产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
乳腺癌1号基因抗体(17F8)
目录 :
NBP1-41185
规格 :
100微升
价格 :
459美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
17F8
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 11
参考文献
Manchana T, Tantbirojn P, Pohthipornthawat N. BRCA immunohistochemistry for screening of BRCA mutation in epithelial ovarian cancer patients. Gynecol Oncol Rep. 2020;33:100582 pubmed 出版商
Zheng X, Fernando V, Sharma V, Walia Y, Letson J, Furuta S. Correction of arginine metabolism with sepiapterin-the precursor of nitric oxide synthase cofactor BH4-induces immunostimulatory-shift of breast cancer. Biochem Pharmacol. 2020;176:113887 pubmed 出版商
Rogers K, Moreno S, Smith L, Husson H, Bukanov N, Ledbetter S, et al. Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD. Physiol Rep. 2016;4: pubmed 出版商
Bosviel R, Dumollard E, Dechelotte P, Bignon Y, Bernard Gallon D. Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer?. OMICS. 2012;16:235-44 pubmed 出版商
Vardi A, Bosviel R, Rabiau N, Adjakly M, Satih S, Dechelotte P, et al. Soy phytoestrogens modify DNA methylation of GSTP1, RASSF1A, EPH2 and BRCA1 promoter in prostate cancer cells. In Vivo. 2010;24:393-400 pubmed
Bernard Gallon D, Dechelotte P, Le Corre L, Chalabi N, Vissac Sabatier C, Bignon Y. Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia. Anticancer Res. 2004;24:321-4 pubmed
Ongusaha P, Ouchi T, Kim K, Nytko E, Kwak J, Duda R, et al. BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest. Oncogene. 2003;22:3749-58 pubmed
Bernard Gallon D, Dechelotte P, Vissac C, Aunoble B, Cravello L, Malpuech G, et al. BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite. Breast Cancer Res. 2001;3:61-5 pubmed
Lu M, Arrick B. Transactivation of the p21 promoter by BRCA1 splice variants in mammary epithelial cells: evidence for both common and distinct activities of wildtype and mutant forms. Oncogene. 2000;19:6351-60 pubmed
de Toledo S, Azzam E, Dahlberg W, Gooding T, Little J. ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation. Oncogene. 2000;19:6185-93 pubmed
Arizti P, Fang L, Park I, Yin Y, Solomon E, Ouchi T, et al. Tumor suppressor p53 is required to modulate BRCA1 expression. Mol Cell Biol. 2000;20:7450-9 pubmed
产品信息
品牌 :
Novus
MasterCode :
NBP1-41185
SKU号 :
NBP1-41185
产品名称 :
乳腺癌1号基因抗体(17F8)
描述 :
The BRCA1 Antibody (17F8) from NBP1-41185 is a nbp1-41185 antibody to . This antibody reacts with apoptosis, breast cancer, cancer, cell biology, chromatin research, dna double strand break repair, dna repair, homologous recombination, tumor suppressors, ubiquitin proteasome pathway, zinc finger.
靶标 :
乳腺癌1号基因
类别 :
一抗
单位尺寸 :
100微升
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
17F8
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Protein fragment expressed in E. coli corresponding to amino acids 762-1315.
抗体亚型 :
IgG1
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠
特异性 :
This antibody does not recognize the delta exon 11 splice variant of BRCA1
理论上的分子量 :
208 kDa
基因符号 :
乳腺癌1号基因
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(17F8)-Western-Blot-NBP1-41185-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(17F8)-Chromatin-Immunoprecipitation-NBP1-41185-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(17F8)-Western-Blot-NBP1-41185-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/BRCA1-Antibody-(17F8)-Immunoprecipitation-NBP1-41185-img0006.jpg
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡, 染色质免疫沉淀 (ChIP)
美元 :
459美元
别名 :
BRCAI, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein, breast cancer 1, early onset, breast cancer type 1 susceptibility protein, EC 6.3.2, EC 6.3.2.-, IRIS, PNCA4, PSCP, subunit 1
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。