产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
半胱天冬酶1抗体
目录 :
NBP1-45433
规格 :
0.1 mg (also 20 ug)
价格 :
429美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
13A9
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 52
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:100; 图 6a
Rumfield C, Hyseni I, McBride J, Walker D, Fang R. Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection. Infect Immun. 2020;88: pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 7a
Yu J, Wang W, Matei N, Li X, Pang J, Mo J, et al. Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats. Oxid Med Cell Longev. 2020;2020:4717258 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 5c
Zhou K, Enkhjargal B, Xie Z, Sun C, Wu L, Malaguit J, et al. Dihydrolipoic Acid Inhibits Lysosomal Rupture and NLRP3 Through Lysosome-Associated Membrane Protein-1/Calcium/Calmodulin-Dependent Protein Kinase II/TAK1 Pathways After Subarachnoid Hemorrhage in Rat. Stroke. 2018;49:175-183 pubmed 出版商
Lu Y, Nanayakkara G, Sun Y, Liu L, Xu K, Drummer C, et al. Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation. Redox Biol. 2021;47:102142 pubmed 出版商
Liu X, Liu H, Lu X, Zhao S. N-acetylcysteine alleviates ocular surface damage in STZ-induced diabetic mice by inhibiting the ROS/NLRP3/Caspase-1/IL-1β signaling pathway. Exp Eye Res. 2021;209:108654 pubmed 出版商
Zhou K, Enkhjargal B, Mo J, Zhang T, Zhu Q, Wu P, et al. Dihydrolipoic acid enhances autophagy and alleviates neurological deficits after subarachnoid hemorrhage in rats. Exp Neurol. 2021;342:113752 pubmed 出版商
Liang H, Matei N, McBride D, Xu Y, Zhou Z, Tang J, et al. TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats. J Neuroinflammation. 2021;18:40 pubmed 出版商
Jiang S, Zhang H, Li X, Yi B, Huang L, Hu Z, et al. Vitamin D/VDR attenuate cisplatin-induced AKI by down-regulating NLRP3/Caspase-1/GSDMD pyroptosis pathway. J Steroid Biochem Mol Biol. 2021;206:105789 pubmed 出版商
Li L, Zou Y, Liu B, Yang R, Yang J, Sun M, et al. Contribution of the P2X4 Receptor in Rat Hippocampus to the Comorbidity of Chronic Pain and Depression. ACS Chem Neurosci. 2020;11:4387-4397 pubmed 出版商
Zhang Q, Wang J, Huang F, Yao Y, Xu L. Leptin induces NAFLD progression through infiltrated CD8+ T lymphocytes mediating pyroptotic-like cell death of hepatocytes and macrophages. Dig Liver Dis. 2020;: pubmed 出版商
Lim J, Lee H, Jung Y, Kim J, Chae C, Kim S, et al. Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation. Cell Commun Signal. 2020;18:123 pubmed 出版商
Wang C, Jia Q, Sun C, Jing C. Calcium sensing receptor contribute to early brain injury through the CaMKII/NLRP3 pathway after subarachnoid hemorrhage in mice. Biochem Biophys Res Commun. 2020;530:651-657 pubmed 出版商
Verma V, Kumar P, Gupta S, Yadav S, Dhanda R, Thorlacius H, et al. α-Hemolysin of uropathogenic E. coli regulates NLRP3 inflammasome activation and mitochondrial dysfunction in THP-1 macrophages. Sci Rep. 2020;10:12653 pubmed 出版商
Shi Y, Shi X, Liang J, Luo J, Ba J, Chen J, et al. Aggravated MRSA pneumonia secondary to influenza A virus infection is derived from decreased expression of IL-1β. J Med Virol. 2020;: pubmed 出版商
Saber S, Abd El Kader E, Sharaf H, El Shamy R, El Saeed B, Mostafa A, et al. Celastrol augments sensitivity of NLRP3 to CP-456773 by modulating HSP-90 and inducing autophagy in dextran sodium sulphate-induced colitis in rats. Toxicol Appl Pharmacol. 2020;400:115075 pubmed 出版商
Liu G, Baird A, Parsons M, Fan K, Skerrett Byrne D, Nair P, et al. Platelet activating factor receptor acts to limit colitis-induced liver inflammation. FASEB J. 2020;34:7718-7732 pubmed 出版商
Kim H, Seo J, Lee S, Ha K, Choi B, Shin Y, et al. AIM2 inflammasome contributes to brain injury and chronic post-stroke cognitive impairment in mice. Brain Behav Immun. 2020;87:765-776 pubmed 出版商
Wei H, Bu R, Yang Q, Jia J, Li T, Wang Q, et al. Exendin-4 Protects against Hyperglycemia-Induced Cardiomyocyte Pyroptosis via the AMPK-TXNIP Pathway. J Diabetes Res. 2019;2019:8905917 pubmed 出版商
