产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
ATF6 Antibody (70B1413.1) - BSA Free
目录 :
NBP1-40256.1毫克
规格 :
0.1 mg (also 0.025 mg)
价格 :
449美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
70B1413.1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 224
参考文献
Sakuma I, Nagano H, Hashimoto N, Fujimoto M, Nakayama A, Fuchigami T, et al. Identification of genotype-biochemical phenotype correlations associated with fructose 1,6-bisphosphatase deficiency. Commun Biol. 2023;6:787 pubmed 出版商
Espina M, Di Franco N, Bra xf1 as Navarro M, Navarro I, Brito V, López Molina L, et al. The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice. Neurobiol Dis. 2023;184:106225 pubmed 出版商
Li J, Li S, Yu S, Yang J, Ke J, Li H, et al. Persistent ER stress causes GPI anchor deficit to convert a GPI-anchored prion protein into pro-PrP via the ATF6-miR449c-5p-PIGV axis. J Biol Chem. 2023;299:104982 pubmed 出版商
Kar A, Jain D, Kumar S, Rajput K, Pal S, Rana K, et al. A localized hydrogel-mediated chemotherapy causes immunogenic cell death via activation of ceramide-mediated unfolded protein response. Sci Adv. 2023;9:eadf2746 pubmed 出版商
Xiao J, Huang J, Jian X, Wang H, Lan H, Liao Z, et al. IRE1α arm of unfolded protein response in muscle-specific TGF-β signaling-mediated regulation of muscle cell immunological properties. Cell Mol Biol Lett. 2023;28:15 pubmed 出版商
Preston A, Rogers A, Sharp M, Mitchell G, Toruno C, Barney B, et al. Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria. Cell Death Discov. 2023;9:66 pubmed 出版商
Griffin H, Sullivan S, Barger S, Phelan K, Baldini G. Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis. Int J Mol Sci. 2022;24: pubmed 出版商
Cicalese S, Torimoto K, Okuno K, Elliott K, Rizzo V, Hashimoto T, et al. Endoplasmic Reticulum Chemical Chaperone 3-Hydroxy-2-Naphthoic Acid Reduces Angiotensin II-Induced Vascular Remodeling and Hypertension In Vivo and Protein Synthesis In Vitro. J Am Heart Assoc. 2022;11:e028201 pubmed 出版商
Byun J, Lebeau P, Platko K, Carlisle R, Faiyaz M, Chen J, et al. Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity. Kidney360. 2022;3:1394-1410 pubmed 出版商
Koepke L, Schwedhelm E, Ibing W, Oberhuber A, Daum G, Vcelar B, et al. Spinal Stroke: Outcome Attenuation by Erythropoietin and Carbamylated Erythropoietin and Its Prediction by Sphingosine-1-Phosphate Serum Levels in Mice. Int J Mol Sci. 2022;23: pubmed 出版商
Pritchard K, Jing X, Teng M, Wells C, Jia S, Afolayan A, et al. Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia. PLoS ONE. 2022;17:e0269564 pubmed 出版商
Abbonante V, Malara A, Chrisam M, Metti S, Soprano P, Semplicini C, et al. Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis. Autophagy. 2022;:1-16 pubmed 出版商
Hu J, Chang Y, Hsieh C, Huang S. The Synergistic Cytotoxic Effects of GW5074 and Sorafenib by Impacting Mitochondrial Functions in Human Colorectal Cancer Cell Lines. Front Oncol. 2022;12:925653 pubmed 出版商
Khoi C, Xiao C, Hung K, Lin T, Chiang C. Oxidative Stress-Induced Growth Inhibitor (OSGIN1), a Target of X-Box-Binding Protein 1, Protects Palmitic Acid-Induced Vascular Lipotoxicity through Maintaining Autophagy. Biomedicines. 2022;10: pubmed 出版商
Wadgaonkar P, Bi Z, Wan J, Fu Y, Zhang Q, Almutairy B, et al. Arsenic Activates the ER Stress-Associated Unfolded Protein Response via the Activating Transcription Factor 6 in Human Bronchial Epithelial Cells. Biomedicines. 2022;10: pubmed 出版商
Lin J, Lin Y, Liu J, Liu S, Fang K, Hsu R, et al. Norketamine, the Main Metabolite of Ketamine, Induces Mitochondria-Dependent and ER Stress-Triggered Apoptotic Death in Urothelial Cells via a Ca2+-Regulated ERK1/2-Activating Pathway. Int J Mol Sci. 2022;23: pubmed 出版商
Shibuya K, Ebihara K, Ebihara C, Sawayama N, Isoda M, Yamamuro D, et al. AAA-ATPase valosin-containing protein binds the transcription factor SREBP1 and promotes its proteolytic activation by rhomboid protease RHBDL4. J Biol Chem. 2022;298:101936 pubmed 出版商
Lu J, Xiong K, Qian X, Choi J, Shim Y, Burnett J, et al. Spata7 is required for maintenance of the retinal connecting cilium. Sci Rep. 2022;12:5575 pubmed 出版商
White A, Parekh R, Theobald D, Pakala P, Myers A, Van Dross R, et al. Kinin B1R Activation Induces Endoplasmic Reticulum Stress in Primary Hypothalamic Neurons. Front Pharmacol. 2022;13:841068 pubmed 出版商
Kyeong M, Lee J. Endogenous BiP reporter system for simultaneous identification of ER stress and antibody production in Chinese hamster ovary cells. Metab Eng. 2022;72:35-45 pubmed 出版商
Chen R, Michaeloudes C, Liang Y, Bhavsar P, Chung K, Ip M, et al. ORMDL3 regulates cigarette smoke-induced endoplasmic reticulum stress in airway smooth muscle cells. J Allergy Clin Immunol. 2022;149:1445-1457.e5 pubmed 出版商
Pan J, Sun D, Lee D, Xiong L, Ren X, Guo H, et al. Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence. Commun Biol. 2021;4:1326 pubmed 出版商
Kim H, Choi H, Cho G, Im J, Hong E, Chun H. Natural Thiols, but Not Thioethers, Attenuate Patulin-Induced Endoplasmic Reticulum Stress in HepG2 Cells. Toxins (Basel). 2021;13: pubmed 出版商
Guo H, Xiong L, Pan J, Lee D, Liu K, Ren X, et al. Hepcidin contributes to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss. Bone Res. 2021;9:31 pubmed 出版商
Kornicka Garbowska K, Bourebaba L, Röcken M, Marycz K. Sex Hormone Binding Globulin (SHBG) Mitigates ER Stress in Hepatocytes In Vitro and Ex Vivo. Cells. 2021;10: pubmed 出版商
Pandey R, Bakay M, Strenkowski B, Hain H, Hakonarson H. JAK/STAT inhibitor therapy partially rescues the lipodystrophic autoimmune phenotype in Clec16a KO mice. Sci Rep. 2021;11:7372 pubmed 出版商
