产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
钙粘蛋白N抗体(13A9)
目录 :
NBP1-48309
规格 :
0.1 ml (also 0.025 ml)
价格 :
429美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
13A9
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 图 s1
Hlavac N, VandeVord P. Astrocyte Mechano-Activation by High-Rate Overpressure Involves Alterations in Structural and Junctional Proteins. Front Neurol. 2019;10:99 pubmed 出版商
  • 免疫印迹; 人类
Chow A, Ng L, Lam C, Wong S, Wan T, Cheng N, et al. The Enhanced metastatic potential of hepatocellular carcinoma (HCC) cells with sorafenib resistance. PLoS ONE. 2013;8:e78675 pubmed 出版商
  • 免疫印迹; 人类
Maeda M, Johnson E, Mandal S, Lawson K, Keim S, Svoboda R, et al. Expression of inappropriate cadherins by epithelial tumor cells promotes endocytosis and degradation of E-cadherin via competition for p120(ctn). Oncogene. 2006;25:4595-604 pubmed
  • 免疫组化-石蜡切片; 人类
Jaggi M, Nazemi T, Abrahams N, Baker J, Galich A, Smith L, et al. N-cadherin switching occurs in high Gleason grade prostate cancer. Prostate. 2006;66:193-9 pubmed
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Wahl J, Kim Y, Cullen J, Johnson K, Wheelock M. N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane. J Biol Chem. 2003;278:17269-76 pubmed
  • 流式细胞仪; 人类
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Van Aken E, Papeleu P, De Potter P, Bruyneel E, Philippe J, Seregard S, et al. Structure and function of the N-cadherin/catenin complex in retinoblastoma. Invest Ophthalmol Vis Sci. 2002;43:595-602 pubmed
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Reyes Mugica M, Meyerhardt J, Rzasa J, Rimm D, Johnson K, Wheelock M, et al. Truncated DCC reduces N-cadherin/catenin expression and calcium-dependent cell adhesion in neuroblastoma cells. Lab Invest. 2001;81:201-10 pubmed
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Kim J, Islam S, Kim Y, Prudoff R, Sass K, Wheelock M, et al. N-Cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motility. J Cell Biol. 2000;151:1193-206 pubmed
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Nieman M, Prudoff R, Johnson K, Wheelock M. N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J Cell Biol. 1999;147:631-44 pubmed
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Makrigiannakis A, Coukos G, Christofidou Solomidou M, Gour B, Radice G, Blaschuk O, et al. N-cadherin-mediated human granulosa cell adhesion prevents apoptosis: a role in follicular atresia and luteolysis?. Am J Pathol. 1999;154:1391-406 pubmed
  • 免疫细胞化学; 大鼠
  • 免疫印迹; 大鼠
Benson D, Tanaka H. N-cadherin redistribution during synaptogenesis in hippocampal neurons. J Neurosci. 1998;18:6892-904 pubmed
  • 免疫细胞化学; 人类
Navarro P, Ruco L, Dejana E. Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization. J Cell Biol. 1998;140:1475-84 pubmed
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Islam S, Carey T, Wolf G, Wheelock M, Johnson K. Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion. J Cell Biol. 1996;135:1643-54 pubmed
  • 免疫细胞化学; 人类
Peralta Soler A, Knudsen K, Jaurand M, Johnson K, Wheelock M, Klein Szanto A, et al. The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas. Hum Pathol. 1995;26:1363-9 pubmed
  • 免疫沉淀; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Knudsen K, Soler A, Johnson K, Wheelock M. Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol. 1995;130:67-77 pubmed
  • 免疫印迹; 人类
Sacco P, McGranahan T, Wheelock M, Johnson K. Identification of plakoglobin domains required for association with N-cadherin and alpha-catenin. J Biol Chem. 1995;270:20201-6 pubmed
x15a wierczewska M, Sterzy x144 ska K, Ruci x144 ski M, Andrzejewska M, Nowicki M, Januchowski R. The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids. Biomed Pharmacother. 2023;165:115152 pubmed 出版商
Huang M, Wang C, Yao Y, Li H, Yao Y, Zhu Y, et al. Mebendazole-Induced Blood-Testis Barrier Injury in Mice Testes by Disrupting Microtubules in Addition to Triggering Programmed Cell Death. Int J Mol Sci. 2022;23: pubmed 出版商