Verma V, Gupta S, Kumar P, Yadav S, Dhanda R, Gaind R, et al. Involvement of NLRP3 and NLRC4 Inflammasome in Uropathogenic E. coli Mediated Urinary Tract Infections. Front Microbiol. 2019;10:2020 pubmed 出版商
Zhao S, Zhou Y, Fan Y, Gong Y, Yang J, Yang R, et al. Involvement of purinergic 2X4 receptor in glycoprotein 120-induced pyroptosis in dorsal root ganglia. J Neurochem. 2019;: pubmed 出版商
Liu B, Mao X, Huang D, Li F, Dong N. Novel role of NLRP3-inflammasome in regulation of lipogenesis in fasting-induced hepatic steatosis. Diabetes Metab Syndr Obes. 2019;12:801-811 pubmed 出版商
Mohammed S, Torres Luquis O, Walls E, Lloyd F. Lymph-circulating tumor cells show distinct properties to blood-circulating tumor cells and are efficient metastatic precursors. Mol Oncol. 2019;13:1400-1418 pubmed 出版商
Zhao K, Li X, Chen X, Zhu Q, Yin F, Ruan Q, et al. Inhibition of miR-140-3p or miR-155-5p by antagomir treatment sensitize chordoma cells to chemotherapy drug treatment by increasing PTEN expression. Eur J Pharmacol. 2019;854:298-306 pubmed 出版商
Liu G, Mateer S, Hsu A, Goggins B, Tay H, Mathe A, et al. Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome. Mucosal Immunol. 2019;: pubmed 出版商
Hlavac N, VandeVord P. Astrocyte Mechano-Activation by High-Rate Overpressure Involves Alterations in Structural and Junctional Proteins. Front Neurol. 2019;10:99 pubmed 出版商
Ren W, Hou J, Yang C, Wang H, Wu S, Wu Y, et al. Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery. J Exp Clin Cancer Res. 2019;38:62 pubmed 出版商
Chiba Y, He B, Yoshizaki K, Rhodes C, Ishijima M, Bleck C, et al. The transcription factor AmeloD stimulates epithelial cell motility essential for tooth morphology. J Biol Chem. 2019;294:3406-3418 pubmed 出版商
Lopes de Oliveira G, Alarcón de la Lastra C, Rosillo M, Castejon Martinez M, Sanchez Hidalgo M, Rolim Medeiros J, et al. Preventive effect of bergenin against the development of TNBS-induced acute colitis in rats is associated with inflammatory mediators inhibition and NLRP3/ASC inflammasome signaling pathways. Chem Biol Interact. 2019;297:25-33 pubmed 出版商
Che C, Li C, Lin J, Zhang J, Jiang N, Yuan K, et al. Wnt5a contributes to dectin-1 and LOX-1 induced host inflammatory response signature in Aspergillus fumigatus keratitis. Cell Signal. 2018;52:103-111 pubmed 出版商
Park S, Kim H, Kim K, Roh S. Sonic hedgehog signalling regulates the self-renewal and proliferation of skin-derived precursor cells in mice. Cell Prolif. 2018;51:e12500 pubmed 出版商
Chen N, Ou Z, Zhang W, Zhu X, Li P, Gong J. Cathepsin B regulates non-canonical NLRP3 inflammasome pathway by modulating activation of caspase-11 in Kupffer cells. Cell Prolif. 2018;51:e12487 pubmed 出版商
Mandal P, Feng Y, Lyons J, Berger S, Otani S, DeLaney A, et al. Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock. Immunity. 2018;49:42-55.e6 pubmed 出版商
Chen C, Melo E, Jakob P, Friedlein A, Elsässer B, Goettig P, et al. N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration. Matrix Biol. 2018;70:84-101 pubmed 出版商
Melo E, Oertle P, Trepp C, Meistermann H, Burgoyne T, Sborgi L, et al. HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model. EBioMedicine. 2018;27:258-274 pubmed 出版商
Hu Q, Zhang T, Yi L, Zhou X, Mi M. Dihydromyricetin inhibits NLRP3 inflammasome-dependent pyroptosis by activating the Nrf2 signaling pathway in vascular endothelial cells. Biofactors. 2018;44:123-136 pubmed 出版商
Chen M, Zhu X, Ran L, Lang H, Yi L, Mi M. Trimethylamine-N-Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3-SOD2-mtROS Signaling Pathway. J Am Heart Assoc. 2017;6: pubmed 出版商
Farjood F, Vargis E. Physical disruption of cell-cell contact induces VEGF expression in RPE cells. Mol Vis. 2017;23:431-446 pubmed
Lee H, Lee S, Kim N, Park K, Choi B, Shin Y, et al. Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke. J Biophotonics. 2017;10:1502-1513 pubmed 出版商
Lin C, Chao H, Li Z, Xu X, Liu Y, Bao Z, et al. Omega-3 fatty acids regulate NLRP3 inflammasome activation and prevent behavior deficits after traumatic brain injury. Exp Neurol. 2017;290:115-122 pubmed 出版商
