potent Inhibitors of DNA Double-Strand Break Repair by a Whole-Cell Double Immunofluorescence Assay. J Am Chem Soc. 2016;138:3844-55 pubmed 出版商
Mackenzie K, Carroll P, Lettice L, TarnauskaitÄ— Å, Reddy K, Dix F, et al. Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response. EMBO J. 2016;35:831-44 pubmed 出版商
Rassoolzadeh H, Coucoravas C, Farnebo M. The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1. Nucleus. 2015;6:417-24 pubmed 出版商
Park J, Welner R, Chan M, Troppito L, Staber P, Tenen D, et al. The DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining. J Immunol. 2016;196:244-55 pubmed 出版商
Hausmann C, Temme A, Cordes N, Eke I. ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation. Oncotarget. 2015;6:34592-605 pubmed 出版商
Hedstrom E, Pederiva C, Farnebo J, Nodin B, Jirstrom K, Brennan D, et al. Downregulation of the cancer susceptibility protein WRAP53β in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcome. Cell Death Dis. 2015;6:e1892 pubmed 出版商
Boysen G, Barbieri C, Prandi D, Blattner M, Chae S, Dahija A, et al. SPOP mutation leads to genomic instability in prostate cancer. elife. 2015;4: pubmed 出版商
Anbalagan S, Biasoli D, Leszczynska K, Mukherjee S, Hammond E. In Vitro Radiosensitization of Esophageal Cancer Cells with the Aminopeptidase Inhibitor CHR-2797. Radiat Res. 2015;184:259-65 pubmed 出版商
Hartlerode A, Morgan M, Wu Y, Buis J, Ferguson D. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors. Nat Struct Mol Biol. 2015;22:736-43 pubmed 出版商
Dickreuter E, Eke I, Krause M, Borgmann K, van Vugt M, Cordes N. Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells. Oncogene. 2016;35:1353-62 pubmed 出版商
Wilson C, Jurk D, Fullard N, Banks P, Page A, Luli S, et al. NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat Commun. 2015;6:6818 pubmed 出版商
Raymond A, Benhamouche S, Neaud V, Di Martino J, Javary J, Rosenbaum J. Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma. PLoS ONE. 2015;10:e0123333 pubmed 出版商
Gallina I, Colding C, Henriksen P, Beli P, Nakamura K, Offman J, et al. Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. Nat Commun. 2015;6:6533 pubmed 出版商
Luo Z, Feng X, Wang H, Xu W, Zhao Y, Ma W, et al. Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression. Aging Cell. 2015;14:391-9 pubmed 出版商
Kondratova A, Watanabe T, Marotta M, Cannon M, Segall A, Serre D, et al. Replication fork integrity and intra-S phase checkpoint suppress gene amplification. Nucleic Acids Res. 2015;43:2678-90 pubmed 出版商
Marin Vicente C, Domingo Prim J, Eberle A, Visa N. RRP6/EXOSC10 is required for the repair of DNA double-strand breaks by homologous recombination. J Cell Sci. 2015;128:1097-107 pubmed 出版商
Goglia A, Delsite R, Luz A, Shahbazian D, Salem A, Sundaram R, et al. Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors. Mol Cancer Ther. 2015;14:326-42 pubmed 出版商
Hosler G, Davoli T, Mender I, Litzner B, Choi J, Kapur P, et al. A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT. J Cutan Pathol. 2015;42:108-17 pubmed 出版商
Herraiz A, Belles X, Piulachs M. Chorion formation in panoistic ovaries requires windei and trimethylation of histone 3 lysine 9. Exp Cell Res. 2014;320:46-53 pubmed 出版商
Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee P, et al. Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev. 2007;21:1050-63 pubmed
产品信息
品牌 :
Novus
master code :
NBP1-30141
SKU号 :
NBP1-30141
产品名称 :
组蛋白H3[三甲基化Lys9]抗体(6F12-H4)
描述 :
The Histone H3 [Trimethyl Lys9] Antibody (6F12-H4) from NBP1-30141 is a nbp1-30141 antibody to . This antibody reacts with chromatin modifiers, chromatin research, epigenetics, histones and modified histones, loading controls. The Histone H3 [Trimethyl Lys9] Antibody (6F12-H4) has been validated for the following applications: P84243, P84244.
靶标 :
组蛋白H3
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
三羟甲基氨基甲烷甘氨酸和0.15M氯化钠
克隆性 :
单克隆
克隆 :
6F12-H4
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
This Histone H3 [Trimethyl Lys9] antibody (6F12-H4) was raised against a synthetic peptide made to an N-terminal region of Histone H3 (between amino acids 1-50). [UniProt# P84243]
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
Human, Mouse, Rat, Porcine, C. elegans, Drosophila, Invertebrate, Mammal, Yeast
理论上的分子量 :
15 kDa
基因符号 :
H3C14
accessionNumbers :
P84243, P84244
应用 :
免疫印迹, 染色质免疫沉淀 , 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡
美元 :
379美元
别名 :
H3, H3组蛋白, 家族3A, H3.3A, H3.3B, H3F2, H3F3, H3组蛋白成员3B, H3FM, H3K9Me3, HIST2H3C, 组蛋白H3.3, MGC87782, MGC87783
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。