Karim S, Burzangi A, Ahmad A, Siddiqui N, Ibrahim I, Sharma P, et al. PI3K-AKT Pathway Modulation by Thymoquinone Limits Tumor Growth and Glycolytic Metabolism in Colorectal Cancer. Int J Mol Sci. 2022;23: pubmed 出版商
Prasad A, Mahmood A, Gupta R, Bisoyi P, Saleem N, Naga Prasad S, et al. In cardiac muscle cells, both adrenergic agonists and antagonists induce reactive oxygen species from NOX2 but mutually attenuate each other's effects. Eur J Pharmacol. 2021;908:174350 pubmed 出版商
Matta R, Yousafzai M, Murrell M, Gonzalez A. Endothelial cell secreted metalloproteinase-2 enhances neural stem cell N-cadherin expression, clustering, and migration. FASEB J. 2021;35:e21311 pubmed 出版商
Padder R, Bhat Z, Ahmad Z, Singh N, Husain M. DRP1 Promotes BRAFV600E-Driven Tumor Progression and Metabolic Reprogramming in Colorectal Cancer. Front Oncol. 2020;10:592130 pubmed 出版商
Sáenz de Santa María I, Celada L, San José Martínez A, Cubiella T, Chiara M. Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2. Cancers (Basel). 2020;12: pubmed 出版商
Beauchamp P, Jackson C, Ozhathil L, Agarkova I, Galindo C, Sawyer D, et al. 3D Co-culture of hiPSC-Derived Cardiomyocytes With Cardiac Fibroblasts Improves Tissue-Like Features of Cardiac Spheroids. Front Mol Biosci. 2020;7:14 pubmed 出版商
Mohammed S, Torres Luquis O, Walls E, Lloyd F. Lymph-circulating tumor cells show distinct properties to blood-circulating tumor cells and are efficient metastatic precursors. Mol Oncol. 2019;13:1400-1418 pubmed 出版商
Zhao K, Li X, Chen X, Zhu Q, Yin F, Ruan Q, et al. Inhibition of miR-140-3p or miR-155-5p by antagomir treatment sensitize chordoma cells to chemotherapy drug treatment by increasing PTEN expression. Eur J Pharmacol. 2019;854:298-306 pubmed 出版商
Ren W, Hou J, Yang C, Wang H, Wu S, Wu Y, et al. Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery. J Exp Clin Cancer Res. 2019;38:62 pubmed 出版商
Chiba Y, He B, Yoshizaki K, Rhodes C, Ishijima M, Bleck C, et al. The transcription factor AmeloD stimulates epithelial cell motility essential for tooth morphology. J Biol Chem. 2019;294:3406-3418 pubmed 出版商
Park S, Kim H, Kim K, Roh S. Sonic hedgehog signalling regulates the self-renewal and proliferation of skin-derived precursor cells in mice. Cell Prolif. 2018;51:e12500 pubmed 出版商
Chen C, Melo E, Jakob P, Friedlein A, Elsässer B, Goettig P, et al. N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration. Matrix Biol. 2018;70:84-101 pubmed 出版商
Melo E, Oertle P, Trepp C, Meistermann H, Burgoyne T, Sborgi L, et al. HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model. EBioMedicine. 2018;27:258-274 pubmed 出版商
Becker A, Qian J, Gelman B, Yang M, Bauer P, Koeppen A. Heart and Nervous System Pathology in Compound Heterozygous Friedreich Ataxia. J Neuropathol Exp Neurol. 2017;76:665-675 pubmed 出版商
Farjood F, Vargis E. Physical disruption of cell-cell contact induces VEGF expression in RPE cells. Mol Vis. 2017;23:431-446 pubmed
Koeppen A, Becker A, Feustel P, Gelman B, Mazurkiewicz J. The significance of intercalated discs in the pathogenesis of Friedreich cardiomyopathy. J Neurol Sci. 2016;367:171-6 pubmed 出版商
Michelhaugh S, Guastella A, Varadarajan K, Klinger N, Parajuli P, Ahmad A, et al. Development of patient-derived xenograft models from a spontaneously immortal low-grade meningioma cell line, KCI-MENG1. J Transl Med. 2015;13:227 pubmed 出版商
Mialhe A, Levacher G, Champelovier P, Martel V, Serres M, Knudsen K, et al. Expression of E-, P-, n-cadherins and catenins in human bladder carcinoma cell lines. J Urol. 2000;164:826-35 pubmed
Peralta Soler A, Knudsen K, Tecson Miguel A, McBrearty F, Han A, Salazar H. Expression of E-cadherin and N-cadherin in surface epithelial-stromal tumors of the ovary distinguishes mucinous from serous and endometrioid tumors. Hum Pathol. 1997;28:734-9 pubmed
Han A, Peralta Soler A, Knudsen K, Wheelock M, Johnson K, Salazar H. Differential expression of N-cadherin in pleural mesotheliomas and E-cadherin in lung adenocarcinomas in formalin-fixed, paraffin-embedded tissues. Hum Pathol. 1997;28:641-5 pubmed
