产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
PD-L1 Antibody - BSA Free
目录 :
NBP1-76769
规格 :
0.1 mg (also 0.025 mg)
价格 :
499美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
DyLight680
克隆名称 :
6H12
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 34
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 图 6
Zhang J, Qi J, Wei H, Lei Y, Yu H, Liu N, et al. TGFβ1 in Cancer-Associated Fibroblasts Is Associated With Progression and Radiosensitivity in Small-Cell Lung Cancer. Front Cell Dev Biol. 2021;9:667645 pubmed 出版商
  • 免疫印迹; 人类; 图 4g
Mondal T, Shivange G, Tihagam R, Lyerly E, Battista M, Talwar D, et al. Unexpected PD-L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies. EMBO Mol Med. 2021;13:e12716 pubmed 出版商
Zhong Y, Li M, Han L, Tai Y, Cao S, Li J, et al. Galangin inhibits programmed cell death-ligand 1 expression by suppressing STAT3 and MYC and enhances T cell tumor-killing activity. Phytomedicine. 2023;116:154877 pubmed 出版商
Caron J, Han X, Lary C, Sathyanarayana P, Remick S, Ernstoff M, et al. Targeting the secreted RGDKGE collagen fragment reduces PD‑L1 by a proteasome‑dependent mechanism and inhibits tumor growth. Oncol Rep. 2023;49: pubmed 出版商
Dong M, Qian M, Ruan Z. CUL3/SPOP complex prevents immune escape and enhances chemotherapy sensitivity of ovarian cancer cells through degradation of PD-L1 protein. J Immunother Cancer. 2022;10: pubmed 出版商
Luo Z, Liao T, Zhang Y, Zheng H, Sun Q, Han F, et al. Ex vivo anchored PD-L1 functionally prevent in vivo renal allograft rejection. Bioeng Transl Med. 2022;7:e10316 pubmed 出版商
Riondato F, Colitti B, Rosati S, Sini F, Martini V. A method to test antibody cross-reactivity toward animal antigens for flow cytometry. Cytometry A. 2022;: pubmed 出版商
Sakuma K, Kii T, Takahashi H, Suzuki S, Yoshikawa K, Ogawa T, et al. An In Vivo Study of Local Administration of Low-dose Anti-PD-1 Antibody Using an Oral Cancer Cell Line. Anticancer Res. 2022;42:4293-4303 pubmed 出版商
Yang W, Han B, Chen Y, Geng F. SAAL1, a novel oncogene, is associated with prognosis and immunotherapy in multiple types of cancer. Aging (Albany NY). 2022;14:6316-6337 pubmed 出版商
Xia W, Zhang S, Duan H, Wang C, Qian S, Shen H. The combination therapy of Everolimus and anti-PD-1 improves the antitumor effect by regulating CD8+ T cells in bladder cancer. Med Oncol. 2022;39:37 pubmed 出版商
Chakrabarti J, Koh V, Steele N, Hawkins J, Ito Y, Merchant J, et al. Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids. Cancers (Basel). 2021;13: pubmed 出版商
Ravindran Menon D, Li Y, Yamauchi T, Osborne D, Vaddi P, Wempe M, et al. EGCG Inhibits Tumor Growth in Melanoma by Targeting JAK-STAT Signaling and Its Downstream PD-L1/PD-L2-PD1 Axis in Tumors and Enhancing Cytotoxic T-Cell Responses. Pharmaceuticals (Basel). 2021;14: pubmed 出版商
Koikawa K, Kibe S, Suizu F, Sekino N, Kim N, Manz T, et al. Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy. Cell. 2021;184:4753-4771.e27 pubmed 出版商
Sun T, Li M, Zhang Z, Wang J, Xing Y, Ri M, et al. Usnic acid suppresses cervical cancer cell proliferation by inhibiting PD-L1 expression and enhancing T-lymphocyte tumor-killing activity. Phytother Res. 2021;35:3916-3935 pubmed 出版商
Liu X, Xing Y, Li M, Zhang Z, Wang J, Ri M, et al. Licochalcone A inhibits proliferation and promotes apoptosis of colon cancer cell by targeting programmed cell death-ligand 1 via the NF-κB and Ras/Raf/MEK pathways. J Ethnopharmacol. 2021;273:113989 pubmed 出版商
Yang A, Li M, Zhang Z, Wang J, Xing Y, Ri M, et al. Erianin regulates programmed cell death ligand 1 expression and enhances cytotoxic T lymphocyte activity. J Ethnopharmacol. 2021;273:113598 pubmed 出版商
Holokai L, Chakrabarti J, Lundy J, Croagh D, Adhikary P, Richards S, et al. Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma. Cancers (Basel). 2020;12: pubmed 出版商
Zhou J, Wu Z, Hu J, Yang D, Chen X, Wang Q, et al. High-throughput single-EV liquid biopsy: Rapid, simultaneous, and multiplexed detection of nucleic acids, proteins, and their combinations. Sci Adv. 2020;6: pubmed 出版商
Tsutaho A, Hashimoto A, Hashimoto S, Hata S, Kachi S, Hirano S, et al. High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer. Cell Commun Signal. 2020;18:101 pubmed 出版商