Koeppen A, Becker A, Feustel P, Gelman B, Mazurkiewicz J. The significance of intercalated discs in the pathogenesis of Friedreich cardiomyopathy. J Neurol Sci. 2016;367:171-6 pubmed 出版商
Draganov D, Gopalakrishna Pillai S, Chen Y, Zuckerman N, Moeller S, Wang C, et al. Modulation of P2X4/P2X7/Pannexin-1 sensitivity to extracellular ATP via Ivermectin induces a non-apoptotic and inflammatory form of cancer cell death. Sci Rep. 2015;5:16222 pubmed 出版商
Michelhaugh S, Guastella A, Varadarajan K, Klinger N, Parajuli P, Ahmad A, et al. Development of patient-derived xenograft models from a spontaneously immortal low-grade meningioma cell line, KCI-MENG1. J Transl Med. 2015;13:227 pubmed 出版商
Chow A, Ng L, Lam C, Wong S, Wan T, Cheng N, et al. The Enhanced metastatic potential of hepatocellular carcinoma (HCC) cells with sorafenib resistance. PLoS ONE. 2013;8:e78675 pubmed 出版商
Maeda M, Johnson E, Mandal S, Lawson K, Keim S, Svoboda R, et al. Expression of inappropriate cadherins by epithelial tumor cells promotes endocytosis and degradation of E-cadherin via competition for p120(ctn). Oncogene. 2006;25:4595-604 pubmed
Jaggi M, Nazemi T, Abrahams N, Baker J, Galich A, Smith L, et al. N-cadherin switching occurs in high Gleason grade prostate cancer. Prostate. 2006;66:193-9 pubmed
Wahl J, Kim Y, Cullen J, Johnson K, Wheelock M. N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane. J Biol Chem. 2003;278:17269-76 pubmed
Van Aken E, Papeleu P, De Potter P, Bruyneel E, Philippe J, Seregard S, et al. Structure and function of the N-cadherin/catenin complex in retinoblastoma. Invest Ophthalmol Vis Sci. 2002;43:595-602 pubmed
Reyes Mugica M, Meyerhardt J, Rzasa J, Rimm D, Johnson K, Wheelock M, et al. Truncated DCC reduces N-cadherin/catenin expression and calcium-dependent cell adhesion in neuroblastoma cells. Lab Invest. 2001;81:201-10 pubmed
Kim J, Islam S, Kim Y, Prudoff R, Sass K, Wheelock M, et al. N-Cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motility. J Cell Biol. 2000;151:1193-206 pubmed
Mialhe A, Levacher G, Champelovier P, Martel V, Serres M, Knudsen K, et al. Expression of E-, P-, n-cadherins and catenins in human bladder carcinoma cell lines. J Urol. 2000;164:826-35 pubmed
Nieman M, Prudoff R, Johnson K, Wheelock M. N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J Cell Biol. 1999;147:631-44 pubmed
Makrigiannakis A, Coukos G, Christofidou Solomidou M, Gour B, Radice G, Blaschuk O, et al. N-cadherin-mediated human granulosa cell adhesion prevents apoptosis: a role in follicular atresia and luteolysis?. Am J Pathol. 1999;154:1391-406 pubmed
产品信息
品牌 :
Novus
master code :
NBP1-45433
SKU号 :
NBP1-45433
产品名称 :
半胱天冬酶1抗体
描述 :
The Caspase-1 Antibody from NBP1-45433 is a nbp1-45433 antibody to . This antibody reacts with apoptosis, cancer, caspases, cell biology, inflammation, innate immunity, lipid and metabolism. The Caspase-1 Antibody has been validated for the following applications: NP_150636.
靶标 :
半胱天冬酶1
类别 :
一抗
单位尺寸 :
0.1 mg (also 20 ug)
缓冲液 :
PBS(pH值7.2), 0.5 mM乙二胺四乙酸, 0.5% BSA, 30% 甘油
克隆性 :
多克隆
浓度 :
0.5毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
Caspase-1 Antibody was developed against a synthetic peptide surrounding amino acid 132 of human caspase-1 (NP_150636).
抗体亚型 :
IgG
纯度 :
亲和纯化
物种 :
人类, 小鼠, 大鼠, 大肠杆菌
特异性 :
Caspase-1 Antibody recognizes the 45 kDa procaspase-1 and the 20 kDa cleaved product
基因符号 :
胱天蛋白酶凋亡相关半胱氨酸肽酶1
accessionNumbers :
NP_150636
应用 :
免疫印迹, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡, 基因敲减验证
美元 :
429美元
别名 :
CASP1, CASP-1, CASP1 nirs variant 1, caspase 1, apoptosis-related cysteine peptidase, caspase-1, Caspase-1 subunit p10, Caspase-1 subunit p20, EC 3.4.22.36, EC:3.4.22.36, ICE, IL-1 beta-converting enzyme, IL1BC, IL-1BC, IL1BCE, IL1B-convertase, interleukin 1, beta, convertase, interleukin 1-B converting enzyme, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。