Chen X, Li C, Liu J, He Y, Wei Y, Chen J. Inhibition of ER stress by targeting the IRE1α-TXNDC5 pathway alleviates crystalline silica-induced pulmonary fibrosis. Int Immunopharmacol. 2021;95:107519 pubmed 出版商
Cao X, An J, Cao Y, Lv J, Wang J, Ding Y, et al. EMC3 Is Essential for Retinal Organization and Neurogenesis During Mouse Retinal Development. Invest Ophthalmol Vis Sci. 2021;62:31 pubmed 出版商
Kalish B, Kim E, Finander B, Duffy E, Kim H, Gilman C, et al. Maternal immune activation in mice disrupts proteostasis in the fetal brain. Nat Neurosci. 2021;24:204-213 pubmed 出版商
Novais E, Choi H, Madhu V, Suyama K, Anjo S, Manadas B, et al. Hypoxia and Hypoxia-Inducible Factor-1α Regulate Endoplasmic Reticulum Stress in Nucleus Pulposus Cells: Implications of Endoplasmic Reticulum Stress for Extracellular Matrix Secretion. Am J Pathol. 2020;: pubmed 出版商
Menzie Suderam J, Modi J, Xu H, Bent A, Trujillo P, Medley K, et al. Granulocyte-colony stimulating factor gene therapy as a novel therapeutics for stroke in a mouse model. J Biomed Sci. 2020;27:99 pubmed 出版商
Lee D, Park S, Ahn J, Hong S, Lee E, Jang Y, et al. Mir214-3p and Hnf4a/Hnf4α reciprocally regulate Ulk1 expression and autophagy in nonalcoholic hepatic steatosis. Autophagy. 2020;:1-17 pubmed 出版商
Kim S, Lee S, Lee H, Ju S, Park S, Kwon D, et al. A Colon-Targeted Prodrug, 4-Phenylbutyric Acid-Glutamic Acid Conjugate, Ameliorates 2,4-Dinitrobenzenesulfonic Acid-Induced Colitis in Rats. Pharmaceutics. 2020;12: pubmed 出版商
Aryal Y, Lee E, Kim T, Sung S, Kim J, An S, et al. Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development. Gene Expr Patterns. 2020;37:119130 pubmed 出版商
Ganesan M, Mathews S, Makarov E, Petrosyan A, Kharbanda K, Kidambi S, et al. Acetaldehyde suppresses HBV-MHC class I complex presentation on hepatocytes via induction of ER stress and Golgi fragmentation. Am J Physiol Gastrointest Liver Physiol. 2020;319:G432-G442 pubmed 出版商
Cai E, Ishikawa Y, Zhang W, Leite N, Li J, Hou S, et al. Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes. Nat Metab. 2020;2:934-945 pubmed 出版商
Hotokezaka Y, Katayama I, Nakamura T. ATM-associated signalling triggers the unfolded protein response and cell death in response to stress. Commun Biol. 2020;3:378 pubmed 出版商
Benade J, Sher L, De Klerk S, Deshpande G, Bester D, Marnewick J, et al. The Impact of Sugar-Sweetened Beverage Consumption on the Liver: A Proteomics-based Analysis. Antioxidants (Basel). 2020;9: pubmed 出版商
Debernardi J, Pioche Durieu C, Cam E, Wiels J, Robert A. Verotoxin-1-Induced ER Stress Triggers Apoptotic or Survival Pathways in Burkitt Lymphoma Cells. Toxins (Basel). 2020;12: pubmed 出版商
Peserico D, Stranieri C, Garbin U, Mozzini C C, Danese E, Cominacini L, et al. Ezetimibe Prevents Ischemia/Reperfusion-Induced Oxidative Stress and Up-Regulates Nrf2/ARE and UPR Signaling Pathways. Antioxidants (Basel). 2020;9: pubmed 出版商
Iyer S, Melendez Suchi C, Han L, Baldini G, Almeida M, Jilka R. Elevation of the unfolded protein response increases RANKL expression. FASEB Bioadv. 2020;2:207-218 pubmed 出版商
Lähteenvuo J, Hätinen O, Kuivanen A, Huusko J, Paananen J, Lähteenvuo M, et al. Susceptibility to Cardiac Arrhythmias and Sympathetic Nerve Growth in VEGF-B Overexpressing Myocardium. Mol Ther. 2020;: pubmed 出版商
Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, et al. Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy. Nat Commun. 2020;11:1304 pubmed 出版商
Upadhyay A, Sinha R, Kumar A, Godbole M. Time-restricted feeding ameliorates maternal high-fat diet-induced fetal lung injury. Exp Mol Pathol. 2020;114:104413 pubmed 出版商
Yap J, Chen X, Delmotte P, Sieck G. TNFα selectively activates the IRE1α/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2020;318:L483-L493 pubmed 出版商
Modi J, Menzie Suderam J, Xu H, Trujillo P, Medley K, Marshall M, et al. Mode of action of granulocyte-colony stimulating factor (G-CSF) as a novel therapy for stroke in a mouse model. J Biomed Sci. 2020;27:19 pubmed 出版商
Yang B, Lu X, Li Y, Li Y, Yu D, Zhang W, et al. A Proteomic Network Approach across the Kidney Stone Disease Reveals Endoplasmic Reticulum Stress and Crystal-Cell Interaction in the Kidney. Oxid Med Cell Longev. 2019;2019:9307256 pubmed 出版商
Gu R, Huang T, Xiao J, Liao Z, Li J, Lan H, et al. The IRE1α Arm of UPR Regulates Muscle Cells Immune Characters by Restraining p38 MAPK Activation. Front Physiol. 2019;10:1198 pubmed 出版商
Coope A, Pascoal L, Botezelli J, da Silva F, Ayrizono M, Rodrigues B, et al. ER stress activation in the intestinal mucosa but not in mesenteric adipose tissue is associated with inflammation in Crohn's disease patients. PLoS ONE. 2019;14:e0223105 pubmed 出版商
Sun X, Zhang X, Zhai H, Zhang D, Ma S. Chicoric acid (CA) induces autophagy in gastric cancer through promoting endoplasmic reticulum (ER) stress regulated by AMPK. Biomed Pharmacother. 2019;118:109144 pubmed 出版商
Prieto K, Cao Y, Mohamed E, Trillo Tinoco J, Sierra R, Urueña C, et al. Polyphenol-rich extract induces apoptosis with immunogenic markers in melanoma cells through the ER stress-associated kinase PERK. Cell Death Discov. 2019;5:134 pubmed 出版商
Chung Y, Yen C, Tang F, Lee K, Liu S, Wu C, et al. Methylmercury exposure induces ROS/Akt inactivation-triggered endoplasmic reticulum stress-regulated neuronal cell apoptosis. Toxicology. 2019;425:152245 pubmed 出版商
Kirchner P, Bourdenx M, Madrigal Matute J, Tiano S, Díaz A, Bartholdy B, et al. Proteome-wide analysis of chaperone-mediated autophagy targeting motifs. PLoS Biol. 2019;17:e3000301 pubmed 出版商
Hernández Alvarez M, Sebastian D, Vives S, Ivanova S, Bartoccioni P, Kakimoto P, et al. Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease. Cell. 2019;177:881-895.e17 pubmed 出版商