Hazan R, Kang L, Whooley B, Borgen P. N-cadherin promotes adhesion between invasive breast cancer cells and the stroma. Cell Adhes Commun. 1997;4:399-411 pubmed
产品信息
品牌 :
Novus
MasterCode :
NBP1-48309
SKU号 :
NBP1-48309
产品名称 :
钙粘蛋白N抗体(13A9)
描述 :
The N-Cadherin Antibody (13A9) from NBP1-48309 is a nbp1-48309 antibody to . This antibody reacts with cancer, cell cycle and replication, cellular markers, extracellular matrix, mesenchymal stem cell markers, neuroscience, plasma membrane markers, signal transduction, stem cells. The N-Cadherin Antibody (13A9) has been validated for the following applications: P19022.
靶标 :
钙粘蛋白N
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
13A9
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
This N-Cadherin Antibody (13A9) was developed against the cytoplasmic domain of human N Cadherin [Swiss-Prot# P19022].
抗体亚型 :
IgG1
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠
理论上的分子量 :
140 kDa
基因符号 :
CDH2
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunocytochemistry-NBP1-48309-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunocytochemistry-NBP1-48309-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Western-Blot-NBP1-48309-img0029.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Western-Blot-NBP1-48309-img0029.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Western-Blot-NBP1-48309-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Western-Blot-NBP1-48309-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunocytochemistry-NBP1-48309-img0026.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunocytochemistry-NBP1-48309-img0026.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Flow-(Intracellular)-NBP1-48309-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Flow-(Intracellular)-NBP1-48309-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Simple-Western-NBP1-48309-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Simple-Western-NBP1-48309-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin Antibody (13A9)-Western Blot-NBP1-48309-img0032.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin Antibody (13A9)-Western Blot-NBP1-48309-img0032.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunocytochemistry-Immunofluorescence-NBP1-48309-img0027.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunocytochemistry-Immunofluorescence-NBP1-48309-img0027.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunohistochemistry-NBP1-48309-img0031.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunohistochemistry-NBP1-48309-img0031.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Flow-Cytometry-NBP1-48309-img0030.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Flow-Cytometry-NBP1-48309-img0030.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunocytochemistry-Immunofluorescence-NBP1-48309-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunocytochemistry-Immunofluorescence-NBP1-48309-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunohistochemistry-NBP1-48309-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunohistochemistry-NBP1-48309-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunohistochemistry-Paraffin-NBP1-48309-img0028.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Immunohistochemistry-Paraffin-NBP1-48309-img0028.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Flow-Cytometry-NBP1-48309-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/N-Cadherin-Antibody-(13A9)-Flow-Cytometry-NBP1-48309-img0016.jpg
accessionNumbers :
P19022
应用 :
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Flow (Intracellular), Immunocytochemistry
美元 :
429美元
别名 :
ACOGS, ARVD14, cadherin 2, type 1, N-cadherin (neuronal), cadherin-2, calcium-dependent adhesion protein, neuronal, CD325, CD325 antigen, CDH2, CDHN, CDw325, NCAD, N-cadherin, N-cadherin 1, Neural cadherin, neural-cadherin
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。