产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
FIH-1/HIF-1AN抗体(162c)
目录 :
NBP1-30333
规格 :
0.1 ml (also 0.025 ml)
价格 :
329美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
162c
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Wollenick K, Hu J, Kristiansen G, Schraml P, Rehrauer H, Berchner Pfannschmidt U, et al. Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling. Nucleic Acids Res. 2012;40:1928-43 pubmed 出版商
  • 免疫印迹; 人类
Khan M, Bhattacharyya T, Andrikopoulos P, Esteban M, Barod R, Connor T, et al. Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1?-mediated apoptosis. Br J Cancer. 2011;104:1151-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Yan M, Rayoo M, Takano E, Thorne H, Fox S. BRCA1 tumours correlate with a HIF-1alpha phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expression. Br J Cancer. 2009;101:1168-74 pubmed 出版商
  • 免疫印迹; 人类
Cockman M, Lancaster D, Stolze I, Hewitson K, McDonough M, Coleman M, et al. Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH). Proc Natl Acad Sci U S A. 2006;103:14767-72 pubmed
  • 免疫组化-石蜡切片; 人类
Soilleux E, Turley H, Tian Y, Pugh C, Gatter K, Harris A. Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues. Histopathology. 2005;47:602-10 pubmed
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Stolze I, Tian Y, Appelhoff R, Turley H, Wykoff C, Gleadle J, et al. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. J Biol Chem. 2004;279:42719-25 pubmed
Beel S, Kolloch L, Apken L, Jürgens L, Bolle A, Sudhof N, et al. κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis. Nat Commun. 2020;11:3409 pubmed 出版商
Krishnan A, Katsumi T, Guicciardi M, Azad A, Ozturk N, Trussoni C, et al. Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor Deficiency Promotes the Ductular Reaction, Macrophage Accumulation, and Hepatic Fibrosis in the Abcb4-/- Mouse. Am J Pathol. 2020;190:1284-1297 pubmed 出版商
Pickel C, Günter J, Ruiz Serrano A, Spielmann P, Fabrizio J, Wolski W, et al. Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1. Redox Biol. 2019;26:101265 pubmed 出版商
Tam P, Yiu R, Lendahl U, Andersson E. Cholangiopathies - Towards a molecular understanding. EBioMedicine. 2018;35:381-393 pubmed 出版商
Ma M, Hua S, Li G, Wang S, Cheng X, He S, et al. Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma. Oncotarget. 2017;8:12983-13002 pubmed 出版商
Mysore V, Szablowski J, Dervan P, FROST P. A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity. Mol Cancer Res. 2016;14:253-66 pubmed 出版商
Lu X, Zhou Y, Zhang L, Ji H, Li L, Shi Y, et al. Loss of Dicer1 impairs hepatocyte survival and leads to chronic inflammation and progenitor cell activation. World J Gastroenterol. 2015;21:6591-603 pubmed 出版商
Bird T, Lu W, Boulter L, Gordon Keylock S, Ridgway R, Williams M, et al. Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling. Proc Natl Acad Sci U S A. 2013;110:6542-7 pubmed 出版商
Dorrell C, Erker L, Schug J, Kopp J, Canaday P, Fox A, et al. Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev. 2011;25:1193-203 pubmed 出版商
Dorrell C, Grompe M, Pan F, Zhong Y, Canaday P, Shultz L, et al. Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers. Mol Cell Endocrinol. 2011;339:144-50 pubmed 出版商
Lu L, Li Y, Kim S, Bossuyt W, Liu P, Qiu Q, et al. Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci U S A. 2010;107:1437-42 pubmed 出版商
Dorrell C, Erker L, Lanxon Cookson K, Abraham S, Victoroff T, Ro S, et al. Surface markers for the murine oval cell response. Hepatology. 2008;48:1282-91 pubmed 出版商
产品信息
品牌 :
Novus
master code :
NBP1-30333
SKU号 :
NBP1-30333
产品名称 :
FIH-1/HIF-1AN抗体(162c)
描述 :
The FIH-1/HIF-1AN Antibody (162c) from NBP1-30333 is a nbp1-30333 antibody to . This antibody reacts with angiogenesis, cancer, chromatin research, hypoxia, transcription factors and regulators. The FIH-1/HIF-1AN Antibody (162c) has been validated for the following applications: Q9NWT6.
靶标 :
FIH-1/HIF-1AN
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
三羟甲基氨基甲烷甘氨酸和0.15M氯化钠
克隆性 :
单克隆
克隆 :
162c
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Full length human Factor Inhibiting HIF-1 protein [Swiss-Prot# Q9NWT6]
抗体亚型 :
IgG1
纯度 :
蛋白质G纯化
物种 :
人类
理论上的分子量 :
40 kDa
基因符号 :
HIF1AN
accessionNumbers :
Q9NWT6
应用 :
免疫印迹, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡
美元 :
329美元
别名 :
DKFZp762F1811, EC 1.14.11.16, factor inhibiting HIF1, Factor inhibiting HIF-1, FIH1FIH-1, FLJ20615, FLJ22027, hypoxia inducible factor 1, alpha subunit inhibitor, hypoxia-inducible factor 1-alpha inhibitor, Hypoxia-inducible factor asparagine hydroxylase, peptide-aspartate beta-dioxygenase
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。