Groenendyk J, Robinson A, Wang Q, Hu M, Tang J, Chen X, et al. Tauroursodeoxycholic acid attenuates cyclosporine-induced renal fibrogenesis in the mouse model. Biochim Biophys Acta Gen Subj. 2019;1863:1210-1216 pubmed 出版商
Wang F, Pulinilkunnil T, Flibotte S, Nislow C, Vlodavsky I, Hussein B, et al. Heparanase protects the heart against chemical or ischemia/reperfusion injury. J Mol Cell Cardiol. 2019;131:29-40 pubmed 出版商
Guo Q, Hu H, Liu X, Yang D, Yin Y, Zhang B, et al. C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes. Am J Physiol Endocrinol Metab. 2019;316:E1081-E1092 pubmed 出版商
Przystal J, Waramit S, Pranjol M, Yan W, Chu G, Chongchai A, et al. Efficacy of systemic temozolomide-activated phage-targeted gene therapy in human glioblastoma. EMBO Mol Med. 2019;11: pubmed 出版商
Kim J, Lee D, Jeong S, Kim B, Na Y, Park S, et al. Imatinib‑induced apoptosis of gastric cancer cells is mediated by endoplasmic reticulum stress. Oncol Rep. 2019;41:1616-1626 pubmed 出版商
Huang Q, Lan T, Lu J, Zhang H, Zhang D, Lou T, et al. DiDang Tang Inhibits Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Oxygen Glucose Deprivation and Intracerebral Hemorrhage Through Blockade of the GRP78-IRE1/PERK Pathways. Front Pharmacol. 2018;9:1423 pubmed 出版商
Thams S, Lowry E, Larraufie M, Spiller K, Li H, Williams D, et al. A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress. Mol Ther. 2019;27:87-101 pubmed 出版商
Ayaub E, Tandon K, Padwal M, Imani J, Patel H, Dubey A, et al. IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages. Immunol Cell Biol. 2019;97:203-217 pubmed 出版商
Fink E, Moparthy S, Bagati A, Bianchi Smiraglia A, Lipchick B, Wolff D, et al. XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response. Cell Rep. 2018;25:212-223.e4 pubmed 出版商
Pang X, Zhang Y, Shi X, Li D, Han J. ERp44 depletion exacerbates ER stress and aggravates diabetic nephropathy in db/db mice. Biochem Biophys Res Commun. 2018;504:921-926 pubmed 出版商
Burman A, Kropski J, Calvi C, Serezani A, Pascoalino B, Han W, et al. Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein. JCI Insight. 2018;3: pubmed 出版商
Ogata S, Kameda K, Kono T, Ozeki Y, Hashimoto H, Tominaga S, et al. Expressions of ATF6, XBP1, and GRP78 in normal tissue, atypical adenomatous hyperplasia, and adenocarcinoma of the lung. Hum Pathol. 2019;83:22-28 pubmed 出版商
Kristensen C, Dethlefsen M, Tøndering A, Lassen S, Meldgaard J, Ringholm S, et al. PGC-1α in hepatic UPR during high-fat high-fructose diet and exercise training in mice. Physiol Rep. 2018;6:e13819 pubmed 出版商
Lewis S, Takimoto T, Mehrvar S, Higuchi H, Doebley A, Stokes G, et al. The effect of Tmem135 overexpression on the mouse heart. PLoS ONE. 2018;13:e0201986 pubmed 出版商
Kristensen C, Olsen M, Jessen H, Brandt N, Meldgaard J, Pilegaard H. PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice. Pflugers Arch. 2018;470:1431-1447 pubmed 出版商
Kristensen C, Jessen H, Ringholm S, Pilegaard H. Muscle PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice. Acta Physiol (Oxf). 2018;224:e13158 pubmed 出版商
Deodati A, Argemi J, Germani D, Puglianiello A, Alisi A, De Stefanis C, et al. The exposure to uteroplacental insufficiency is associated with activation of unfolded protein response in postnatal life. PLoS ONE. 2018;13:e0198490 pubmed 出版商
Starr C, Pitale P, Gorbatyuk M. Translational attenuation and retinal degeneration in mice with an active integrated stress response. Cell Death Dis. 2018;9:484 pubmed 出版商
Lebeau P, Byun J, Yousof T, Austin R. Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death. Toxicol Appl Pharmacol. 2018;349:1-7 pubmed 出版商
Rubio Patiño C, Bossowski J, De Donatis G, Mondragon L, Villa E, Aira L, et al. Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance. Cell Metab. 2018;27:828-842.e7 pubmed 出版商
Guo J, Cui Y, Liu Q, Yang Y, Li Y, Weng L, et al. Piperine ameliorates SCA17 neuropathology by reducing ER stress. Mol Neurodegener. 2018;13:4 pubmed 出版商
Xue A, Lin J, Que C, Yu Y, Tu C, Chen H, et al. Aberrant endoplasmic reticulum stress mediates coronary artery spasm through regulating MLCK/MLC2 pathway. Exp Cell Res. 2018;363:321-331 pubmed 出版商
Park H, Park J, Kim J, Yang S, Jung J, Kim M, et al. Regulation of the Endoplasmic Reticulum Stress by BIP/GRP78 is involved in Meiotic Maturation of Porcine Oocytes In Vitro. Dev Reprod. 2017;21:407-415 pubmed 出版商
Amer S, Bhopale K, Kakumanu R, Popov V, Rampy B, El Mehallawi I, et al. Hepatic alcohol dehydrogenase deficiency induces pancreatic injury in chronic ethanol feeding model of deer mice. Exp Mol Pathol. 2018;104:89-97 pubmed 出版商
Hyer M, Milhollen M, Ciavarri J, Fleming P, Traore T, Sappal D, et al. A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment. Nat Med. 2018;24:186-193 pubmed 出版商
Huang Y, Shen Z, Wu C, Teng Y, Liao C, Kao C, et al. Comparative proteomic profiling reveals a role for Cisd2 in skeletal muscle aging. Aging Cell. 2017;: pubmed 出版商
Hao L, Sun Q, Zhong W, Zhang W, Sun X, Zhou Z. Mitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: A molecular mechanism of protection against alcoholic liver disease. Redox Biol. 2018;14:626-636 pubmed 出版商
Park H, Park J, Kim J, Yang S, Jung J, Kim M, et al. Melatonin improves the meiotic maturation of porcine oocytes by reducing endoplasmic reticulum stress during in vitro maturation. J Pineal Res. 2018;64: pubmed 出版商
Tang X, Snowball J, Xu Y, Na C, Weaver T, Clair G, et al. EMC3 coordinates surfactant protein and lipid homeostasis required for respiration. J Clin Invest. 2017;: pubmed 出版商
Doran A, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond C, et al. CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. J Clin Invest. 2017;127:4075-4089 pubmed 出版商