Li Z, Zhang C, Du J, Zhao J, Shi M, Jin M, et al. Adipocytes promote tumor progression and induce PD-L1 expression via TNF-α/IL-6 signaling. Cancer Cell Int. 2020;20:179 pubmed 出版商
Liu C, Ma Z, Cai Z, Zhang F, Liu C, Chen T, et al. Identification of primordial germ cell-like cells as liver metastasis initiating cells in mouse tumour models. Cell Discov. 2020;6:15 pubmed 出版商
Yang Q, Peng J, Shi K, Xiao Y, Liu Q, Han R, et al. Rationally designed peptide-conjugated gold/platinum nanosystem with active tumor-targeting for enhancing tumor photothermal-immunotherapy. J Control Release. 2019;308:29-43 pubmed 出版商
Wang X, Wu W, Gao J, Li Z, Dong B, Lin X, et al. Autophagy inhibition enhances PD-L1 expression in gastric cancer. J Exp Clin Cancer Res. 2019;38:140 pubmed 出版商
Holokai L, Chakrabarti J, Broda T, Chang J, Hawkins J, Sundaram N, et al. Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection. PLoS Pathog. 2019;15:e1007468 pubmed 出版商
Chakrabarti J, Holokai L, Syu L, Steele N, Chang J, Wang J, et al. Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer. Oncotarget. 2018;9:37439-37457 pubmed 出版商
Xing Y, Mi C, Wang Z, Zhang Z, Li M, Zuo H, et al. Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death-ligand 1 expression by reducing hypoxia-inducible factor-1α and STAT3. Pharmacol Res. 2018;135:166-180 pubmed 出版商
Maisel K, Merrilees M, Atochina Vasserman E, Lian L, Obraztsova K, Rue R, et al. Immune Checkpoint Ligand PD-L1 is Upregulated in Pulmonary Lymphangioleiomyomatosis (LAM). Am J Respir Cell Mol Biol. 2018;: pubmed 出版商
Zhang P, Liu J, Li W, Li S, Han X. Lactoferricin B reverses cisplatin resistance in head and neck squamous cell carcinoma cells through targeting PD-L1. Cancer Med. 2018;: pubmed 出版商
He H, Zhou Y, Zhou Y, Zhuang J, He X, Wang S, et al. Dexmedetomidine mitigates microglia-mediated neuroinflammation through up-regulation of programmed cell death protein 1 in a rat spinal cord injury model. J Neurotrauma. 2018;: pubmed 出版商
Sun J, Lian M, Ma H, Wang R, Ma Z, Wang H, et al. Competing endogenous RNA network analysis of CD274, IL‑10 and FOXP3 co‑expression in laryngeal squamous cell carcinoma. Mol Med Rep. 2018;17:3859-3869 pubmed 出版商
D Arrigo P, Russo M, Rea A, Tufano M, Guadagno E, Del Basso De Caro M, et al. A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma. Oncotarget. 2017;8:68291-68304 pubmed 出版商
Gravelle P, Burroni B, Péricart S, Rossi C, Bezombes C, Tosolini M, et al. Mechanisms of PD-1/PD-L1 expression and prognostic relevance in non-Hodgkin lymphoma: a summary of immunohistochemical studies. Oncotarget. 2017;8:44960-44975 pubmed 出版商
Bronchud M, Tresserra F, Xu W, Warren S, Cusidó M, Zantop B, et al. Placental immune editing switch (PIES): learning about immunomodulatory pathways from a unique case report. Oncotarget. 2016;7:83817-83827 pubmed 出版商
Aguilar L, Shirley L, Chung V, Marsh C, Walker J, Coyle W, et al. Gene-mediated cytotoxic immunotherapy as adjuvant to surgery or chemoradiation for pancreatic adenocarcinoma. Cancer Immunol Immunother. 2015;64:727-36 pubmed 出版商
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NBP1-76769
SKU号 :
NBP1-76769
产品名称 :
PD-L1 Antibody - BSA Free
描述 :
The PD-L1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to PD-L1. This antibody reacts with human, mouse, rat. The PD-L1 Antibody - BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunohistochemistry Whole-Mount, Immunofluorescence, Knockdown Validated, Dual RNAscope ISH-IHC.
靶标 :
PD-L1
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.025 mg)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
Antibody was raised against a 17 amino acid synthetic peptide from near the center of human PD-L1. The immunogen is located within amino acids 60-110 of PD-L1.
抗体亚型 :
IgG
纯度 :
肽亲和纯化
物种 :
人类, 小鼠, 大鼠
特异性 :
PD-L1 antibody has no cross-reactivity to PD-L2
理论上的分子量 :
37 kDa
基因符号 :
CD274
accessionNumbers :
NP_054862
应用 :
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunohistochemistry Whole-Mount, Immunofluorescence, Knockdown Validated, Dual RNAscope ISH-IHC
美元 :
499美元
别名 :
Avelumab, B7-H, B7-H1, B7H1PDCD1L1, CD274 antigenMGC142294, CD274 molecule, PDCD1LG1MGC142296, PD-L1, PD-L1B7 homolog 1, PDL1PDCD1 ligand 1, programmed cell death 1 ligand 1, Programmed death ligand 1
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。