Lee S, Kim S, Hwang S, Cherrington N, Ryu D. Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver disease. Oncotarget. 2017;8:63370-63381 pubmed 出版商
Ahlstrom P, Rai E, Chakma S, Cho H, Rengasamy P, Sweeney G. Adiponectin improves insulin sensitivity via activation of autophagic flux. J Mol Endocrinol. 2017;59:339-350 pubmed 出版商
Kristensen C, Brandt C, Ringholm S, Pilegaard H. PGC-1? in aging and lifelong exercise training-mediated regulation of UPR in mouse liver. Exp Gerontol. 2017;98:124-133 pubmed 出版商
Carraro R, Souza G, Solon C, Razolli D, Chausse B, Barbizan R, et al. Hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity. Mol Cell Endocrinol. 2018;460:238-245 pubmed 出版商
Wang W, Liu W, Durnaoglu S, Lee S, Lian J, Lehner R, et al. Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis. Sci Rep. 2017;7:5941 pubmed 出版商
Pinkaew D, Chattopadhyay A, King M, Chunhacha P, Liu Z, Stevenson H, et al. Fortilin binds IRE1? and prevents ER stress from signaling apoptotic cell death. Nat Commun. 2017;8:18 pubmed 出版商
Kwon K, Kwon Y, Kim S, Yu K, Lee K, Kwon O. Luteolin-induced apoptosis through activation of endoplasmic reticulum stress sensors in pheochromocytoma cells. Mol Med Rep. 2017;16:380-386 pubmed 出版商
Freis P, Bollard J, Lebeau J, Massoma P, Fauvre J, Vercherat C, et al. mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines. Oncotarget. 2017;8:20974-20987 pubmed 出版商
Kemter E, Frohlich T, Arnold G, Wolf E, Wanke R. Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD). Sci Rep. 2017;7:42970 pubmed 出版商
Teng R, Jing X, Michalkiewicz T, Afolayan A, Wu T, Konduri G. Attenuation of endoplasmic reticulum stress by caffeine ameliorates hyperoxia-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2017;312:L586-L598 pubmed 出版商
Pinto A, da Rocha A, Pereira B, Oliveira L, Morais G, Moura L, et al. Excessive training is associated with endoplasmic reticulum stress but not apoptosis in the hypothalamus of mice. Appl Physiol Nutr Metab. 2017;42:354-360 pubmed 出版商
Liu J, Wang Y, Song L, Zeng L, Yi W, Liu T, et al. A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability. Nat Commun. 2017;8:14186 pubmed 出版商
Jin J, Blackwood E, Azizi K, Thuerauf D, Fahem A, Hofmann C, et al. ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart. Circ Res. 2017;120:862-875 pubmed 出版商
Tripathi M, Zhang C, Singh B, Sinha R, Moe K, DeSilva D, et al. Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation. Cell Death Dis. 2016;7:e2513 pubmed 出版商
Teng Y, Neo J, Wu J, Chen Y, Kao C, Tsai T. Expression of a hepatitis B virus pre-S2 deletion mutant in the liver results in hepatomegaly and hepatocellular carcinoma in mice. J Pathol. 2017;241:463-474 pubmed 出版商
Homma T, Fujii J. Heat stress promotes the down-regulation of IRE1? in cells: An atypical modulation of the UPR pathway. Exp Cell Res. 2016;349:128-138 pubmed 出版商
Fan Y, He J. HIV-1 Tat Induces Unfolded Protein Response and Endoplasmic Reticulum Stress in Astrocytes and Causes Neurotoxicity through Glial Fibrillary Acidic Protein (GFAP) Activation and Aggregation. J Biol Chem. 2016;291:22819-22829 pubmed
Kusama H, Kon K, Ikejima K, Arai K, Aoyama T, Uchiyama A, et al. Sodium 4-phenylbutyric acid prevents murine acetaminophen hepatotoxicity by minimizing endoplasmic reticulum stress. J Gastroenterol. 2017;52:611-622 pubmed 出版商
Kobylewski S, Henderson K, Yamada K, Eckhert C. Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake. Biol Trace Elem Res. 2017;176:278-293 pubmed 出版商
Krawczyk K, Ekman M, Rippe C, Grossi M, Nilsson B, Albinsson S, et al. Assessing the contribution of thrombospondin-4 induction and ATF6? activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction. Sci Rep. 2016;6:32449 pubmed 出版商
Barrera M, Aguilera S, Castro I, Cortes J, Bahamondes V, Quest A, et al. Pro-inflammatory cytokines enhance ERAD and ATF6? pathway activity in salivary glands of Sjögren's syndrome patients. J Autoimmun. 2016;75:68-81 pubmed 出版商
Pailler E, Oulhen M, Billiot F, Galland A, Auger N, Faugeroux V, et al. Method for semi-automated microscopy of filtration-enriched circulating tumor cells. BMC Cancer. 2016;16:477 pubmed 出版商
Shirato T, Homma T, Lee J, Kurahashi T, Fujii J. Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis. Arch Toxicol. 2017;91:1319-1333 pubmed 出版商
Sunami Y, Ringelhan M, Kokai E, Lu M, O CONNOR T, Lorentzen A, et al. Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response. Hepatology. 2016;63:1592-607 pubmed 出版商
Li Y, Zalzala M, Jadhav K, Xu Y, Kasumov T, Yin L, et al. Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice. Hepatology. 2016;63:1860-74 pubmed 出版商
Yang T, Yen C, Lee K, Su C, Yang C, Wu C, et al. Molybdenum induces pancreatic β-cell dysfunction and apoptosis via interdependent of JNK and AMPK activation-regulated mitochondria-dependent and ER stress-triggered pathways. Toxicol Appl Pharmacol. 2016;294:54-64 pubmed 出版商
Peng Y, Kim M, Hullinger R, O Riordan K, Burger C, Pehar M, et al. Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse. Brain. 2016;139:937-52 pubmed 出版商
Pereira B, da Rocha A, Pinto A, Pauli J, De Souza C, Cintra D, et al. Excessive eccentric exercise-induced overtraining model leads to endoplasmic reticulum stress in mice skeletal muscles. Life Sci. 2016;145:144-51 pubmed 出版商
Zhou H, Zhu J, Yue S, Lu L, Busuttil R, Kupiec Weglinski J, et al. The Dichotomy of Endoplasmic Reticulum Stress Response in Liver Ischemia-Reperfusion Injury. Transplantation. 2016;100:365-72 pubmed 出版商
Yu L, Andruska N, Zheng X, Shapiro D. Anticipatory activation of the unfolded protein response by epidermal growth factor is required for immediate early gene expression and cell proliferation. Mol Cell Endocrinol. 2016;422:31-41 pubmed 出版商
Mondal T, Emeny R, Gao D, Ault J, Kasten Jolly J, Lawrence D. A physical/psychological and biological stress combine to enhance endoplasmic reticulum stress. Toxicol Appl Pharmacol. 2015;289:313-22 pubmed 出版商
Sharma R, O Donnell A, Stamateris R, Ha B, McCloskey K, Reynolds P, et al. Insulin demand regulates β cell number via the unfolded protein response. J Clin Invest. 2015;125:3831-46 pubmed 出版商
Cai X, Chen L, McGinnis J. Correlation of ER stress and retinal degeneration in tubby mice. Exp Eye Res. 2015;140:130-138 pubmed 出版商
Li S, Guo L, Qian P, Zhao Y, Liu A, Ji F, et al. Lipopolysaccharide Induces Autophagic Cell Death through the PERK-Dependent Branch of the Unfolded Protein Response in Human Alveolar Epithelial A549 Cells. Cell Physiol Biochem. 2015;36:2403-17 pubmed 出版商
Ren F, Shi H, Zhang L, Zhang X, Wen T, Xie B, et al. The dysregulation of endoplasmic reticulum stress response in acute-on-chronic liver failure patients caused by acute exacerbation of chronic hepatitis B. J Viral Hepat. 2016;23:23-31 pubmed 出版商
Hrincius E, Liedmann S, Finkelstein D, Vogel P, Gansebom S, Samarasinghe A, et al. Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway. Cell Rep. 2015;11:1591-603 pubmed 出版商
Gharibani P, Modi J, Menzie J, Alexandrescu A, Ma Z, Tao R, et al. Comparison between single and combined post-treatment with S-Methyl-N,N-diethylthiolcarbamate sulfoxide and taurine following transient focal cerebral ischemia in rat brain. Neuroscience. 2015;300:460-73 pubmed 出版商
Yao F, Li Z, Ehara T, Yang L, Wang D, Feng L, et al. Fatty Acid-Binding Protein 4 mediates apoptosis via endoplasmic reticulum stress in mesangial cells of diabetic nephropathy. Mol Cell Endocrinol. 2015;411:232-42 pubmed 出版商
Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed 出版商
Wong M, Nicholson C, Holloway A, Hardy D. Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta. PLoS ONE. 2015;10:e0122295 pubmed 出版商
Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi V, et al. Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy. Nat Commun. 2015;6:6496 pubmed 出版商
Kung L, Rajpar M, Preziosi R, Briggs M, Boot Handford R. Increased classical endoplasmic reticulum stress is sufficient to reduce chondrocyte proliferation rate in the growth plate and decrease bone growth. PLoS ONE. 2015;10:e0117016 pubmed 出版商
Ren F, Zhou L, Zhang X, Wen T, Shi H, Xie B, et al. Endoplasmic reticulum stress-activated glycogen synthase kinase 3β aggravates liver inflammation and hepatotoxicity in mice with acute liver failure. Inflammation. 2015;38:1151-65 pubmed 出版商
Lu T, Su C, Tang F, Chen C, Yen C, Fang K, et al. Chloroacetic acid triggers apoptosis in neuronal cells via a reactive oxygen species-induced endoplasmic reticulum stress signaling pathway. Chem Biol Interact. 2015;225:1-12 pubmed 出版商
Bernard Marissal N, Sunyach C, Marissal T, Raoul C, Pettmann B. Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice. Neurobiol Dis. 2015;73:130-6 pubmed 出版商
Andruska N, Zheng X, Yang X, Helferich W, Shapiro D. Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor α-positive breast cancer. Oncogene. 2015;34:3760-9 pubmed 出版商
Dlugos C. ATF6 and caspase 12 expression in Purkinje neurons in acute slices from adult, ethanol-fed rats. Brain Res. 2014;1577:11-20 pubmed 出版商
Xu J, Wu F, Tian D, Wang J, Zheng Z, Xia N. Open reading frame 3 of genotype 1 hepatitis E virus inhibits nuclear factor-?appa B signaling induced by tumor necrosis factor-? in human A549 lung epithelial cells. PLoS ONE. 2014;9:e100787 pubmed 出版商
Liu L, Chowdhury S, Fang X, Liu J, Srikant C. Attenuation of unfolded protein response and apoptosis by mReg2 induced GRP78 in mouse insulinoma cells. FEBS Lett. 2014;588:2016-24 pubmed 出版商
Enos R, Velazquez K, Murphy E. Insight into the impact of dietary saturated fat on tissue-specific cellular processes underlying obesity-related diseases. J Nutr Biochem. 2014;25:600-12 pubmed 出版商
Mamrosh J, Lee J, Wagner M, Stambrook P, Whitby R, Sifers R, et al. Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution. elife. 2014;3:e01694 pubmed 出版商
Osborne B, Yao T, Wang X, Chen Y, Kotan L, Nadvi N, et al. A rare variant in human fibroblast activation protein associated with ER stress, loss of enzymatic function and loss of cell surface localisation. Biochim Biophys Acta. 2014;1844:1248-59 pubmed 出版商
Li M, Liu Y, Xia F, Wu Z, Deng L, Jiang R, et al. Progranulin is required for proper ER stress response and inhibits ER stress-mediated apoptosis through TNFR2. Cell Signal. 2014;26:1539-48 pubmed 出版商
Shao M, Shan B, Liu Y, Deng Y, Yan C, Wu Y, et al. Hepatic IRE1? regulates fasting-induced metabolic adaptive programs through the XBP1s-PPAR? axis signalling. Nat Commun. 2014;5:3528 pubmed 出版商
Choudhury S, Nashine S, Bhootada Y, Kunte M, Gorbatyuk O, Lewin A, et al. Modulation of the rate of retinal degeneration in T17M RHO mice by reprogramming the unfolded protein response. Adv Exp Med Biol. 2014;801:455-62 pubmed 出版商
Kaphalia L, Boroumand N, Hyunsu J, Kaphalia B, Calhoun W. Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding. Toxicol Appl Pharmacol. 2014;277:109-17 pubmed 出版商
Miller M, Rosenthal P, Beppu A, Mueller J, Hoffman H, Tam A, et al. ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma. J Immunol. 2014;192:3475-87 pubmed 出版商
Mohammad Gharibani P, Modi J, Menzie J, Genova R, Ma Z, Tao R, et al. Mode of action of S-methyl-N, N-diethylthiocarbamate sulfoxide (DETC-MeSO) as a novel therapy for stroke in a rat model. Mol Neurobiol. 2014;50:655-72 pubmed 出版商
Zeindl Eberhart E, Brandl L, Liebmann S, Ormanns S, Scheel S, Brabletz T, et al. Epithelial-mesenchymal transition induces endoplasmic-reticulum-stress response in human colorectal tumor cells. PLoS ONE. 2014;9:e87386 pubmed 出版商
Huang Y, Chang C, Tang C, Lin Y, Ju T, Huang W, et al. Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells. Cell Signal. 2014;26:611-8 pubmed 出版商
Tay K, Luan Q, Croft A, Jiang C, Jin L, Zhang X, et al. Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress. Cell Signal. 2014;26:287-94 pubmed 出版商
Bhuiyan M, Pattison J, Osinska H, James J, Gulick J, McLendon P, et al. Enhanced autophagy ameliorates cardiac proteinopathy. J Clin Invest. 2013;123:5284-97 pubmed 出版商
Yang C, Diiorio P, Jurczyk A, O Sullivan Murphy B, Urano F, Bortell R. Pathological endoplasmic reticulum stress mediated by the IRE1 pathway contributes to pre-insulitic beta cell apoptosis in a virus-induced rat model of type 1 diabetes. Diabetologia. 2013;56:2638-46 pubmed
Naidoo N, Davis J, Zhu J, Yabumoto M, Singletary K, Brown M, et al. Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell. 2014;13:131-41 pubmed 出版商
Thepparit C, Khakpoor A, Khongwichit S, Wikan N, Fongsaran C, Chingsuwanrote P, et al. Dengue 2 infection of HepG2 liver cells results in endoplasmic reticulum stress and induction of multiple pathways of cell death. BMC Res Notes. 2013;6:372 pubmed 出版商
Murray L, Lu Y, Taggart A, Van Regemorter N, Vilain C, Abramowicz M, et al. Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke. Hum Mol Genet. 2014;23:283-92 pubmed 出版商
Iwasaki Y, Suganami T, Hachiya R, Shirakawa I, Kim Saijo M, Tanaka M, et al. Activating transcription factor 4 links metabolic stress to interleukin-6 expression in macrophages. Diabetes. 2014;63:152-61 pubmed 出版商
Misiewicz M, Déry M, Foveau B, Jodoin J, Ruths D, LeBlanc A. Identification of a novel endoplasmic reticulum stress response element regulated by XBP1. J Biol Chem. 2013;288:20378-91 pubmed 出版商
Kamiya T, Hara H, Adachi T. Effect of endoplasmic reticulum (ER) stress inducer thapsigargin on the expression of extracellular-superoxide dismutase in mouse 3T3-L1 adipocytes. J Clin Biochem Nutr. 2013;52:101-5 pubmed 出版商
Storm P, Klausen T, Trulsson M, Ho C S J, Dosnon M, Westergren T, et al. A unifying mechanism for cancer cell death through ion channel activation by HAMLET. PLoS ONE. 2013;8:e58578 pubmed 出版商
Grall S, Prunier Mirebeau D, Tamareille S, Mateus V, Lamon D, Furber A, et al. Endoplasmic reticulum stress pathway involvement in local and remote myocardial ischemic conditioning. Shock. 2013;39:433-9 pubmed 出版商
Lind K, Ball K, Cruz N, Dienel G. The unfolded protein response to endoplasmic reticulum stress in cultured astrocytes and rat brain during experimental diabetes. Neurochem Int. 2013;62:784-95 pubmed 出版商
Schipanski A, Lange S, Segref A, Gutschmidt A, Lomas D, Miranda E, et al. A novel interaction between aging and ER overload in a protein conformational dementia. Genetics. 2013;193:865-76 pubmed 出版商
Kia A, Przystal J, Nianiaris N, Mazarakis N, Mintz P, Hajitou A. Dual systemic tumor targeting with ligand-directed phage and Grp78 promoter induces tumor regression. Mol Cancer Ther. 2012;11:2566-77 pubmed 出版商
Mans S, Banz Y, Mueller B, Pabst T. The angiogenesis inhibitor vasostatin is regulated by neutrophil elastase-dependent cleavage of calreticulin in AML patients. Blood. 2012;120:2690-9 pubmed
Marshall J, Holmberg J, Chou E, Ocampo A, Oh J, Lee J, et al. Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration. J Cell Biol. 2012;197:1009-27 pubmed 出版商
Zheng X, Wang X, Ma Z, Gupta Sunkari V, Botusan I, Takeda T, et al. Acute hypoxia induces apoptosis of pancreatic ?-cell by activation of the unfolded protein response and upregulation of CHOP. Cell Death Dis. 2012;3:e322 pubmed 出版商
Saporta M, Shy B, Patzkó A, Bai Y, Pennuto M, Ferri C, et al. MpzR98C arrests Schwann cell development in a mouse model of early-onset Charcot-Marie-Tooth disease type 1B. Brain. 2012;135:2032-47 pubmed 出版商
Burnett H, Audas T, Liang G, Lu R. Herpes simplex virus-1 disarms the unfolded protein response in the early stages of infection. Cell Stress Chaperones. 2012;17:473-83 pubmed 出版商
Ling S, Lau E, Al Shabeeb A, Nikolic A, Catalano A, Iland H, et al. Response of myeloma to the proteasome inhibitor bortezomib is correlated with the unfolded protein response regulator XBP-1. Haematologica. 2012;97:64-72 pubmed 出版商
Lian I, Løset M, Mundal S, Fenstad M, Johnson M, Eide I, et al. Increased endoplasmic reticulum stress in decidual tissue from pregnancies complicated by fetal growth restriction with and without pre-eclampsia. Placenta. 2011;32:823-9 pubmed 出版商
Akay C, Lindl K, Shyam N, Nabet B, Goenaga Vazquez Y, Ruzbarsky J, et al. Activation status of integrated stress response pathways in neurones and astrocytes of HIV-associated neurocognitive disorders (HAND) cortex. Neuropathol Appl Neurobiol. 2012;38:175-200 pubmed 出版商
Chiang C, Hsu S, Wu C, Huang J, Cheng H, Chang Y, et al. Endoplasmic reticulum stress implicated in the development of renal fibrosis. Mol Med. 2011;17:1295-305 pubmed 出版商
Michinaga S, Hisatsune A, Isohama Y, Katsuki H. Orexin neurons in hypothalamic slice cultures are vulnerable to endoplasmic reticulum stress. Neuroscience. 2011;190:289-300 pubmed 出版商
Jeyasuria P, Subedi K, Suresh A, Condon J. Elevated levels of uterine anti-apoptotic signaling may activate NFKB and potentially confer resistance to caspase 3-mediated apoptotic cell death during pregnancy in mice. Biol Reprod. 2011;85:417-24 pubmed 出版商
Oslowski C, Urano F. Measuring ER stress and the unfolded protein response using mammalian tissue culture system. Methods Enzymol. 2011;490:71-92 pubmed 出版商
Su Y, Wu J, Hong J. Betanodavirus up-regulates chaperone GRP78 via ER stress: roles of GRP78 in viral replication and host mitochondria-mediated cell death. Apoptosis. 2011;16:272-87 pubmed 出版商
Wang L, Popko B, Roos R. The unfolded protein response in familial amyotrophic lateral sclerosis. Hum Mol Genet. 2011;20:1008-15 pubmed 出版商
Chang K, Chen P, Chen Y, Chang Y, Su I. Dominant expression of survival signals of endoplasmic reticulum stress response in Hodgkin lymphoma. Cancer Sci. 2011;102:275-81 pubmed 出版商
Jia W, Loria R, Park M, Yacoub A, Dent P, Graf M. The neuro-steroid, 5-androstene 3?,17? diol; induces endoplasmic reticulum stress and autophagy through PERK/eIF2? signaling in malignant glioma cells and transformed fibroblasts. Int J Biochem Cell Biol. 2010;42:2019-29 pubmed 出版商
Lepine S, Allegood J, Park M, Dent P, Milstien S, Spiegel S. Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy. Cell Death Differ. 2011;18:350-61 pubmed 出版商
Deldicque L, Cani P, Philp A, Raymackers J, Meakin P, Ashford M, et al. The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesis. Am J Physiol Endocrinol Metab. 2010;299:E695-705 pubmed 出版商
Toko H, Takahashi H, Kayama Y, Okada S, Minamino T, Terasaki F, et al. ATF6 is important under both pathological and physiological states in the heart. J Mol Cell Cardiol. 2010;49:113-20 pubmed 出版商
Lithanatudom P, Leecharoenkiat A, Wannatung T, Svasti S, Fucharoen S, Smith D. A mechanism of ineffective erythropoiesis in ?-thalassemia/Hb E disease. Haematologica. 2010;95:716-23 pubmed 出版商
Xu Y, Guan D, Yang M, Wang H, Shen Z. All-trans-retinoic acid intensifies endoplasmic reticulum stress in N-acetylglucosaminyltransferase V repressed human hepatocarcinoma cells by perturbing homocysteine metabolism. J Cell Biochem. 2010;109:468-77 pubmed 出版商
Rajpar M, McDermott B, Kung L, Eardley R, Knowles L, Heeran M, et al. Targeted induction of endoplasmic reticulum stress induces cartilage pathology. PLoS Genet. 2009;5:e1000691 pubmed 出版商
Roboti P, Swanton E, High S. Differences in endoplasmic-reticulum quality control determine the cellular response to disease-associated mutants of proteolipid protein. J Cell Sci. 2009;122:3942-53 pubmed 出版商
Guan D, Xu Y, Yang M, Wang H, Wang X, Shen Z. N-acetyl cysteine and penicillamine induce apoptosis via the ER stress response-signaling pathway. Mol Carcinog. 2010;49:68-74 pubmed 出版商
Bommiasamy H, Back S, Fagone P, Lee K, Meshinchi S, Vink E, et al. ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum. J Cell Sci. 2009;122:1626-36 pubmed 出版商
Kim I, Shu C, Xu W, Shiau C, Grant D, Vasile S, et al. Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1. J Biol Chem. 2009;284:1593-603 pubmed 出版商
Hallaert D, Jaspers A, van Noesel C, van Oers M, Kater A, Eldering E. c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches. Blood. 2008;112:5141-9 pubmed 出版商
Jorgensen E, Stinson A, Shan L, Yang J, Gietl D, Albino A. Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells. BMC Cancer. 2008;8:229 pubmed 出版商
Chen J, Wu M, Huang K, Lin W. HMG-CoA reductase inhibitors activate the unfolded protein response and induce cytoprotective GRP78 expression. Cardiovasc Res. 2008;80:138-50 pubmed 出版商
Zhu Y, Fenik P, Zhan G, Sanfillipo Cohn B, Naidoo N, Veasey S. Eif-2a protects brainstem motoneurons in a murine model of sleep apnea. J Neurosci. 2008;28:2168-78 pubmed 出版商
Kerbiriou M, Le Drévo M, Ferec C, Trouvé P. Coupling cystic fibrosis to endoplasmic reticulum stress: Differential role of Grp78 and ATF6. Biochim Biophys Acta. 2007;1772:1236-49 pubmed
Lee S, Lee M, Cherla R, Tesh V. Shiga toxin 1 induces apoptosis through the endoplasmic reticulum stress response in human monocytic cells. Cell Microbiol. 2008;10:770-80 pubmed
Wei H, Kim S, Zhang Z, Tsai P, Wisniewski K, Mukherjee A. ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones. Hum Mol Genet. 2008;17:469-77 pubmed
Kim D, Jeong S, Kim H, Kim D, Chae S, Chae H. Effects of triglyceride on ER stress and insulin resistance. Biochem Biophys Res Commun. 2007;363:140-5 pubmed
Kim K, Pae H, Zheng M, Park R, Kim Y, Chung H. Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress. Circ Res. 2007;101:919-27 pubmed
Roberts G, Di Loreto M, Marshall M, Wang J, DeGracia D. Hippocampal cellular stress responses after global brain ischemia and reperfusion. Antioxid Redox Signal. 2007;9:2265-75 pubmed
Piróg Garcia K, Meadows R, Knowles L, Heinegard D, Thornton D, Kadler K, et al. Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP. Hum Mol Genet. 2007;16:2072-88 pubmed
Rahmani M, Davis E, Crabtree T, Habibi J, Nguyen T, Dent P, et al. The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress. Mol Cell Biol. 2007;27:5499-513 pubmed
Mao W, Fukuoka S, Iwai C, Liu J, Sharma V, Sheu S, et al. Cardiomyocyte apoptosis in autoimmune cardiomyopathy: mediated via endoplasmic reticulum stress and exaggerated by norepinephrine. Am J Physiol Heart Circ Physiol. 2007;293:H1636-45 pubmed
Renna M, Caporaso M, Bonatti S, Kaufman R, Remondelli P. Regulation of ERGIC-53 gene transcription in response to endoplasmic reticulum stress. J Biol Chem. 2007;282:22499-512 pubmed
Lee G, Kim H, Chae S, Kim D, Ha K, Cuddy M, et al. Bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression. J Biol Chem. 2007;282:21618-28 pubmed
Davenport E, Moore H, Dunlop A, Sharp S, Workman P, Morgan G, et al. Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells. Blood. 2007;110:2641-9 pubmed
Ou Y, Yang C, Cheng C, Raung S, Hung Y, Chen C. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT. Eur J Pharmacol. 2007;563:49-60 pubmed
Laybutt D, Preston A, Akerfeldt M, Kench J, Busch A, Biankin A, et al. Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes. Diabetologia. 2007;50:752-63 pubmed
Nagy G, Kardon T, Wunderlich L, Szarka A, Kiss A, Schaff Z, et al. Acetaminophen induces ER dependent signaling in mouse liver. Arch Biochem Biophys. 2007;459:273-9 pubmed
Yu C, Hsu Y, Liao C, Lin Y. Flavivirus infection activates the XBP1 pathway of the unfolded protein response to cope with endoplasmic reticulum stress. J Virol. 2006;80:11868-80 pubmed
Williams B, Lipkin W. Endoplasmic reticulum stress and neurodegeneration in rats neonatally infected with borna disease virus. J Virol. 2006;80:8613-26 pubmed
Renna M, Faraonio R, Bonatti S, De Stefano D, Carnuccio R, Tajana G, et al. Nitric oxide-induced endoplasmic reticulum stress activates the expression of cargo receptor proteins and alters the glycoprotein transport to the Golgi complex. Int J Biochem Cell Biol. 2006;38:2040-8 pubmed
Nyborg A, Ladd T, Jansen K, Kukar T, Golde T. Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase. FASEB J. 2006;20:1671-9 pubmed
Van Kollenburg B, van Dijk J, Garbern J, Thomas A, Scheper G, Powers J, et al. Glia-specific activation of all pathways of the unfolded protein response in vanishing white matter disease. J Neuropathol Exp Neurol. 2006;65:707-15 pubmed
Donati G, Imbriano C, Mantovani R. Dynamic recruitment of transcription factors and epigenetic changes on the ER stress response gene promoters. Nucleic Acids Res. 2006;34:3116-27 pubmed
DuRose J, Tam A, Niwa M. Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress. Mol Biol Cell. 2006;17:3095-107 pubmed
Kikuchi H, Almer G, Yamashita S, Guegan C, Nagai M, Xu Z, et al. Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model. Proc Natl Acad Sci U S A. 2006;103:6025-30 pubmed
Bailly Maitre B, Fondevila C, Kaldas F, Droin N, Luciano F, Ricci J, et al. Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2006;103:2809-14 pubmed
Okumura A, Hatsuzawa K, Tamura T, Nagaya H, Saeki K, Okumura F, et al. Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system. J Biol Chem. 2006;281:4495-506 pubmed
Abdelrahim M, Newman K, Vanderlaag K, Samudio I, Safe S. 3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5. Carcinogenesis. 2006;27:717-28 pubmed
Keller S, Platoshyn O, Yuan J. Long QT syndrome-associated I593R mutation in HERG potassium channel activates ER stress pathways. Cell Biochem Biophys. 2005;43:365-77 pubmed
Thomas M, Yu Z, Dadgar N, Varambally S, Yu J, Chinnaiyan A, et al. The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor. J Biol Chem. 2005;280:21264-71 pubmed
Xu W, Liu L, Charles I, Moncada S. Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response. Nat Cell Biol. 2004;6:1129-34 pubmed
Tessitore A, Del P Martin M, Sano R, Ma Y, Mann L, Ingrassia A, et al. GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis. Mol Cell. 2004;15:753-66 pubmed
Park H, Tomida A, Sato S, Tsukumo Y, Yun J, Yamori T, et al. Effect on tumor cells of blocking survival response to glucose deprivation. J Natl Cancer Inst. 2004;96:1300-10 pubmed
Nyborg A, Jansen K, Ladd T, Fauq A, Golde T. A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin. J Biol Chem. 2004;279:43148-56 pubmed
Hong M, Li M, Mao C, Lee A. Endoplasmic reticulum stress triggers an acute proteasome-dependent degradation of ATF6. J Cell Biochem. 2004;92:723-32 pubmed
Hong M, Luo S, Baumeister P, Huang J, Gogia R, Li M, et al. Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response. J Biol Chem. 2004;279:11354-63 pubmed
Jenner R, Maillard K, Cattini N, Weiss R, Boshoff C, Wooster R, et al. Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile. Proc Natl Acad Sci U S A. 2003;100:10399-404 pubmed
Luo S, Lee A. Requirement of the p38 mitogen-activated protein kinase signalling pathway for the induction of the 78 kDa glucose-regulated protein/immunoglobulin heavy-chain binding protein by azetidine stress: activating transcription factor 6 as a target for str. Biochem J. 2002;366:787-95 pubmed
图像
图像 1 :
Novus Biologicals NBP1-40256-0.1mg 图像 1
Western Blot: ATF6 Antibody (70B1413.1) [NBP1-40256] - Hypoxia leads to EMT and ER-stress in CRC cells. B. C. Confluent growing SW480 (B) and HCT116 (C) cells were cultured under conditions of normoxia or hypoxia-like conditions (serum free; 100 uM CoCl2, 1-9 h. B-actin (B-act) as loading control. HIF1a was detectable after 3 h of CoCl2 incubation, the amount of the 50 kD-ATF6 fragment, was already enhanced after 1 h of addition of CoCl2. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0087386) licensed under a CC-BY licence.
产品信息
品牌 :
Novus
MasterCode :
NBP1-40256
SKU号 :
NBP1-40256.1毫克
产品名称 :
ATF6 Antibody (70B1413.1) - BSA Free
描述 :
The ATF6 Antibody (70B1413.1) - BSA Free from NBP1-40256-0.1mg is a nbp1-40256 antibody to . This antibody reacts with lipid and metabolism, signal transduction, unfolded protein response, unfolded protein response (upr). The ATF6 Antibody (70B1413.1) - BSA Free has been validated for the following applications: P18850.
靶标 :
转录激活因子6
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.025 mg)
缓冲液 :
TBS
克隆性 :
单克隆
克隆 :
70B1413.1
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
This monoclonal antibody was made against a partial protein containing amino acids 1-273 of human ATF6.
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠, 猪, 植物, 兔
特异性 :
This ATF6 antibody detects both the full length and the cleaved/active protein
基因符号 :
转录激活因子6
accessionNumbers :
P18850
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Flow (Intracellular), Chromatin Immunoprecipitation (ChIP), CyTOF-ready, Knockout Validated
美元 :
449美元
别名 :
activating transcription factor 6, Activating transcription factor 6 alpha, atf6 a, ATF6A, ATF6-alpha, cAMP-dependent transcription factor ATF-6 alpha, cyclic AMP-dependent transcription factor ATF-6 alpha
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。